isradipine has been researched along with Arrhythmia in 5 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
Excerpt | Relevance | Reference |
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"This study was designed to evaluate in 45 hypertensive patients with left ventricular hypertrophy (LVH) the effects of a 6-month course with one of three different antihypertensive regimens (the calcium channel blocker isradipine, the angiotensin converting enzyme inhibitor spirapril in monotherapy, or a combination of the two drugs, n = 15 per group) on blood pressure, LVH regression, and various functional correlates of LVH." | 9.08 | Comparison of spirapril, isradipine, or combination in hypertensive patients with left ventricular hypertrophy: effects on LVH regression and arrhythmogenic propensity. ( Beldekos, D; Bresnahan, M; Cokkinos, DV; Foussas, S; Gavras, H; Gavras, I; Handanis, S; Haralabidis, G; Hatzissavas, J; Manolis, AJ, 1998) |
"This study was designed to evaluate in 45 hypertensive patients with left ventricular hypertrophy (LVH) the effects of a 6-month course with one of three different antihypertensive regimens (the calcium channel blocker isradipine, the angiotensin converting enzyme inhibitor spirapril in monotherapy, or a combination of the two drugs, n = 15 per group) on blood pressure, LVH regression, and various functional correlates of LVH." | 5.08 | Comparison of spirapril, isradipine, or combination in hypertensive patients with left ventricular hypertrophy: effects on LVH regression and arrhythmogenic propensity. ( Beldekos, D; Bresnahan, M; Cokkinos, DV; Foussas, S; Gavras, H; Gavras, I; Handanis, S; Haralabidis, G; Hatzissavas, J; Manolis, AJ, 1998) |
"Isradipine dose was 30 mg sustained release nightly plus 15 mg immediate release 2 hr before cocaine infusion." | 2.71 | Effects of repeated-dose isradipine on the abuse liability of cocaine. ( Ait-Daoud, N; Johnson, BA; Mauldin, JB; Murff, WL; Roache, JD; Thornton, JE; Wells, LT, 2005) |
"In isolated hearts from wild type mice, arrhythmia was induced by superfusion with a solution containing 200 nM SNX-482, a blocker of some R-type voltage gated Ca2+ channels, suggesting that R-type channels containing the splice variant Cav2." | 1.32 | Arrhythmia in isolated prenatal hearts after ablation of the Cav2.3 (alpha1E) subunit of voltage-gated Ca2+ channels. ( Henry, M; Hescheler, J; Krieger, A; Liu, HL; Lu, ZJ; Pereverzev, A; Schneider, T; Smyth, N; Weiergräber, M, 2004) |
"The same type of arrhythmia was observed combining low concentrations of mibefradil with amlodipine, or with gallopamil, respectively." | 1.31 | Pharmacodynamic interaction between mibefradil and other calcium channel blockers. ( Antepohl, W; Haaf, O; Herzig, S; Huber, I; Matthes, J; Striessnig, J, 2000) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (40.00) | 18.2507 |
2000's | 3 (60.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Lu, ZJ | 1 |
Pereverzev, A | 1 |
Liu, HL | 1 |
Weiergräber, M | 1 |
Henry, M | 1 |
Krieger, A | 1 |
Smyth, N | 1 |
Hescheler, J | 1 |
Schneider, T | 1 |
Roache, JD | 1 |
Johnson, BA | 1 |
Ait-Daoud, N | 1 |
Mauldin, JB | 1 |
Thornton, JE | 1 |
Wells, LT | 1 |
Murff, WL | 1 |
Saragoça, MA | 1 |
Cassiolatto, JL | 1 |
Vanetta, AM | 1 |
Canziani, ME | 1 |
Abreu, P | 1 |
Ventura, RT | 1 |
Ramos, OL | 1 |
Manolis, AJ | 1 |
Beldekos, D | 1 |
Handanis, S | 1 |
Haralabidis, G | 1 |
Hatzissavas, J | 1 |
Foussas, S | 1 |
Cokkinos, DV | 1 |
Bresnahan, M | 1 |
Gavras, I | 1 |
Gavras, H | 1 |
Matthes, J | 1 |
Huber, I | 1 |
Haaf, O | 1 |
Antepohl, W | 1 |
Striessnig, J | 1 |
Herzig, S | 1 |
3 trials available for isradipine and Arrhythmia
Article | Year |
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Effects of repeated-dose isradipine on the abuse liability of cocaine.
Topics: Acetaminophen; Administration, Oral; Adult; Analysis of Variance; Arrhythmias, Cardiac; Calcium Chan | 2005 |
Reversal of left ventricular hypertrophy with isradipine induces diminution of cardiac arrhythmias.
Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left | 1993 |
Comparison of spirapril, isradipine, or combination in hypertensive patients with left ventricular hypertrophy: effects on LVH regression and arrhythmogenic propensity.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Press | 1998 |
2 other studies available for isradipine and Arrhythmia
Article | Year |
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Arrhythmia in isolated prenatal hearts after ablation of the Cav2.3 (alpha1E) subunit of voltage-gated Ca2+ channels.
Topics: Alternative Splicing; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels; Cal | 2004 |
Pharmacodynamic interaction between mibefradil and other calcium channel blockers.
Topics: Amlodipine; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels, L-Type; Cell | 2000 |