isradipine has been researched along with Heart Disease, Ischemic in 12 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Isradipine is a dihydropyridine calcium antagonist used for the treatment of hypertension." | 8.78 | Cardiac effects of isradipine in patients with hypertension. ( Lund-Johansen, P, 1993) |
| "The present results provide indirect support for other studies which showed that halothane inhibited the Ca2+ accumulation associated with myocardial ischemia in isolated guinea pig hearts (6), demonstrating a potentially beneficial effect of the anesthetic on the ischemic heart." | 7.69 | Effect of halothane on sarcolemmal calcium channels during myocardial ischemia and reperfusion. ( Drenger, B; Ginosar, Y; Gozal, Y, 1994) |
| "To compare the negative inotropic effects of the four dihydropyridine-calcium-channel-blockers nifedipine (NIF), isradipine (ISR), nisoldipine (NIS) and felodipine (FEL) in man, the drugs were infused within 30 min intravenously in an equihypotensive dosage (NIF 2 mg, ISR 0." | 6.67 | [Comparison of the cardiodepressive effects of nifedipine, isradipine, nisoldipine and felodipine in patients with coronary heart disease]. ( Ickrath, O; Karsch, KR; Mauser, M; Voelker, W, 1993) |
| "Isradipine is a dihydropyridine calcium antagonist used for the treatment of hypertension." | 4.78 | Cardiac effects of isradipine in patients with hypertension. ( Lund-Johansen, P, 1993) |
| "The present results provide indirect support for other studies which showed that halothane inhibited the Ca2+ accumulation associated with myocardial ischemia in isolated guinea pig hearts (6), demonstrating a potentially beneficial effect of the anesthetic on the ischemic heart." | 3.69 | Effect of halothane on sarcolemmal calcium channels during myocardial ischemia and reperfusion. ( Drenger, B; Ginosar, Y; Gozal, Y, 1994) |
| "To compare the negative inotropic effects of the four dihydropyridine-calcium-channel-blockers nifedipine (NIF), isradipine (ISR), nisoldipine (NIS) and felodipine (FEL) in man, the drugs were infused within 30 min intravenously in an equihypotensive dosage (NIF 2 mg, ISR 0." | 2.67 | [Comparison of the cardiodepressive effects of nifedipine, isradipine, nisoldipine and felodipine in patients with coronary heart disease]. ( Ickrath, O; Karsch, KR; Mauser, M; Voelker, W, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (91.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shangina, OA | 1 |
| Kostin, VI | 1 |
| Koturga, LI | 1 |
| Wout van den Toren, E | 1 |
| de Vries, RJ | 1 |
| Portegies, MC | 1 |
| Blanksma, PK | 1 |
| van Gilst, WH | 1 |
| Hillege, HJ | 1 |
| van Veldhuisen, DJ | 1 |
| Lie, KI | 1 |
| Blanck, TJ | 2 |
| Gardner, TJ | 2 |
| Drenger, B | 2 |
| Ginosar, Y | 2 |
| Gozal, Y | 2 |
| Stokke, M | 2 |
| Aksnes, G | 1 |
| Lande, K | 1 |
| Hagelin, EM | 2 |
| Brørs, O | 2 |
| Chandra, M | 1 |
| Reches, A | 1 |
| Lund-Johansen, P | 1 |
| Mauser, M | 1 |
| Voelker, W | 1 |
| Ickrath, O | 1 |
| Karsch, KR | 1 |
| Zucchi, R | 1 |
| Ronca-Testoni, S | 1 |
| Yu, G | 1 |
| Galbani, P | 1 |
| Ronca, G | 1 |
| Mariani, M | 1 |
| Kirkebøen, KA | 1 |
| Naess, PA | 1 |
| Ilebekk, A | 1 |
| Yasukochi, S | 1 |
| Quigg, M | 1 |
| Curtis, WE | 1 |
| Burger, W | 1 |
| Fuchs, S | 1 |
| Burger, KJ | 1 |
| Kober, G | 1 |
1 review available for isradipine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Cardiac effects of isradipine in patients with hypertension.
Topics: Coronary Artery Bypass; Heart; Heart Failure; Hemodynamics; Humans; Hypertension; Hypertrophy, Left | 1993 |
3 trials available for isradipine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Effect of isradipine and nifedipine on diastolic function in patients with left ventricular dysfunction due to coronary artery disease: a randomized, double-blind, nuclear, stethoscope study.
Topics: Adult; Aged; Angina Pectoris; Atrial Function, Right; Cardiac Pacing, Artificial; Diastole; Double-B | 1994 |
[Comparison of the cardiodepressive effects of nifedipine, isradipine, nisoldipine and felodipine in patients with coronary heart disease].
Topics: Adult; Aged; Calcium Channel Blockers; Coronary Disease; Electrocardiography; Exercise Test; Felodip | 1993 |
Comparison of negative inotropic and vasodilator effects of isradipine and nifedipine after complete autonomic blockade in ischemic heart disease.
Topics: Autonomic Nerve Block; Depression, Chemical; Double-Blind Method; Heart Rate; Hemodynamics; Humans; | 1992 |
8 other studies available for isradipine and Heart Disease, Ischemic
| Article | Year |
|---|---|
[Effects of therapy with various groups of antianginal agents on life quality of the elderly with coronary heart disease and comorbid depression].
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Atenolol; Calcium Channel Blockers; Depression; Dise | 2005 |
Voltage-sensitive calcium channels and ischemia.
Topics: Animals; Calcium Channels; Dogs; Isradipine; Myocardial Ischemia; Swine | 1995 |
Effect of halothane on sarcolemmal calcium channels during myocardial ischemia and reperfusion.
Topics: Animals; Calcium Channels; Dogs; Halothane; Isradipine; Myocardial Ischemia; Myocardial Reperfusion; | 1994 |
Density of L-type calcium channels in ischaemically preconditioned porcine heart regions.
Topics: Animals; Calcium Channels; Female; Heart; Hemodynamics; Isradipine; Male; Myocardial Ischemia; Myoca | 1994 |
Halothane modifies ischemia-associated injury to the voltage-sensitive calcium channels in canine heart sarcolemma.
Topics: Animals; Binding Sites; Calcium Channels; Dogs; Electrophysiology; Halothane; Isradipine; Kinetics; | 1994 |
Are dihydropyridine receptors downregulated in the ischemic myocardium?
Topics: Animals; Calcium Channels; Calcium Channels, L-Type; Cell Membrane; Down-Regulation; Isradipine; Mic | 1995 |
Equal changes in L-type calcium channel density after 60 min of ischaemia in normal and ischaemically preconditioned porcine myocardium.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Female; Hemodynamics; In Vitro Techniques; Isch | 1996 |
Global ischemia increases the density of voltage-dependent calcium channels in porcine cardiac sarcolemma.
Topics: 5'-Nucleotidase; Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Heart Ventri | 1997 |