Page last updated: 2024-10-18

itaconic acid and Reperfusion Injury

itaconic acid has been researched along with Reperfusion Injury in 4 studies

itaconic acid : A dicarboxylic acid that is methacrylic acid in which one of the methyl hydrogens is substituted by a carboxylic acid group.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"However, the key mediators of reperfusion injury remain unclear, and therefore, there is considerable interest in therapeutically targeting metabolism and the cellular response to oxidative stress."1.56Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury. ( Cabrales, P; Cordes, T; Divakaruni, AS; Lucas, A; Metallo, CM; Murphy, AN, 2020)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Yi, Z1
Deng, M1
Scott, MJ1
Fu, G1
Loughran, PA1
Lei, Z1
Li, S1
Sun, P1
Yang, C1
Li, W1
Xu, H1
Huang, F1
Billiar, TR1
Cordes, T1
Lucas, A1
Divakaruni, AS1
Murphy, AN1
Cabrales, P1
Metallo, CM1
Beier, UH1
Hartung, EA1
Concors, S1
Hernandez, PT1
Wang, Z1
Perry, C1
Baur, JA1
Denburg, MR1
Hancock, WW1
Gade, TP1
Levine, MH1
Lampropoulou, V1
Sergushichev, A1
Bambouskova, M1
Nair, S1
Vincent, EE1
Loginicheva, E1
Cervantes-Barragan, L1
Ma, X1
Huang, SC1
Griss, T1
Weinheimer, CJ1
Khader, S1
Randolph, GJ1
Pearce, EJ1
Jones, RG1
Diwan, A1
Diamond, MS1
Artyomov, MN1

Other Studies

4 other studies available for itaconic acid and Reperfusion Injury

ArticleYear
Immune-Responsive Gene 1/Itaconate Activates Nuclear Factor Erythroid 2-Related Factor 2 in Hepatocytes to Protect Against Liver Ischemia-Reperfusion Injury.
    Hepatology (Baltimore, Md.), 2020, Volume: 72, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Carboxy-Lyases; Hepatocytes; Humans; Hydro-Lyases; Liver; Male; M

2020
Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury.
    Molecular metabolism, 2020, Volume: 32

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Male; Mice;

2020
Tissue metabolic profiling shows that saccharopine accumulates during renal ischemic-reperfusion injury, while kynurenine and itaconate accumulate in renal allograft rejection.
    Metabolomics : Official journal of the Metabolomic Society, 2020, 05-04, Volume: 16, Issue:5

    Topics: Animals; Disease Models, Animal; Female; Graft Rejection; Kidney; Kidney Transplantation; Kynurenine

2020
Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
    Cell metabolism, 2016, 07-12, Volume: 24, Issue:1

    Topics: Animals; Cell Respiration; Female; Inflammation; Lipopolysaccharides; Macrophage Activation; Macroph

2016