Page last updated: 2024-10-18

itaconic acid and Idiopathic Parkinson Disease

itaconic acid has been researched along with Idiopathic Parkinson Disease in 2 studies

itaconic acid : A dicarboxylic acid that is methacrylic acid in which one of the methyl hydrogens is substituted by a carboxylic acid group.

Research Excerpts

ExcerptRelevanceReference
"Here we show that the Parkinson's disease-associated leucine-rich repeat kinase 2 (LRRK2) orchestrates this defence response by scaffolding a complex between RAB32 and aconitate decarboxylase 1, which synthesizes itaconate from mitochondrial precursors."1.91Parkinson's disease kinase LRRK2 coordinates a cell-intrinsic itaconate-dependent defence pathway against intracellular Salmonella. ( Chen, M; Galán, JE; Lara-Tejero, M; Lian, H; Liu, J; Park, D; Schueder, F, 2023)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (100.00)2.80

Authors

AuthorsStudies
Lian, H1
Park, D1
Chen, M1
Schueder, F1
Lara-Tejero, M1
Liu, J1
Galán, JE1
Xia, N1
Madore, V1
Albalakhi, A1
Lin, S1
Stimpson, T1
Xu, Y1
Schwarzschild, MA1
Bakshi, R1

Other Studies

2 other studies available for itaconic acid and Idiopathic Parkinson Disease

ArticleYear
Parkinson's disease kinase LRRK2 coordinates a cell-intrinsic itaconate-dependent defence pathway against intracellular Salmonella.
    Nature microbiology, 2023, Volume: 8, Issue:10

    Topics: Animals; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice; Parkinson Disease; Sal

2023
Microglia-dependent neuroprotective effects of 4-octyl itaconate against rotenone-and MPP+-induced neurotoxicity in Parkinson's disease.
    Scientific reports, 2023, 09-20, Volume: 13, Issue:1

    Topics: Animals; Mice; Microglia; Neuroprotective Agents; Neurotoxicity Syndromes; NF-E2-Related Factor 2; P

2023