isradipine has been researched along with Pre-Eclampsia in 8 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the effects of isradipine or metoprolol on insulin sensitivity and lipid profiles as well as on blood pressure and umbilical vascular resistance in pre-eclamptic women in the third trimester of pregnancy." | 9.09 | Short-term metabolic effects of isradipine and metoprolol in pre-eclampsia. ( Cacciatore, B; Kaaja, RJ; Laakso, M; Laivuori, HM; Tikkanen, MJ; Ylikorkala, RO, 1999) |
| "Isradipine lowered the maternal mean arterial blood pressure effectively in women with nonproteinuric hypertension but did not do so in women with proteinuria at recruitment or appearing during treatment." | 9.08 | Calcium channel blockade (isradipine) in treatment of hypertension in pregnancy: a randomized placebo-controlled study. ( Andersson, KE; Forman, A; Ingemarsson, I; Lindberg, B; Lindeberg, S; Lunell, NO; Marsàl, K; Skajaa, K; Wide-Swensson, DH, 1995) |
| "To determine the haemostatic status in preeclampsia and to investigate the effects of short-term use of anti-hypertensive drugs, methyldopa and isradipine." | 6.69 | Preeclampsia: haemostatic status and the short-term effects of methyldopa and isradipine therapy. ( Arulkumaran, S; Biswas, A; Koh, SC; Malcus, P; Ratnam, SS; SvenMontan, S; Yin, KH, 1998) |
| "Provided that preeclampsia comprises enhanced vascular actions of thromboxane A2, the present results support the established use of Mg++ in the treatment of this condition and suggest that calcium antagonists are of potential benefit." | 5.28 | Effects of magnesium and isradipine on contractile activation induced by the thromboxane A2 analog U46619 in human uteroplacental arteries in term pregnancy. ( Andersson, KE; Forman, A; Skajaa, K; Svane, D, 1990) |
| "To study the effects of isradipine or metoprolol on insulin sensitivity and lipid profiles as well as on blood pressure and umbilical vascular resistance in pre-eclamptic women in the third trimester of pregnancy." | 5.09 | Short-term metabolic effects of isradipine and metoprolol in pre-eclampsia. ( Cacciatore, B; Kaaja, RJ; Laakso, M; Laivuori, HM; Tikkanen, MJ; Ylikorkala, RO, 1999) |
| "Isradipine lowered the maternal mean arterial blood pressure effectively in women with nonproteinuric hypertension but did not do so in women with proteinuria at recruitment or appearing during treatment." | 5.08 | Calcium channel blockade (isradipine) in treatment of hypertension in pregnancy: a randomized placebo-controlled study. ( Andersson, KE; Forman, A; Ingemarsson, I; Lindberg, B; Lindeberg, S; Lunell, NO; Marsàl, K; Skajaa, K; Wide-Swensson, DH, 1995) |
| "To determine the haemostatic status in preeclampsia and to investigate the effects of short-term use of anti-hypertensive drugs, methyldopa and isradipine." | 2.69 | Preeclampsia: haemostatic status and the short-term effects of methyldopa and isradipine therapy. ( Arulkumaran, S; Biswas, A; Koh, SC; Malcus, P; Ratnam, SS; SvenMontan, S; Yin, KH, 1998) |
| "Provided that preeclampsia comprises enhanced vascular actions of thromboxane A2, the present results support the established use of Mg++ in the treatment of this condition and suggest that calcium antagonists are of potential benefit." | 1.28 | Effects of magnesium and isradipine on contractile activation induced by the thromboxane A2 analog U46619 in human uteroplacental arteries in term pregnancy. ( Andersson, KE; Forman, A; Skajaa, K; Svane, D, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wide-Swensson, DH | 1 |
| Ingemarsson, I | 3 |
| Lunell, NO | 1 |
| Forman, A | 2 |
| Skajaa, K | 2 |
| Lindberg, B | 1 |
| Lindeberg, S | 1 |
| Marsàl, K | 1 |
| Andersson, KE | 2 |
| Wide-Swensson, D | 1 |
| Montan, S | 2 |
| Arulkumaran, S | 3 |
| Ratnam, SS | 2 |
| Anandakumar, C | 1 |
| Ratnam, S | 1 |
| Yin, KH | 1 |
| Koh, SC | 1 |
| Malcus, P | 1 |
| SvenMontan, S | 1 |
| Biswas, A | 1 |
| Kaya, T | 1 |
| Cetin, A | 1 |
| Cetin, M | 1 |
| Sarioglu, Y | 1 |
| Laivuori, HM | 1 |
| Laakso, M | 1 |
| Tikkanen, MJ | 1 |
| Cacciatore, B | 1 |
| Ylikorkala, RO | 1 |
| Kaaja, RJ | 1 |
| Svane, D | 1 |
| Feiks, A | 1 |
| Grünberger, W | 1 |
| Meisner, W | 1 |
5 trials available for isradipine and Pre-Eclampsia
| Article | Year |
|---|---|
Calcium channel blockade (isradipine) in treatment of hypertension in pregnancy: a randomized placebo-controlled study.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Hear | 1995 |
Effect of methyldopa and isradipine on fetal heart rate pattern assessed by computerized cardiotocography in human pregnancy.
Topics: Adolescent; Adult; Cardiotocography; Female; Heart Rate, Fetal; Humans; Isradipine; Methyldopa; Pre- | 1993 |
Randomised controlled trial of methyldopa and isradipine in preeclampsia--effects on uteroplacental and fetal hemodynamics.
Topics: Antihypertensive Agents; Blood Pressure; Female; Gestational Age; Heart Rate; Heart Rate, Fetal; Hum | 1996 |
Preeclampsia: haemostatic status and the short-term effects of methyldopa and isradipine therapy.
Topics: Antihypertensive Agents; Female; Hemostasis; Humans; Isradipine; Methyldopa; Pre-Eclampsia; Pregnanc | 1998 |
Short-term metabolic effects of isradipine and metoprolol in pre-eclampsia.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; F | 1999 |
3 other studies available for isradipine and Pre-Eclampsia
| Article | Year |
|---|---|
Effect of endothelin-1 on spontaneous contractions and effects of nimodipine and isradipine on endothelin-1-induced contractions in myometrial strips isolated from normal pregnant and preeclamptic women.
Topics: Calcium Channel Blockers; Dose-Response Relationship, Drug; Endothelin-1; Female; Humans; In Vitro T | 1998 |
Effects of magnesium and isradipine on contractile activation induced by the thromboxane A2 analog U46619 in human uteroplacental arteries in term pregnancy.
Topics: Antihypertensive Agents; Arteries; Calcium Channel Blockers; Digoxin; Female; Humans; Indomethacin; | 1990 |
[Isradipine in therapy of hypertensive pregnancy complications].
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Infant, Newborn; Israd | 1990 |