isradipine has been researched along with Kidney Failure, Chronic in 7 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Similar results were obtained when spirapril was combined with 5 mg isradipine in the initial and final single dose, or in the 3 months' treatment (5 mg o." | 6.69 | Acute and chronic effects of spirapril, alone or in combination with isradipine on kidney function and blood pressure in patients with reduced kidney function and hypertension. ( Boner, G; Erman, A; Rosenfeld, J; Shohat, J; Wittenberg, C, 1999) |
| "In a double-blind, randomized trial with 26 male white patients with essential hypertension in World Health Organization Stages I and II, we examined the impact of calcium entry blockade (5 to 10 mg/day isradipine, N = 14) and beta-blockade (100 to 200 mg/day metoprolol, N = 12) on early markers of hypertensive nephropathy before and after 7 weeks' treatment." | 5.07 | Impact of antihypertensive therapy with isradipine and metoprolol on early markers of hypertensive nephropathy. ( Rockstroh, J; Rüddel, H; Schächinger, H; Schlebusch, H; Schmieder, RE; Schulte, W, 1992) |
| "Sixty patients with chronic renal failure and hypertension were enrolled in the study." | 2.70 | A randomized and double-blind comparison of isradipine and spirapril as monotherapy and in combination on the decline in renal function in patients with chronic renal failure and hypertension. ( Jensen, HA; Ladefoged, SD; Mehlsen, J; Møller, ML; Petersen, JR; Petersen, LJ; Talleruphuus, U, 2001) |
| " Similar results were obtained when spirapril was combined with 5 mg isradipine in the initial and final single dose, or in the 3 months' treatment (5 mg o." | 2.69 | Acute and chronic effects of spirapril, alone or in combination with isradipine on kidney function and blood pressure in patients with reduced kidney function and hypertension. ( Boner, G; Erman, A; Rosenfeld, J; Shohat, J; Wittenberg, C, 1999) |
| "Both isradipine treatments were equally effective in reducing the mean 24-h BP levels." | 2.68 | Time-dependent effect of isradipine on the nocturnal hypertension in chronic renal failure. ( degli Uberti, EC; Fersini, C; Manfredini, R; Portaluppi, F; Vergnani, L, 1995) |
| " Considering the interpatient variability in isradipine disposition and the lack of significant differences in CLo between groups, no clear-cut dosing regimen alterations, based on single-dose data, are warranted in renal impairment." | 1.27 | The effects of renal function on the disposition of isradipine. ( Blouin, RA; Chandler, MH; Cutler, RE; Gonasun, LM; Schran, HF; Smith, AJ, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Portaluppi, F | 1 |
| Vergnani, L | 1 |
| Manfredini, R | 1 |
| degli Uberti, EC | 1 |
| Fersini, C | 1 |
| Wittenberg, C | 2 |
| Erman, A | 2 |
| Shohat, J | 2 |
| Boner, G | 2 |
| Rosenfeld, J | 1 |
| Petersen, LJ | 1 |
| Petersen, JR | 1 |
| Talleruphuus, U | 1 |
| Møller, ML | 1 |
| Ladefoged, SD | 1 |
| Mehlsen, J | 1 |
| Jensen, HA | 1 |
| Francischetti, EA | 1 |
| Schmieder, RE | 1 |
| Rüddel, H | 1 |
| Schlebusch, H | 1 |
| Rockstroh, J | 1 |
| Schächinger, H | 1 |
| Schulte, W | 1 |
| Chandler, MH | 1 |
| Schran, HF | 1 |
| Cutler, RE | 1 |
| Smith, AJ | 1 |
| Gonasun, LM | 1 |
| Blouin, RA | 1 |
1 review available for isradipine and Kidney Failure, Chronic
| Article | Year |
|---|---|
[Prevention of hypertensive nephropathy: what more besides arterial blood pressure control?].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Humans; Hypertens | 1992 |
5 trials available for isradipine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Time-dependent effect of isradipine on the nocturnal hypertension in chronic renal failure.
Topics: Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Delayed-Action Prepar | 1995 |
Concomitant administration of isradipine and spirapril prevents reduction of renal function induced by acute administration of spirapril in patients with reduced renal function.
Topics: Angiotensin-Converting Enzyme Inhibitors; Drug Combinations; Enalapril; Humans; Isradipine; Kidney; | 1994 |
Acute and chronic effects of spirapril, alone or in combination with isradipine on kidney function and blood pressure in patients with reduced kidney function and hypertension.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug | 1999 |
A randomized and double-blind comparison of isradipine and spirapril as monotherapy and in combination on the decline in renal function in patients with chronic renal failure and hypertension.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel B | 2001 |
Impact of antihypertensive therapy with isradipine and metoprolol on early markers of hypertensive nephropathy.
Topics: Antihypertensive Agents; Dihydropyridines; Double-Blind Method; Humans; Hypertension; Isradipine; Ki | 1992 |
1 other study available for isradipine and Kidney Failure, Chronic
| Article | Year |
|---|---|
The effects of renal function on the disposition of isradipine.
Topics: Adult; Aged; Calcium Channel Blockers; Female; Humans; Isradipine; Kidney Failure, Chronic; Male; Mi | 1988 |