isradipine has been researched along with Bipolar Disorder in 3 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Motivated by genetic association data implicating L-type calcium channels in bipolar disorder liability, we sought to estimate the tolerability, safety, and efficacy of isradipine in the adjunctive treatment of bipolar depression." | 3.80 | Pilot investigation of isradipine in the treatment of bipolar depression motivated by genome-wide association. ( Blumenthal, SR; Hay, A; Iosifescu, DV; Ostacher, MJ; Perlis, RH; Sklar, P, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ostacher, MJ | 1 |
| Iosifescu, DV | 1 |
| Hay, A | 1 |
| Blumenthal, SR | 1 |
| Sklar, P | 1 |
| Perlis, RH | 1 |
| Cipriani, A | 1 |
| Saunders, K | 1 |
| Attenburrow, MJ | 1 |
| Stefaniak, J | 1 |
| Panchal, P | 1 |
| Stockton, S | 1 |
| Lane, TA | 1 |
| Tunbridge, EM | 1 |
| Geddes, JR | 1 |
| Harrison, PJ | 1 |
| Pazzaglia, PJ | 1 |
| Post, RM | 1 |
| Ketter, TA | 1 |
| Callahan, AM | 1 |
| Marangell, LB | 1 |
| Frye, MA | 1 |
| George, MS | 1 |
| Kimbrell, TA | 1 |
| Leverich, GS | 1 |
| Cora-Locatelli, G | 1 |
| Luckenbaugh, D | 1 |
1 review available for isradipine and Bipolar Disorder
| Article | Year |
|---|---|
A systematic review of calcium channel antagonists in bipolar disorder and some considerations for their future development.
Topics: Bipolar Disorder; Calcium Channel Blockers; Calcium Channels, L-Type; Double-Blind Method; Humans; I | 2016 |
1 trial available for isradipine and Bipolar Disorder
| Article | Year |
|---|---|
Nimodipine monotherapy and carbamazepine augmentation in patients with refractory recurrent affective illness.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Depressive Disor | 1998 |
1 other study available for isradipine and Bipolar Disorder
| Article | Year |
|---|---|
Pilot investigation of isradipine in the treatment of bipolar depression motivated by genome-wide association.
Topics: Adult; Bipolar Disorder; Calcium Channel Blockers; Calcium Channels, L-Type; Female; Genome-Wide Ass | 2014 |