isradipine has been researched along with Muscle Relaxation in 12 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Continuous nitroglycerin (NTG) administration causes pharmacologic tolerance in humans and animals, whereas intermittent dosing is capable of avoiding or reducing tolerance development." | 5.29 | Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels. ( Bauer, JA; Fung, HL; Gopalakrishnan, M; Kwon, YW; Triggle, DJ; Zheng, W, 1993) |
| "The possible contribution of K+ channel activation to airway smooth muscle relaxation induced by vasoactive intestinal peptide (VIP) and atrial natriuretic peptide (ANP) was investigated in isolated guinea-pig trachea." | 3.69 | Involvement of K+ channels in the relaxant effect of vasoactive intestinal peptide and atrial natriuretic peptide in isolated guinea-pig trachea. ( Mellemkjaer, S; Nielsen-Kudsk, JE; Thirstrup, S, 1997) |
| "Continuous nitroglycerin (NTG) administration causes pharmacologic tolerance in humans and animals, whereas intermittent dosing is capable of avoiding or reducing tolerance development." | 1.29 | Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels. ( Bauer, JA; Fung, HL; Gopalakrishnan, M; Kwon, YW; Triggle, DJ; Zheng, W, 1993) |
| "Treatment with ramipril significantly improved maximum EDR to 53 +/- 3% (p < 0." | 1.29 | Comparison of the antiatherogenic effects of isradipine and ramipril in cholesterol-fed rabbits: I. Effect on progression of atherosclerosis and endothelial dysfunction. ( Beems, RB; de Wildt, DJ; Meijer, GW; Porsius, AJ; Riezebos, J; van Amsterdam, JG; Vleeming, W; Wemer, J, 1994) |
| "Isradipine treatment had no effect on vasoconstrictor responses to norepinephrine in vitro." | 1.28 | Effect of chronic treatment with the calcium entry blocker, isradipine, on vascular calcium overload produced by vitamin D3 and nicotine in rats. ( Atkinson, J; Capdeville-Atkinson, C; Chillon, JM; Henrion, D, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 11 (91.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bauer, JA | 1 |
| Fung, HL | 1 |
| Zheng, W | 1 |
| Kwon, YW | 1 |
| Gopalakrishnan, M | 1 |
| Triggle, DJ | 1 |
| Riezebos, J | 2 |
| Vleeming, W | 2 |
| Beems, RB | 2 |
| van Amsterdam, JG | 2 |
| Meijer, GW | 2 |
| de Wildt, DJ | 2 |
| Porsius, AJ | 2 |
| Wemer, J | 2 |
| Nakajima, M | 1 |
| Adachi, I | 1 |
| Ueda, M | 1 |
| Liu, JJ | 1 |
| Casley, D | 1 |
| Wojta, J | 1 |
| Gallicchio, M | 1 |
| Dauer, R | 1 |
| Johnston, CI | 1 |
| Buxton, BF | 1 |
| Akopov, SE | 1 |
| Salomone, S | 1 |
| Silva, CL | 1 |
| Morel, N | 1 |
| Godfraind, T | 1 |
| Thirstrup, S | 2 |
| Nielsen-Kudsk, JE | 1 |
| Mellemkjaer, S | 1 |
| Nielsen-Kudsk, F | 1 |
| Dahl, R | 1 |
| Henrion, D | 1 |
| Chillon, JM | 1 |
| Capdeville-Atkinson, C | 1 |
| Atkinson, J | 1 |
| Balkan, A | 1 |
| Uma, S | 1 |
| Ertan, M | 1 |
| Wiegrebe, W | 1 |
| Akbarali, HI | 1 |
| Bieger, D | 1 |
| Triggle, CR | 1 |
12 other studies available for isradipine and Muscle Relaxation
| Article | Year |
|---|---|
Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels.
Topics: Administration, Cutaneous; Animals; Aorta, Thoracic; Binding Sites; Drug Tolerance; Glyburide; Heart | 1993 |
Comparison of the antiatherogenic effects of isradipine and ramipril in cholesterol-fed rabbits: I. Effect on progression of atherosclerosis and endothelial dysfunction.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Cyclic AMP; Diet, Ath | 1994 |
Comparison of the antiatherogenic effects of isradipine and ramipril in cholesterol-fed rabbits: II. Effect on regression of atherosclerosis and restoration of endothelial function.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arteriosclerosis; Biomarkers; Cholesterol; Cholesterol, Die | 1994 |
Pharmacological studies on a new Dihydrothienopyridine calcium antagonist. 2nd communication: effects of S-(+)-methyl-4,7-dihydro-3-isobutyl-6-methyl-4- (3-nitrophenyl)thieno[2,3-b]pyridine-5-carboxylate on the 1,4-dihydropyridine binding sites in the bra
Topics: Animals; Binding, Competitive; Brain Chemistry; Calcium; Calcium Channel Blockers; Calcium Channels; | 1993 |
Effects of calcium- and ETA-receptor antagonists on endothelin-induced vasoconstriction and levels of endothelin in the human internal mammary artery.
Topics: Calcium Channel Blockers; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin Receptor Ant | 1994 |
Nitric oxide (EDRF) enhances the vasorelaxing effect of dihydropyridine calcium antagonists in isolated human middle cerebral arteries.
Topics: Adult; Arginine; Calcium Channel Blockers; Cerebral Arteries; Cyclooxygenase Inhibitors; Dihydropyri | 1996 |
Facilitation of the vasorelaxant action of calcium antagonists by basal nitric oxide in depolarized artery.
Topics: Animals; Aorta; Calcium; Cyclic GMP; In Vitro Techniques; Isradipine; Male; Muscle Relaxation; Muscl | 1996 |
Involvement of K+ channels in the relaxant effect of vasoactive intestinal peptide and atrial natriuretic peptide in isolated guinea-pig trachea.
Topics: Adenosine Triphosphate; Animals; Atrial Natriuretic Factor; Benzopyrans; Calcium Channel Blockers; C | 1997 |
In vitro studies on the interactions of beta2-adrenoceptor agonists, methylxanthines, Ca2+-channel blockers, K+-channel openers and other airway smooth muscle relaxants in isolated guinea-pig trachea.
Topics: Adrenergic beta-Agonists; Animals; Benzopyrans; Calcium Channel Blockers; Cromakalim; Drug Interacti | 1997 |
Effect of chronic treatment with the calcium entry blocker, isradipine, on vascular calcium overload produced by vitamin D3 and nicotine in rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Calcium; Calcium Channel Blockers; Cholecalci | 1992 |
Thiazolo[3,2-a]pyrimidine derivatives as calcium antagonists.
Topics: Animals; Calcium Channel Blockers; In Vitro Techniques; Isradipine; Magnetic Resonance Spectroscopy; | 1992 |
Inhibition of field stimulation-evoked relaxations in rat oesophageal smooth muscle by the calcium antagonist PN 200-110.
Topics: Animals; Calcium Channel Blockers; Dioxolanes; Electric Stimulation; Esophagus; In Vitro Techniques; | 1988 |