isradipine has been researched along with Lambert-Eaton Myasthenic Syndrome in 2 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Lambert-Eaton Myasthenic Syndrome: An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| el Far, O | 1 |
| Marquèze, B | 1 |
| Leveque, C | 1 |
| Martin-Moutôt, N | 2 |
| Lang, B | 1 |
| Newsom-Davis, J | 1 |
| Yoshida, A | 1 |
| Takahashi, M | 1 |
| Seagar, MJ | 1 |
| Arsac, C | 1 |
| Raymond, C | 1 |
| Dargent, B | 1 |
| Couraud, F | 1 |
| Pouget, J | 1 |
| Seagar, M | 1 |
2 other studies available for isradipine and Lambert-Eaton Myasthenic Syndrome
| Article | Year |
|---|---|
Antigens associated with N- and L-type calcium channels in Lambert-Eaton myasthenic syndrome.
Topics: Animals; Autoantibodies; Autoantigens; Brain; Calcium Channels; Calcium Channels, L-Type; Immunoglob | 1995 |
Immunoassays fail to detect antibodies against neuronal calcium channels in amyotrophic lateral sclerosis serum.
Topics: Amyotrophic Lateral Sclerosis; Animals; Autoantibodies; Brain; Calcium Channel Blockers; Calcium Cha | 1996 |