Page last updated: 2024-10-18

itaconic acid and MS (Multiple Sclerosis)

itaconic acid has been researched along with MS (Multiple Sclerosis) in 1 studies

itaconic acid : A dicarboxylic acid that is methacrylic acid in which one of the methyl hydrogens is substituted by a carboxylic acid group.

Research Excerpts

ExcerptRelevanceReference
"DMF, an approved treatment of multiple sclerosis, as well as DMI, 4OI and MMF, inhibited NLRP3 activation in macrophages in response to lysophosphatidylcholine, which is used to induce demyelination, suggesting a possible mechanism for DMF in multiple sclerosis through NLRP3 inhibition."1.72Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages. ( Allan, SM; Brough, D; Green, JP; Hoyle, C; Lemarchand, E, 2022)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Hoyle, C1
Green, JP1
Allan, SM1
Brough, D1
Lemarchand, E1

Other Studies

1 other study available for itaconic acid and MS (Multiple Sclerosis)

ArticleYear
Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages.
    Immunology, 2022, Volume: 165, Issue:4

    Topics: Animals; Caspase 1; Caspases; Fumarates; Humans; Inflammasomes; Interleukin-1beta; Lipopolysaccharid

2022