isradipine has been researched along with Brain Edema in 2 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| " No change in functional deficit was seen with isradipine with either dosing paradigm at 24 h post-MCA occlusion." | 5.30 | Effects of isradipine, an L-type calcium channel blocker on permanent and transient focal cerebral ischemia in spontaneously hypertensive rats. ( Campbell, CA; Hadingham, SJ; Hamilton, TC; King, PD; Mackay, KB; Patel, S; Stretton, JL, 1997) |
| " No change in functional deficit was seen with isradipine with either dosing paradigm at 24 h post-MCA occlusion." | 1.30 | Effects of isradipine, an L-type calcium channel blocker on permanent and transient focal cerebral ischemia in spontaneously hypertensive rats. ( Campbell, CA; Hadingham, SJ; Hamilton, TC; King, PD; Mackay, KB; Patel, S; Stretton, JL, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Campbell, CA | 1 |
| Mackay, KB | 1 |
| Patel, S | 1 |
| King, PD | 1 |
| Stretton, JL | 1 |
| Hadingham, SJ | 1 |
| Hamilton, TC | 1 |
| Abe, K | 1 |
| Kogure, K | 1 |
| Watanabe, T | 1 |
2 other studies available for isradipine and Brain Edema
| Article | Year |
|---|---|
Effects of isradipine, an L-type calcium channel blocker on permanent and transient focal cerebral ischemia in spontaneously hypertensive rats.
Topics: Animals; Behavior, Animal; Brain Damage, Chronic; Brain Edema; Brain Ischemia; Calcium Channel Block | 1997 |
Prevention of ischemic and postischemic brain edema by a novel calcium antagonist (PN200-110).
Topics: Animals; Autoradiography; Brain Edema; Brain Ischemia; Calcium; Calcium Channel Blockers; Isradipine | 1988 |