itaconic acid has been researched along with Reperfusion Injury in 4 studies
itaconic acid : A dicarboxylic acid that is methacrylic acid in which one of the methyl hydrogens is substituted by a carboxylic acid group.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, the key mediators of reperfusion injury remain unclear, and therefore, there is considerable interest in therapeutically targeting metabolism and the cellular response to oxidative stress." | 1.56 | Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury. ( Cabrales, P; Cordes, T; Divakaruni, AS; Lucas, A; Metallo, CM; Murphy, AN, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 3 (75.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yi, Z | 1 |
| Deng, M | 1 |
| Scott, MJ | 1 |
| Fu, G | 1 |
| Loughran, PA | 1 |
| Lei, Z | 1 |
| Li, S | 1 |
| Sun, P | 1 |
| Yang, C | 1 |
| Li, W | 1 |
| Xu, H | 1 |
| Huang, F | 1 |
| Billiar, TR | 1 |
| Cordes, T | 1 |
| Lucas, A | 1 |
| Divakaruni, AS | 1 |
| Murphy, AN | 1 |
| Cabrales, P | 1 |
| Metallo, CM | 1 |
| Beier, UH | 1 |
| Hartung, EA | 1 |
| Concors, S | 1 |
| Hernandez, PT | 1 |
| Wang, Z | 1 |
| Perry, C | 1 |
| Baur, JA | 1 |
| Denburg, MR | 1 |
| Hancock, WW | 1 |
| Gade, TP | 1 |
| Levine, MH | 1 |
| Lampropoulou, V | 1 |
| Sergushichev, A | 1 |
| Bambouskova, M | 1 |
| Nair, S | 1 |
| Vincent, EE | 1 |
| Loginicheva, E | 1 |
| Cervantes-Barragan, L | 1 |
| Ma, X | 1 |
| Huang, SC | 1 |
| Griss, T | 1 |
| Weinheimer, CJ | 1 |
| Khader, S | 1 |
| Randolph, GJ | 1 |
| Pearce, EJ | 1 |
| Jones, RG | 1 |
| Diwan, A | 1 |
| Diamond, MS | 1 |
| Artyomov, MN | 1 |
4 other studies available for itaconic acid and Reperfusion Injury
| Article | Year |
|---|---|
Immune-Responsive Gene 1/Itaconate Activates Nuclear Factor Erythroid 2-Related Factor 2 in Hepatocytes to Protect Against Liver Ischemia-Reperfusion Injury.
Topics: Animals; Anti-Inflammatory Agents; Carboxy-Lyases; Hepatocytes; Humans; Hydro-Lyases; Liver; Male; M | 2020 |
Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Male; Mice; | 2020 |
Tissue metabolic profiling shows that saccharopine accumulates during renal ischemic-reperfusion injury, while kynurenine and itaconate accumulate in renal allograft rejection.
Topics: Animals; Disease Models, Animal; Female; Graft Rejection; Kidney; Kidney Transplantation; Kynurenine | 2020 |
Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation.
Topics: Animals; Cell Respiration; Female; Inflammation; Lipopolysaccharides; Macrophage Activation; Macroph | 2016 |