isradipine has been researched along with Necrosis in 2 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we investigated the potential beneficial effect of chronic treatment with a dual L-type Ca2+ and slow Na+ channel blockers isradipine, on the development of necrosis in myopathic hamster hearts." | 7.72 | Isradipine prevents the development of spontaneously occurring cardiac necrosis in cardiomyopathic hamster. ( Bkaily, G; Chahine, M; D'Orléans-Juste, P; Jacques, D; Jasmin, G, 2003) |
| " One dihydropyridine calcium antagonist (isradipine), given in doses which have been reported to ameliorate ischemic damage due to stroke, failed to reduce damage incurred by 30 min of hypoglycemic coma, or 15 min of transient forebrain ischemia." | 7.68 | The effect of a dihydropyridine calcium antagonist (isradipine) on selective neuronal necrosis. ( Ohta, S; Siesjö, BK; Smith, ML, 1991) |
| " In the present study, we investigated the potential beneficial effect of chronic treatment with a dual L-type Ca2+ and slow Na+ channel blockers isradipine, on the development of necrosis in myopathic hamster hearts." | 3.72 | Isradipine prevents the development of spontaneously occurring cardiac necrosis in cardiomyopathic hamster. ( Bkaily, G; Chahine, M; D'Orléans-Juste, P; Jacques, D; Jasmin, G, 2003) |
| " One dihydropyridine calcium antagonist (isradipine), given in doses which have been reported to ameliorate ischemic damage due to stroke, failed to reduce damage incurred by 30 min of hypoglycemic coma, or 15 min of transient forebrain ischemia." | 3.68 | The effect of a dihydropyridine calcium antagonist (isradipine) on selective neuronal necrosis. ( Ohta, S; Siesjö, BK; Smith, ML, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacques, D | 1 |
| Bkaily, G | 1 |
| Jasmin, G | 1 |
| D'Orléans-Juste, P | 1 |
| Chahine, M | 1 |
| Ohta, S | 1 |
| Smith, ML | 1 |
| Siesjö, BK | 1 |
2 other studies available for isradipine and Necrosis
| Article | Year |
|---|---|
Isradipine prevents the development of spontaneously occurring cardiac necrosis in cardiomyopathic hamster.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Cardiomyopathy, Dilated; Cricetinae; Is | 2003 |
The effect of a dihydropyridine calcium antagonist (isradipine) on selective neuronal necrosis.
Topics: Animals; Brain Diseases; Brain Ischemia; Calcium Channel Blockers; Coma; Hypoglycemia; Isradipine; M | 1991 |