isradipine has been researched along with Diabetes Mellitus, Adult-Onset in 12 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In a prospective randomized study, 14 patients with NIDDM, hypertension, proteinuria, and renal insufficiency were given either isradipine (n = 7) or nifedipine XL (n = 7) for 6 months." | 5.08 | Effects of dihydropyridine calcium antagonists on albuminuria in patients with diabetes. ( Abbott, K; Bakris, GL; Smith, A, 1996) |
| " In the long-term study presented here, the effects of isradipine, a dihydropyridine calcium antagonist, on the course of the nephropathy were investigated and compared with the effects of captopril in 31 African Americans with NIDDM and proteinuria (> or = 500 mg/day)." | 5.08 | Contrasting effects of calcium channel blockade versus converting enzyme inhibition on proteinuria in African Americans with non-insulin-dependent diabetes mellitus and nephropathy. ( Campbell, O; Guasch, A; Macon, E; Nzerue, C; Parham, M; Zayas, CF, 1997) |
| " Therefore, the effects of isradipine, a new calcium antagonist, on glucose tolerance and insulin secretion during a 75-g oral glucose tolerance test (OGTT) and on ADP- and collagen-induced maximum first-wave platelet aggregation (Tmax%) were studied in 11 type II diabetic patients with borderline hypertension." | 5.06 | Platelet aggregation and metabolic control are not affected by calcium antagonist treatment in type II diabetes mellitus. ( Gisinger, C; Klauser, R; Prager, R; Schernthaner, G; Speiser, P, 1990) |
| " With the monotherapy of essential hypertension concurrent with hypercholesterolemia with the alpha 1-adrenoblocker Doxazosin, in addition to the agent's high antihypertensive effects, the authors noted its favourable action on lipid spectral parameters and platelet functional activity." | 3.69 | [Hypertension, diabetes mellitus, atherosclerosis: clinical manifestations of metabolic syndrome X. Prospects of pharmacological treatment]. ( Ivleva, AIa; Kobalava, ZhD; Moiseev, VS, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (91.67) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Christensen, PK | 1 |
| Akram, K | 1 |
| Kønig, KB | 1 |
| Parving, HH | 1 |
| Moiseev, VS | 1 |
| Ivleva, AIa | 1 |
| Kobalava, ZhD | 1 |
| Farsang, C | 1 |
| Kapocsi, J | 1 |
| Kiss, I | 1 |
| Török, E | 1 |
| Kerkovits, G | 1 |
| Holló, J | 1 |
| Jávor, T | 1 |
| Gomis, R | 1 |
| Vidal, J | 1 |
| Novials, A | 1 |
| Coves, MJ | 1 |
| Parreira, JM | 1 |
| Correia, LG | 1 |
| Pereira, E | 1 |
| Duarte, RS | 1 |
| Pape, E | 1 |
| Ferrara, LA | 1 |
| De Simone, G | 1 |
| Iannuzzi, R | 1 |
| Gaeta, I | 1 |
| D'Orta, G | 1 |
| Turco, S | 1 |
| Guida, L | 1 |
| Marotta, T | 1 |
| Abbott, K | 1 |
| Smith, A | 1 |
| Bakris, GL | 1 |
| Ranieri, G | 1 |
| Filitti, V | 1 |
| Andriani, A | 1 |
| Bonfantino, MV | 1 |
| Lamontanara, G | 1 |
| Cavallo, A | 1 |
| Milani, M | 1 |
| De Cesaris, R | 1 |
| Touyz, RM | 1 |
| Schiffrin, EL | 1 |
| Guasch, A | 1 |
| Parham, M | 1 |
| Zayas, CF | 1 |
| Campbell, O | 1 |
| Nzerue, C | 1 |
| Macon, E | 1 |
| Klauser, R | 2 |
| Speiser, P | 1 |
| Gisinger, C | 2 |
| Schernthaner, G | 2 |
| Prager, R | 2 |
| Gaube, S | 1 |
| Schnack, C | 1 |
| Küenburg, E | 1 |
11 trials available for isradipine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Autoregulation of glomerular filtration rate in patients with type 2 diabetes during isradipine therapy.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clonidine; Cross-Over Studi | 2003 |
Hungarian Isradipine Study (HIS): long-term (3-year) effects on blood pressure and plasma lipids.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Diabetes Mellitus, Type 2; Dru | 1994 |
Effects of isradipine and nifedipine retard in hypertensive patients with type II diabetes mellitus.
Topics: Blood Glucose; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Double-Blind Method; Female; | 1993 |
Antihypertensive efficacy, safety, and tolerability of isradipine in hypertensive patients with diabetes.
Topics: Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hy | 1993 |
Metabolic effects of isradipine in non-insulin-dependent diabetes mellitus (NIDDM) hypertensive patients.
Topics: Adult; Antihypertensive Agents; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Delayed-Act | 1995 |
Effects of dihydropyridine calcium antagonists on albuminuria in patients with diabetes.
Topics: Adult; Albuminuria; Calcium Channel Blockers; Cross-Over Studies; Diabetes Mellitus, Type 2; Diet, S | 1996 |
Effects of isradipine sustained release on platelet function and fibrinolysis in essential hypertensives with or without other risk factors.
Topics: Antihypertensive Agents; beta-Thromboglobulin; Blood Pressure; Calcium Channel Blockers; Delayed-Act | 1996 |
Treatment of non-insulin-dependent diabetic hypertensive patients with Ca2+ channel blockers is associated with increased platelet sensitivity to insulin.
Topics: Angiotensin II; Antihypertensive Agents; Blood Platelets; Blood Pressure; Calcium; Calcium Channel B | 1995 |
Contrasting effects of calcium channel blockade versus converting enzyme inhibition on proteinuria in African Americans with non-insulin-dependent diabetes mellitus and nephropathy.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Black People; Calcium Channel Blockers; Capto | 1997 |
Platelet aggregation and metabolic control are not affected by calcium antagonist treatment in type II diabetes mellitus.
Topics: Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diet; Double-Bli | 1990 |
Metabolic effects of isradipine versus hydrochlorothiazide in diabetes mellitus.
Topics: Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucos | 1991 |
1 other study available for isradipine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
[Hypertension, diabetes mellitus, atherosclerosis: clinical manifestations of metabolic syndrome X. Prospects of pharmacological treatment].
Topics: Anticholesteremic Agents; Arteriosclerosis; Diabetes Mellitus; Diabetes Mellitus, Type 2; Doxazosin; | 1995 |