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isradipine and Necrosis

isradipine has been researched along with Necrosis in 2 studies

Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
" In the present study, we investigated the potential beneficial effect of chronic treatment with a dual L-type Ca2+ and slow Na+ channel blockers isradipine, on the development of necrosis in myopathic hamster hearts."7.72Isradipine prevents the development of spontaneously occurring cardiac necrosis in cardiomyopathic hamster. ( Bkaily, G; Chahine, M; D'Orléans-Juste, P; Jacques, D; Jasmin, G, 2003)
" One dihydropyridine calcium antagonist (isradipine), given in doses which have been reported to ameliorate ischemic damage due to stroke, failed to reduce damage incurred by 30 min of hypoglycemic coma, or 15 min of transient forebrain ischemia."7.68The effect of a dihydropyridine calcium antagonist (isradipine) on selective neuronal necrosis. ( Ohta, S; Siesjö, BK; Smith, ML, 1991)
" In the present study, we investigated the potential beneficial effect of chronic treatment with a dual L-type Ca2+ and slow Na+ channel blockers isradipine, on the development of necrosis in myopathic hamster hearts."3.72Isradipine prevents the development of spontaneously occurring cardiac necrosis in cardiomyopathic hamster. ( Bkaily, G; Chahine, M; D'Orléans-Juste, P; Jacques, D; Jasmin, G, 2003)
" One dihydropyridine calcium antagonist (isradipine), given in doses which have been reported to ameliorate ischemic damage due to stroke, failed to reduce damage incurred by 30 min of hypoglycemic coma, or 15 min of transient forebrain ischemia."3.68The effect of a dihydropyridine calcium antagonist (isradipine) on selective neuronal necrosis. ( Ohta, S; Siesjö, BK; Smith, ML, 1991)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacques, D1
Bkaily, G1
Jasmin, G1
D'Orléans-Juste, P1
Chahine, M1
Ohta, S1
Smith, ML1
Siesjö, BK1

Other Studies

2 other studies available for isradipine and Necrosis

ArticleYear
Isradipine prevents the development of spontaneously occurring cardiac necrosis in cardiomyopathic hamster.
    Canadian journal of physiology and pharmacology, 2003, Volume: 81, Issue:2

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, T-Type; Cardiomyopathy, Dilated; Cricetinae; Is

2003
The effect of a dihydropyridine calcium antagonist (isradipine) on selective neuronal necrosis.
    Journal of the neurological sciences, 1991, Volume: 103, Issue:1

    Topics: Animals; Brain Diseases; Brain Ischemia; Calcium Channel Blockers; Coma; Hypoglycemia; Isradipine; M

1991