Page last updated: 2024-08-21

isoxazoles and Sclerosis, Systemic

isoxazoles has been researched along with Sclerosis, Systemic in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (42.86)29.6817
2010's8 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cantatore, FP; Corrado, A; Costantino, E; Foschino Barbaro, MP; Neve, A; Palladino, GP1
Martins-Filho, OA; Mota, LM; Oliveira, AC; Santos-Neto, LL; Simões, M; Tauil, PL1
Ohashi, T; Yamamoto, T1
Coghlan, G; Kabunga, P1
Becker, H; Domschke, W; Gaubitz, M; Mohr, M; Sunderkoetter, C; Willeke, P1
Champion, HC; Girgis, RE; Hassoun, PM; Hummers, LK; Mathai, SC; Wigley, FM; Zaiman, A1
Bellamy, CO; Dhaun, N; Kluth, DC; MacIntyre, IM1
Derk, CT; Shetty, N1
Akhmetshina, A; Allanore, Y; Avouac, J; Beyer, C; Dees, C; Distler, JH; Distler, O; Horn, A; Maurer, B; Palumbo, K; Sadowski, A; Schett, G; Schneider, H; Shiozawa, S; Tomcik, M; Zerr, P1
Hintz, E; Klein, R; Staehler, G1
Celermajer, DS; Corte, TJ; Don, GW; Joseph, F1
Brizzolara, R; Cutolo, M; Ferrone, C; Montagna, P; Parodio, A; Seriolo, B; Soldano, S; Sulli, A; Villaggio, B1
Gordeev, AV; Mutovina, ZIu; Nasankaeva, EK1
Caruso, A; Ferri, C; Giuggioli, D; Sebastiani, M; Vesprini, E1

Reviews

2 review(s) available for isoxazoles and Sclerosis, Systemic

ArticleYear
Endothelin receptor antagonism: role in the treatment of pulmonary arterial hypertension related to scleroderma.
    Drugs, 2008, Volume: 68, Issue:12

    Topics: Antihypertensive Agents; Bosentan; Drug Therapy, Combination; Endothelin Receptor Antagonists; Humans; Hypertension, Pulmonary; Isoxazoles; Phenylpropionates; Pyridazines; Receptors, Endothelin; Scleroderma, Systemic; Sulfonamides; Thiophenes; Treatment Outcome

2008
Endothelin receptor antagonists as disease modifiers in systemic sclerosis.
    Inflammation & allergy drug targets, 2011, Volume: 10, Issue:1

    Topics: Animals; Antihypertensive Agents; Bosentan; Endothelin Receptor Antagonists; Endothelins; Familial Primary Pulmonary Hypertension; Fibrosis; Humans; Hypertension, Pulmonary; Isoxazoles; Phenylpropionates; Pyridazines; Receptors, Endothelin; Scleroderma, Systemic; Sulfonamides; Thiophenes; Treatment Outcome

2011

Other Studies

12 other study(ies) available for isoxazoles and Sclerosis, Systemic

ArticleYear
Effect of endothelin inhibition on lung fibroblasts on patients with systemic sclerosis.
    Minerva medica, 2013, Volume: 104, Issue:5

    Topics: Actins; Adult; Aged; Cell Differentiation; Cell Survival; Collagen Type I; Endothelin Receptor Antagonists; Endothelins; Female; Fibroblasts; Fibronectins; Humans; Isoxazoles; Lung; Male; Middle Aged; Muscle, Smooth; Myofibroblasts; Scleroderma, Systemic; Thiophenes; Vascular Endothelial Growth Factor A

2013
Seroconversion in patients with rheumatic diseases treated with immunomodulators or immunosuppressants, who were inadvertently revaccinated against yellow fever.
    Arthritis & rheumatology (Hoboken, N.J.), 2015, Volume: 67, Issue:2

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Arthritis, Rheumatoid; Brazil; Child; Contraindications; Female; Humans; Immunity, Innate; Immunization, Secondary; Immunologic Factors; Immunosuppressive Agents; Infliximab; Isoxazoles; Leflunomide; Lupus Erythematosus, Systemic; Middle Aged; Retrospective Studies; Rheumatic Diseases; Rituximab; Scleroderma, Systemic; Yellow Fever; Yellow Fever Vaccine; Young Adult

2015
Antifibrotic effect of lysophosphatidic acid receptors LPA1 and LPA3 antagonist on experimental murine scleroderma induced by bleomycin.
    Experimental dermatology, 2015, Volume: 24, Issue:9

    Topics: Animals; Bleomycin; Cell Count; Chemokine CCL3; Collagen Type I; Connective Tissue Growth Factor; Disease Models, Animal; Female; Fibrosis; Hydroxyproline; Interferon-gamma; Isoxazoles; Lung; Mast Cells; Mice; Propionates; Receptors, Lysophosphatidic Acid; RNA, Messenger; Scleroderma, Systemic; Skin; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1

2015
[Leg ulcer in mixed connective tissue disease. Resolution during sitaxsentan therapy].
    Zeitschrift fur Rheumatologie, 2009, Volume: 68, Issue:2

    Topics: Adult; Antihypertensive Agents; Female; Humans; Isoxazoles; Leg Ulcer; Raynaud Disease; Scleroderma, Systemic; Thiophenes; Treatment Outcome

2009
Survival in pulmonary hypertension associated with the scleroderma spectrum of diseases: impact of interstitial lung disease.
    Arthritis and rheumatism, 2009, Volume: 60, Issue:2

    Topics: Bosentan; Cohort Studies; Comorbidity; Endothelin Receptor Antagonists; Female; Follow-Up Studies; Humans; Hypertension, Pulmonary; Isoxazoles; Lung Diseases, Interstitial; Male; Maryland; Middle Aged; Piperazines; Prognosis; Proportional Hazards Models; Purines; Receptors, Endothelin; Scleroderma, Diffuse; Scleroderma, Systemic; Sildenafil Citrate; Sulfonamides; Sulfones; Survival Rate; Thiophenes; Vasodilator Agents

2009
Endothelin receptor antagonism and renin inhibition as treatment options for scleroderma kidney.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 54, Issue:4

    Topics: Amides; Antihypertensive Agents; Atrophy; Biomarkers; Biopsy; Endothelin Receptor Antagonists; Female; Fibrosis; Fumarates; Humans; Hypertension, Renal; Isoxazoles; Kidney; Middle Aged; Proteinuria; Pulmonary Fibrosis; Renal Insufficiency, Chronic; Renin; Scleroderma, Systemic; Thiophenes; Treatment Outcome

2009
Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis.
    Arthritis and rheumatism, 2012, Volume: 64, Issue:5

    Topics: Animals; Benzophenones; Bleomycin; Cells, Cultured; Collagen; Disease Models, Animal; Female; Fibroblasts; Fibrosis; Gene Expression; Humans; Isoxazoles; JNK Mitogen-Activated Protein Kinases; Male; Mice; Proto-Oncogene Proteins c-fos; RNA, Small Interfering; Scleroderma, Systemic; Signal Transduction; Transcription Factor AP-1; Transfection; Transforming Growth Factor beta; Up-Regulation

2012
Exacerbation of AIH in a patient with an AIH/systemic sclerosis overlap syndrome and pulmonary arterial hypertension treated with the endothelin-1 receptor antagonist sitaxentan.
    BMJ case reports, 2012, Jul-13, Volume: 2012

    Topics: Autoantibodies; Autoantigens; Disease Progression; Endothelin A Receptor Antagonists; Familial Primary Pulmonary Hypertension; Female; Hepatitis, Autoimmune; Humans; Hypertension, Pulmonary; Isoxazoles; Middle Aged; Scleroderma, Systemic; Thiophenes; Treatment Outcome

2012
Ironic case of hepatic dysfunction following the global withdrawal of sitaxentan.
    Internal medicine journal, 2012, Volume: 42, Issue:12

    Topics: Antihypertensive Agents; Bosentan; Endothelin Receptor Antagonists; Female; Humans; Hypertension, Pulmonary; Isoxazoles; Liver; Liver Function Tests; Middle Aged; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Safety-Based Drug Withdrawals; Scleroderma, Systemic; Sildenafil Citrate; Sulfonamides; Sulfones; Thiophenes

2012
Endothelin receptor antagonists: effects on extracellular matrix synthesis in primary cultures of skin fibroblasts from systemic sclerosis patients.
    Reumatismo, 2012, Dec-11, Volume: 64, Issue:5

    Topics: Aged; Bosentan; Cells, Cultured; Collagen Type I; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Extracellular Matrix Proteins; Female; Fibrillin-1; Fibrillins; Fibroblasts; Fibronectins; Fibrosis; Humans; Isoxazoles; Microfilament Proteins; Middle Aged; Primary Cell Culture; Scleroderma, Systemic; Sulfonamides; Thiophenes

2012
[Effective treatment of systemic sclerosis with leflunomide].
    Terapevticheskii arkhiv, 2005, Volume: 77, Issue:5

    Topics: Aged; Female; Humans; Isoxazoles; Leflunomide; Scleroderma, Systemic; Treatment Outcome

2005
Successful treatment with leflunomide of arthritis in systemic sclerosis patients.
    Rheumatology (Oxford, England), 2006, Volume: 45, Issue:9

    Topics: Adult; Antirheumatic Agents; Arthritis; Female; Humans; Isoxazoles; Leflunomide; Middle Aged; Scleroderma, Systemic

2006