isradipine has been researched along with Cardiomegaly in 8 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This was a study of the effectiveness of isradipine, a calcium antagonist of the dihydropyridine group, in reversing left ventricular hypertrophy (LVH) in patients with mild-to-moderate hypertension." | 9.07 | Regression of left ventricular hypertrophy in the short-term treatment of hypertension with isradipine. ( Abreu, P; Ajzen, H; Plavnik, F; Portela, JE; Ramos, OL; Saragoça, MA; Vanneta, A, 1991) |
| "In view of the possibility that cardiac hypertrophy may be reversed by isradipine, we studied the effect of two different doses of isradipine (1." | 7.67 | Pump performance after regression of cardiac hypertrophy following treatment of hypertension with isradipine. ( Amorim, MP; Cezaretti, ML; de Almeida, JB; Portela, J; Ramos, OL; Saragoça, MA, 1989) |
| "This was a study of the effectiveness of isradipine, a calcium antagonist of the dihydropyridine group, in reversing left ventricular hypertrophy (LVH) in patients with mild-to-moderate hypertension." | 5.07 | Regression of left ventricular hypertrophy in the short-term treatment of hypertension with isradipine. ( Abreu, P; Ajzen, H; Plavnik, F; Portela, JE; Ramos, OL; Saragoça, MA; Vanneta, A, 1991) |
| "In view of the possibility that cardiac hypertrophy may be reversed by isradipine, we studied the effect of two different doses of isradipine (1." | 3.67 | Pump performance after regression of cardiac hypertrophy following treatment of hypertension with isradipine. ( Amorim, MP; Cezaretti, ML; de Almeida, JB; Portela, J; Ramos, OL; Saragoça, MA, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Török, E | 1 |
| Borbás, S | 1 |
| Lengyel, M | 1 |
| Zorándi, A | 1 |
| Saragoça, MA | 3 |
| Portela, JE | 2 |
| Abreu, P | 2 |
| Plavnik, F | 2 |
| Ventura, R | 1 |
| Vanneta, A | 2 |
| Ajzen, H | 2 |
| Ramos, OL | 3 |
| Moore, RL | 1 |
| Yelamarty, RV | 1 |
| Misawa, H | 1 |
| Scaduto, RC | 1 |
| Pawlush, DG | 1 |
| Elensky, M | 1 |
| Cheung, JY | 1 |
| Mayoux, E | 1 |
| Callens, F | 1 |
| Swynghedauw, B | 1 |
| Charlemagne, D | 1 |
| Dillon, JS | 1 |
| Gu, XH | 1 |
| Nayler, WG | 1 |
| Nielsen, H | 1 |
| Christensen, HR | 1 |
| Christensen, KL | 1 |
| Baandrup, U | 1 |
| Jespersen, LT | 1 |
| de Almeida, JB | 1 |
| Amorim, MP | 1 |
| Portela, J | 1 |
| Cezaretti, ML | 1 |
2 trials available for isradipine and Cardiomegaly
| Article | Year |
|---|---|
Regression of cardiac hypertrophy in hypertensive patients by long-term treatment with isradipine.
Topics: Adolescent; Adult; Aged; Calcium Channel Blockers; Cardiomegaly; Dihydropyridines; Drug Therapy, Com | 1992 |
Regression of left ventricular hypertrophy in the short-term treatment of hypertension with isradipine.
Topics: Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Electrocardiography; Humans; Hypertension; I | 1991 |
6 other studies available for isradipine and Cardiomegaly
| Article | Year |
|---|---|
Reversal of left ventricular hypertrophy following treatment of hypertension with isradipine.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Dihydropyrid | 1991 |
Altered Ca2+ dynamics in single cardiac myocytes from renovascular hypertensive rats.
Topics: Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Cardiomegaly; Cells, Cultured; Fur | 1991 |
Adaptational process of the cardiac Ca2+ channels to pressure overload: biochemical and physiological properties of the dihydropyridine receptors in normal and hypertrophied rat hearts.
Topics: Adaptation, Physiological; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels | 1988 |
Effect of age and of hypertrophy on cardiac Ca2+ antagonist binding sites.
Topics: Aging; Animals; Blood Pressure; Body Weight; Calcium Channels; Cardiomegaly; Cell Membrane; Dihydrop | 1989 |
Antitrophic properties of antihypertensive drugs may depend solely on their blood pressure-lowering capability. A comparative study of isradipine, hydralazine, and metoprolol.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Coronary V | 1989 |
Pump performance after regression of cardiac hypertrophy following treatment of hypertension with isradipine.
Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Cardiomegaly; Drug Evaluation, Preclinic | 1989 |