isradipine has been researched along with Acute Confusional Senile Dementia in 7 studies
Isradipine: A potent antagonist of CALCIUM CHANNELS that is highly selective for VASCULAR SMOOTH MUSCLE. It is effective in the treatment of chronic stable angina pectoris, hypertension, and congestive cardiac failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Isradipine is a Federal Drug Administration-approved dihydropyridine calcium channel blocker that binds selectively to Ca(v)1." | 2.47 | Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: the case for isradipine. ( Anekonda, TS; Quinn, JF, 2011) |
| "Isradipine was the most potent blocker, preventing APP CTF neurotoxicity at nanomolar concentrations." | 1.37 | L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimer's disease. ( Anekonda, TS; Frahler, K; Harris, C; Quinn, JF; Wadsworth, TL; Woltjer, RL, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Wickline, JL | 1 |
| Smith, S | 1 |
| Shin, R | 1 |
| Odfalk, K | 1 |
| Sanchez, J | 1 |
| Javors, M | 1 |
| Ginsburg, B | 1 |
| Hopp, SC | 1 |
| Gholami Pourbadie, H | 1 |
| Naderi, N | 1 |
| Janahmadi, M | 1 |
| Mehranfard, N | 1 |
| Motamedi, F | 1 |
| Anekonda, TS | 3 |
| Quinn, JF | 3 |
| Harris, C | 1 |
| Frahler, K | 1 |
| Wadsworth, TL | 2 |
| Woltjer, RL | 2 |
| Copenhaver, PF | 1 |
| Musashe, D | 1 |
| Robinson, KM | 1 |
| Ramaker, JM | 1 |
| Swanson, TL | 1 |
| Kretzschmar, D | 1 |
| Sen, AP | 1 |
| Boksa, P | 1 |
| Quirion, R | 1 |
| Ikeda, M | 1 |
| Dewar, D | 1 |
| McCulloch, J | 1 |
1 review available for isradipine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Calcium channel blocking as a therapeutic strategy for Alzheimer's disease: the case for isradipine.
Topics: Alzheimer Disease; Animals; Autophagy; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; | 2011 |
6 other studies available for isradipine and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
L-type calcium channel antagonist isradipine age-dependently decreases plaque associated dystrophic neurites in 5XFAD mouse model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Calcium Channel B | 2023 |
Calcium channel blockade attenuates abnormal synaptic transmission in the dentate gyrus elicited by entorhinal amyloidopathy.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcium Channel Blockers; Dentate Gyrus; Entorhin | 2016 |
L-type voltage-gated calcium channel blockade with isradipine as a therapeutic strategy for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Fe | 2011 |
A translational continuum of model systems for evaluating treatment strategies in Alzheimer's disease: isradipine as a candidate drug.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Biological Assay; Calcium Channels, L-Type; Cell | 2011 |
Brain calcium channel related dihydropyridine and phenylalkylamine binding sites in Alzheimer's, Parkinson's and Huntington's diseases.
Topics: Aged; Alzheimer Disease; Autopsy; Binding Sites; Brain; Calcium; Calcium Channels; Dihydropyridines; | 1993 |
A correlative study of calcium channel antagonist binding and local neuropathological features in the hippocampus in Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Calcium Channels; Choline O-Acetyltransferase; Female; H | 1992 |