Page last updated: 2024-08-21

isoxazoles and Polyarthritis

isoxazoles has been researched along with Polyarthritis in 29 studies

Research

Studies (29)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (17.24)	18.7374
1990's	2 (6.90)	18.2507
2000's	16 (55.17)	29.6817
2010's	5 (17.24)	24.3611
2020's	1 (3.45)	2.80

Authors

Authors	Studies
Lucena, F; McDougall, JJ	1
Cortés-Hernández, J; Egri, N; Ordi-Ros, J; Vilardell-Tarrés, M	1
Jia, Y; Miao, H; Wang, L; Yang, Y; Zhang, XY; Zhou, YS	1
Collins, D; Duke, O; Kaul, A; Kiely, PD; O'Reilly, DT; Slack, RK; Walmsley, J	1
Cao, GQ; Chakrabarti, PP; Henkle, B; Hsieh, F; Lee, MR; Middleton, S; Pettus, LH; Plant, MH; Powers, DA; Rzasa, RM; Saris, CJ; Sham, K; Sherman, L; Syed, R; Tasker, AS; Tudor, Y; Wong, LM; Wurz, RP; Xu, S; Yu, V; Zhang, D	1
Baker, TA; Colopy, SA; Muir, P	1
Haroon, M; O'Gradaigh, D	1
Artifoni, M; Puéchal, X	1
Ormrod, D; Wagstaff, AJ; Wellington, K	1
Bandyopadhyay, D	1
Magari, K; Miyata, S; Mutoh, S; Nishigaki, F; Ohkubo, Y	1
Braun, J; Haibel, H; Rudwaleit, M; Sieper, J	1
Topol, EJ	1
Okie, S	1
Lange, U; Müller-Ladner, U; Piegsa, M; Strunk, J	1
Caruso, A; Ferri, C; Giuggioli, D; Sebastiani, M; Vesprini, E	1
Tabrizchi, R	1
Evans, SJ; Lawson, TM; Siebert, S; Webb, D	1
Li, SG	1
Beuers, U; Budenhofer, U; Kremer, AE; Rust, C	1
Brauer, R; Henzgen, S; Katenkamp, D; Petrow, PK; Thoss, K	1
FitzGerald, GA	1
Gotta, AW	1
DiPasquale, G; Gingold, J; Rassaert, C; Schwartz, E; Welaj, P	1
Diamantis, W; Ludwig, BJ; Sofia, RD	1
Hambleton, P; McMahon, S	1
Hirschelmann, R; Schade, R	1
Buyniski, JP; Gylys, JA; Pasternak, RD; Siminoff, P; Wadopian, NS; Wright, RN	1
Bartlett, RR; Schleyerbach, R	1

Reviews

3 review(s) available for isoxazoles and Polyarthritis

Article	Year
How to treat refractory arthritis in lupus? Joint bone spine, 2012, Volume: 79, Issue:4 Topics: Abatacept; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antimalarials; Antirheumatic Agents; Arthritis; Azathioprine; Drug Resistance; Drug Therapy, Combination; Glucocorticoids; Humans; Immunoconjugates; Immunosuppressive Agents; Isoxazoles; Leflunomide; Lupus Erythematosus, Systemic; Methotrexate; Mycophenolic Acid; Rituximab	2012
Valdecoxib. Drugs, 2002, Volume: 62, Issue:14 Topics: Arthritis; Clinical Trials as Topic; Dysmenorrhea; Female; Humans; Isoxazoles; Pain; Sulfonamides	2002
Valdecoxib (Pharmacia). Current opinion in investigational drugs (London, England : 2000), 2002, Volume: 3, Issue:2 Topics: Arthritis; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drugs, Investigational; Humans; Isoenzymes; Isoxazoles; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship; Sulfonamides; Treatment Outcome	2002

Trials

2 trial(s) available for isoxazoles and Polyarthritis

Article	Year
Efficacy and safety of combining intra-articular methylprednisolone and anti-TNF agent to achieve prolonged remission in patients with recurrent inflammatory monoarthritis. Joint bone spine, 2010, Volume: 77, Issue:3 Topics: Adalimumab; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis; Drug Therapy, Combination; Etanercept; Female; Follow-Up Studies; Humans; Immunoglobulin G; Injections, Intra-Articular; Isoxazoles; Knee Joint; Leflunomide; Male; Methylprednisolone; Middle Aged; Receptors, Tumor Necrosis Factor; Remission Induction; Secondary Prevention; Tumor Necrosis Factor-alpha	2010
Six months open label trial of leflunomide in active ankylosing spondylitis. Annals of the rheumatic diseases, 2005, Volume: 64, Issue:1 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis; Arthritis, Psoriatic; Female; Humans; Isoxazoles; Leflunomide; Male; Middle Aged; Patient Dropouts; Severity of Illness Index; Spondylitis, Ankylosing; Treatment Outcome	2005

Article

Year

Efficacy and safety of combining intra-articular methylprednisolone and anti-TNF agent to achieve prolonged remission in patients with recurrent inflammatory monoarthritis.

Joint bone spine, 2010, Volume: 77, Issue:3

Topics: Adalimumab; Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis; Drug Therapy, Combination; Etanercept; Female; Follow-Up Studies; Humans; Immunoglobulin G; Injections, Intra-Articular; Isoxazoles; Knee Joint; Leflunomide; Male; Methylprednisolone; Middle Aged; Receptors, Tumor Necrosis Factor; Remission Induction; Secondary Prevention; Tumor Necrosis Factor-alpha

2010

Six months open label trial of leflunomide in active ankylosing spondylitis.

Annals of the rheumatic diseases, 2005, Volume: 64, Issue:1

Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis; Arthritis, Psoriatic; Female; Humans; Isoxazoles; Leflunomide; Male; Middle Aged; Patient Dropouts; Severity of Illness Index; Spondylitis, Ankylosing; Treatment Outcome

2005

Other Studies

24 other study(ies) available for isoxazoles and Polyarthritis

Article	Year
Pain responses to protease-activated receptor-2 stimulation in the spinal cord of naïve and arthritic rats. Neuroscience letters, 2020, 11-20, Volume: 739 Topics: Animals; Arthritis; Dipeptides; Disease Models, Animal; Hyperalgesia; Isoxazoles; Male; Nociception; Pain Threshold; Rats, Wistar; Receptor, PAR-2; Spinal Cord	2020
Etanercept in refractory lupus arthritis: An observational study. Seminars in arthritis and rheumatism, 2015, Volume: 44, Issue:6 Topics: Adult; Antirheumatic Agents; Arthritis; Autoantibodies; Cohort Studies; Etanercept; Female; Glucocorticoids; Humans; Hydroxychloroquine; Immunosuppressive Agents; Isoxazoles; Leflunomide; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Treatment Outcome	2015
[Clinical characteristics of 4 cases of scleritis associated with systemic lupus erythematosus]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2016, 12-18, Volume: 48, Issue:6 Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antinuclear; Arthritis; Cyclophosphamide; Disease Progression; Female; Hematologic Diseases; Humans; Isoxazoles; Leflunomide; Lung Diseases, Interstitial; Lupus Erythematosus, Systemic; Lupus Nephritis; Male; Middle Aged; Pain; Prognosis; Raynaud Disease; Recurrence; Scleritis; Serositis; Treatment Outcome; Triamcinolone Acetonide; Uveitis; Vision Disorders	2016
Tolerability of methotrexate and leflunomide combination therapy for inflammatory arthritis in routine clinical practice: results of a four-centre study. Rheumatology (Oxford, England), 2008, Volume: 47, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis; Drug Therapy, Combination; Female; Humans; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged	2008
3-amino-7-phthalazinylbenzoisoxazoles as a novel class of potent, selective, and orally available inhibitors of p38alpha mitogen-activated protein kinase. Journal of medicinal chemistry, 2008, Oct-23, Volume: 51, Issue:20 Topics: Administration, Oral; Amines; Animals; Arthritis; Benzene; Crystallography, X-Ray; Disease Models, Animal; Humans; Isoxazoles; Mitogen-Activated Protein Kinase 14; Models, Molecular; Molecular Structure; Phthalazines; Protein Kinase Inhibitors; Rats; Structure-Activity Relationship	2008
Efficacy of leflunomide for treatment of immune-mediated polyarthritis in dogs: 14 cases (2006-2008). Journal of the American Veterinary Medical Association, 2010, Feb-01, Volume: 236, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Autoimmune Diseases; Dog Diseases; Dogs; Female; Isoxazoles; Leflunomide; Male; Retrospective Studies	2010
Exfoliative dermatitis induced by leflunomide therapy. The Journal of dermatology, 2003, Volume: 30, Issue:11 Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Dermatitis, Exfoliative; Diagnosis, Differential; Humans; Isoxazoles; Leflunomide; Male; Middle Aged	2003
Comparison of anti-arthritic properties of leflunomide with methotrexate and FK506: effect on T cell activation-induced inflammatory cytokine production in vitro and rat adjuvant-induced arthritis. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53, Issue:10 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Bone Marrow Cells; CD28 Antigens; CD3 Complex; Cell Proliferation; Cytokines; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunosuppressive Agents; Inflammation; Isoxazoles; Leflunomide; Leukocytes; Leukocytes, Mononuclear; Lymphocyte Activation; Methotrexate; Mice; Neutrophils; Random Allocation; Rats; Rats, Inbred Lew; T-Lymphocytes; Tacrolimus; Time Factors	2004
Arthritis medicines and cardiovascular events--"house of coxibs". JAMA, 2005, Jan-19, Volume: 293, Issue:3 Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Diseases; Celecoxib; Cyclooxygenase Inhibitors; Drug Approval; Humans; Isoxazoles; Pyrazoles; Sulfonamides; United States; United States Food and Drug Administration	2005
Raising the safety bar--the FDA's coxib meeting. The New England journal of medicine, 2005, Mar-31, Volume: 352, Issue:13 Topics: Advertising; Advisory Committees; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular Diseases; Celecoxib; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Drug Approval; Drug Industry; Drug Labeling; Humans; Isoxazoles; Lactones; Product Surveillance, Postmarketing; Pyrazoles; Sulfonamides; Sulfones; United States; United States Food and Drug Administration	2005
Anti-Jo-1 antibody positive polymyositis--successful therapy with leflunomide. Autoimmunity, 2006, Volume: 39, Issue:3 Topics: Antibodies, Antinuclear; Arthritis; Autoantibodies; Azathioprine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Isoxazoles; Leflunomide; Middle Aged; Polymyositis; Prednisolone	2006
Successful treatment with leflunomide of arthritis in systemic sclerosis patients. Rheumatology (Oxford, England), 2006, Volume: 45, Issue:9 Topics: Adult; Antirheumatic Agents; Arthritis; Female; Humans; Isoxazoles; Leflunomide; Middle Aged; Scleroderma, Systemic	2006
Coxibs: can this class of drugs survive? Vascular health and risk management, 2005, Volume: 1, Issue:1 Topics: Arthritis; Cardiovascular Diseases; Celecoxib; Cyclooxygenase 2 Inhibitors; Etoricoxib; Evidence-Based Medicine; Half-Life; Humans; Isoxazoles; Lactones; Patient Selection; Pyrazoles; Pyridines; Sulfonamides; Sulfones	2005
Renal tubular acidosis associated with leflunomide. Rheumatology (Oxford, England), 2007, Volume: 46, Issue:6 Topics: Acidosis, Renal Tubular; Adult; Antirheumatic Agents; Arthritis; Female; Humans; Isoxazoles; Leflunomide	2007
Clinical images: healing of sacroiliitis with leflunomide and sulfasalazine treatment. Arthritis and rheumatism, 2008, Volume: 58, Issue:5 Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Humans; Isoxazoles; Leflunomide; Male; Sacroiliac Joint; Sulfasalazine; Tomography, X-Ray Computed	2008
[A 47-year-old dog breeder with chronic polyarthritis, weight loss and high fever]. Zeitschrift fur Gastroenterologie, 2008, Volume: 46, Issue:5 Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis; Arthritis, Rheumatoid; Diagnosis, Differential; Disease Progression; Fever of Unknown Origin; Humans; Immunologic Deficiency Syndromes; Isoxazoles; Leflunomide; Male; Middle Aged; Polymerase Chain Reaction; Risk Factors; Systemic Inflammatory Response Syndrome; Tropheryma; Weight Loss; Whipple Disease	2008
Immunomodulation of rat antigen-induced arthritis by leflunomide alone and in combination with cyclosporin A. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45, Issue:2 Topics: Animals; Arthritis; Autoantibodies; Cyclosporine; Female; Immunosuppressive Agents; Isoxazoles; Leflunomide; Organ Size; Rats; Rats, Wistar; Serum Albumin, Bovine	1996
Nonsteroidal anti-inflammatory drugs, coxibs, and cardio-renal physiology: a mechanism-based approach. The American journal of cardiology, 2002, Mar-21, Volume: 89, Issue:6A Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cardiovascular System; Celecoxib; Cyclooxygenase Inhibitors; Dysmenorrhea; Female; Humans; Isoxazoles; Lactones; Male; Pyrazoles; Sulfonamides; Sulfones	2002
Effects of multiple treatments of isoxicam on organ weights and serum SGPT, AP, and BUN in adjuvant-induced polyarthritic rats. Research communications in chemical pathology and pharmacology, 1978, Volume: 19, Issue:3 Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Arthritis; Arthritis, Experimental; Blood Urea Nitrogen; Isoxazoles; Male; Organ Size; Oxazoles; Piroxicam; Rats; Thiazines	1978
Comparative anti-inflammatory, analgesic, and antipyretic activities of 7-chloro-3,3a-dihydro-2-methyl-2H,9H-isoxazolo-(3,2-b)(1,3)-benzoxazin-9-one and 5-chlorosalicylic acid in rats. Journal of pharmaceutical sciences, 1975, Volume: 64, Issue:8 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Body Temperature; Edema; Isoxazoles; Male; Oxazines; Oxazoles; Rats; Salicylates; Stomach Ulcer	1975
Drug actions on delayed-type hypersensitivity in rats with developing and established adjuvant arthritis. Agents and actions, 1990, Volume: 29, Issue:3-4 Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Bacterial; Arthritis; Arthritis, Experimental; Cyclosporins; Freund's Adjuvant; Hypersensitivity, Delayed; Indomethacin; Isoxazoles; Kinetics; Leflunomide; Male; Mycobacterium; Propionates; Rats; Steroids	1990
6-Sulfanilamidoindazole arthritis in rats: influence of the new anti-inflammatory agent CGP 28237 and of the immunomodulating compound HWA 486 on degree of arthritis and on acute phase reaction. Die Pharmazie, 1988, Volume: 43, Issue:1 Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Indans; Indenes; Inflammation; Isoxazoles; Leflunomide; Oxazoles; Rats; Sulfanilamides	1988
Disease modifying activity of HWA 486 in rat adjuvant-induced arthritis. Agents and actions, 1987, Volume: 21, Issue:3-4 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Cyclosporins; Hypersensitivity, Delayed; In Vitro Techniques; Isoxazoles; Leflunomide; Lymphocyte Activation; Male; Oxazoles; Rats; Rats, Inbred Lew	1987
Immunopharmacological profile of a novel isoxazol derivative, HWA 486, with potential antirheumatic activity--I. Disease modifying action on adjuvant arthritis of the rat. International journal of immunopharmacology, 1985, Volume: 7, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Cyclophosphamide; Immunosuppressive Agents; Isoxazoles; Leflunomide; Lymphocyte Activation; Male; Oxazoles; Radiography; Rats; Rats, Inbred Lew	1985