isradipine has been researched along with Parkinsonian Disorders in 2 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Parkinson's disease is a common neurodegenerative disorder of unknown cause." | 2.44 | Calcium, ageing, and neuronal vulnerability in Parkinson's disease. ( Surmeier, DJ, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ilijic, E | 1 |
| Guzman, JN | 1 |
| Surmeier, DJ | 2 |
1 review available for isradipine and Parkinsonian Disorders
| Article | Year |
|---|---|
Calcium, ageing, and neuronal vulnerability in Parkinson's disease.
Topics: Aging; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Dopamine; Humans; Isradipine; N | 2007 |
1 other study available for isradipine and Parkinsonian Disorders
| Article | Year |
|---|---|
The L-type channel antagonist isradipine is neuroprotective in a mouse model of Parkinson's disease.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Disease Models, Anima | 2011 |