isradipine has been researched along with Anterior Choroidal Artery Infarction in 7 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The L-type calcium channel blocker isradipine was devoid of neuroprotective activity in focal and global models of cerebral ischemia in three species of normotensive animals." | 7.69 | Failure of isradipine to reduce infarct size in mouse, gerbil, and rat models of cerebral ischemia. ( Bailey, SJ; Hamilton, TC; Harrison, DC; Hunter, AJ; King, PD; Roberts, JC; Rothaul, AL; Samson, NA; Wood, NI, 1995) |
| "The L-type calcium channel blocker isradipine was devoid of neuroprotective activity in focal and global models of cerebral ischemia in three species of normotensive animals." | 3.69 | Failure of isradipine to reduce infarct size in mouse, gerbil, and rat models of cerebral ischemia. ( Bailey, SJ; Hamilton, TC; Harrison, DC; Hunter, AJ; King, PD; Roberts, JC; Rothaul, AL; Samson, NA; Wood, NI, 1995) |
| " Using this model, dose-response curves for infarct size, measured by magnetic resonance imaging, and biochemical markers of infarction were obtained for various calcium antagonists." | 1.28 | Cerebrovascular, biochemical, and cytoprotective effects of isradipine in laboratory animals. ( Hof, RP; Rudin, M; Sauter, A; Wiederhold, KH, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bailey, SJ | 1 |
| Wood, NI | 1 |
| Samson, NA | 1 |
| Rothaul, AL | 1 |
| Roberts, JC | 1 |
| King, PD | 1 |
| Hamilton, TC | 1 |
| Harrison, DC | 1 |
| Hunter, AJ | 1 |
| Sauter, A | 5 |
| Rudin, M | 5 |
| Reese, T | 1 |
| Pórszász, R | 1 |
| Baumann, D | 1 |
| Bochelen, D | 1 |
| Boumezbeur, F | 1 |
| McAllister, KH | 1 |
| Bjelke, B | 1 |
| Azcona, A | 1 |
| Lataste, X | 1 |
| Wiederhold, KH | 1 |
| Hof, RP | 1 |
1 trial available for isradipine and Anterior Choroidal Artery Infarction
| Article | Year |
|---|---|
Isradipine in patients with acute ischaemic cerebral infarction. An overview of the ASCLEPIOS Programme.
Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Calcium Channel Blockers; Cerebral Infarction; Doubl | 1990 |
6 other studies available for isradipine and Anterior Choroidal Artery Infarction
| Article | Year |
|---|---|
Failure of isradipine to reduce infarct size in mouse, gerbil, and rat models of cerebral ischemia.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Cerebral Infarction; Disease Models, Animal; Gerb | 1995 |
Failure of isradipine in cerebral ischemia models.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Gerbillinae; Isradipine; Mice; | 1996 |
Cytoprotection does not preserve brain functionality in rats during the acute post-stroke phase despite evidence of non-infarction provided by MRI.
Topics: Adenosine Triphosphate; Animals; Blood Volume; Brain; Cerebral Infarction; Cerebrovascular Circulati | 2000 |
In vivo NMR in pharmaceutical research.
Topics: Animals; Brain; Cerebral Infarction; Cerebrovascular Circulation; Drug Evaluation, Preclinical; Isra | 1992 |
Treatment of hypertension with isradipine reduces infarct size following stroke in laboratory animals.
Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Cerebral Infarction; Hypertension; Israd | 1989 |
Cerebrovascular, biochemical, and cytoprotective effects of isradipine in laboratory animals.
Topics: Animals; Antihypertensive Agents; Brain; Brain Chemistry; Brain Ischemia; Calcium Channel Blockers; | 1989 |