isradipine has been researched along with Cardiac Failure in 10 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The acute hemodynamic effects of isradipine on cardiac performance, at rest and during exercise, were examined in nine male patients aged 37 to 69 years with congestive heart failure due to ischemic heart disease." | 9.06 | Hemodynamic study of short- and long-term isradipine treatment in patients with chronic ischemic congestive heart failure. ( McGrath, BP; Newman, R; Older, P, 1989) |
| "Isradipine is a dihydropyridine calcium antagonist used for the treatment of hypertension." | 8.78 | Cardiac effects of isradipine in patients with hypertension. ( Lund-Johansen, P, 1993) |
| "The chemistry, pharmacology, pharmacokinetics, clinical uses, adverse effects, and dosage of felodipine and isradipine are reviewed." | 6.38 | Felodipine and isradipine: new calcium-channel-blocking agents for the treatment of hypertension. ( Symes, LR; Walton, T, 1993) |
| "Continuous nitroglycerin (NTG) administration causes pharmacologic tolerance in humans and animals, whereas intermittent dosing is capable of avoiding or reducing tolerance development." | 5.29 | Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels. ( Bauer, JA; Fung, HL; Gopalakrishnan, M; Kwon, YW; Triggle, DJ; Zheng, W, 1993) |
| "The acute hemodynamic effects of isradipine on cardiac performance, at rest and during exercise, were examined in nine male patients aged 37 to 69 years with congestive heart failure due to ischemic heart disease." | 5.06 | Hemodynamic study of short- and long-term isradipine treatment in patients with chronic ischemic congestive heart failure. ( McGrath, BP; Newman, R; Older, P, 1989) |
| "Isradipine is a dihydropyridine calcium antagonist used for the treatment of hypertension." | 4.78 | Cardiac effects of isradipine in patients with hypertension. ( Lund-Johansen, P, 1993) |
| "To examine the status of ATP-sensitive K+ (K+ATP) channels and 1,4-dihydropyridine-sensitive Ca2+ (Ca2+DHP) channels during experimental cardiac failure, we have measured the radioligand binding properties of [3H]glyburide and [3H]PN 200 110, respectively, in tissue homogenates from the rat cardiac left ventricle, right ventricle, and brain 4 wk after myocardial infarction induced by left coronary artery ligation." | 3.68 | Regulation of K+ and Ca2+ channels in experimental cardiac failure. ( Bauer, JA; Fung, HL; Gopalakrishnan, M; Kwon, YW; Rutledge, A; Triggle, DJ, 1991) |
| "The chemistry, pharmacology, pharmacokinetics, clinical uses, adverse effects, and dosage of felodipine and isradipine are reviewed." | 2.38 | Felodipine and isradipine: new calcium-channel-blocking agents for the treatment of hypertension. ( Symes, LR; Walton, T, 1993) |
| "Continuous nitroglycerin (NTG) administration causes pharmacologic tolerance in humans and animals, whereas intermittent dosing is capable of avoiding or reducing tolerance development." | 1.29 | Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels. ( Bauer, JA; Fung, HL; Gopalakrishnan, M; Kwon, YW; Triggle, DJ; Zheng, W, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balijepalli, RC | 1 |
| Lokuta, AJ | 1 |
| Maertz, NA | 1 |
| Buck, JM | 1 |
| Haworth, RA | 1 |
| Valdivia, HH | 1 |
| Kamp, TJ | 1 |
| Bauer, JA | 2 |
| Fung, HL | 2 |
| Zheng, W | 1 |
| Kwon, YW | 2 |
| Gopalakrishnan, M | 2 |
| Triggle, DJ | 2 |
| Lund-Johansen, P | 1 |
| Walton, T | 1 |
| Symes, LR | 1 |
| Keung, EC | 1 |
| Toll, L | 1 |
| Ellis, M | 1 |
| Jensen, RA | 1 |
| Rutledge, A | 1 |
| Schwinger, RH | 1 |
| Böhm, M | 1 |
| Erdmann, E | 1 |
| Broudy, DR | 1 |
| Greenberg, BH | 1 |
| Siemienczuk, D | 2 |
| McGrath, BP | 1 |
| Newman, R | 1 |
| Older, P | 1 |
| Greenberg, B | 1 |
| Broudy, D | 1 |
2 reviews available for isradipine and Cardiac Failure
| Article | Year |
|---|---|
Cardiac effects of isradipine in patients with hypertension.
Topics: Coronary Artery Bypass; Heart; Heart Failure; Hemodynamics; Humans; Hypertension; Hypertrophy, Left | 1993 |
Felodipine and isradipine: new calcium-channel-blocking agents for the treatment of hypertension.
Topics: Angina Pectoris; Animals; Drug Interactions; Felodipine; Heart Failure; Hemodynamics; Humans; Hypert | 1993 |
1 trial available for isradipine and Cardiac Failure
| Article | Year |
|---|---|
Hemodynamic study of short- and long-term isradipine treatment in patients with chronic ischemic congestive heart failure.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Chronic Di | 1989 |
7 other studies available for isradipine and Cardiac Failure
| Article | Year |
|---|---|
Depletion of T-tubules and specific subcellular changes in sarcolemmal proteins in tachycardia-induced heart failure.
Topics: Animals; Calcium Channels, L-Type; Calcium-Transporting ATPases; Calsequestrin; Cardiac Pacing, Arti | 2003 |
Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels.
Topics: Administration, Cutaneous; Animals; Aorta, Thoracic; Binding Sites; Drug Tolerance; Glyburide; Heart | 1993 |
L-type cardiac calcium channels in doxorubicin cardiomyopathy in rats morphological, biochemical, and functional correlations.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Doxorubicin; Electric Conductivity; Fe | 1991 |
Regulation of K+ and Ca2+ channels in experimental cardiac failure.
Topics: Animals; Body Weight; Brain; Calcium Channel Blockers; Calcium Channels; Coronary Vessels; Dihydropy | 1991 |
Different negative inotropic activity of Ca2(+)-antagonists in human myocardial tissue.
Topics: Calcium Channel Blockers; Depression, Chemical; Diltiazem; Heart Atria; Heart Failure; Heart Transpl | 1990 |
Beneficial effects of the calcium antagonist PN 200-110 in patients with congestive heart failure.
Topics: Adult; Aged; Calcium Channel Blockers; Female; Heart Failure; Hemodynamics; Humans; Isradipine; Male | 1987 |
Hemodynamic effects of PN 200-110 (isradipine) in congestive heart failure.
Topics: Adult; Aged; Calcium Channel Blockers; Female; Follow-Up Studies; Heart Failure; Hemodynamics; Human | 1987 |