isradipine has been researched along with Pheochromocytoma in 7 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
Excerpt | Relevance | Reference |
---|---|---|
"Sphingosine's effect was prevented by simultaneous exposure to phorbol 12,13-dibutyrate, a potent activator of protein kinase C." | 1.28 | Protein kinase C participates in up-regulation of dihydropyridine-sensitive calcium channels by ethanol. ( Messing, RO; Savidge, B; Sneade, AB, 1990) |
"When nitrendipine was applied, a small increase in calcium current occurred and this was followed by a decrease." | 1.27 | Dihydropyridine binding and calcium channel function in clonal rat adrenal medullary tumor cells. ( Brown, AM; Hamilton, SL; Hawkes, MJ; Kunze, DL, 1987) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (42.86) | 18.7374 |
1990's | 4 (57.14) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Gollasch, M | 1 |
Hescheler, J | 1 |
Spicher, K | 1 |
Klinz, FJ | 1 |
Schultz, G | 1 |
Rosenthal, W | 1 |
Januszewicz, W | 1 |
Wocial, B | 1 |
Chodakowska, J | 1 |
Feltynowski, T | 1 |
LapiĆski, M | 1 |
Messing, RO | 3 |
Sneade, AB | 1 |
Savidge, B | 1 |
Usowicz, MM | 1 |
Porzig, H | 1 |
Becker, C | 1 |
Reuter, H | 1 |
Kunze, DL | 1 |
Hamilton, SL | 1 |
Hawkes, MJ | 1 |
Brown, AM | 1 |
Marks, SS | 1 |
Watson, DL | 1 |
Carpenter, CL | 2 |
Greenberg, DA | 2 |
7 other studies available for isradipine and Pheochromocytoma
Article | Year |
---|---|
Inhibition of Ca2+ channels via alpha 2-adrenergic and muscarinic receptors in pheochromocytoma (PC-12) cells.
Topics: Adrenal Gland Neoplasms; Amino Acid Sequence; Animals; Atropine; Barium; Calcium Channel Blockers; C | 1991 |
Isradipine, catecholamines, and pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Blood Pressure; Calcium Channel Blockers; Catecholamines; Dihydropyr | 1991 |
Protein kinase C participates in up-regulation of dihydropyridine-sensitive calcium channels by ethanol.
Topics: Adrenal Gland Neoplasms; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; Ce | 1990 |
Differential expression by nerve growth factor of two types of Ca2+ channels in rat phaeochromocytoma cell lines.
Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels; Cell Di | 1990 |
Dihydropyridine binding and calcium channel function in clonal rat adrenal medullary tumor cells.
Topics: Adrenal Gland Neoplasms; Animals; Calcium; Cell Membrane; Clone Cells; Electrophysiology; Ion Channe | 1987 |
Comparative effects of chronic exposure to ethanol and calcium channel antagonists on calcium channel antagonist receptors in cultured neural (PC12) cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
Calcium channel antagonist properties of the antineoplastic antiestrogen tamoxifen in the PC12 neurosecretory cell line.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Division; Cell Line; Cell Survival; Isradipine; Oxa | 1987 |