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isradipine and Cardiomegaly

isradipine has been researched along with Cardiomegaly in 8 studies

Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.

Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Research Excerpts

ExcerptRelevanceReference
"This was a study of the effectiveness of isradipine, a calcium antagonist of the dihydropyridine group, in reversing left ventricular hypertrophy (LVH) in patients with mild-to-moderate hypertension."9.07Regression of left ventricular hypertrophy in the short-term treatment of hypertension with isradipine. ( Abreu, P; Ajzen, H; Plavnik, F; Portela, JE; Ramos, OL; Saragoça, MA; Vanneta, A, 1991)
"In view of the possibility that cardiac hypertrophy may be reversed by isradipine, we studied the effect of two different doses of isradipine (1."7.67Pump performance after regression of cardiac hypertrophy following treatment of hypertension with isradipine. ( Amorim, MP; Cezaretti, ML; de Almeida, JB; Portela, J; Ramos, OL; Saragoça, MA, 1989)
"This was a study of the effectiveness of isradipine, a calcium antagonist of the dihydropyridine group, in reversing left ventricular hypertrophy (LVH) in patients with mild-to-moderate hypertension."5.07Regression of left ventricular hypertrophy in the short-term treatment of hypertension with isradipine. ( Abreu, P; Ajzen, H; Plavnik, F; Portela, JE; Ramos, OL; Saragoça, MA; Vanneta, A, 1991)
"In view of the possibility that cardiac hypertrophy may be reversed by isradipine, we studied the effect of two different doses of isradipine (1."3.67Pump performance after regression of cardiac hypertrophy following treatment of hypertension with isradipine. ( Amorim, MP; Cezaretti, ML; de Almeida, JB; Portela, J; Ramos, OL; Saragoça, MA, 1989)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's4 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Török, E1
Borbás, S1
Lengyel, M1
Zorándi, A1
Saragoça, MA3
Portela, JE2
Abreu, P2
Plavnik, F2
Ventura, R1
Vanneta, A2
Ajzen, H2
Ramos, OL3
Moore, RL1
Yelamarty, RV1
Misawa, H1
Scaduto, RC1
Pawlush, DG1
Elensky, M1
Cheung, JY1
Mayoux, E1
Callens, F1
Swynghedauw, B1
Charlemagne, D1
Dillon, JS1
Gu, XH1
Nayler, WG1
Nielsen, H1
Christensen, HR1
Christensen, KL1
Baandrup, U1
Jespersen, LT1
de Almeida, JB1
Amorim, MP1
Portela, J1
Cezaretti, ML1

Trials

2 trials available for isradipine and Cardiomegaly

ArticleYear
Regression of cardiac hypertrophy in hypertensive patients by long-term treatment with isradipine.
    Journal of cardiovascular pharmacology, 1992, Volume: 19 Suppl 3

    Topics: Adolescent; Adult; Aged; Calcium Channel Blockers; Cardiomegaly; Dihydropyridines; Drug Therapy, Com

1992
Regression of left ventricular hypertrophy in the short-term treatment of hypertension with isradipine.
    American journal of hypertension, 1991, Volume: 4, Issue:2 Pt 2

    Topics: Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Electrocardiography; Humans; Hypertension; I

1991

Other Studies

6 other studies available for isradipine and Cardiomegaly

ArticleYear
Reversal of left ventricular hypertrophy following treatment of hypertension with isradipine.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 3

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Dihydropyrid

1991
Altered Ca2+ dynamics in single cardiac myocytes from renovascular hypertensive rats.
    The American journal of physiology, 1991, Volume: 260, Issue:2 Pt 1

    Topics: Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Cardiomegaly; Cells, Cultured; Fur

1991
Adaptational process of the cardiac Ca2+ channels to pressure overload: biochemical and physiological properties of the dihydropyridine receptors in normal and hypertrophied rat hearts.
    Journal of cardiovascular pharmacology, 1988, Volume: 12, Issue:4

    Topics: Adaptation, Physiological; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels

1988
Effect of age and of hypertrophy on cardiac Ca2+ antagonist binding sites.
    Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:2

    Topics: Aging; Animals; Blood Pressure; Body Weight; Calcium Channels; Cardiomegaly; Cell Membrane; Dihydrop

1989
Antitrophic properties of antihypertensive drugs may depend solely on their blood pressure-lowering capability. A comparative study of isradipine, hydralazine, and metoprolol.
    The American journal of medicine, 1989, Apr-17, Volume: 86, Issue:4A

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Coronary V

1989
Pump performance after regression of cardiac hypertrophy following treatment of hypertension with isradipine.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6

    Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Cardiomegaly; Drug Evaluation, Preclinic

1989