Page last updated: 2024-10-29

isradipine and Arrhythmia

isradipine has been researched along with Arrhythmia in 5 studies

Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.

Research Excerpts

ExcerptRelevanceReference
"This study was designed to evaluate in 45 hypertensive patients with left ventricular hypertrophy (LVH) the effects of a 6-month course with one of three different antihypertensive regimens (the calcium channel blocker isradipine, the angiotensin converting enzyme inhibitor spirapril in monotherapy, or a combination of the two drugs, n = 15 per group) on blood pressure, LVH regression, and various functional correlates of LVH."9.08Comparison of spirapril, isradipine, or combination in hypertensive patients with left ventricular hypertrophy: effects on LVH regression and arrhythmogenic propensity. ( Beldekos, D; Bresnahan, M; Cokkinos, DV; Foussas, S; Gavras, H; Gavras, I; Handanis, S; Haralabidis, G; Hatzissavas, J; Manolis, AJ, 1998)
"This study was designed to evaluate in 45 hypertensive patients with left ventricular hypertrophy (LVH) the effects of a 6-month course with one of three different antihypertensive regimens (the calcium channel blocker isradipine, the angiotensin converting enzyme inhibitor spirapril in monotherapy, or a combination of the two drugs, n = 15 per group) on blood pressure, LVH regression, and various functional correlates of LVH."5.08Comparison of spirapril, isradipine, or combination in hypertensive patients with left ventricular hypertrophy: effects on LVH regression and arrhythmogenic propensity. ( Beldekos, D; Bresnahan, M; Cokkinos, DV; Foussas, S; Gavras, H; Gavras, I; Handanis, S; Haralabidis, G; Hatzissavas, J; Manolis, AJ, 1998)
"Isradipine dose was 30 mg sustained release nightly plus 15 mg immediate release 2 hr before cocaine infusion."2.71Effects of repeated-dose isradipine on the abuse liability of cocaine. ( Ait-Daoud, N; Johnson, BA; Mauldin, JB; Murff, WL; Roache, JD; Thornton, JE; Wells, LT, 2005)
"In isolated hearts from wild type mice, arrhythmia was induced by superfusion with a solution containing 200 nM SNX-482, a blocker of some R-type voltage gated Ca2+ channels, suggesting that R-type channels containing the splice variant Cav2."1.32Arrhythmia in isolated prenatal hearts after ablation of the Cav2.3 (alpha1E) subunit of voltage-gated Ca2+ channels. ( Henry, M; Hescheler, J; Krieger, A; Liu, HL; Lu, ZJ; Pereverzev, A; Schneider, T; Smyth, N; Weiergräber, M, 2004)
"The same type of arrhythmia was observed combining low concentrations of mibefradil with amlodipine, or with gallopamil, respectively."1.31Pharmacodynamic interaction between mibefradil and other calcium channel blockers. ( Antepohl, W; Haaf, O; Herzig, S; Huber, I; Matthes, J; Striessnig, J, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lu, ZJ1
Pereverzev, A1
Liu, HL1
Weiergräber, M1
Henry, M1
Krieger, A1
Smyth, N1
Hescheler, J1
Schneider, T1
Roache, JD1
Johnson, BA1
Ait-Daoud, N1
Mauldin, JB1
Thornton, JE1
Wells, LT1
Murff, WL1
Saragoça, MA1
Cassiolatto, JL1
Vanetta, AM1
Canziani, ME1
Abreu, P1
Ventura, RT1
Ramos, OL1
Manolis, AJ1
Beldekos, D1
Handanis, S1
Haralabidis, G1
Hatzissavas, J1
Foussas, S1
Cokkinos, DV1
Bresnahan, M1
Gavras, I1
Gavras, H1
Matthes, J1
Huber, I1
Haaf, O1
Antepohl, W1
Striessnig, J1
Herzig, S1

Trials

3 trials available for isradipine and Arrhythmia

ArticleYear
Effects of repeated-dose isradipine on the abuse liability of cocaine.
    Experimental and clinical psychopharmacology, 2005, Volume: 13, Issue:4

    Topics: Acetaminophen; Administration, Oral; Adult; Analysis of Variance; Arrhythmias, Cardiac; Calcium Chan

2005
Reversal of left ventricular hypertrophy with isradipine induces diminution of cardiac arrhythmias.
    American journal of hypertension, 1993, Volume: 6, Issue:3 Pt 2

    Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left

1993
Comparison of spirapril, isradipine, or combination in hypertensive patients with left ventricular hypertrophy: effects on LVH regression and arrhythmogenic propensity.
    American journal of hypertension, 1998, Volume: 11, Issue:6 Pt 1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Press

1998

Other Studies

2 other studies available for isradipine and Arrhythmia

ArticleYear
Arrhythmia in isolated prenatal hearts after ablation of the Cav2.3 (alpha1E) subunit of voltage-gated Ca2+ channels.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2004, Volume: 14, Issue:1-2

    Topics: Alternative Splicing; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels; Cal

2004
Pharmacodynamic interaction between mibefradil and other calcium channel blockers.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:6

    Topics: Amlodipine; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels, L-Type; Cell

2000