Page last updated: 2024-09-04

ivabradine and Bradyarrhythmia

ivabradine has been researched along with Bradyarrhythmia in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (5.56)	18.2507
2000's	4 (11.11)	29.6817
2010's	22 (61.11)	24.3611
2020's	8 (22.22)	2.80

Authors

Authors	Studies
Hofmann, F; Ludwig, A; Stieber, J; Stöckl, G; Wieland, K	1
Gluud, C; Jakobsen, JC; Liang, N; Maagaard, M; Nielsen, EE; Sethi, NJ; Yang, SH	1
Crossley, DA; Joyce, W; Smith, B; Wang, T	1
Alagarraju, MR; Joshi, PH; Kulkarni, N; Poklis, JL; Singh, K; Tharpe, W; Wolf, CE	1
Lockette, W; Miller, C; Student, J; Woodman, R	1
Alexandrovich, A; Arbel Ganon, L; Davoodi, M; Yaniv, Y	1
Abdin, A; Batailler, C; Böhm, M; Borer, J; Ford, I; Komajda, M; Mahfoud, F; Slawik, J; Swedberg, K; Tavazzi, L	1
Bartelds, B; de Hoog, M; de Jonge, RC; In 't Veld, YL; Kammeraad, J; Koch, BCP; Sassen, SD; Sylva, M	1
Allalou, A; Ameur, A; Brooke, HL; de Geus, E; den Hoed, M; Dethlefsen, O; Emmanouilidou, A; Höijer, I; Ingelsson, E; Jumaa, S; Klingström, T; Mazzaferro, E; Snieder, H; Vicenzi, S; von der Heyde, B	1
Hayama, Y; Kawada, T; Nishikawa, T; Shimizu, S; Shishido, T; Sugimachi, M; Uemura, K; Yamamoto, H	1
Belardinelli, L; Machado, AD; Nearing, BD; Sobrado, LF; Varone, BB; Verrier, RL; Zeng, D	1
Lakatta, EG; Maltsev, VA; Sirenko, S; Spurgeon, HA; Yaniv, Y; Ziman, BD	1
Huang, Y; Jiang, J; Li, Y; Tian, L; Xu, L	1
Dulaurent, S; Gaulier, JM; Julia, F; Mathiaux, F	1
Mittal, SR	1
Somlói, M; Toldy-Schedel, E; Tomcsányi, J	1
Brack, KE; Dempsey, CE; El Harchi, A; Hancox, JC; Melgari, D; Mitcheson, JS; Ng, GA; Zhang, C; Zhang, Y	1
Gómez Casal, V; Lage Cendon, L; Lago Preciado, G; Vara Adrio, S	1
Ferrari, R; Ford, I; Fox, K; Steg, PG; Tardif, JC; Tendera, M	1
Lüscher, TF	1
Brinkmann, J; Diedrich, A; Großhennig, A; Heusser, K; Jordan, J; Luft, FC; May, M; Mehling, H; Schroeder, C; Sweep, FC; Tank, J; Wenzel, D	1
Maskell, K; Troendle, M; Tse, A; Wolf, CE	1
Díez-García, LF; Gálvez-Contreras, MC; Romero-León, JM	2
Davis, K; Dietrich, E	1
Morales-Martínez de Tejada, Á	1
Bolduc, V; Des Rosiers, C; Lachance, D; Lauzier, B; Rivard, ME; Ruiz, M; Shi, Y; Tardif, JC; Thorin, E; Vaillant, F	1
Alshammari, TM	1
Christensen, LP; Tomanek, RJ; Zhang, RL	1
Kaehler, J; Koester, R; Meinertz, T	1
Brunetti, ND; Cademartiri, F; Di Biase, L; Di Biase, M; Guaricci, AI; Ieva, R; Macarini, L; Maffei, E; Midiri, M; Montrone, D; Schuijf, JD; Tedeschi, C	1
DiFrancesco, D	1
Camm, AJ; Savelieva, I	2
Bennett, T; Gardiner, SM; Kemp, PA; March, JE	1
Bel, A; Faris, B; Menasché, P; Mouas, C; Perrault, LP; Vilaine, JP	1

Reviews

6 review(s) available for ivabradine and Bradyarrhythmia

Article	Year
Ivabradine added to usual care in patients with heart failure: a systematic review with meta-analysis and trial sequential analysis. BMJ evidence-based medicine, 2022, Volume: 27, Issue:4 Topics: Atrial Fibrillation; Bradycardia; Heart Failure; Humans; Ivabradine; Myocardial Infarction; Quality of Life	2022
Ivabradine (Corlanor) for Heart Failure. American family physician, 2016, Apr-15, Volume: 93, Issue:8 Topics: Atrial Fibrillation; Benzazepines; Bradycardia; Cardiovascular Agents; Drug Costs; Heart Failure; Humans; Hypertension; Ivabradine; Treatment Outcome	2016
Ivabradine: Do the Benefits Outweigh the Risks? Journal of cardiovascular pharmacology and therapeutics, 2017, Volume: 22, Issue:3 Topics: Angina Pectoris; Benzazepines; Bradycardia; Cardiovascular Agents; Heart Failure; Heart Rate; Humans; Ivabradine; Patient Safety; Recovery of Function; Risk Assessment; Risk Factors; Treatment Outcome; Ventricular Function, Left	2017
Funny channels in the control of cardiac rhythm and mode of action of selective blockers. Pharmacological research, 2006, Volume: 53, Issue:5 Topics: Animals; Autonomic Nervous System; Benzazepines; Bradycardia; Cell Transplantation; Cyclic Nucleotide-Gated Cation Channels; Depression, Chemical; Diastole; Genetic Therapy; Heart; Heart Block; Heart Rate; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channels; Ivabradine; Muscle Proteins; Point Mutation; Potassium Channels	2006
Novel If current inhibitor ivabradine: safety considerations. Advances in cardiology, 2006, Volume: 43 Topics: Adrenergic beta-Antagonists; Angina Pectoris; Automobile Driving; Benzazepines; Bradycardia; Cardiotonic Agents; Cardiovascular Diseases; Clinical Trials as Topic; Eye; Heart Conduction System; Heart Rate; Humans; Ion Channels; Ivabradine; Sinoatrial Node	2006
I f inhibition with ivabradine : electrophysiological effects and safety. Drug safety, 2008, Volume: 31, Issue:2 Topics: Animals; Benzazepines; Bradycardia; Cardiac Electrophysiology; Heart Rate; Humans; Ion Channels; Ivabradine; Sinoatrial Node	2008

Trials

5 trial(s) available for ivabradine and Bradyarrhythmia

Article	Year
Pharmacokinetic and safety profile of ivabradine in healthy Chinese men: a phase I, randomized, open-label, increasing single- and multiple-dose study. Clinical therapeutics, 2013, Volume: 35, Issue:12 Topics: Administration, Oral; Adolescent; Adult; Asian People; Benzazepines; Blood Pressure; Bradycardia; Dose-Response Relationship, Drug; Drug Administration Schedule; Electrocardiography, Ambulatory; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Young Adult	2013
Bradycardia and atrial fibrillation in patients with stable coronary artery disease treated with ivabradine: an analysis from the SIGNIFY study. European heart journal, 2015, Dec-07, Volume: 36, Issue:46 Topics: Aged; Atrial Fibrillation; Benzazepines; Bradycardia; Cardiovascular Agents; Coronary Artery Disease; Double-Blind Method; Female; Humans; Ivabradine; Male; Middle Aged; Risk Factors	2015
Preserved Autonomic Cardiovascular Regulation With Cardiac Pacemaker Inhibition: A Crossover Trial Using High-Fidelity Cardiovascular Phenotyping. Journal of the American Heart Association, 2016, Jan-13, Volume: 5, Issue:1 Topics: Adult; Autonomic Nervous System; Baroreflex; Benzazepines; Biological Clocks; Blood Pressure; Bradycardia; Cardiovascular Agents; Cross-Over Studies; Double-Blind Method; Electrocardiography; Germany; Healthy Volunteers; Heart Rate; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ivabradine; Male; Muscle Proteins; Muscle, Skeletal; Potassium Channels; Sinoatrial Node; Time Factors; Young Adult	2016
Ivabradine for the treatment of stable angina pectoris in octogenarians. Clinical research in cardiology : official journal of the German Cardiac Society, 2011, Volume: 100, Issue:2 Topics: Aged, 80 and over; Angina Pectoris; Benzazepines; Bradycardia; Comorbidity; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Incidence; Ivabradine; Male	2011
Incremental value and safety of oral ivabradine for heart rate reduction in computed tomography coronary angiography. International journal of cardiology, 2012, Apr-05, Volume: 156, Issue:1 Topics: Administration, Oral; Aged; Benzazepines; Bradycardia; Coronary Angiography; Coronary Artery Disease; Female; Heart Rate; Humans; Ivabradine; Male; Middle Aged; Prospective Studies; Tomography, X-Ray Computed	2012

Other Studies

25 other study(ies) available for ivabradine and Bradyarrhythmia

Article	Year
Bradycardic and proarrhythmic properties of sinus node inhibitors. Molecular pharmacology, 2006, Volume: 69, Issue:4 Topics: Animals; Arrhythmias, Cardiac; Benzazepines; Bradycardia; Cardiotonic Agents; Cloning, Molecular; Electrocardiography; Humans; Ivabradine; Mice; Mice, Inbred C57BL; Piperidines; Sinoatrial Node; Up-Regulation	2006
No evidence for pericardial restraint in the snapping turtle ( American journal of physiology. Regulatory, integrative and comparative physiology, 2022, 05-01, Volume: 322, Issue:5 Topics: Animals; Bradycardia; Heart Rate; Ivabradine; Pericardium; Turtles	2022
Ivabradine toxicity: a case report. Journal of medical case reports, 2022, Oct-24, Volume: 16, Issue:1 Topics: Adult; Benzazepines; Bradycardia; Female; Heart Rate; Humans; Ivabradine; Tachycardia, Sinus; Treatment Outcome	2022
Ivabradine-Induced Bradycardia is Accompanied by Reduced Stress-Related Anxiety. American journal of hypertension, 2023, 05-21, Volume: 36, Issue:6 Topics: Animals; Anxiety; Bradycardia; Heart Rate; Hypertension; Ivabradine; Mice; Quality of Life	2023
Synergy between Membrane Currents Prevents Severe Bradycardia in Mouse Sinoatrial Node Tissue. International journal of molecular sciences, 2023, Mar-17, Volume: 24, Issue:6 Topics: Action Potentials; Animals; Bradycardia; Calcium; Ivabradine; Mice; Mice, Inbred C57BL; Sinoatrial Node	2023
Time to benefit of heart rate reduction with ivabradine in patients with heart failure and reduced ejection fraction. European journal of heart failure, 2023, Volume: 25, Issue:8 Topics: Benzazepines; Bradycardia; Cardiovascular Agents; Heart Failure; Heart Failure, Systolic; Heart Rate; Humans; Ivabradine; Stroke Volume; Treatment Outcome	2023
Serum Ivabradine Associates With Heart Rate Reduction But Enteral Exposure Is Unpredictable in Post surgical JET. JACC. Clinical electrophysiology, 2023, Volume: 9, Issue:8 Pt 3 Topics: Bradycardia; Cardiovascular Agents; Heart Rate; Humans; Ivabradine; Tachycardia, Ectopic Junctional	2023
Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR/Cas9-based approach. Scientific reports, 2020, 07-16, Volume: 10, Issue:1 Topics: Animals; Animals, Genetically Modified; Bradycardia; Cardiovascular Agents; CRISPR-Cas Systems; Embryo, Nonmammalian; Genes, Reporter; Genome-Wide Association Study; Green Fluorescent Proteins; Heart Rate; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ivabradine; Meta-Analysis as Topic; Myocardial Contraction; Myocytes, Smooth Muscle; Optical Imaging; Pleckstrin Homology Domains; RGS Proteins; Zebrafish	2020
Ivabradine preserves dynamic sympathetic control of heart rate despite inducing significant bradycardia in rats. The journal of physiological sciences : JPS, 2019, Volume: 69, Issue:2 Topics: Animals; Blood Pressure; Bradycardia; Heart Rate; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ivabradine; Male; Metoprolol; Rats; Rats, Inbred WKY; Sympathetic Nervous System	2019
Dronedarone's inhibition of If current is the primary mechanism responsible for its bradycardic effect. Journal of cardiovascular electrophysiology, 2013, Volume: 24, Issue:8 Topics: Amiodarone; Analysis of Variance; Animals; Arterial Pressure; Benzazepines; Blood Pressure; Bradycardia; Diltiazem; Dronedarone; Isoproterenol; Ivabradine; Myocardial Contraction; Swine	2013
New evidence for coupled clock regulation of the normal automaticity of sinoatrial nodal pacemaker cells: bradycardic effects of ivabradine are linked to suppression of intracellular Ca²⁺ cycling. Journal of molecular and cellular cardiology, 2013, Volume: 62 Topics: Animals; Benzazepines; Bradycardia; Calcium; Indoles; Ivabradine; Models, Biological; Models, Theoretical; Rabbits; Sarcoplasmic Reticulum; Sinoatrial Node	2013
Case report of ivabradine intoxication. Journal of analytical toxicology, 2014, Volume: 38, Issue:4 Topics: Anti-Arrhythmia Agents; Benzazepines; Bradycardia; Drug Overdose; Humans; Hypotension; Ivabradine; Male; Middle Aged; Severity of Illness Index; Spectrometry, Mass, Electrospray Ionization	2014
Slow junctional rhythm, QTc prolongation and transient torsades de-pointes following combined use of Ivabradine, Diltiazem and Ranolazine. The Journal of the Association of Physicians of India, 2014, Volume: 62, Issue:5 Topics: Acetanilides; Aged, 80 and over; Angina, Unstable; Benzazepines; Bradycardia; Diltiazem; Drug Interactions; Drug Substitution; Drug Therapy, Combination; Electrocardiography; Female; Humans; Ivabradine; Long QT Syndrome; Piperazines; Ranolazine; Torsades de Pointes	2014
Ivabradine and AV conduction. International journal of cardiology, 2015, Feb-15, Volume: 181 Topics: Atrial Flutter; Benzazepines; Bradycardia; Cardiovascular Agents; Catheter Ablation; Cyclic Nucleotide-Gated Cation Channels; Electrocardiography, Ambulatory; Humans; Ivabradine; Male; Middle Aged	2015
hERG potassium channel blockade by the HCN channel inhibitor bradycardic agent ivabradine. Journal of the American Heart Association, 2015, Apr-24, Volume: 4, Issue:4 Topics: Animals; Benzazepines; Bradycardia; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; Heart; HEK293 Cells; Humans; Ivabradine; Male; Patch-Clamp Techniques; Potassium Channel Blockers	2015
[Ivabradine poisoning with suicide intention]. Medicina intensiva, 2015, Volume: 39, Issue:9 Topics: Adult; Antidotes; Benzazepines; Bradycardia; Calcium Gluconate; Combined Modality Therapy; Drug Overdose; Electrocardiography; Female; Humans; Ivabradine; Loperamide; Losartan; Norepinephrine; Pacemaker, Artificial; Poisoning; Spironolactone; Suicide, Attempted	2015
Supraventricular and ventricular arrhythmias. European heart journal, 2015, Dec-07, Volume: 36, Issue:46 Topics: Anticoagulants; Arrhythmogenic Right Ventricular Dysplasia; Atrial Fibrillation; Benzazepines; Bradycardia; Cardiovascular Agents; Heart Diseases; Hemorrhage; Humans; Ivabradine; Point-of-Care Systems	2015
Acute on Chronic Ivabradine Overdose: a Case Report. Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2016, Volume: 12, Issue:2 Topics: Adult; Anti-Arrhythmia Agents; Atropine; Benzazepines; Bradycardia; Combined Modality Therapy; Cyclic Nucleotide-Gated Cation Channels; Drug Overdose; Emergency Service, Hospital; Female; Humans; Ivabradine; Membrane Transport Modulators; Postural Orthostatic Tachycardia Syndrome; Suicide, Attempted; Treatment Outcome; Virginia	2016
Symptomatic Bradycardia and Heart Failure Triggered by Ivabradine in a Patient Receiving Antiretroviral Therapy. Revista espanola de cardiologia (English ed.), 2016, Volume: 69, Issue:5 Topics: Anti-HIV Agents; Atazanavir Sulfate; Benzazepines; Bradycardia; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Emtricitabine; Female; Heart Failure; HIV Infections; Humans; Ivabradine; Middle Aged; Ritonavir; Tenofovir	2016
About Bradycardia and Secondary Heart Failure Induced by Ivabradine in a Patient With HIV. Revista espanola de cardiologia (English ed.), 2016, Volume: 69, Issue:8 Topics: Benzazepines; Bradycardia; Cardiovascular Agents; Heart Failure; Heart Rate; HIV; HIV Infections; Humans; Ivabradine	2016
About Bradycardia and Secondary Heart Failure Induced by Ivabradine in a Patient With HIV. Response. Revista espanola de cardiologia (English ed.), 2016, Volume: 69, Issue:8 Topics: Benzazepines; Bradycardia; Cardiovascular Agents; Heart Failure; Heart Rate; HIV; HIV Infections; Humans; Ivabradine	2016
Ivabradine and metoprolol differentially affect cardiac glucose metabolism despite similar heart rate reduction in a mouse model of dyslipidemia. American journal of physiology. Heart and circulatory physiology, 2016, 10-01, Volume: 311, Issue:4 Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Benzazepines; Bradycardia; Cardiovascular Agents; Disease Models, Animal; Dyslipidemias; Echocardiography; Energy Metabolism; Female; Glucose; Glycolysis; Heart; Heart Rate; Hemodynamics; Ivabradine; Longitudinal Studies; Male; Metoprolol; Mice; Myocardium; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stroke Volume; Telemetry; Transcriptome	2016
Chronic heart rate reduction facilitates cardiomyocyte survival after myocardial infarction. Anatomical record (Hoboken, N.J. : 2007), 2010, Volume: 293, Issue:5 Topics: Animals; Anti-Arrhythmia Agents; Atenolol; Benzazepines; Bradycardia; Cell Survival; Cicatrix; Coronary Circulation; Diastole; Disease Models, Animal; Heart Rate; Ivabradine; Male; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Recovery of Function; Regeneration; Treatment Outcome	2010
Acute and chronic cardiac and regional haemodynamic effects of the novel bradycardic agent, S16257, in conscious rats. British journal of pharmacology, 1995, Volume: 115, Issue:4 Topics: Animals; Benzazepines; Blood Pressure; Bradycardia; Cardiac Output; Cardiotonic Agents; Coronary Circulation; Heart; Heart Conduction System; Heart Rate; Hemodynamics; Injections, Intravenous; Injections, Subcutaneous; Ivabradine; Male; Mesenteric Arteries; Random Allocation; Rats; Regional Blood Flow; Renal Circulation; Stroke Volume	1995
Inhibition of the pacemaker current: a bradycardic therapy for off-pump coronary operations. The Annals of thoracic surgery, 1998, Volume: 66, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Benzazepines; Bradycardia; Cardiac Output; Cardiac Volume; Cardioplegic Solutions; Cardiopulmonary Bypass; Cardiotonic Agents; Coronary Artery Bypass; Coronary Circulation; Diastole; Heart Arrest, Induced; Heart Rate; Ivabradine; Myocardial Contraction; Niacinamide; Nicorandil; Potassium; Potassium Channels; Propanolamines; Rabbits; Sinoatrial Node; Stereoisomerism; Ventricular Function, Left	1998