isradipine has been researched along with Arrhythmia in 5 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to evaluate in 45 hypertensive patients with left ventricular hypertrophy (LVH) the effects of a 6-month course with one of three different antihypertensive regimens (the calcium channel blocker isradipine, the angiotensin converting enzyme inhibitor spirapril in monotherapy, or a combination of the two drugs, n = 15 per group) on blood pressure, LVH regression, and various functional correlates of LVH." | 9.08 | Comparison of spirapril, isradipine, or combination in hypertensive patients with left ventricular hypertrophy: effects on LVH regression and arrhythmogenic propensity. ( Beldekos, D; Bresnahan, M; Cokkinos, DV; Foussas, S; Gavras, H; Gavras, I; Handanis, S; Haralabidis, G; Hatzissavas, J; Manolis, AJ, 1998) |
| "This study was designed to evaluate in 45 hypertensive patients with left ventricular hypertrophy (LVH) the effects of a 6-month course with one of three different antihypertensive regimens (the calcium channel blocker isradipine, the angiotensin converting enzyme inhibitor spirapril in monotherapy, or a combination of the two drugs, n = 15 per group) on blood pressure, LVH regression, and various functional correlates of LVH." | 5.08 | Comparison of spirapril, isradipine, or combination in hypertensive patients with left ventricular hypertrophy: effects on LVH regression and arrhythmogenic propensity. ( Beldekos, D; Bresnahan, M; Cokkinos, DV; Foussas, S; Gavras, H; Gavras, I; Handanis, S; Haralabidis, G; Hatzissavas, J; Manolis, AJ, 1998) |
| "Isradipine dose was 30 mg sustained release nightly plus 15 mg immediate release 2 hr before cocaine infusion." | 2.71 | Effects of repeated-dose isradipine on the abuse liability of cocaine. ( Ait-Daoud, N; Johnson, BA; Mauldin, JB; Murff, WL; Roache, JD; Thornton, JE; Wells, LT, 2005) |
| "In isolated hearts from wild type mice, arrhythmia was induced by superfusion with a solution containing 200 nM SNX-482, a blocker of some R-type voltage gated Ca2+ channels, suggesting that R-type channels containing the splice variant Cav2." | 1.32 | Arrhythmia in isolated prenatal hearts after ablation of the Cav2.3 (alpha1E) subunit of voltage-gated Ca2+ channels. ( Henry, M; Hescheler, J; Krieger, A; Liu, HL; Lu, ZJ; Pereverzev, A; Schneider, T; Smyth, N; Weiergräber, M, 2004) |
| "The same type of arrhythmia was observed combining low concentrations of mibefradil with amlodipine, or with gallopamil, respectively." | 1.31 | Pharmacodynamic interaction between mibefradil and other calcium channel blockers. ( Antepohl, W; Haaf, O; Herzig, S; Huber, I; Matthes, J; Striessnig, J, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, ZJ | 1 |
| Pereverzev, A | 1 |
| Liu, HL | 1 |
| Weiergräber, M | 1 |
| Henry, M | 1 |
| Krieger, A | 1 |
| Smyth, N | 1 |
| Hescheler, J | 1 |
| Schneider, T | 1 |
| Roache, JD | 1 |
| Johnson, BA | 1 |
| Ait-Daoud, N | 1 |
| Mauldin, JB | 1 |
| Thornton, JE | 1 |
| Wells, LT | 1 |
| Murff, WL | 1 |
| Saragoça, MA | 1 |
| Cassiolatto, JL | 1 |
| Vanetta, AM | 1 |
| Canziani, ME | 1 |
| Abreu, P | 1 |
| Ventura, RT | 1 |
| Ramos, OL | 1 |
| Manolis, AJ | 1 |
| Beldekos, D | 1 |
| Handanis, S | 1 |
| Haralabidis, G | 1 |
| Hatzissavas, J | 1 |
| Foussas, S | 1 |
| Cokkinos, DV | 1 |
| Bresnahan, M | 1 |
| Gavras, I | 1 |
| Gavras, H | 1 |
| Matthes, J | 1 |
| Huber, I | 1 |
| Haaf, O | 1 |
| Antepohl, W | 1 |
| Striessnig, J | 1 |
| Herzig, S | 1 |
3 trials available for isradipine and Arrhythmia
| Article | Year |
|---|---|
Effects of repeated-dose isradipine on the abuse liability of cocaine.
Topics: Acetaminophen; Administration, Oral; Adult; Analysis of Variance; Arrhythmias, Cardiac; Calcium Chan | 2005 |
Reversal of left ventricular hypertrophy with isradipine induces diminution of cardiac arrhythmias.
Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left | 1993 |
Comparison of spirapril, isradipine, or combination in hypertensive patients with left ventricular hypertrophy: effects on LVH regression and arrhythmogenic propensity.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Press | 1998 |
2 other studies available for isradipine and Arrhythmia
| Article | Year |
|---|---|
Arrhythmia in isolated prenatal hearts after ablation of the Cav2.3 (alpha1E) subunit of voltage-gated Ca2+ channels.
Topics: Alternative Splicing; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels; Cal | 2004 |
Pharmacodynamic interaction between mibefradil and other calcium channel blockers.
Topics: Amlodipine; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Channels, L-Type; Cell | 2000 |