isradipine has been researched along with Diabetic Nephropathies in 4 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "On isradipine treatment these parameters remained unchanged." | 6.67 | A comparison of spirapril and isradipine in patients with diabetic nephropathy and hypertension. ( Christensen, P; Feldt-Rasmussen, B; Jensen, T; Nørgaard, K, 1993) |
| " In the long-term study presented here, the effects of isradipine, a dihydropyridine calcium antagonist, on the course of the nephropathy were investigated and compared with the effects of captopril in 31 African Americans with NIDDM and proteinuria (> or = 500 mg/day)." | 5.08 | Contrasting effects of calcium channel blockade versus converting enzyme inhibition on proteinuria in African Americans with non-insulin-dependent diabetes mellitus and nephropathy. ( Campbell, O; Guasch, A; Macon, E; Nzerue, C; Parham, M; Zayas, CF, 1997) |
| "On isradipine treatment these parameters remained unchanged." | 2.67 | A comparison of spirapril and isradipine in patients with diabetic nephropathy and hypertension. ( Christensen, P; Feldt-Rasmussen, B; Jensen, T; Nørgaard, K, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Christensen, PK | 1 |
| Akram, K | 1 |
| Kønig, KB | 1 |
| Parving, HH | 1 |
| Nørgaard, K | 1 |
| Jensen, T | 1 |
| Christensen, P | 1 |
| Feldt-Rasmussen, B | 1 |
| Guasch, A | 1 |
| Parham, M | 1 |
| Zayas, CF | 1 |
| Campbell, O | 1 |
| Nzerue, C | 1 |
| Macon, E | 1 |
| Nzerue, CM | 1 |
3 trials available for isradipine and Diabetic Nephropathies
| Article | Year |
|---|---|
Autoregulation of glomerular filtration rate in patients with type 2 diabetes during isradipine therapy.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clonidine; Cross-Over Studi | 2003 |
A comparison of spirapril and isradipine in patients with diabetic nephropathy and hypertension.
Topics: Adult; Albuminuria; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood P | 1993 |
Contrasting effects of calcium channel blockade versus converting enzyme inhibition on proteinuria in African Americans with non-insulin-dependent diabetes mellitus and nephropathy.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Black People; Calcium Channel Blockers; Capto | 1997 |
1 other study available for isradipine and Diabetic Nephropathies
| Article | Year |
|---|---|
Calcium antagonists and renal disease.
Topics: Calcium Channel Blockers; Diabetic Nephropathies; Humans; Isradipine | 1999 |