isradipine has been researched along with Stroke in 6 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Massive hypertensive crises relating to cerebrovascular accidents such as strokes or ruptured aneurysms, or cardiovascular dysfunction and toxicity, are an important cause of morbidity and mortality associated with cocaine or methamphetamine use." | 5.11 | Isradipine decreases the hemodynamic response of cocaine and methamphetamine results from two human laboratory studies: results from two human laboratory studies. ( Ait-Daoud, N; Johnson, BA; Roache, JD; Wallace, C; Wang, Y; Wells, LT, 2005) |
| " Dihydropyridine-class calcium channel antagonists, such as isradipine, show promise as therapeutic agents for preventing cocaine-induced cerebral ischemia." | 4.81 | Treatment advances for cocaine-induced ischemic stroke: focus on dihydropyridine-class calcium channel antagonists. ( Ait-Daoud, N; Devous, MD; Johnson, BA; Ruiz, P, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, J | 1 |
| Liu, J | 1 |
| Li, D | 1 |
| Zhang, C | 1 |
| Liu, M | 1 |
| Sooriyarachchi, MR | 1 |
| Whitehead, J | 1 |
| Matsushita, T | 1 |
| Bolland, K | 1 |
| Whitehead, A | 1 |
| Johnson, BA | 2 |
| Wells, LT | 1 |
| Roache, JD | 1 |
| Wallace, C | 1 |
| Ait-Daoud, N | 2 |
| Wang, Y | 1 |
| Reese, T | 2 |
| Pórszász, R | 2 |
| Baumann, D | 2 |
| Bochelen, D | 1 |
| Boumezbeur, F | 1 |
| McAllister, KH | 1 |
| Sauter, A | 2 |
| Bjelke, B | 1 |
| Rudin, M | 2 |
| Devous, MD | 1 |
| Ruiz, P | 1 |
| Rausch, M | 1 |
2 reviews available for isradipine and Stroke
| Article | Year |
|---|---|
Calcium antagonists for acute ischemic stroke.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Brain Ischemia; Calcium; Calcium Channel Blockers; Fe | 2019 |
Treatment advances for cocaine-induced ischemic stroke: focus on dihydropyridine-class calcium channel antagonists.
Topics: Brain Ischemia; Calcium Channel Blockers; Cocaine-Related Disorders; Dihydropyridines; Humans; Israd | 2001 |
1 trial available for isradipine and Stroke
| Article | Year |
|---|---|
Isradipine decreases the hemodynamic response of cocaine and methamphetamine results from two human laboratory studies: results from two human laboratory studies.
Topics: Adult; Amphetamine-Related Disorders; Blood Pressure; Calcium Channel Blockers; Cocaine; Cocaine-Rel | 2005 |
3 other studies available for isradipine and Stroke
| Article | Year |
|---|---|
Incorporating data received after a sequential trial has stopped into the final analysis: implementation and comparison of methods.
Topics: Biometry; Calcium Channel Blockers; Clinical Trials as Topic; Data Interpretation, Statistical; Erec | 2003 |
Cytoprotection does not preserve brain functionality in rats during the acute post-stroke phase despite evidence of non-infarction provided by MRI.
Topics: Adenosine Triphosphate; Animals; Blood Volume; Brain; Cerebral Infarction; Cerebrovascular Circulati | 2000 |
Recovery of function in cytoprotected cerebral cortex in rat stroke model assessed by functional MRI.
Topics: Animals; Calcium Channel Blockers; Cerebral Cortex; Cerebrovascular Circulation; Electric Stimulatio | 2002 |