isradipine has been researched along with Chronic Disease in 11 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The acute hemodynamic effects of isradipine on cardiac performance, at rest and during exercise, were examined in nine male patients aged 37 to 69 years with congestive heart failure due to ischemic heart disease." | 9.06 | Hemodynamic study of short- and long-term isradipine treatment in patients with chronic ischemic congestive heart failure. ( McGrath, BP; Newman, R; Older, P, 1989) |
| "Five hundred ninety outpatients aged 18 years or older with stable angina pectoris entered a multicenter, single-blind, nonrandomized, baseline-controlled study to assess the efficacy, safety, and tolerability of isradipine in doses of 2." | 9.06 | Safety and efficacy of isradipine, alone and in combination, in the treatment of angina pectoris. ( Nelson, DJ; Rüegg, PC, 1989) |
| "Nine cocaine abusers with cerebral blood flow (CBF) deficits (hypo-perfused areas) on HMPAO SPECT scans were compared to six without these deficits after six doses of isradipine (5 mg TID)." | 7.71 | Isradipine enhancement of cerebral blood flow in abstinent cocaine abusers with and without chronic perfusion deficits. ( Gottschalk, PC; Kosten, TR, 2002) |
| "The acute hemodynamic effects of isradipine on cardiac performance, at rest and during exercise, were examined in nine male patients aged 37 to 69 years with congestive heart failure due to ischemic heart disease." | 5.06 | Hemodynamic study of short- and long-term isradipine treatment in patients with chronic ischemic congestive heart failure. ( McGrath, BP; Newman, R; Older, P, 1989) |
| "Five hundred ninety outpatients aged 18 years or older with stable angina pectoris entered a multicenter, single-blind, nonrandomized, baseline-controlled study to assess the efficacy, safety, and tolerability of isradipine in doses of 2." | 5.06 | Safety and efficacy of isradipine, alone and in combination, in the treatment of angina pectoris. ( Nelson, DJ; Rüegg, PC, 1989) |
| "Nine cocaine abusers with cerebral blood flow (CBF) deficits (hypo-perfused areas) on HMPAO SPECT scans were compared to six without these deficits after six doses of isradipine (5 mg TID)." | 3.71 | Isradipine enhancement of cerebral blood flow in abstinent cocaine abusers with and without chronic perfusion deficits. ( Gottschalk, PC; Kosten, TR, 2002) |
| "isradipine was administered in increasing doses of 2." | 2.67 | [The treatment of chronic stable angina with isradipine. A cooperative Latin American study]. ( Alcocer, L; Arcos, R; Buzzi, A; Espinoza, J; Gómez, G; Kuster, F; Mayorga, E; Román, O; Romero, C; Tavella, N, 1991) |
| "Isradipine was simultaneously given orally (12C 5 mg) and i." | 1.28 | Pharmacokinetics of isradipine in patients with chronic liver disease. ( Cotting, J; Kutz, K; Laplanche, R; Nüesch, E; Reichen, J, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 8 (72.73) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gottschalk, PC | 1 |
| Kosten, TR | 1 |
| Chazova, IE | 2 |
| Belenkov, IuN | 2 |
| Mareev, VIu | 1 |
| Floria, VG | 1 |
| Sinitsyn, VE | 1 |
| Nakonechnikov, SN | 2 |
| Dmitriev, VV | 2 |
| Kurkova, KS | 1 |
| Arabidze, GG | 2 |
| Shklovskiĭ, VM | 1 |
| Rogova, AN | 1 |
| Metelitsa, TV | 2 |
| Vizel', TG | 1 |
| Rolachon, A | 1 |
| Bichard, P | 1 |
| Kezachian, G | 1 |
| Zarski, JP | 1 |
| van den Toren, EW | 1 |
| van Veldhuisen, DJ | 1 |
| van Bruggen, A | 1 |
| van den Broek, SA | 1 |
| van Gilst, WH | 1 |
| Lie, KI | 1 |
| Epifanova, ON | 1 |
| Rogoza, AN | 1 |
| Mychka, VB | 1 |
| Panchenko, EP | 1 |
| Dobrovol'skiĭ, AB | 1 |
| Titaeva, EV | 1 |
| Baklanova, NA | 1 |
| Román, O | 1 |
| Alcocer, L | 1 |
| Espinoza, J | 1 |
| Arcos, R | 1 |
| Gómez, G | 1 |
| Mayorga, E | 1 |
| Buzzi, A | 1 |
| Tavella, N | 1 |
| Romero, C | 1 |
| Kuster, F | 1 |
| Cotting, J | 1 |
| Reichen, J | 1 |
| Kutz, K | 1 |
| Laplanche, R | 1 |
| Nüesch, E | 1 |
| McGrath, BP | 1 |
| Newman, R | 1 |
| Older, P | 1 |
| Rüegg, PC | 1 |
| Nelson, DJ | 1 |
5 trials available for isradipine and Chronic Disease
| Article | Year |
|---|---|
[Lomir for the treatment of patients with essential hypertension and for the rehabilitation of patients with a history of cerebral circulatory disorder].
Topics: Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Chronic Disease; Circadian Rhythm; Fema | 1994 |
Acute hemodynamic and long-term clinical effects of isradipine in patients with coronary artery disease and chronic heart failure. A double-blind, placebo-controlled study.
Topics: Calcium Channel Blockers; Cardiac Output, Low; Chronic Disease; Coronary Disease; Double-Blind Metho | 1996 |
[The treatment of chronic stable angina with isradipine. A cooperative Latin American study].
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Dose-Res | 1991 |
Hemodynamic study of short- and long-term isradipine treatment in patients with chronic ischemic congestive heart failure.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Chronic Di | 1989 |
Safety and efficacy of isradipine, alone and in combination, in the treatment of angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Drug Combin | 1989 |
6 other studies available for isradipine and Chronic Disease
| Article | Year |
|---|---|
Isradipine enhancement of cerebral blood flow in abstinent cocaine abusers with and without chronic perfusion deficits.
Topics: Adult; Brain; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Cocaine-Relat | 2002 |
[The effect of Lomir (isradipine) on the tolerance for physical loading and on the gas exchange indices of patients with primary pulmonary hypertension].
Topics: Adult; Chronic Disease; Drug Evaluation; Exercise Test; Exercise Tolerance; Female; Hemodynamics; Hu | 1994 |
[Chronic diarrhea caused by isradipine].
Topics: Chronic Disease; Diarrhea; Female; Humans; Hypertension; Isradipine; Middle Aged | 1993 |
[The prolonged-action form of Lomir (isradipine) in the treatment of mild and moderate essential hypertension].
Topics: Adult; Antihypertensive Agents; Blood Pressure; Chronic Disease; Delayed-Action Preparations; Drug E | 1996 |
[The effect of long-term Fraxiparin treatment on hemostasis in patients with primary pulmonary hypertension].
Topics: Adult; Anticoagulants; Chronic Disease; Drug Evaluation; Drug Therapy, Combination; Female; Hemostas | 1997 |
Pharmacokinetics of isradipine in patients with chronic liver disease.
Topics: Administration, Oral; Adult; Aminopyrine; Bile Acids and Salts; Biotransformation; Chronic Disease; | 1990 |