isoxsuprine has been researched along with Necrosis in 12 studies
Isoxsuprine: A beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplying skin. It is used in the treatment of peripheral vascular disease and in premature labor.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a controlled study of the rat abdominal pedicle flap the area of flap necrosis was not reduced by a course of treatment with isoxsuprine." | 5.05 | Isoxsuprine and the rat abdominal pedicle flap: a controlled study. ( Griffiths, RW; Humphries, NL, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Costa, W | 1 |
| Silva, AL | 1 |
| Costa, GR | 1 |
| Vidigal, PV | 1 |
| Pereira, FH | 1 |
| Wray, RC | 1 |
| Young, VL | 1 |
| Griffiths, RW | 1 |
| Humphries, NL | 1 |
| Hillelson, RL | 1 |
| Glowacki, J | 1 |
| Healey, NA | 1 |
| Mulliken, JB | 1 |
| Zide, B | 1 |
| Buncke, HJ | 1 |
| Finseth, F | 6 |
| Quirinia, A | 1 |
| Gottrup, F | 1 |
| Viidik, A | 1 |
| Adelberg, MG | 2 |
| Myers, MB | 1 |
| Zimmermann, J | 2 |
| Liggins, D | 1 |
1 trial available for isoxsuprine and Necrosis
| Article | Year |
|---|---|
Isoxsuprine and the rat abdominal pedicle flap: a controlled study.
Topics: Animals; Body Weight; Clinical Trials as Topic; Graft Survival; Isoxsuprine; Male; Necrosis; Rats; R | 1981 |
11 other studies available for isoxsuprine and Necrosis
| Article | Year |
|---|---|
Analysis of effect isoxsuprine hydrochloride and nicotine in the Transverse Rectus Abdominis Myocutaneous flap (TRAM) in rats.
Topics: Animals; Female; Graft Survival; Isoxsuprine; Models, Animal; Myocutaneous Flap; Necrosis; Nicotine; | 2015 |
Drug treatment and flap survival.
Topics: Administration, Oral; Animals; Drug Evaluation; Graft Survival; Heparin; Infusions, Parenteral; Isox | 1984 |
A microangiographic study of hematoma-associated flap necrosis and salvage with isoxsuprine.
Topics: Angiography; Animals; Graft Survival; Hematoma; Isoxsuprine; Male; Microradiography; Necrosis; Rats; | 1980 |
A study of the treatment time necessary for the vasodilator drug isoxsuprine to prevent necrosis in a skin flap.
Topics: Animals; Drug Administration Schedule; Graft Survival; Isoxsuprine; Necrosis; Postoperative Complica | 1980 |
Failure of buflomedil to improve wound healing in ischaemic skin flaps.
Topics: Adrenergic alpha-Antagonists; Animals; Ischemia; Isoxsuprine; Male; Necrosis; Pyrrolidines; Rats; Ra | 1996 |
Prevention of skin flap necrosis by a course of treatment with vasodilator drugs.
Topics: Animals; Guanethidine; Hydralazine; Isoxsuprine; Necrosis; Phenoxybenzamine; Rats; Skin; Skin Transp | 1978 |
Clinical salvage of three failing skin flaps by treatment with a vasodilator drug.
Topics: Face; Fluoresceins; Graft Survival; Humans; Isoxsuprine; Male; Middle Aged; Muscles; Necrosis; Skin; | 1979 |
Clinical salvage of three failing skin flaps by treatment with a vasodilator drug (by Frederick Finseth, M.D.). Commentary.
Topics: Animals; Fluoresceins; Humans; Isoxsuprine; Necrosis; Rats; Skin; Skin Transplantation; Transplantat | 1979 |
Experimental work with isoxuprine for prevention of skin flap necrosis and for treatment of the failing flap.
Topics: Animals; Dose-Response Relationship, Drug; Drug Therapy, Combination; Graft Rejection; Injections, I | 1979 |
Prevention of necrosis in island myocutaneous flaps in the pig by treatment with isoxsuprine.
Topics: Animals; Graft Survival; Hindlimb; Isoxsuprine; Male; Muscles; Necrosis; Skin; Skin Transplantation; | 1979 |
Prevention of muscle necrosis in an experimental neurovascular island muscle flap by a vasodilator drug--isoxsuprine.
Topics: Animals; Fluoresceins; Injections, Intraperitoneal; Isoxsuprine; Muscles; Necrosis; Rabbits; Regiona | 1979 |