istradefylline has been researched along with Infarction--Middle-Cerebral-Artery* in 1 studies
1 other study(ies) available for istradefylline and Infarction--Middle-Cerebral-Artery
Article | Year |
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Inactivation of endothelial adenosine A
Inactivation of the gene for adenosine A. Thromboembolic stroke was induced by embolic middle cerebral artery occlusion in mice. Post-stroke outcomes were determined with neurological deficit scoring, infarct volume, inflammatory marker expression, brain leukocyte infiltration, blood-brain barrier (BBB) leakage, and oedema assessment. Anti-inflammatory effects of silencing the gene for A. Thromboembolic stroke induced Adora2a expression in the brain. Mice globally deficient in Adora2a (Adora2a. Specific inactivation of endothelial A Topics: Adenosine A2 Receptor Antagonists; Animals; Brain; Endothelial Cells; Humans; Infarction, Middle Cerebral Artery; Mice, Inbred C57BL; Mice, Transgenic; Microvessels; Neuroprotection; NLR Family, Pyrin Domain-Containing 3 Protein; Purines; Receptor, Adenosine A2A; Stroke; THP-1 Cells; Thromboembolism | 2019 |