itaconic acid has been researched along with Reperfusion Injury in 4 studies
itaconic acid : A dicarboxylic acid that is methacrylic acid in which one of the methyl hydrogens is substituted by a carboxylic acid group.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
Excerpt | Relevance | Reference |
---|---|---|
"However, the key mediators of reperfusion injury remain unclear, and therefore, there is considerable interest in therapeutically targeting metabolism and the cellular response to oxidative stress." | 1.56 | Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury. ( Cabrales, P; Cordes, T; Divakaruni, AS; Lucas, A; Metallo, CM; Murphy, AN, 2020) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 3 (75.00) | 2.80 |
Authors | Studies |
---|---|
Yi, Z | 1 |
Deng, M | 1 |
Scott, MJ | 1 |
Fu, G | 1 |
Loughran, PA | 1 |
Lei, Z | 1 |
Li, S | 1 |
Sun, P | 1 |
Yang, C | 1 |
Li, W | 1 |
Xu, H | 1 |
Huang, F | 1 |
Billiar, TR | 1 |
Cordes, T | 1 |
Lucas, A | 1 |
Divakaruni, AS | 1 |
Murphy, AN | 1 |
Cabrales, P | 1 |
Metallo, CM | 1 |
Beier, UH | 1 |
Hartung, EA | 1 |
Concors, S | 1 |
Hernandez, PT | 1 |
Wang, Z | 1 |
Perry, C | 1 |
Baur, JA | 1 |
Denburg, MR | 1 |
Hancock, WW | 1 |
Gade, TP | 1 |
Levine, MH | 1 |
Lampropoulou, V | 1 |
Sergushichev, A | 1 |
Bambouskova, M | 1 |
Nair, S | 1 |
Vincent, EE | 1 |
Loginicheva, E | 1 |
Cervantes-Barragan, L | 1 |
Ma, X | 1 |
Huang, SC | 1 |
Griss, T | 1 |
Weinheimer, CJ | 1 |
Khader, S | 1 |
Randolph, GJ | 1 |
Pearce, EJ | 1 |
Jones, RG | 1 |
Diwan, A | 1 |
Diamond, MS | 1 |
Artyomov, MN | 1 |
4 other studies available for itaconic acid and Reperfusion Injury
Article | Year |
---|---|
Immune-Responsive Gene 1/Itaconate Activates Nuclear Factor Erythroid 2-Related Factor 2 in Hepatocytes to Protect Against Liver Ischemia-Reperfusion Injury.
Topics: Animals; Anti-Inflammatory Agents; Carboxy-Lyases; Hepatocytes; Humans; Hydro-Lyases; Liver; Male; M | 2020 |
Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Male; Mice; | 2020 |
Tissue metabolic profiling shows that saccharopine accumulates during renal ischemic-reperfusion injury, while kynurenine and itaconate accumulate in renal allograft rejection.
Topics: Animals; Disease Models, Animal; Female; Graft Rejection; Kidney; Kidney Transplantation; Kynurenine | 2020 |
Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
Topics: Animals; Cell Respiration; Female; Inflammation; Lipopolysaccharides; Macrophage Activation; Macroph | 2016 |