Page last updated: 2024-10-29

isradipine and Chemical Dependence

isradipine has been researched along with Chemical Dependence in 8 studies

Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.

Research Excerpts

ExcerptRelevanceReference
"Pre-treatment with isradipine significantly reduced some of these positive subjective effects and craving for d-methamphetamine."2.69Isradipine, a dihydropyridine-class calcium channel antagonist, attenuates some of d-methamphetamine's positive subjective effects: a preliminary study. ( Ait-Daoud, N; Bordnick, PS; Johnson, BA; Roache, JD, 1999)
"Memories associated with substance use disorders, or substance-associated cues increase the likelihood of craving and relapse during abstinence."2.61Try to Remember: Interplay between Memory and Substance Use Disorder. ( Adam, RL; Das, S; Kumar, J; Mohamed, IN; Mohamed, RMP; Sidi, H; Yap, E, 2019)
"Isradipine inhibited lorazepam withdrawal symptoms, the effect being accompanied in the 24-h withdrawal group by significant decreases in the noradrenaline and dopamine content of the thalamus and hypothalamus and in the noradrenaline content of the mid-brain."1.30Influence of certain calcium-channel blockers on some aspects of lorazepam-dependence in mice. ( Attia, AS; Khayyal, MT; Saad, ES; Saad, SF, 1997)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (62.50)18.2507
2000's0 (0.00)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Natal, S1
Young, CC1
Kaur, K1
Gebhardt, ES1
Perrone, A1
Morikawa, H1
Tirado, C1
Smits, JAJ1
Mohamed, RMP1
Kumar, J1
Yap, E1
Mohamed, IN1
Sidi, H1
Adam, RL1
Das, S1
Harrington, M1
Reid, LD2
Pabello, NG1
Cramer, CM2
Hubbell, CL2
Saad, SF1
Khayyal, MT1
Attia, AS1
Saad, ES1
Johnson, B1
Barron, B1
Fang, B1
Lamki, L1
Wagner, L1
Wells, L1
Kenny, P1
Overton, D1
Dhother, S1
Abramson, D1
Chen, R1
Kramer, L1
Johnson, BA1
Roache, JD1
Bordnick, PS1
Ait-Daoud, N1

Reviews

2 reviews available for isradipine and Chemical Dependence

ArticleYear
Applications of isradipine in human addiction studies: A systematic literature review.
    Experimental and clinical psychopharmacology, 2023, Volume: 31, Issue:2

    Topics: Adult; Calcium Channel Blockers; Cocaine; Humans; Isradipine; Methamphetamine; Substance-Related Dis

2023
Try to Remember: Interplay between Memory and Substance Use Disorder.
    Current drug targets, 2019, Volume: 20, Issue:2

    Topics: Cues; Heterocyclic Compounds, 4 or More Rings; Humans; Isradipine; Memory, Long-Term; Molecular Targ

2019

Trials

1 trial available for isradipine and Chemical Dependence

ArticleYear
Isradipine, a dihydropyridine-class calcium channel antagonist, attenuates some of d-methamphetamine's positive subjective effects: a preliminary study.
    Psychopharmacology, 1999, Volume: 144, Issue:3

    Topics: Adrenergic Agents; Adult; Affect; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Do

1999

Other Studies

5 other studies available for isradipine and Chemical Dependence

ArticleYear
'Unlearning' addiction.
    Lab animal, 2015, Volume: 44, Issue:9

    Topics: Animals; Antiparkinson Agents; Isradipine; Learning; Male; Memory; Rats; Rats, Sprague-Dawley; Subst

2015
Isradipine in combination with naltrexone as a medicine for treating cocaine abuse.
    Life sciences, 1997, Volume: 60, Issue:8

    Topics: Animals; Calcium Channel Blockers; Cocaine; Drug Therapy, Combination; Electric Stimulation; Isradip

1997
Influence of certain calcium-channel blockers on some aspects of lorazepam-dependence in mice.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:3

    Topics: Animals; Brain Chemistry; Calcium Channel Blockers; Diltiazem; Dopamine; Flunarizine; Isradipine; Lo

1997
Isradipine prevents global and regional cocaine-induced changes in brain blood flow: a preliminary study.
    Psychopharmacology, 1998, Volume: 136, Issue:4

    Topics: Adult; Brain; Calcium Channel Blockers; Cerebral Arteries; Cocaine; Female; Humans; Isradipine; Male

1998
A combination of isradipine and naltrexone blocks cocaine's enhancement of a cocaine place preference.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:4

    Topics: Animals; Calcium Channel Blockers; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug;

1998