isradipine has been researched along with Hypercholesterolemia in 8 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Hypercholesterolemia: A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.
| Excerpt | Relevance | Reference |
|---|---|---|
| " With the monotherapy of essential hypertension concurrent with hypercholesterolemia with the alpha 1-adrenoblocker Doxazosin, in addition to the agent's high antihypertensive effects, the authors noted its favourable action on lipid spectral parameters and platelet functional activity." | 3.69 | [Hypertension, diabetes mellitus, atherosclerosis: clinical manifestations of metabolic syndrome X. Prospects of pharmacological treatment]. ( Ivleva, AIa; Kobalava, ZhD; Moiseev, VS, 1995) |
| "108 male rabbits, aged 6 months, with experimental hypercholesterolemia and experimental abdominal aortic lesioning received different regimen of antiatherosclerotic treatment; 36 of them were treated with isradipine, a dihydropyridine calcium antagonist (0." | 3.68 | Concomitant aspirin treatment abolishes the antiatherosclerotic effects of the calcium channel blocker isradipine mediated by PGI2. ( Angelberger, P; Gerakakis, A; Keiler, A; Lupattelli, G; Pirich, C; Sinzinger, H; Virgolini, I, 1992) |
| "In isradipine-treated groups I/M ratios were significantly decreased (0." | 1.30 | Direct antiatherogenic activity of isradipine and lacidipine on neointimal lesions induced by perivascular manipulation in rabbits. ( Donetti, E; Fumagalli, R; Paoletti, R; Soma, MR, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (87.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moiseev, VS | 1 |
| Ivleva, AIa | 1 |
| Kobalava, ZhD | 1 |
| Iurina, NA | 1 |
| Sorokovoĭ, VI | 1 |
| Romashova, MF | 1 |
| Mochenova, NN | 1 |
| Schmid, P | 1 |
| Pirich, C | 2 |
| Fitscha, P | 3 |
| Pesau, B | 1 |
| Virgolini, I | 3 |
| Sinzinger, H | 4 |
| Lupattelli, G | 3 |
| Kritz, H | 1 |
| O'Grady, J | 1 |
| Donetti, E | 1 |
| Fumagalli, R | 1 |
| Paoletti, R | 1 |
| Soma, MR | 1 |
| Bracht, C | 1 |
| Yan, XW | 1 |
| Brunner-LaRocca, HP | 1 |
| Sütsch, G | 1 |
| Amann, FW | 1 |
| Kiowski, W | 1 |
| Keiler, A | 1 |
| Gerakakis, A | 2 |
| Angelberger, P | 2 |
| Molinari, E | 1 |
2 trials available for isradipine and Hypercholesterolemia
| Article | Year |
|---|---|
Isradipine increases platelet--low-density lipoprotein binding: evidence from ex-vivo studies in humans.
Topics: Adult; Aged; Blood Platelets; Female; Hemodynamics; Humans; Hypercholesterolemia; Hypertension; Isra | 1994 |
Isradipine improves endothelium-dependent vasodilation in normotensive coronary artery disease patients with hypercholesterolemia.
Topics: Aged; Blood Pressure; Cholesterol; Coronary Disease; Double-Blind Method; Endothelium, Vascular; For | 2001 |
6 other studies available for isradipine and Hypercholesterolemia
| Article | Year |
|---|---|
[Hypertension, diabetes mellitus, atherosclerosis: clinical manifestations of metabolic syndrome X. Prospects of pharmacological treatment].
Topics: Anticholesteremic Agents; Arteriosclerosis; Diabetes Mellitus; Diabetes Mellitus, Type 2; Doxazosin; | 1995 |
[The effect of eicosapentaenoic acid and the calcium antagonist isradipin on lipid metabolism and erythrocytes in experimental hypercholesterolemia in rabbits].
Topics: Animals; Cholesterol; Eicosapentaenoic Acid; Erythrocytes; Fatty Acids, Nonesterified; Hypercholeste | 1993 |
Prostaglandin I2-mediated upregulation of 125I-LDL-receptor binding by isradipine in normo- and hypercholesterolemic rabbits in vivo.
Topics: Animals; Calcium Channel Blockers; Cohort Studies; Epoprostenol; Humans; Hypercholesterolemia; Iodin | 1996 |
Direct antiatherogenic activity of isradipine and lacidipine on neointimal lesions induced by perivascular manipulation in rabbits.
Topics: Animals; Arteriosclerosis; Calcium Channel Blockers; Carotid Arteries; Dihydropyridines; Dose-Respon | 1997 |
Concomitant aspirin treatment abolishes the antiatherosclerotic effects of the calcium channel blocker isradipine mediated by PGI2.
Topics: Animals; Aorta, Abdominal; Arteriosclerosis; Aspirin; Calcium Channel Blockers; Cholesterol; Dihydro | 1992 |
Isradipine, a calcium-entry blocker, decreases vascular [125-I]low-density lipoprotein entry in hypercholesterolemic rabbits.
Topics: Animals; Aorta, Thoracic; Blood Vessels; Calcium Channel Blockers; Epoprostenol; Hypercholesterolemi | 1991 |