isradipine has been researched along with Pituitary Neoplasms in 5 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Maitotoxin (MTX) is a water-soluble polyether, isolated from the marine dinoflagellate Gambierdiscus toxicus, that stimulates hormone release and Ca2+ influx." | 1.28 | Maitotoxin induces a calcium-dependent membrane depolarization in GH4C1 pituitary cells via activation of type L voltage-dependent calcium channels. ( Ramsdell, JS; Van Dolah, FM; Xi, D, 1992) |
| "As the secretory activity of the pituitary adenomas, involving Ca2+ mobilization, varies from one adenoma to another, our results could indicate that, if there is a modified regulation of Ca2+ entry in the adenomas, it may not be related to a varying number of calcium channels, at least the channels labeled by the dihydropyridine (+)-PN 200-110." | 1.27 | Binding of (+)-PN 200-110 to rat pituitaries and to normal and adenomatous human pituitaries. ( Brandi, AM; Bression, D; Chaumet-Riffaud, P; Comte, A; Kiechel, JR; Peillon, F, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xi, D | 1 |
| Van Dolah, FM | 1 |
| Ramsdell, JS | 1 |
| Guérineau, N | 1 |
| Corcuff, JB | 1 |
| Tabarin, A | 1 |
| Mollard, P | 1 |
| Scherübl, H | 1 |
| Hescheler, J | 1 |
| Laverrière, JN | 1 |
| Richard, JL | 1 |
| Buisson, N | 1 |
| Martial, JA | 1 |
| Tixier-Vidal, A | 1 |
| Gourdji, D | 1 |
| Bression, D | 1 |
| Chaumet-Riffaud, P | 1 |
| Brandi, AM | 1 |
| Comte, A | 1 |
| Peillon, F | 1 |
| Kiechel, JR | 1 |
5 other studies available for isradipine and Pituitary Neoplasms
| Article | Year |
|---|---|
Maitotoxin induces a calcium-dependent membrane depolarization in GH4C1 pituitary cells via activation of type L voltage-dependent calcium channels.
Topics: Animals; Calcium; Calcium Channels; Cell Membrane; Choline; Dose-Response Relationship, Drug; Isradi | 1992 |
Spontaneous and corticotropin-releasing factor-induced cytosolic calcium transients in corticotrophs.
Topics: Action Potentials; Adenoma; Adrenocorticotropic Hormone; Animals; Calcium; Calcium Channel Blockers; | 1991 |
Steady-state currents through voltage-dependent, dihydropyridine-sensitive Ca2+ channels in GH3 pituitary cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
Thyroliberin and dihydropyridines modulate prolactin gene expression through interacting pathways in GH3 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
Binding of (+)-PN 200-110 to rat pituitaries and to normal and adenomatous human pituitaries.
Topics: Adenoma; Animals; Binding, Competitive; Brain; Calcium Channel Blockers; Calcium Channels; Female; H | 1987 |