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isradipine and Elevated Cholesterol

isradipine has been researched along with Elevated Cholesterol in 8 studies

Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.

Research Excerpts

ExcerptRelevanceReference
" With the monotherapy of essential hypertension concurrent with hypercholesterolemia with the alpha 1-adrenoblocker Doxazosin, in addition to the agent's high antihypertensive effects, the authors noted its favourable action on lipid spectral parameters and platelet functional activity."3.69[Hypertension, diabetes mellitus, atherosclerosis: clinical manifestations of metabolic syndrome X. Prospects of pharmacological treatment]. ( Ivleva, AIa; Kobalava, ZhD; Moiseev, VS, 1995)
"108 male rabbits, aged 6 months, with experimental hypercholesterolemia and experimental abdominal aortic lesioning received different regimen of antiatherosclerotic treatment; 36 of them were treated with isradipine, a dihydropyridine calcium antagonist (0."3.68Concomitant aspirin treatment abolishes the antiatherosclerotic effects of the calcium channel blocker isradipine mediated by PGI2. ( Angelberger, P; Gerakakis, A; Keiler, A; Lupattelli, G; Pirich, C; Sinzinger, H; Virgolini, I, 1992)
"In isradipine-treated groups I/M ratios were significantly decreased (0."1.30Direct antiatherogenic activity of isradipine and lacidipine on neointimal lesions induced by perivascular manipulation in rabbits. ( Donetti, E; Fumagalli, R; Paoletti, R; Soma, MR, 1997)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (87.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moiseev, VS1
Ivleva, AIa1
Kobalava, ZhD1
Iurina, NA1
Sorokovoĭ, VI1
Romashova, MF1
Mochenova, NN1
Schmid, P1
Pirich, C2
Fitscha, P3
Pesau, B1
Virgolini, I3
Sinzinger, H4
Lupattelli, G3
Kritz, H1
O'Grady, J1
Donetti, E1
Fumagalli, R1
Paoletti, R1
Soma, MR1
Bracht, C1
Yan, XW1
Brunner-LaRocca, HP1
Sütsch, G1
Amann, FW1
Kiowski, W1
Keiler, A1
Gerakakis, A2
Angelberger, P2
Molinari, E1

Trials

2 trials available for isradipine and Elevated Cholesterol

ArticleYear
Isradipine increases platelet--low-density lipoprotein binding: evidence from ex-vivo studies in humans.
    Blood pressure. Supplement, 1994, Volume: 1

    Topics: Adult; Aged; Blood Platelets; Female; Hemodynamics; Humans; Hypercholesterolemia; Hypertension; Isra

1994
Isradipine improves endothelium-dependent vasodilation in normotensive coronary artery disease patients with hypercholesterolemia.
    Journal of hypertension, 2001, Volume: 19, Issue:5

    Topics: Aged; Blood Pressure; Cholesterol; Coronary Disease; Double-Blind Method; Endothelium, Vascular; For

2001

Other Studies

6 other studies available for isradipine and Elevated Cholesterol

ArticleYear
[Hypertension, diabetes mellitus, atherosclerosis: clinical manifestations of metabolic syndrome X. Prospects of pharmacological treatment].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 1995, Issue:5

    Topics: Anticholesteremic Agents; Arteriosclerosis; Diabetes Mellitus; Diabetes Mellitus, Type 2; Doxazosin;

1995
[The effect of eicosapentaenoic acid and the calcium antagonist isradipin on lipid metabolism and erythrocytes in experimental hypercholesterolemia in rabbits].
    Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 115, Issue:2

    Topics: Animals; Cholesterol; Eicosapentaenoic Acid; Erythrocytes; Fatty Acids, Nonesterified; Hypercholeste

1993
Prostaglandin I2-mediated upregulation of 125I-LDL-receptor binding by isradipine in normo- and hypercholesterolemic rabbits in vivo.
    Prostaglandins, 1996, Volume: 52, Issue:2

    Topics: Animals; Calcium Channel Blockers; Cohort Studies; Epoprostenol; Humans; Hypercholesterolemia; Iodin

1996
Direct antiatherogenic activity of isradipine and lacidipine on neointimal lesions induced by perivascular manipulation in rabbits.
    Pharmacological research, 1997, Volume: 35, Issue:5

    Topics: Animals; Arteriosclerosis; Calcium Channel Blockers; Carotid Arteries; Dihydropyridines; Dose-Respon

1997
Concomitant aspirin treatment abolishes the antiatherosclerotic effects of the calcium channel blocker isradipine mediated by PGI2.
    Agents and actions. Supplements, 1992, Volume: 37

    Topics: Animals; Aorta, Abdominal; Arteriosclerosis; Aspirin; Calcium Channel Blockers; Cholesterol; Dihydro

1992
Isradipine, a calcium-entry blocker, decreases vascular [125-I]low-density lipoprotein entry in hypercholesterolemic rabbits.
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:4

    Topics: Animals; Aorta, Thoracic; Blood Vessels; Calcium Channel Blockers; Epoprostenol; Hypercholesterolemi

1991