isradipine has been researched along with Nervous System Diseases in 3 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Nervous System Diseases: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
| Excerpt | Relevance | Reference |
|---|---|---|
| " An initial dose-response study using neurological deficit scores and estimates of protection from brain infarction (by histology) showed that isradipine reduced cortical infarctions compared to vehicle-treated animals at most doses (between 1." | 1.30 | Use of diffusion-weighted MRI and neurological deficit scores to demonstrate beneficial effects of isradipine in a rat model of focal ischemia. ( Barone, FC; Chandra, S; Coatney, RW; Everding, D; Feuerstein, GZ; Sarkar, SK; White, RF, 1999) |
| "The nifedipine response was reproduced by isradipine and by verapamil with IC50 values of 9 and 100 nM, respectively." | 1.28 | Various Ca2+ entry blockers prevent glutamate-induced neurotoxicity. ( Memo, M; Pizzi, M; Ribola, M; Spano, P; Valerio, A, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miyashita, Y | 1 |
| Peterson, D | 1 |
| Rees, JM | 1 |
| Flynn, JT | 1 |
| Chandra, S | 1 |
| White, RF | 1 |
| Everding, D | 1 |
| Feuerstein, GZ | 1 |
| Coatney, RW | 1 |
| Sarkar, SK | 1 |
| Barone, FC | 1 |
| Pizzi, M | 1 |
| Ribola, M | 1 |
| Valerio, A | 1 |
| Memo, M | 1 |
| Spano, P | 1 |
3 other studies available for isradipine and Nervous System Diseases
| Article | Year |
|---|---|
Isradipine for treatment of acute hypertension in hospitalized children and adolescents.
Topics: Acute Disease; Adolescent; Age Factors; Blood Pressure; Calcium Channel Blockers; Child; Child, Pres | 2010 |
Use of diffusion-weighted MRI and neurological deficit scores to demonstrate beneficial effects of isradipine in a rat model of focal ischemia.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Disease Models, Animal; Dose-Response Relationshi | 1999 |
Various Ca2+ entry blockers prevent glutamate-induced neurotoxicity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |