isradipine has been researched along with Cerebrovascular Disorders in 6 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nine cocaine abusers with cerebral blood flow (CBF) deficits (hypo-perfused areas) on HMPAO SPECT scans were compared to six without these deficits after six doses of isradipine (5 mg TID)." | 7.71 | Isradipine enhancement of cerebral blood flow in abstinent cocaine abusers with and without chronic perfusion deficits. ( Gottschalk, PC; Kosten, TR, 2002) |
| "9 years), at the dosage of 5 mg once a day." | 3.78 | [Metabolic tolerance of isradipine. Evaluation after three months of therapy]. ( Bernardini, A; Capone, A; Panuccio, D; Trabatti, MR, 1995) |
| "Nine cocaine abusers with cerebral blood flow (CBF) deficits (hypo-perfused areas) on HMPAO SPECT scans were compared to six without these deficits after six doses of isradipine (5 mg TID)." | 3.71 | Isradipine enhancement of cerebral blood flow in abstinent cocaine abusers with and without chronic perfusion deficits. ( Gottschalk, PC; Kosten, TR, 2002) |
| "Isradipine has proved to be the most potent and effective calcium antagonist for reducing the infarct size compared with other representatives of this class of drugs such as nimodipine, nicardipine and flunarizine." | 2.38 | Experimental studies with isradipine in stroke. ( Rudin, M; Sauter, A, 1990) |
| " Dose-response curves reveal that isradipine is one of the most potent and efficacious representatives of this class of compounds, reducing the infarct size by more than 60%." | 1.28 | Prevention of stroke and brain damage with calcium antagonists in animals. ( Rudin, M; Sauter, A, 1991) |
| " Using this model, dose-response curves for infarct size, measured by magnetic resonance imaging, and biochemical markers of infarction were obtained for various calcium antagonists." | 1.28 | Cerebrovascular, biochemical, and cytoprotective effects of isradipine in laboratory animals. ( Hof, RP; Rudin, M; Sauter, A; Wiederhold, KH, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gottschalk, PC | 1 |
| Kosten, TR | 1 |
| Panuccio, D | 1 |
| Trabatti, MR | 1 |
| Bernardini, A | 1 |
| Capone, A | 1 |
| Sauter, A | 4 |
| Rudin, M | 4 |
| Wiederhold, KH | 1 |
| Hof, RP | 1 |
2 reviews available for isradipine and Cerebrovascular Disorders
| Article | Year |
|---|---|
[Metabolic tolerance of isradipine. Evaluation after three months of therapy].
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorders; Coronary Artery Disease; | 1995 |
Experimental studies with isradipine in stroke.
Topics: Animals; Antihypertensive Agents; Cerebrovascular Circulation; Cerebrovascular Disorders; Disease Mo | 1990 |
1 trial available for isradipine and Cerebrovascular Disorders
| Article | Year |
|---|---|
[Metabolic tolerance of isradipine. Evaluation after three months of therapy].
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorders; Coronary Artery Disease; | 1995 |
4 other studies available for isradipine and Cerebrovascular Disorders
| Article | Year |
|---|---|
Isradipine enhancement of cerebral blood flow in abstinent cocaine abusers with and without chronic perfusion deficits.
Topics: Adult; Brain; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Cocaine-Relat | 2002 |
Calcium antagonists for reduction of brain damage in stroke.
Topics: Animals; Blood Pressure; Brain; Brain Damage, Chronic; Calcium Channel Blockers; Cerebrovascular Dis | 1990 |
Prevention of stroke and brain damage with calcium antagonists in animals.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain Damage, Chronic; Calcium Channel Blockers; C | 1991 |
Cerebrovascular, biochemical, and cytoprotective effects of isradipine in laboratory animals.
Topics: Animals; Antihypertensive Agents; Brain; Brain Chemistry; Brain Ischemia; Calcium Channel Blockers; | 1989 |