Page last updated: 2024-10-29

isradipine and Stroke

isradipine has been researched along with Stroke in 6 studies

Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
"Massive hypertensive crises relating to cerebrovascular accidents such as strokes or ruptured aneurysms, or cardiovascular dysfunction and toxicity, are an important cause of morbidity and mortality associated with cocaine or methamphetamine use."5.11Isradipine decreases the hemodynamic response of cocaine and methamphetamine results from two human laboratory studies: results from two human laboratory studies. ( Ait-Daoud, N; Johnson, BA; Roache, JD; Wallace, C; Wang, Y; Wells, LT, 2005)
" Dihydropyridine-class calcium channel antagonists, such as isradipine, show promise as therapeutic agents for preventing cocaine-induced cerebral ischemia."4.81Treatment advances for cocaine-induced ischemic stroke: focus on dihydropyridine-class calcium channel antagonists. ( Ait-Daoud, N; Devous, MD; Johnson, BA; Ruiz, P, 2001)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, J1
Liu, J1
Li, D1
Zhang, C1
Liu, M1
Sooriyarachchi, MR1
Whitehead, J1
Matsushita, T1
Bolland, K1
Whitehead, A1
Johnson, BA2
Wells, LT1
Roache, JD1
Wallace, C1
Ait-Daoud, N2
Wang, Y1
Reese, T2
Pórszász, R2
Baumann, D2
Bochelen, D1
Boumezbeur, F1
McAllister, KH1
Sauter, A2
Bjelke, B1
Rudin, M2
Devous, MD1
Ruiz, P1
Rausch, M1

Reviews

2 reviews available for isradipine and Stroke

ArticleYear
Calcium antagonists for acute ischemic stroke.
    The Cochrane database of systematic reviews, 2019, 02-13, Volume: 2

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Brain Ischemia; Calcium; Calcium Channel Blockers; Fe

2019
Treatment advances for cocaine-induced ischemic stroke: focus on dihydropyridine-class calcium channel antagonists.
    The American journal of psychiatry, 2001, Volume: 158, Issue:8

    Topics: Brain Ischemia; Calcium Channel Blockers; Cocaine-Related Disorders; Dihydropyridines; Humans; Israd

2001

Trials

1 trial available for isradipine and Stroke

ArticleYear
Isradipine decreases the hemodynamic response of cocaine and methamphetamine results from two human laboratory studies: results from two human laboratory studies.
    American journal of hypertension, 2005, Volume: 18, Issue:6

    Topics: Adult; Amphetamine-Related Disorders; Blood Pressure; Calcium Channel Blockers; Cocaine; Cocaine-Rel

2005

Other Studies

3 other studies available for isradipine and Stroke

ArticleYear
Incorporating data received after a sequential trial has stopped into the final analysis: implementation and comparison of methods.
    Biometrics, 2003, Volume: 59, Issue:3

    Topics: Biometry; Calcium Channel Blockers; Clinical Trials as Topic; Data Interpretation, Statistical; Erec

2003
Cytoprotection does not preserve brain functionality in rats during the acute post-stroke phase despite evidence of non-infarction provided by MRI.
    NMR in biomedicine, 2000, Volume: 13, Issue:6

    Topics: Adenosine Triphosphate; Animals; Blood Volume; Brain; Cerebral Infarction; Cerebrovascular Circulati

2000
Recovery of function in cytoprotected cerebral cortex in rat stroke model assessed by functional MRI.
    Magnetic resonance in medicine, 2002, Volume: 47, Issue:4

    Topics: Animals; Calcium Channel Blockers; Cerebral Cortex; Cerebrovascular Circulation; Electric Stimulatio

2002