isoxazoles has been researched along with Prostatic Neoplasms in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 3 (14.29) | 29.6817 |
| 2010's | 13 (61.90) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, C; Li, J; Shen, H; Wu, X; Xiang, Q; Xu, Y; Zhang, C; Zhang, M; Zhang, Y; Zhao, L; Zhu, R; Zhuang, X | 1 |
| Liu, ZX; Wang, C; Wu, C; Wu, TB; Xiang, QP; Xiao, LJ; Xu, Y; Zhang, C; Zhang, MF; Zhang, Y | 1 |
| Armstrong, HK; Brooks, DA; Butler, LM; Centenera, MM; Chin, MY; Gillis, JL; Johnson, IRD; Levrier, C; Lynn, DJ; Moldovan, M; Nassar, ZD; Sadowski, MC; Selth, LA; Tarulli, G; Tomlinson Guns, ES | 1 |
| Cronauer, M; Taubert, H; Wach, S | 1 |
| Bilen, CY; Dikmen, AU; Kiliccioglu, I; Konac, E; Sozen, S | 1 |
| Honkakoski, P; Huhtala, T; Jääskeläinen, T; Juvonen, RO; Kaikkonen, S; Küblbeck, J; Laatikainen, R; Närvänen, A; Palvimo, JJ; Peräkylä, M; Petsalo, A; Poutiainen, PK; Pulkkinen, JT; Raunio, H | 1 |
| Clézardin, P; David, M; Descotes, F; Leblanc, R; Mege, F; Peyruchaud, O; Ribeiro, J; Sahay, D | 1 |
| Avanzo, RE; Carabelos, MN; D'Accorso, NB; Fascio, ML; Gueron, G; Schuster, F; Vazquez, E | 1 |
| Aleksic, T; Esashi, F; Gao, S; Lodhia, KA; Macaulay, VM | 1 |
| Liu, S; Parajuli, KR; You, Z; Zhang, Q | 2 |
| Aliev, G; Arunasree, KM; Bishayee, A; Dhananjaya, BL; Dharmapuri, G; Pedada, SR; Philip, GH; Putta, S; Rangaiah, G; Tambade, PJ; Yarla, NS | 1 |
| Bushman, LR; Chen, P; Hail, N | 1 |
| Gibbs, TC; Knoepp, SM; Meier, KE; Park, JJ; Rubio, MV; Snider, AJ; Um, T; Xie, Y; Zhang, Z | 1 |
| Butler, LM; Centenera, MM; Gillis, JL; Hanson, AR; Jindal, S; Knudsen, KE; Raj, GV; Risbridger, GP; Scher, HI; Sutherland, PD; Taylor, RA; Tilley, WD; Yeadon, T | 1 |
| Annadanam, A; Armour, E; Aziz, K; Cades, JA; Chettiar, ST; DeWeese, TL; Gajula, RP; Gandhi, N; Hales, RK; Herman, JM; Kato, Y; Schaeffer, EM; Song, D; Tran, PT; Wild, AT; Williams, RD; Zhang, Y | 1 |
| Bucala, R; Iczkowski, KA; Leng, L; Meyer-Siegler, KL; Vera, PL | 1 |
| Pickhardt, PA; Ripple, MO; Wilding, G | 1 |
| Berens, ME; Chen, H; Chu, L; Germain, L; Hersh, E; Hirth, KP; Jacobs, JS; Longhi, M; Mann, E; McMahon, G; Meredith, S; Powell, TJ; Schwartz, DP; Shawver, LK; Tang, C; Taylorson, L; Tsai, J; Ullrich, A | 1 |
| Balk, SP; Bubley, GJ; Chachoua, A; DePaoli, A; Hannah, A; Kabbinavar, F; Ko, YJ; Reese, D; Small, EJ; Taneja, S | 1 |
| George, D | 1 |
2 review(s) available for isoxazoles and Prostatic Neoplasms
| Article | Year |
|---|---|
Role of androgen receptor splice variants, their clinical relevance and treatment options.
Topics: Alternative Splicing; Androgen Antagonists; Androstadienes; Antineoplastic Agents, Hormonal; Benzamides; Benzhydryl Compounds; Benzimidazoles; Benzoquinones; Binding Sites; Chlorohydrins; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; HSP90 Heat-Shock Proteins; Humans; Isoindoles; Isoxazoles; Lactams, Macrocyclic; Male; Niclosamide; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Protein Domains; Protein Isoforms; Proteins; Receptors, Androgen; Resorcinols; RNA, Messenger | 2020 |
Platelet-derived growth factor receptors: a therapeutic target in solid tumors.
Topics: Antineoplastic Agents; Benzamides; Clinical Trials as Topic; Enzyme Inhibitors; Humans; Imatinib Mesylate; Isoxazoles; Leflunomide; Ligands; Male; Piperazines; Platelet-Derived Growth Factor; Prostatic Neoplasms; Protein-Tyrosine Kinases; Pyrimidines; Receptors, Platelet-Derived Growth Factor; Signal Transduction | 2001 |
1 trial(s) available for isoxazoles and Prostatic Neoplasms
| Article | Year |
|---|---|
A multi-institutional phase ii study of SU101, a platelet-derived growth factor receptor inhibitor, for patients with hormone-refractory prostate cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Humans; Immunohistochemistry; Isoxazoles; Leflunomide; Male; Middle Aged; Pain Measurement; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Platelet-Derived Growth Factor; Time Factors; Treatment Outcome | 2001 |
18 other study(ies) available for isoxazoles and Prostatic Neoplasms
| Article | Year |
|---|---|
Rational design, synthesis and biological evaluation of benzo[d]isoxazole derivatives as potent BET bivalent inhibitors for potential treatment of prostate cancer.
Topics: Cell Proliferation; Humans; Isoxazoles; Male; Prostatic Neoplasms; Protein Domains; Transcription Factors | 2023 |
Y06014 is a selective BET inhibitor for the treatment of prostate cancer.
Topics: Antineoplastic Agents; Cell Cycle Proteins; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Indoles; Isoxazoles; Male; Molecular Docking Simulation; Molecular Structure; Prostatic Neoplasms; Protein Binding; Protein Domains; Small Molecule Libraries; Structure-Activity Relationship; Transcription Factors | 2021 |
Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion.
Topics: Aged; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cytoskeleton; Endosomes; Fibronectins; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Male; Middle Aged; Neoplasm Invasiveness; Prostatic Neoplasms; Resorcinols; Secretory Pathway | 2018 |
Hsp-27 and NF-κB pathway is associated with AR/AR-V7 expression in prostate cancer cells.
Topics: Anisoles; Apoptosis; Cell Line, Tumor; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; I-kappa B Kinase; Isoxazoles; Male; Molecular Chaperones; NF-kappa B; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Signal Transduction; Sulfones | 2019 |
Preclinical pharmacology of FL442, a novel nonsteroidal androgen receptor modulator.
Topics: Aged; Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Anilides; Animals; Antineoplastic Agents; Benzamides; Cell Line, Tumor; Cell Proliferation; Chlorocebus aethiops; COS Cells; Drug Evaluation, Preclinical; Female; Humans; Isoxazoles; Male; Mice; Mice, Inbred DBA; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms; Receptors, Androgen; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Progesterone; Tosyl Compounds; Xenograft Model Antitumor Assays | 2014 |
Identification of heparin-binding EGF-like growth factor (HB-EGF) as a biomarker for lysophosphatidic acid receptor type 1 (LPA1) activation in human breast and prostate cancers.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Heparin-binding EGF-like Growth Factor; Humans; Isoxazoles; Lysophospholipids; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Propionates; Prostatic Neoplasms; Receptors, Lysophosphatidic Acid; RNA, Messenger; Signal Transduction; Xenograft Model Antitumor Assays | 2014 |
Differential effect of heterocyclic D-ribofuranoside derivatives on human prostate cancer cell viability and cell cycle progression.
Topics: Alkenes; Antineoplastic Agents; Carbohydrates; Cell Line, Tumor; Cell Survival; G1 Phase Cell Cycle Checkpoints; Humans; Isoxazoles; Male; Prostatic Neoplasms; Resting Phase, Cell Cycle; Triazoles | 2014 |
Suppression of homologous recombination sensitizes human tumor cells to IGF-1R inhibition.
Topics: Blotting, Western; Boron Compounds; BRCA1 Protein; BRCA2 Protein; CDC2 Protein Kinase; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; DNA Breaks, Double-Stranded; DNA Repair; Histones; Homologous Recombination; Humans; Isoxazoles; Male; Microscopy, Fluorescence; Phosphorylation; Prostatic Neoplasms; PTEN Phosphohydrolase; Pyrimidines; Quinolines; Rad51 Recombinase; Receptor, IGF Type 1; RNA Interference; Thiazoles | 2015 |
Aminomethylphosphonic acid and methoxyacetic acid induce apoptosis in prostate cancer cells.
Topics: Acetates; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Line, Tumor; G1 Phase; Gene Expression Regulation, Neoplastic; Humans; Isoxazoles; Male; Organophosphonates; Prostate; Prostatic Neoplasms; Tetrazoles | 2015 |
Aminomethylphosphonic acid inhibits growth and metastasis of human prostate cancer in an orthotopic xenograft mouse model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cyclin D1; Disease Models, Animal; Enzyme Activation; Humans; Inhibitor of Apoptosis Proteins; Isoxazoles; Male; Mice; Mice, Nude; Neoplasm Metastasis; Neovascularization, Pathologic; Organophosphonates; Prostatic Neoplasms; Tetrazoles; Ubiquitin-Protein Ligases; Xenograft Model Antitumor Assays | 2016 |
Synthesis of new secretory phospholipase A2-inhibitory indole containing isoxazole derivatives as anti-inflammatory and anticancer agents.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Indoles; Isoxazoles; Male; Mice; Models, Molecular; Phospholipases A2, Secretory; Prostatic Neoplasms; Rats, Wistar | 2016 |
Teriflunomide (leflunomide) promotes cytostatic, antioxidant, and apoptotic effects in transformed prostate epithelial cells: evidence supporting a role for teriflunomide in prostate cancer chemoprevention.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Caspases; Cell Line, Transformed; Cytochromes c; Dose-Response Relationship, Drug; Epithelial Cells; Flow Cytometry; Humans; Immunoblotting; Isoxazoles; Leflunomide; Male; Membrane Potential, Mitochondrial; Mitochondria; Oxygen Consumption; Prostate; Prostatic Neoplasms; Reactive Oxygen Species; Time Factors; Tumor Cells, Cultured | 2010 |
Effects of lysophosphatidic acid on calpain-mediated proteolysis of focal adhesion kinase in human prostate cancer cells.
Topics: Adenocarcinoma; Animals; Calpain; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Screening Assays, Antitumor; Fibroblasts; Focal Adhesion Protein-Tyrosine Kinases; Humans; Ionomycin; Isoxazoles; Lysophospholipids; Male; Paxillin; Phosphorylation; Propionates; Prostatic Neoplasms; Proteolysis; Rats; Thapsigargin | 2012 |
Evidence for efficacy of new Hsp90 inhibitors revealed by ex vivo culture of human prostate tumors.
Topics: Aged; Antineoplastic Agents; Apoptosis; Benzoquinones; Cell Proliferation; Cell Survival; Drug Evaluation, Preclinical; G2 Phase Cell Cycle Checkpoints; Gene Expression; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Lactams, Macrocyclic; Male; Middle Aged; Molecular Targeted Therapy; Prostatic Neoplasms; Pyridones; Pyrimidines; Resorcinols; Tissue Culture Techniques; Tumor Cells, Cultured | 2012 |
Novel Hsp90 inhibitor NVP-AUY922 radiosensitizes prostate cancer cells.
Topics: Animals; Apoptosis; Cell Cycle Checkpoints; Cell Division; Cell Growth Processes; Cell Line, Tumor; Combined Modality Therapy; Disease Models, Animal; Down-Regulation; G2 Phase; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Male; Mice; Mice, Transgenic; Prostatic Neoplasms; Radiation-Sensitizing Agents; Random Allocation; Resorcinols; Signal Transduction; Xenograft Model Antitumor Assays | 2013 |
Inhibition of macrophage migration inhibitory factor or its receptor (CD74) attenuates growth and invasion of DU-145 prostate cancer cells.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Cell Line, Tumor; Cell Proliferation; Histocompatibility Antigens Class II; Humans; Intramolecular Oxidoreductases; Isoxazoles; Macrophage Migration-Inhibitory Factors; Male; Mice; Neoplasm Invasiveness; Neoplasm Proteins; Prostatic Neoplasms; Signal Transduction; Transplantation, Heterologous | 2006 |
Alteration in gamma-glutamyl transpeptidase activity and messenger RNA of human prostate carcinoma cells by androgen.
Topics: Androgens; Borates; Cell Division; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutathione; Glycylglycine; Humans; Immunohistochemistry; Isoxazoles; Male; Prostatic Neoplasms; RNA, Messenger; Serine; Tumor Cells, Cultured | 1997 |
Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide.
Topics: 3T3 Cells; Animals; Brain Neoplasms; Cell Survival; Epidermal Growth Factor; Female; Glioma; Growth Inhibitors; Humans; Isoxazoles; Leflunomide; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Ovarian Neoplasms; Platelet-Derived Growth Factor; Prostatic Neoplasms; Rats; Receptor, Platelet-Derived Growth Factor beta; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Signal Transduction; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured | 1997 |