isradipine has been researched along with Left Ventricular Hypertrophy in 21 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to evaluate in 45 hypertensive patients with left ventricular hypertrophy (LVH) the effects of a 6-month course with one of three different antihypertensive regimens (the calcium channel blocker isradipine, the angiotensin converting enzyme inhibitor spirapril in monotherapy, or a combination of the two drugs, n = 15 per group) on blood pressure, LVH regression, and various functional correlates of LVH." | 9.08 | Comparison of spirapril, isradipine, or combination in hypertensive patients with left ventricular hypertrophy: effects on LVH regression and arrhythmogenic propensity. ( Beldekos, D; Bresnahan, M; Cokkinos, DV; Foussas, S; Gavras, H; Gavras, I; Handanis, S; Haralabidis, G; Hatzissavas, J; Manolis, AJ, 1998) |
| " Isradipine was used as first-line antihypertensive treatment in 15 patients who had mild-to-moderate hypertension and LVH, and who were studied before and after 6 months of treatment." | 9.07 | Regression of left ventricular hypertrophy with isradipine in previously untreated hypertensive patients. ( Antonopoulos, S; Athanasopoulos, G; Cokkinos, DV; Handanis, S; Kolovou, G; Manolis, AJ, 1993) |
| "The objective of this study was to analyze the long-term hemodynamic effects of the calcium antagonist isradipine in mild hypertension compared with those of the beta 1-selective adrenoceptor antagonist atenolol, focusing in particular on the development of cardiac hypertrophy." | 9.07 | Beneficial effect of isradipine on the development of left ventricular hypertrophy in mild hypertension. ( Gleerup, G; Haedersdal, C; Mehlsen, J; Winther, K, 1993) |
| "Isradipine is a dihydropyridine calcium antagonist used for the treatment of hypertension." | 8.78 | Cardiac effects of isradipine in patients with hypertension. ( Lund-Johansen, P, 1993) |
| " We attempted to verify the effectiveness of a new calcium antagonist, isradipine 5 mg SRO, on the reversal of left ventricular hypertrophy." | 7.69 | Evaluation of the effectiveness of isradipine SRO in the treatment of hypertensive patients with left ventricular hypertrophy. ( Baraldi, P; Masciocco, G; Mattioli, G; Modena, MG; Rossi, R, 1994) |
| "The purpose of this study was to ascertain if Isradipine treatment in spontaneously hypertensive rats (SHR) decreased hypertension-dependent left ventricular and coronary vascular hypertrophy." | 7.69 | Influence of isradipine treatment on left ventricular and coronary vascular hypertrophy in spontaneously hypertensive rats. ( Amenta, F; Ferrante, F, 1994) |
| "Left ventricular hypertrophy is a common clinical feature in hypertensive patients and may be associated with structural changes in vessel morphology." | 6.68 | Influence of isradipine and spirapril on left ventricular hypertrophy and resistance arteries. ( Heagerty, AM; Kenedi, P; Rietbrock, N; Stephens, N; Thürmann, PA; Weidinger, G, 1996) |
| "Patients with mild to moderate diastolic hypertension and LV mass in excess of 1 SD of normal values were randomized to isradipine (n = 89) or hydrochlorothiazide therapy (n = 45)." | 5.08 | Hydrochlorothiazide is superior to isradipine for reduction of left ventricular mass: results of a multicenter trial. The Isradipine Study Group. ( Chase, GA; Cushman, WG; Gottdiener, JS; Gottdiener, PS; Narayan, P; Papademetriou, V; Zachariah, PK, 1997) |
| "This study was designed to evaluate in 45 hypertensive patients with left ventricular hypertrophy (LVH) the effects of a 6-month course with one of three different antihypertensive regimens (the calcium channel blocker isradipine, the angiotensin converting enzyme inhibitor spirapril in monotherapy, or a combination of the two drugs, n = 15 per group) on blood pressure, LVH regression, and various functional correlates of LVH." | 5.08 | Comparison of spirapril, isradipine, or combination in hypertensive patients with left ventricular hypertrophy: effects on LVH regression and arrhythmogenic propensity. ( Beldekos, D; Bresnahan, M; Cokkinos, DV; Foussas, S; Gavras, H; Gavras, I; Handanis, S; Haralabidis, G; Hatzissavas, J; Manolis, AJ, 1998) |
| "The aim of the present study was to evaluate the effect of dihydropyridine calcium antagonist isradipine on left ventricular (LV) structure and function in patients with essential hypertension." | 5.07 | Reduction of left ventricular mass by short-term antihypertensive treatment with isradipine: a double-blind comparison with enalapril. ( Celentano, A; de Divitiis, O; Galderisi, M; Garofalo, M; Oliviero, M; Petrocelli, A; Tammaro, P, 1994) |
| " Isradipine was used as first-line antihypertensive treatment in 15 patients who had mild-to-moderate hypertension and LVH, and who were studied before and after 6 months of treatment." | 5.07 | Regression of left ventricular hypertrophy with isradipine in previously untreated hypertensive patients. ( Antonopoulos, S; Athanasopoulos, G; Cokkinos, DV; Handanis, S; Kolovou, G; Manolis, AJ, 1993) |
| "The objective of this study was to analyze the long-term hemodynamic effects of the calcium antagonist isradipine in mild hypertension compared with those of the beta 1-selective adrenoceptor antagonist atenolol, focusing in particular on the development of cardiac hypertrophy." | 5.07 | Beneficial effect of isradipine on the development of left ventricular hypertrophy in mild hypertension. ( Gleerup, G; Haedersdal, C; Mehlsen, J; Winther, K, 1993) |
| "Isradipine is a dihydropyridine calcium antagonist used for the treatment of hypertension." | 4.78 | Cardiac effects of isradipine in patients with hypertension. ( Lund-Johansen, P, 1993) |
| "The effect of regression of left ventricular hypertrophy was studied in deoxycorticosterone-acetate-salt hypertensive rats (DOCA-salt hypertensive rats) treated with tetrandrine." | 3.69 | Effects of tetrandrine on left ventricle hypertrophy in deoxycorticosterone acetate-salt hypertensive rats. ( Rao, MR; Xu, Y, 1995) |
| " We attempted to verify the effectiveness of a new calcium antagonist, isradipine 5 mg SRO, on the reversal of left ventricular hypertrophy." | 3.69 | Evaluation of the effectiveness of isradipine SRO in the treatment of hypertensive patients with left ventricular hypertrophy. ( Baraldi, P; Masciocco, G; Mattioli, G; Modena, MG; Rossi, R, 1994) |
| "The purpose of this study was to ascertain if Isradipine treatment in spontaneously hypertensive rats (SHR) decreased hypertension-dependent left ventricular and coronary vascular hypertrophy." | 3.69 | Influence of isradipine treatment on left ventricular and coronary vascular hypertrophy in spontaneously hypertensive rats. ( Amenta, F; Ferrante, F, 1994) |
| "Patients with severe left ventricular hypertrophy (left ventricular mass >360 g) had lower glomerular filtration fraction, greater renal vascular resistance, lower renal blood flow and increased microalbuminuria in comparison with patients with less pronounced cardiac changes." | 2.69 | Long-term renal and cardiovascular effects of antihypertensive treatment regimens based upon isradipine, perindopril and thiazide. ( Krusell, LR; Lederballe, O; Sihm, I; Thygesen, K, 2000) |
| "Untreated essential hypertension is associated with left ventricular hypertrophy (LVH) and structural changes in resistance vessels." | 2.68 | Normalization of structural cardiovascular changes during antihypertensive treatment with a regimen based on the ACE-inhibitor perindopril. ( Aalkjaer, C; Holm, M; Lederballe, O; Mulvany, M; Mørn, B; Schroeder, AP; Sihm, I; Thygesen, K, 1995) |
| "Left ventricular hypertrophy is a common clinical feature in hypertensive patients and may be associated with structural changes in vessel morphology." | 2.68 | Influence of isradipine and spirapril on left ventricular hypertrophy and resistance arteries. ( Heagerty, AM; Kenedi, P; Rietbrock, N; Stephens, N; Thürmann, PA; Weidinger, G, 1996) |
| "SHRs showed a significant left ventricular hypertrophy." | 1.29 | Effect of chronic dihydropyridine (isradipine) on the large arterial walls of spontaneously hypertensive rats. ( Duriez, M; Levy, BI; Michel, JB; Phillipe, M; Poitevin, P, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (85.71) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sihm, I | 3 |
| Schroeder, AP | 2 |
| Aalkjaer, C | 2 |
| Holm, M | 2 |
| Mørn, B | 2 |
| Mulvany, M | 2 |
| Thygesen, K | 3 |
| Lederballe, O | 2 |
| Xu, Y | 1 |
| Rao, MR | 1 |
| Galderisi, M | 1 |
| Celentano, A | 1 |
| Garofalo, M | 1 |
| Tammaro, P | 1 |
| Oliviero, M | 1 |
| Petrocelli, A | 1 |
| de Divitiis, O | 1 |
| Pedersen, OL | 1 |
| Levy, BI | 1 |
| Duriez, M | 1 |
| Phillipe, M | 1 |
| Poitevin, P | 1 |
| Michel, JB | 1 |
| Modena, MG | 1 |
| Masciocco, G | 1 |
| Rossi, R | 1 |
| Baraldi, P | 1 |
| Mattioli, G | 1 |
| Ferrante, F | 1 |
| Amenta, F | 1 |
| Lund-Johansen, P | 1 |
| Vyssoulis, GP | 1 |
| Karpanou, EA | 1 |
| Pitsavos, CE | 1 |
| Soulas, DK | 1 |
| Toutouzas, PK | 1 |
| Saragoça, MA | 1 |
| Cassiolatto, JL | 1 |
| Vanetta, AM | 1 |
| Canziani, ME | 1 |
| Abreu, P | 1 |
| Ventura, RT | 1 |
| Ramos, OL | 1 |
| Manolis, AJ | 2 |
| Kolovou, G | 1 |
| Handanis, S | 2 |
| Athanasopoulos, G | 1 |
| Antonopoulos, S | 1 |
| Cokkinos, DV | 2 |
| Mehlsen, J | 1 |
| Gleerup, G | 1 |
| Haedersdal, C | 1 |
| Winther, K | 1 |
| Grandi, AM | 1 |
| Bignotti, M | 1 |
| Gaudio, G | 1 |
| Zanzi, P | 1 |
| Guasti, L | 1 |
| Venco, A | 1 |
| Thürmann, PA | 1 |
| Stephens, N | 1 |
| Heagerty, AM | 1 |
| Kenedi, P | 1 |
| Weidinger, G | 1 |
| Rietbrock, N | 1 |
| Albrecht, T | 1 |
| Dulce, MC | 1 |
| Dulce, KK | 1 |
| Gotzen, R | 1 |
| Wolf, KJ | 1 |
| Papademetriou, V | 1 |
| Gottdiener, JS | 1 |
| Narayan, P | 1 |
| Cushman, WG | 1 |
| Zachariah, PK | 1 |
| Gottdiener, PS | 1 |
| Chase, GA | 1 |
| Beldekos, D | 1 |
| Haralabidis, G | 1 |
| Hatzissavas, J | 1 |
| Foussas, S | 1 |
| Bresnahan, M | 1 |
| Gavras, I | 1 |
| Gavras, H | 1 |
| Strauer, BE | 1 |
| Schwartzkopff, B | 1 |
| De Rosa, ML | 1 |
| Maddaluno, G | 1 |
| Lionetti, F | 1 |
| Di Palma, U | 1 |
| Albanese, L | 1 |
| Cardace, P | 1 |
| Baiano, A | 1 |
| Vigorito, C | 1 |
| Milnes, JT | 1 |
| MacLeod, KT | 1 |
| Krusell, LR | 1 |
1 review available for isradipine and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Cardiac effects of isradipine in patients with hypertension.
Topics: Coronary Artery Bypass; Heart; Heart Failure; Hemodynamics; Humans; Hypertension; Hypertrophy, Left | 1993 |
13 trials available for isradipine and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Normalization of structural cardiovascular changes during antihypertensive treatment with a regimen based on the ACE-inhibitor perindopril.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteries; Drug Therapy, Co | 1995 |
Reduction of left ventricular mass by short-term antihypertensive treatment with isradipine: a double-blind comparison with enalapril.
Topics: Antihypertensive Agents; Blood Pressure; Double-Blind Method; Echocardiography, Doppler; Enalapril; | 1994 |
Normalization of resistance artery structure and left ventricular morphology with a perindopril-based regimen.
Topics: Antihypertensive Agents; Arteries; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Left | 1994 |
Regression of left ventricular hypertrophy with isradipine antihypertensive therapy.
Topics: Aged; Echocardiography; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricula | 1993 |
Reversal of left ventricular hypertrophy with isradipine induces diminution of cardiac arrhythmias.
Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left | 1993 |
Regression of left ventricular hypertrophy with isradipine in previously untreated hypertensive patients.
Topics: Adult; Echocardiography, Doppler; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left | 1993 |
Beneficial effect of isradipine on the development of left ventricular hypertrophy in mild hypertension.
Topics: Aged; Atenolol; Blood Pressure; Double-Blind Method; Exercise Tolerance; Heart Rate; Heart Ventricle | 1993 |
Ambulatory blood pressure and left ventricular changes during antihypertensive treatment: perindopril versus isradipine.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Ch | 1995 |
Influence of isradipine and spirapril on left ventricular hypertrophy and resistance arteries.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteries; Blood Pressure; Drug Co | 1996 |
Hydrochlorothiazide is superior to isradipine for reduction of left ventricular mass: results of a multicenter trial. The Isradipine Study Group.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Double-Blind Method; E | 1997 |
Comparison of spirapril, isradipine, or combination in hypertensive patients with left ventricular hypertrophy: effects on LVH regression and arrhythmogenic propensity.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Press | 1998 |
Effects of enalapril and isradipine alone and in combination on blood pressure, renal function and echocardiographic parameters in mild hypertension.
Topics: Analysis of Variance; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Double-Blind Meth | 2000 |
Long-term renal and cardiovascular effects of antihypertensive treatment regimens based upon isradipine, perindopril and thiazide.
Topics: Adult; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Creatine; Diuretics; Follow-Up St | 2000 |
7 other studies available for isradipine and Left Ventricular Hypertrophy
| Article | Year |
|---|---|
Effects of tetrandrine on left ventricle hypertrophy in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Alkaloids; Animals; Antihypertensive Agents; Benzylisoquinolines; Binding, Competitive; Blood Pressu | 1995 |
Effect of chronic dihydropyridine (isradipine) on the large arterial walls of spontaneously hypertensive rats.
Topics: Animals; Aorta; Biomechanical Phenomena; Carotid Arteries; Collagen; Compliance; Elastin; Hemodynami | 1994 |
Evaluation of the effectiveness of isradipine SRO in the treatment of hypertensive patients with left ventricular hypertrophy.
Topics: Aged; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Isradipine; Mal | 1994 |
Influence of isradipine treatment on left ventricular and coronary vascular hypertrophy in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Coronary Vessels; Hypertension; Hypertrophy; Hypertrophy, Left Ventricular; | 1994 |
Hypertensive heart disease: quantitative evaluation of response to therapy with cine MR imaging.
Topics: Adult; Analysis of Variance; Antihypertensive Agents; Cardiac Volume; Evaluation Studies as Topic; F | 1997 |
Objectives of high blood pressure treatment: left ventricular hypertrophy, diastolic function, and coronary reserve.
Topics: Antihypertensive Agents; Arterioles; Bisoprolol; Blood Pressure; Coronary Circulation; Diastole; Dil | 1998 |
Reduced ryanodine receptor to dihydropyridine receptor ratio may underlie slowed contraction in a rabbit model of left ventricular cardiac hypertrophy.
Topics: Animals; Antihypertensive Agents; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cells | 2001 |