isradipine has been researched along with Brain Damage, Chronic in 3 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Brain Damage, Chronic: A condition characterized by long-standing brain dysfunction or damage, usually of three months duration or longer. Potential etiologies include BRAIN INFARCTION; certain NEURODEGENERATIVE DISORDERS; CRANIOCEREBRAL TRAUMA; ANOXIA, BRAIN; ENCEPHALITIS; certain NEUROTOXICITY SYNDROMES; metabolic disorders (see BRAIN DISEASES, METABOLIC); and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " No change in functional deficit was seen with isradipine with either dosing paradigm at 24 h post-MCA occlusion." | 5.30 | Effects of isradipine, an L-type calcium channel blocker on permanent and transient focal cerebral ischemia in spontaneously hypertensive rats. ( Campbell, CA; Hadingham, SJ; Hamilton, TC; King, PD; Mackay, KB; Patel, S; Stretton, JL, 1997) |
| " No change in functional deficit was seen with isradipine with either dosing paradigm at 24 h post-MCA occlusion." | 1.30 | Effects of isradipine, an L-type calcium channel blocker on permanent and transient focal cerebral ischemia in spontaneously hypertensive rats. ( Campbell, CA; Hadingham, SJ; Hamilton, TC; King, PD; Mackay, KB; Patel, S; Stretton, JL, 1997) |
| " Dose-response curves reveal that isradipine is one of the most potent and efficacious representatives of this class of compounds, reducing the infarct size by more than 60%." | 1.28 | Prevention of stroke and brain damage with calcium antagonists in animals. ( Rudin, M; Sauter, A, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Campbell, CA | 1 |
| Mackay, KB | 1 |
| Patel, S | 1 |
| King, PD | 1 |
| Stretton, JL | 1 |
| Hadingham, SJ | 1 |
| Hamilton, TC | 1 |
| Sauter, A | 2 |
| Rudin, M | 2 |
3 other studies available for isradipine and Brain Damage, Chronic
| Article | Year |
|---|---|
Effects of isradipine, an L-type calcium channel blocker on permanent and transient focal cerebral ischemia in spontaneously hypertensive rats.
Topics: Animals; Behavior, Animal; Brain Damage, Chronic; Brain Edema; Brain Ischemia; Calcium Channel Block | 1997 |
Calcium antagonists for reduction of brain damage in stroke.
Topics: Animals; Blood Pressure; Brain; Brain Damage, Chronic; Calcium Channel Blockers; Cerebrovascular Dis | 1990 |
Prevention of stroke and brain damage with calcium antagonists in animals.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain Damage, Chronic; Calcium Channel Blockers; C | 1991 |