isradipine has been researched along with Arrhythmias, Cardiac in 5 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to evaluate in 45 hypertensive patients with left ventricular hypertrophy (LVH) the effects of a 6-month course with one of three different antihypertensive regimens (the calcium channel blocker isradipine, the angiotensin converting enzyme inhibitor spirapril in monotherapy, or a combination of the two drugs, n = 15 per group) on blood pressure, LVH regression, and various functional correlates of LVH." | 9.08 | Comparison of spirapril, isradipine, or combination in hypertensive patients with left ventricular hypertrophy: effects on LVH regression and arrhythmogenic propensity. ( Beldekos, D; Bresnahan, M; Cokkinos, DV; Foussas, S; Gavras, H; Gavras, I; Handanis, S; Haralabidis, G; Hatzissavas, J; Manolis, AJ, 1998) |
| "This study was designed to evaluate in 45 hypertensive patients with left ventricular hypertrophy (LVH) the effects of a 6-month course with one of three different antihypertensive regimens (the calcium channel blocker isradipine, the angiotensin converting enzyme inhibitor spirapril in monotherapy, or a combination of the two drugs, n = 15 per group) on blood pressure, LVH regression, and various functional correlates of LVH." | 5.08 | Comparison of spirapril, isradipine, or combination in hypertensive patients with left ventricular hypertrophy: effects on LVH regression and arrhythmogenic propensity. ( Beldekos, D; Bresnahan, M; Cokkinos, DV; Foussas, S; Gavras, H; Gavras, I; Handanis, S; Haralabidis, G; Hatzissavas, J; Manolis, AJ, 1998) |
| "Isradipine dose was 30 mg sustained release nightly plus 15 mg immediate release 2 hr before cocaine infusion." | 2.71 | Effects of repeated-dose isradipine on the abuse liability of cocaine. ( Ait-Daoud, N; Johnson, BA; Mauldin, JB; Murff, WL; Roache, JD; Thornton, JE; Wells, LT, 2005) |
| "In isolated hearts from wild type mice, arrhythmia was induced by superfusion with a solution containing 200 nM SNX-482, a blocker of some R-type voltage gated Ca2+ channels, suggesting that R-type channels containing the splice variant Cav2." | 1.32 | Arrhythmia in isolated prenatal hearts after ablation of the Cav2.3 (alpha1E) subunit of voltage-gated Ca2+ channels. ( Henry, M; Hescheler, J; Krieger, A; Liu, HL; Lu, ZJ; Pereverzev, A; Schneider, T; Smyth, N; Weiergräber, M, 2004) |
| "The same type of arrhythmia was observed combining low concentrations of mibefradil with amlodipine, or with gallopamil, respectively." | 1.31 | Pharmacodynamic interaction between mibefradil and other calcium channel blockers. ( Antepohl, W; Haaf, O; Herzig, S; Huber, I; Matthes, J; Striessnig, J, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, ZJ | 1 |
| Pereverzev, A | 1 |
| Liu, HL | 1 |
| Weiergräber, M | 1 |
| Henry, M | 1 |
| Krieger, A | 1 |
| Smyth, N | 1 |
| Hescheler, J | 1 |
| Schneider, T | 1 |
| Roache, JD | 1 |
| Johnson, BA | 1 |
| Ait-Daoud, N | 1 |
| Mauldin, JB | 1 |
| Thornton, JE | 1 |
| Wells, LT | 1 |
| Murff, WL | 1 |
| Saragoça, MA | 1 |
| Cassiolatto, JL | 1 |
| Vanetta, AM | 1 |
| Canziani, ME | 1 |
| Abreu, P | 1 |
| Ventura, RT | 1 |
| Ramos, OL | 1 |
| Manolis, AJ | 1 |
| Beldekos, D | 1 |
| Handanis, S | 1 |
| Haralabidis, G | 1 |
| Hatzissavas, J | 1 |
| Foussas, S | 1 |
| Cokkinos, DV | 1 |
| Bresnahan, M | 1 |
| Gavras, I | 1 |
| Gavras, H | 1 |
| Matthes, J | 1 |
| Huber, I | 1 |
| Haaf, O | 1 |
| Antepohl, W | 1 |
| Striessnig, J | 1 |
| Herzig, S | 1 |
3 trials available for isradipine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Effects of repeated-dose isradipine on the abuse liability of cocaine.
Topics: Acetaminophen; Administration, Oral; Adult; Analysis of Variance; Arrhythmias, Cardiac; Calcium Chan | 2005 |
Reversal of left ventricular hypertrophy with isradipine induces diminution of cardiac arrhythmias.
Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left | 1993 |
Comparison of spirapril, isradipine, or combination in hypertensive patients with left ventricular hypertrophy: effects on LVH regression and arrhythmogenic propensity.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Press | 1998 |
2 other studies available for isradipine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Arrhythmia in isolated prenatal hearts after ablation of the Cav2.3 (alpha1E) subunit of voltage-gated Ca2+ channels.
Topics: Alternative Splicing; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels; Cal | 2004 |
Pharmacodynamic interaction between mibefradil and other calcium channel blockers.
Topics: Amlodipine; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels, L-Type; Cell | 2000 |