Page last updated: 2024-08-21

isoxazoles and Weight Gain

isoxazoles has been researched along with Weight Gain in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (10.00)18.2507
2000's9 (30.00)29.6817
2010's17 (56.67)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Asamoah, AL; Gosal, R; Grossberg, GT; Nair, A; Salem, A1
Ballon, JS; Contreras, I; Freyberg, R; Freyberg, Z; Leibel, RL; Lieberman, JA; Mayer, LE; Pajvani, UB; Rosenbaum, M1
Ghanizadeh, A; Nikseresht, MS; Sahraian, A1
Chen, Y; Liu, BF; Liu, S; Liu, X; Qiu, Y; Wang, S; Xu, X; Yu, M; Zhang, G; Zhang, T; Zhao, S1
Quilo, CG; Rodríguez-Martínez, A1
Dai, G; Zhang, Y1
Alphs, L; Bossie, CA; Fu, DJ; Sliwa, JK; Turkoz, I1
Buckley, PF; Byerly, M; Dominik, R; Hamer, RM; Lamberti, JS; McEvoy, JP; Ray, N; Rosenheck, RA; Stroup, TS; Swartz, MS; Wilkins, TM1
Bray, GA; Gadde, KM; Shin, JH; Østbye, T1
Chung, MK; Hwang, KH; Jeong, EJ; Koo, SJ; Lee, J; Song, J; Yu, WJ1
Abou-Khalil, B; Montouris, G1
Lavedan, C; Thompson, A; Volpi, S1
Kecskés, I1
Bass, JY; Caravella, JA; Chen, L; Creech, KL; Deaton, DN; Madauss, KP; Marr, HB; McFadyen, RB; Miller, AB; Mills, WY; Navas, F; Parks, DJ; Smalley, TL; Spearing, PK; Todd, D; Williams, SP; Wisely, GB1
Case, M; Hoffmann, VP; Jacobson, JG1
Han, C; Joe, SH; Ko, YH; Lee, MS; Lim, J; Yang, J1
Citrome, L1
Guerdjikova, AI; Keck, PE; Martens, B; McCoy, J; McElroy, SL; Moeller, D; Mori, N; Winstanley, E1
Correll, CU; De Hert, M; Detraux, J; Sweers, K; van Winkel, R; Yu, W1
Gao, M; Huang, Y; Liu, D; Ma, Y; Yan, L1
Calamoneri, F; D'Arrigo, C; Gagliano, A; Germanò, E; Impallomeni, C; Pustorino, G; Spina, E1
Berger, JP; Doebber, TW; Forrest, MJ; Jones, AB; Liu, K; Macnaul, KL; Moller, DE; Xu, L; Zhou, G1
Bonde, RK; Jensen, BL; Madsen, K; Nielsen, FT; Skøtt, O; Stubbe, J1
Bymaster, FP; Cowley, MA; Gadde, KM; Krishnan, RK; Landbloom, RP; McKinney, AA; Sinnayah, P; Tollefson, GD; Wallingford, NM1
Cutler, AJ; Polymeropoulos, MH; Weiden, PJ; Wolfgang, CD1
Chong, AS; Cohn, S; Foster, PF; Kociss, K; McChesney, L; Sankary, HN; Williams, JW; Xiao, F1
Block, N; Brock, TA; Chen, SJ; Chen, YF; Dixon, RA; Munsch, CL; Sherwood, SJ; Tilton, RG; Wu, C1
duToit, DF; Lyners, R; Mattysen, J; Muller, CJ; Muller, N; Page, BJ1
Aoki, Y; Hashimoto, Y; Kiguchi, M; Kuwata, M; Okazaki, S; Shimpo, K; Takeuchi, M; Yamashita, K1
Ikebuchi, K; Katayama, S; Koida, M; Shinomiya, M; Yamakita, O; Yoshida, R1

Reviews

6 review(s) available for isoxazoles and Weight Gain

ArticleYear
An update on the efficacy and safety of iloperidone as a schizophrenia therapy.
    Expert opinion on pharmacotherapy, 2020, Volume: 21, Issue:15

    Topics: Antipsychotic Agents; Humans; Isoxazoles; Piperidines; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Schizophrenia; Weight Gain

2020
Paliperidone extended-release: safety and tolerability from a metabolic profile perspective.
    Clinical drug investigation, 2013, Volume: 33, Issue:12

    Topics: Antipsychotic Agents; Clinical Trials as Topic; Delayed-Action Preparations; Glucose; Humans; Isoxazoles; Paliperidone Palmitate; Pyrimidines; Schizophrenia; Weight Gain

2013
The first line of therapy in a girl with juvenile myoclonic epilepsy: should it be valproate or a new agent?
    Epilepsia, 2009, Volume: 50 Suppl 8

    Topics: Anticonvulsants; Congenital Abnormalities; Delayed-Action Preparations; Drug Design; Epilepsy, Generalized; Female; Fructose; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Male; Myoclonic Epilepsy, Juvenile; Piracetam; Pregnancy; Risk Assessment; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Weight Gain; Zonisamide

2009
Iloperidone: a clinical overview.
    The Journal of clinical psychiatry, 2011, Volume: 72 Suppl 1

    Topics: Antipsychotic Agents; Electrocardiography; Heart Rate; Humans; Isoxazoles; Long QT Syndrome; Piperidines; Schizophrenia; Treatment Outcome; Weight Gain

2011
Body weight and metabolic adverse effects of asenapine, iloperidone, lurasidone and paliperidone in the treatment of schizophrenia and bipolar disorder: a systematic review and exploratory meta-analysis.
    CNS drugs, 2012, Sep-01, Volume: 26, Issue:9

    Topics: Antipsychotic Agents; Bipolar Disorder; Blood Glucose; Dibenzocycloheptenes; Heterocyclic Compounds, 4 or More Rings; Humans; Isoindoles; Isoxazoles; Lipid Metabolism; Lurasidone Hydrochloride; Paliperidone Palmitate; Piperidines; Pyrimidines; Randomized Controlled Trials as Topic; Schizophrenia; Thiazoles; Weight Gain

2012
Safety profile of iloperidone: a pooled analysis of 6-week acute-phase pivotal trials.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:2 Suppl 1

    Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Basal Ganglia Diseases; Double-Blind Method; Female; Humans; Isoxazoles; Long QT Syndrome; Male; Middle Aged; Patient Dropouts; Piperidines; Prospective Studies; Psychotic Disorders; Randomized Controlled Trials as Topic; Schizophrenia; Weight Gain

2008

Trials

10 trial(s) available for isoxazoles and Weight Gain

ArticleYear
Pathophysiology of drug induced weight and metabolic effects: findings from an RCT in healthy volunteers treated with olanzapine, iloperidone, or placebo.
    Journal of psychopharmacology (Oxford, England), 2018, Volume: 32, Issue:5

    Topics: Adolescent; Adult; Antipsychotic Agents; Blood Glucose; Body Weight; Double-Blind Method; Dyslipidemias; Eating; Energy Metabolism; Female; Glucose Tolerance Test; Healthy Volunteers; Humans; Insulin; Insulin Resistance; Isoxazoles; Lipids; Male; Obesity; Olanzapine; Piperidines; Weight Gain; Young Adult

2018
The effect of zonisamide on antipsychotic-associated weight gain in patients with schizophrenia: a randomized, double-blind, placebo-controlled clinical trial.
    Schizophrenia research, 2013, Volume: 147, Issue:1

    Topics: Adult; Antipsychotic Agents; Body Mass Index; Double-Blind Method; Female; Follow-Up Studies; Humans; Isoxazoles; Male; Obesity; Schizophrenia; Statistics, Nonparametric; Treatment Outcome; Waist Circumference; Weight Gain; Young Adult; Zonisamide

2013
Efficacy and metabolic influence of paliperidone ER, aripiprazole and ziprasidone to patients with first-episode schizophrenia through 52 weeks follow-up in China.
    Human psychopharmacology, 2012, Volume: 27, Issue:6

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Body Mass Index; China; Delayed-Action Preparations; Diagnostic and Statistical Manual of Mental Disorders; Female; Follow-Up Studies; Humans; Hyperglycemia; Hyperlipidemias; Isoxazoles; Male; Metabolic Diseases; Paliperidone Palmitate; Piperazines; Psychiatric Status Rating Scales; Pyrimidines; Quinolones; Schizophrenia; Thiazoles; Weight Gain; Young Adult

2012
Body mass index and metabolic parameters in patients with schizophrenia during long-term treatment with paliperidone palmitate.
    BMC psychiatry, 2014, Feb-22, Volume: 14

    Topics: Adult; Antipsychotic Agents; Blood Glucose; Body Mass Index; Body Weight; Double-Blind Method; Female; Humans; Isoxazoles; Lipids; Male; Middle Aged; Obesity; Paliperidone Palmitate; Palmitates; Schizophrenia; Weight Gain; Young Adult

2014
Effectiveness of paliperidone palmitate vs haloperidol decanoate for maintenance treatment of schizophrenia: a randomized clinical trial.
    JAMA, 2014, May-21, Volume: 311, Issue:19

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Double-Blind Method; Female; Haloperidol; Hospitalization; Humans; Injections, Intramuscular; Isoxazoles; Male; Middle Aged; Paliperidone Palmitate; Palmitates; Schizophrenia; Treatment Failure; Treatment Outcome; Weight Gain

2014
Weight changes in obese adults 6-months after discontinuation of double-blind zonisamide or placebo treatment.
    Diabetes, obesity & metabolism, 2014, Volume: 16, Issue:8

    Topics: Adult; Anti-Obesity Agents; Anticonvulsants; Body Mass Index; Cohort Studies; Combined Modality Therapy; Diet, Reducing; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Isoxazoles; Life Style; Male; Middle Aged; North Carolina; Obesity; Patient Compliance; Patient Education as Topic; Weight Gain; Zonisamide

2014
Absence of weight gain association with the HTR2C -759C/T polymorphism in patients with schizophrenia treated with iloperidone.
    Psychiatry research, 2010, Feb-28, Volume: 175, Issue:3

    Topics: Analysis of Variance; Antipsychotic Agents; Female; Follow-Up Studies; Gene Frequency; Genotype; Humans; Isoxazoles; Male; Piperazines; Piperidines; Polymorphism, Genetic; Receptor, Serotonin, 5-HT2C; Schizophrenia; Thiazoles; Weight Gain

2010
Assessment of treatment algorithms including amantadine, metformin, and zonisamide for the prevention of weight gain with olanzapine: a randomized controlled open-label study.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:2

    Topics: Adolescent; Adult; Aged; Algorithms; Amantadine; Antipsychotic Agents; Benzodiazepines; Clinical Protocols; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Metformin; Middle Aged; Olanzapine; Psychotic Disorders; Schizophrenia; Weight Gain; Zonisamide

2012
A randomized, placebo-controlled study of zonisamide to prevent olanzapine-associated weight gain.
    Journal of clinical psychopharmacology, 2012, Volume: 32, Issue:2

    Topics: Adult; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Cognition Disorders; Double-Blind Method; Female; Follow-Up Studies; Humans; Isoxazoles; Male; Middle Aged; Olanzapine; Regression Analysis; Schizophrenia; Treatment Outcome; Weight Gain; Young Adult; Zonisamide

2012
Risperidone treatment of children with autistic disorder: effectiveness, tolerability, and pharmacokinetic implications.
    Journal of child and adolescent psychopharmacology, 2004,Spring, Volume: 14, Issue:1

    Topics: Autistic Disorder; Child; Child, Preschool; Drug Tolerance; Female; Humans; Isoxazoles; Male; Paliperidone Palmitate; Pyrimidines; Risperidone; Statistics, Nonparametric; Weight Gain

2004

Other Studies

14 other study(ies) available for isoxazoles and Weight Gain

ArticleYear
Synthesis and biological investigation of coumarin piperazine (piperidine) derivatives as potential multireceptor atypical antipsychotics.
    Journal of medicinal chemistry, 2013, Jun-13, Volume: 56, Issue:11

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Biological Availability; Coumarins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; In Vitro Techniques; Isoxazoles; Lethal Dose 50; Mice; Motor Activity; Prolactin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Dopamine D3; Structure-Activity Relationship; Weight Gain

2013
Developmental toxicity assessment of the new turf herbicide, methiozolin ([5-(2,6-difluorobenzyl)oxymethyl-5-methyl-3,3(3-methylthiophen-2-yl)-1,2-isoxazoline]), in rabbits.
    Regulatory toxicology and pharmacology : RTP, 2015, Volume: 72, Issue:3

    Topics: Animals; Body Weight; Female; Herbicides; Isoxazoles; Male; No-Observed-Adverse-Effect Level; Pregnancy; Pregnancy Outcome; Rabbits; Thiophenes; Weight Gain

2015
[Successful quetiapine therapy in psychotic patients with mood elevation].
    Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology, 2009, Volume: 11, Issue:4

    Topics: Adult; Affect; Antipsychotic Agents; Dibenzothiazepines; Drug Therapy, Combination; Euphoria; Female; Humans; Isoxazoles; Male; Medication Adherence; Middle Aged; Paliperidone Palmitate; Prolactin; Psychotic Disorders; Pyrimidines; Quetiapine Fumarate; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; Weight Gain

2009
Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene.
    Bioorganic & medicinal chemistry letters, 2011, Feb-15, Volume: 21, Issue:4

    Topics: Animals; Binding Sites; Blood Glucose; Crystallography, X-Ray; Diabetes Mellitus, Experimental; Dogs; Fluorescence Resonance Energy Transfer; Humans; Isoxazoles; Ligands; Mice; Molecular Conformation; Naphthalenes; Protein Structure, Tertiary; Quinolines; Rats; Receptors, Cytoplasmic and Nuclear; Weight Gain

2011
Zonisamide produces weight loss in psychotropic drug-treated psychiatric outpatients.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Dec-01, Volume: 35, Issue:8

    Topics: Adult; Female; Humans; Isoxazoles; Male; Mental Disorders; Middle Aged; Outpatients; Overweight; Psychotropic Drugs; Severity of Illness Index; Treatment Outcome; Weight Gain; Weight Loss; Zonisamide

2011
Synthetic FXR agonist GW4064 prevents diet-induced hepatic steatosis and insulin resistance.
    Pharmaceutical research, 2013, Volume: 30, Issue:5

    Topics: Animals; CD36 Antigens; Cell Line; Diet, High-Fat; Fatty Liver; Gene Expression Regulation; Isoxazoles; Lipid Metabolism; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Receptors, Cytoplasmic and Nuclear; Weight Gain

2013
Discovery of a novel series of peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes and dyslipidemia.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: 3T3-L1 Cells; Animals; Blood Glucose; Carrier Proteins; Chlorocebus aethiops; Cholesterol; COS Cells; Diabetes Mellitus, Type 2; Dogs; Fatty Acid-Binding Proteins; Humans; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Isoxazoles; Mice; Mice, Obese; PPAR alpha; PPAR gamma; Propionates; Radioligand Assay; RNA, Messenger; Structure-Activity Relationship; Transcriptional Activation; Triglycerides; Weight Gain

2005
Postnatal adrenalectomy impairs urinary concentrating ability by increased COX-2 and leads to renal medullary injury.
    American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Animals; Corticosterone; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Isoxazoles; Kidney Medulla; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride; Urine; Weight Gain

2007
Zonisamide prevents olanzapine-associated hyperphagia, weight gain, and elevated blood glucose in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:12

    Topics: Animals; Anticonvulsants; Appetite Regulation; Benzodiazepines; Biomarkers; Body Weight; Diabetes Mellitus; Female; Hyperglycemia; Hyperphagia; Hypothalamic Area, Lateral; Intracellular Signaling Peptides and Proteins; Isoxazoles; Neurons; Neuropeptides; Nucleus Accumbens; Obesity; Olanzapine; Orexins; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Weight Gain; Zonisamide

2008
Leflunomide immunosuppression in rat small intestinal transplantation.
    Transplantation proceedings, 1994, Volume: 26, Issue:3

    Topics: Animals; Graft Rejection; Graft Survival; Graft vs Host Disease; Immunosuppressive Agents; Intestine, Small; Isoxazoles; Leflunomide; Rats; Rats, Inbred Lew; Transplantation, Homologous; Weight Gain

1994
Attenuation of pulmonary vascular hypertension and cardiac hypertrophy with sitaxsentan sodium, an orally active ET(A) receptor antagonist.
    Pulmonary pharmacology & therapeutics, 2000, Volume: 13, Issue:2

    Topics: Animals; Cardiomegaly; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Hypertension, Pulmonary; Hypertrophy; Hypoxia; Isoxazoles; Male; Monocrotaline; Oxygen; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Thiophenes; Vasoconstriction; Weight Gain

2000
Efficacy of malononitrilamide 715 as immunosuppressant, alone or in combination with cyclosporin, in allogeneic foetal rat pancreatic transplantation.
    Transplantation proceedings, 2001, Volume: 33, Issue:3

    Topics: Alkynes; Animals; Cyclosporine; Drug Therapy, Combination; Fetal Tissue Transplantation; Immunosuppressive Agents; Isoxazoles; Nitriles; Pancreas Transplantation; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Subrenal Capsule Assay; T-Lymphocytes; Transplantation, Homologous; Weight Gain; Weight Loss

2001
[Three-month oral subacute toxicity study of mofezolac (N-22) in rats].
    The Journal of toxicological sciences, 1990, Volume: 15 Suppl 2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Chemical Analysis; Drinking; Eating; Erythrocyte Count; Female; Ileal Diseases; Isoxazoles; Jejunal Diseases; Male; Organ Size; Rats; Rats, Inbred Strains; Ulcer; Weight Gain

1990
[Reproductive and developmental toxicity study of mofezolac (N-22) (4)--Study by oral administration of N-22 during the perinatal and lactation periods in rats].
    The Journal of toxicological sciences, 1990, Volume: 15 Suppl 2

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Eating; Embryonic and Fetal Development; Female; Fetal Death; Isoxazoles; Lactation; Litter Size; Male; Postpartum Period; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Reproduction; Weight Gain

1990