itaconic acid has been researched along with MS (Multiple Sclerosis) in 1 studies
itaconic acid : A dicarboxylic acid that is methacrylic acid in which one of the methyl hydrogens is substituted by a carboxylic acid group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "DMF, an approved treatment of multiple sclerosis, as well as DMI, 4OI and MMF, inhibited NLRP3 activation in macrophages in response to lysophosphatidylcholine, which is used to induce demyelination, suggesting a possible mechanism for DMF in multiple sclerosis through NLRP3 inhibition." | 1.72 | Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages. ( Allan, SM; Brough, D; Green, JP; Hoyle, C; Lemarchand, E, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoyle, C | 1 |
| Green, JP | 1 |
| Allan, SM | 1 |
| Brough, D | 1 |
| Lemarchand, E | 1 |
1 other study available for itaconic acid and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages.
Topics: Animals; Caspase 1; Caspases; Fumarates; Humans; Inflammasomes; Interleukin-1beta; Lipopolysaccharid | 2022 |