isradipine has been researched along with Angor Pectoris in 24 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Antihypertensive Long-term Therapy with Isradipine/Improvement of coronary flow reserve in patients with arterial and microvascular angina In patients with arterial hypertension coronary flow reserve is often impaired due to left ventricular (LV) hypertrophy and alterations of the coronary microcirculation." | 9.07 | [Long-term antihypertensive therapy with isradipine. Improvement of coronary flow reserve in patients with arterial hypertension and microvascular angina]. ( Motz, W; Strauer, BE; Vogt, M, 1994) |
| "In 21 patients with chronic stable angina pectoris stage II-III according to NYHA, by means of bicycle ergometry antianginous and antiischaemic effects of short-term dilthiazem administration (Blocalcin 60, Lachema) were compared with isradipine (Lomir, Sandoz)." | 9.06 | [Comparison of the effects of diltiazem and isradipine in patients with chronic stable angina pectoris]. ( Lupínek, Z; Meluzín, J; Novák, M; Rotrekl, P, 1989) |
| "Five hundred ninety outpatients aged 18 years or older with stable angina pectoris entered a multicenter, single-blind, nonrandomized, baseline-controlled study to assess the efficacy, safety, and tolerability of isradipine in doses of 2." | 9.06 | Safety and efficacy of isradipine, alone and in combination, in the treatment of angina pectoris. ( Nelson, DJ; Rüegg, PC, 1989) |
| "Thirty-six patients with chronic, stable angina pectoris were studied during 2-week treatment periods in which they received, in a randomized double-blind, crossover study, a new calcium entry blocking agent, isradipine, 7." | 9.06 | Efficacy of the calcium antagonist isradipine in angina pectoris. ( Bernstein, V; Enjalbert, M; Parker, JO, 1988) |
| " A MEDLINE search was conducted using the following indexing terms: isradipine, calcium-channel blockers, hypertension, and angina pectoris." | 8.78 | Isradipine--another calcium-channel blocker for the treatment of hypertension and angina. ( Lopez, LM; Santiago, TM, 1992) |
| "The primary purpose of this study was to determine whether treatment with isradipine would prevent an exercise-induced increase in the concentration of anuclear carcasses of endothelial cells in the blood of men with angina pectoris." | 7.69 | Prevention of exercise-induced endothelemia by isradipine in men with angina pectoris. ( Davis, JW; Francis-Oliver, A; Lewis, HD, 1994) |
| "ISR and DIL, at the above dosage have showed an important and significant anti-ischemic effect (IT = +41." | 6.67 | [Isradipine versus diltiazem in the treatment of stable effort angina pectoris: ergometric evaluation in a crossover double-blind study]. ( Borelli, DA; Caristo, S; Costa, R; Maio, R; Mattioli, PL; Perticone, F; Pugliese, F; Torchia, L, 1994) |
| "Isradipine is an approved antihypertensive agent, but its antianginal effects have not been well documented." | 6.67 | Duration of effects of isradipine during twice daily therapy in angina pectoris. ( Archer, S; Chrysant, S; Copen, D; Giles, T; Gorwit, J; Hobbs, S; Iteld, B; Singh, S; Thadani, U; Wakeford, C, 1994) |
| " Dose-response comparisons against nifedipine in 21 patients and against isosorbide dinitrate in 14 patients demonstrate that PN 200-110 has a similar antianginal efficacy profile to both drugs." | 6.66 | Efficacy of a new calcium antagonist PN 200-110 (isradipine) in angina pectoris. ( Allen, J; Jackson, NC; Pool, PE; Taylor, SH, 1987) |
| "The chemistry, pharmacology, pharmacokinetics, clinical uses, adverse effects, and dosage of felodipine and isradipine are reviewed." | 6.38 | Felodipine and isradipine: new calcium-channel-blocking agents for the treatment of hypertension. ( Symes, LR; Walton, T, 1993) |
| "Antihypertensive Long-term Therapy with Isradipine/Improvement of coronary flow reserve in patients with arterial and microvascular angina In patients with arterial hypertension coronary flow reserve is often impaired due to left ventricular (LV) hypertrophy and alterations of the coronary microcirculation." | 5.07 | [Long-term antihypertensive therapy with isradipine. Improvement of coronary flow reserve in patients with arterial hypertension and microvascular angina]. ( Motz, W; Strauer, BE; Vogt, M, 1994) |
| "In 21 patients with chronic stable angina pectoris stage II-III according to NYHA, by means of bicycle ergometry antianginous and antiischaemic effects of short-term dilthiazem administration (Blocalcin 60, Lachema) were compared with isradipine (Lomir, Sandoz)." | 5.06 | [Comparison of the effects of diltiazem and isradipine in patients with chronic stable angina pectoris]. ( Lupínek, Z; Meluzín, J; Novák, M; Rotrekl, P, 1989) |
| "Five hundred ninety outpatients aged 18 years or older with stable angina pectoris entered a multicenter, single-blind, nonrandomized, baseline-controlled study to assess the efficacy, safety, and tolerability of isradipine in doses of 2." | 5.06 | Safety and efficacy of isradipine, alone and in combination, in the treatment of angina pectoris. ( Nelson, DJ; Rüegg, PC, 1989) |
| "Thirty-six patients with chronic, stable angina pectoris were studied during 2-week treatment periods in which they received, in a randomized double-blind, crossover study, a new calcium entry blocking agent, isradipine, 7." | 5.06 | Efficacy of the calcium antagonist isradipine in angina pectoris. ( Bernstein, V; Enjalbert, M; Parker, JO, 1988) |
| " A MEDLINE search was conducted using the following indexing terms: isradipine, calcium-channel blockers, hypertension, and angina pectoris." | 4.78 | Isradipine--another calcium-channel blocker for the treatment of hypertension and angina. ( Lopez, LM; Santiago, TM, 1992) |
| "Isradipine is a potent dihydropyridine calcium channel blocker." | 3.77 | Isradipine. ( Schachter, M, 1991) |
| "The primary purpose of this study was to determine whether treatment with isradipine would prevent an exercise-induced increase in the concentration of anuclear carcasses of endothelial cells in the blood of men with angina pectoris." | 3.69 | Prevention of exercise-induced endothelemia by isradipine in men with angina pectoris. ( Davis, JW; Francis-Oliver, A; Lewis, HD, 1994) |
| "ISR and DIL, at the above dosage have showed an important and significant anti-ischemic effect (IT = +41." | 2.67 | [Isradipine versus diltiazem in the treatment of stable effort angina pectoris: ergometric evaluation in a crossover double-blind study]. ( Borelli, DA; Caristo, S; Costa, R; Maio, R; Mattioli, PL; Perticone, F; Pugliese, F; Torchia, L, 1994) |
| "Isradipine is an approved antihypertensive agent, but its antianginal effects have not been well documented." | 2.67 | Duration of effects of isradipine during twice daily therapy in angina pectoris. ( Archer, S; Chrysant, S; Copen, D; Giles, T; Gorwit, J; Hobbs, S; Iteld, B; Singh, S; Thadani, U; Wakeford, C, 1994) |
| "isradipine was administered in increasing doses of 2." | 2.67 | [The treatment of chronic stable angina with isradipine. A cooperative Latin American study]. ( Alcocer, L; Arcos, R; Buzzi, A; Espinoza, J; Gómez, G; Kuster, F; Mayorga, E; Román, O; Romero, C; Tavella, N, 1991) |
| "Isradipine has favourable effects comparable with those of nifedipine in patients with chronic stable angina and can be safely administered in these patients." | 2.67 | Effects of the calcium antagonist, isradipine, and nifedipine on resting and exercise haemodynamics and the neurohumoral system in patients with stable chronic angina. ( Burger, KJ; Kornecki, P; Mitrovic, V; Rieckmann, C; Schlepper, M; Welzel, D, 1990) |
| " Dose-response comparisons against nifedipine in 21 patients and against isosorbide dinitrate in 14 patients demonstrate that PN 200-110 has a similar antianginal efficacy profile to both drugs." | 2.66 | Efficacy of a new calcium antagonist PN 200-110 (isradipine) in angina pectoris. ( Allen, J; Jackson, NC; Pool, PE; Taylor, SH, 1987) |
| " Patients received 5 mg nifedipine three times a day rising to 20 mg three times a day in three dosage increments over six weeks or 2." | 2.66 | Comparison of isradipine and nifedipine in chronic stable angina. ( Handler, CE; Najm, Y; Rosenthal, E; Tsagadopoulos, D, 1988) |
| " The drugs were infused intravenously within 30 min in a dosage which led to a comparable afterload reduction (nifedipine [N] 2 mg, isradipine [I] 0." | 2.66 | [Isradipine (PN 200-110), a new dihydropyridine calcium antagonist with slight negative inotropic properties in comparison with nifedipine]. ( Karsch, KR; Mauser, M; Voelker, W, 1988) |
| "The chemistry, pharmacology, pharmacokinetics, clinical uses, adverse effects, and dosage of felodipine and isradipine are reviewed." | 2.38 | Felodipine and isradipine: new calcium-channel-blocking agents for the treatment of hypertension. ( Symes, LR; Walton, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (33.33) | 18.7374 |
| 1990's | 16 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Handler, CE | 2 |
| Sowton, E | 1 |
| Wout van den Toren, E | 1 |
| de Vries, RJ | 1 |
| Portegies, MC | 1 |
| Blanksma, PK | 1 |
| van Gilst, WH | 1 |
| Hillege, HJ | 1 |
| van Veldhuisen, DJ | 1 |
| Lie, KI | 1 |
| Perticone, F | 1 |
| Borelli, DA | 1 |
| Maio, R | 1 |
| Costa, R | 1 |
| Pugliese, F | 1 |
| Torchia, L | 1 |
| Caristo, S | 1 |
| Mattioli, PL | 1 |
| Vogt, M | 1 |
| Motz, W | 1 |
| Strauer, BE | 1 |
| Thadani, U | 1 |
| Chrysant, S | 1 |
| Gorwit, J | 1 |
| Giles, T | 1 |
| Archer, S | 1 |
| Iteld, B | 1 |
| Singh, S | 1 |
| Copen, D | 1 |
| Wakeford, C | 1 |
| Hobbs, S | 1 |
| Davis, JW | 1 |
| Lewis, HD | 1 |
| Francis-Oliver, A | 1 |
| Walton, T | 1 |
| Symes, LR | 1 |
| Doat, M | 1 |
| Hacot, JP | 1 |
| Pavin, D | 1 |
| Righetti, A | 2 |
| Maher, MJ | 1 |
| Dworkin, LD | 1 |
| Meluzín, J | 2 |
| Novák, M | 2 |
| Delonca, J | 1 |
| Kipfer, P | 1 |
| Lopez, LM | 1 |
| Santiago, TM | 1 |
| Vainer, J | 1 |
| Mádle, A | 1 |
| Cepelák, V | 1 |
| Brunát, J | 1 |
| Smíd, J | 1 |
| Román, O | 1 |
| Alcocer, L | 1 |
| Espinoza, J | 1 |
| Arcos, R | 1 |
| Gómez, G | 1 |
| Mayorga, E | 1 |
| Buzzi, A | 1 |
| Tavella, N | 1 |
| Romero, C | 1 |
| Kuster, F | 1 |
| Schachter, M | 1 |
| Currie, P | 1 |
| Saltissi, S | 1 |
| Mitrovic, V | 1 |
| Rieckmann, C | 1 |
| Kornecki, P | 1 |
| Burger, KJ | 1 |
| Welzel, D | 1 |
| Schlepper, M | 1 |
| Burger, W | 1 |
| Neidel, S | 1 |
| Kober, G | 1 |
| Lupínek, Z | 1 |
| Rotrekl, P | 1 |
| Rüegg, PC | 1 |
| Nelson, DJ | 1 |
| Taylor, SH | 1 |
| Jackson, NC | 1 |
| Allen, J | 1 |
| Pool, PE | 1 |
| Rosenthal, E | 1 |
| Tsagadopoulos, D | 1 |
| Najm, Y | 1 |
| Mauser, M | 1 |
| Voelker, W | 1 |
| Karsch, KR | 1 |
| Parker, JO | 1 |
| Enjalbert, M | 1 |
| Bernstein, V | 1 |
4 reviews available for isradipine and Angor Pectoris
| Article | Year |
|---|---|
Felodipine and isradipine: new calcium-channel-blocking agents for the treatment of hypertension.
Topics: Angina Pectoris; Animals; Drug Interactions; Felodipine; Heart Failure; Hemodynamics; Humans; Hypert | 1993 |
Calcium antagonists in the treatment of hypertension: special clinical considerations.
Topics: Angina Pectoris; Angina, Unstable; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; | 1996 |
Isradipine--another calcium-channel blocker for the treatment of hypertension and angina.
Topics: Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Dihydropyridi | 1992 |
Isradipine.
Topics: Angina Pectoris; Animals; Antihypertensive Agents; Arteriosclerosis; Calcium Channel Blockers; Human | 1991 |
19 trials available for isradipine and Angor Pectoris
| Article | Year |
|---|---|
Safety, tolerability and efficacy of PN 200-110, a new calcium antagonist in patients with angina and coronary heart disease.
Topics: Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Diseas | 1984 |
Effect of isradipine and nifedipine on diastolic function in patients with left ventricular dysfunction due to coronary artery disease: a randomized, double-blind, nuclear, stethoscope study.
Topics: Adult; Aged; Angina Pectoris; Atrial Function, Right; Cardiac Pacing, Artificial; Diastole; Double-B | 1994 |
[Isradipine versus diltiazem in the treatment of stable effort angina pectoris: ergometric evaluation in a crossover double-blind study].
Topics: Aged; Angina Pectoris; Cross-Over Studies; Diltiazem; Double-Blind Method; Electrocardiography; Exer | 1994 |
[Long-term antihypertensive therapy with isradipine. Improvement of coronary flow reserve in patients with arterial hypertension and microvascular angina].
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Coronary Angiography; Coronary Circulation; Echocar | 1994 |
Duration of effects of isradipine during twice daily therapy in angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Chemistry, Pharmaceutical; Double-Blind Method; Drug Administration Sc | 1994 |
Cardiac function improvement 24 hours after isradipine SRO in patients with chronic stable angina: a double-blind randomized study.
Topics: Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Double-Blind Method; Exercise Test; Exercise | 1996 |
[Comparison of the effects of diltiazem and isradipine in adrenergic beta receptor blockade in patients with stable angina pectoris].
Topics: Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Double-Blind Me | 1992 |
Effects of oral isradipine on left ventricular function at rest and during exercise in patients with stable chronic angina: a double-blind, placebo-controlled crossover study.
Topics: Adult; Aged; Angina Pectoris; Angiocardiography; Blood Pressure; Calcium Channel Blockers; Dihydropy | 1992 |
[The treatment of chronic stable angina with isradipine. A cooperative Latin American study].
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Dose-Res | 1991 |
Isradipine.
Topics: Angina Pectoris; Animals; Antihypertensive Agents; Arteriosclerosis; Calcium Channel Blockers; Human | 1991 |
Isradipine therapy in chronic stable angina pectoris--comparison with nifedipine.
Topics: Activities of Daily Living; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Double-Blind Met | 1991 |
Effects of the calcium antagonist, isradipine, and nifedipine on resting and exercise haemodynamics and the neurohumoral system in patients with stable chronic angina.
Topics: Angina Pectoris; Calcium Channel Blockers; Double-Blind Method; Epinephrine; Exercise Test; Hemodyna | 1990 |
Hemodynamic and antianginal effects during rest and exercise of intravenous isradipine, a new dihydropyridine calcium antagonist.
Topics: Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Electrocardiography; Exercise Test; | 1989 |
[Comparison of the effects of diltiazem and isradipine in patients with chronic stable angina pectoris].
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Diltiazem; Exercise Test; Fe | 1989 |
Safety and efficacy of isradipine, alone and in combination, in the treatment of angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Drug Combin | 1989 |
Efficacy of a new calcium antagonist PN 200-110 (isradipine) in angina pectoris.
Topics: Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Exercise T | 1987 |
Comparison of isradipine and nifedipine in chronic stable angina.
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Double- | 1988 |
[Isradipine (PN 200-110), a new dihydropyridine calcium antagonist with slight negative inotropic properties in comparison with nifedipine].
Topics: Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Heart Rate; Hemodynamic | 1988 |
Efficacy of the calcium antagonist isradipine in angina pectoris.
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Double-Blind Method; Humans; Isradipine; Middle Age | 1988 |
2 other studies available for isradipine and Angor Pectoris
| Article | Year |
|---|---|
Prevention of exercise-induced endothelemia by isradipine in men with angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Cell Count; Data Interpretation, Statistical; Endothelium, Vascular; E | 1994 |
[The effect of isradipine (Lomir, Sandoz) on coronary insufficiency during the esophageal stimulation stress test].
Topics: Aged; Angina Pectoris; Calcium Channel Blockers; Cardiac Pacing, Artificial; Electrocardiography; Fe | 1991 |