isoxazoles has been researched along with Severe Acute Respiratory Syndrome in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, Y; Lou, Z; Rao, Z; Ren, Z; Yan, L; Yang, C; Zhang, N | 1 |
| Anand, K; Hilgenfeld, R; Mesters, JR; Wadhwani, P; Ziebuhr, J | 1 |
2 other study(ies) available for isoxazoles and Severe Acute Respiratory Syndrome
| Article | Year |
|---|---|
The newly emerged SARS-like coronavirus HCoV-EMC also has an "Achilles' heel": current effective inhibitor targeting a 3C-like protease.
Topics: Binding Sites; Coronavirus 3C Proteases; Cysteine Endopeptidases; Humans; Isoxazoles; Phenylalanine; Protease Inhibitors; Protein Structure, Tertiary; Pyrrolidinones; Rhinovirus; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; Valine; Viral Proteins | 2013 |
Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Antiviral Agents; Binding Sites; Catalytic Domain; Coronavirus 229E, Human; Coronavirus 3C Proteases; Crystallization; Crystallography, X-Ray; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dimerization; Drug Design; Humans; Isoxazoles; Models, Molecular; Molecular Sequence Data; Phenylalanine; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrrolidinones; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; Transmissible gastroenteritis virus; Valine | 2003 |