isoxazoles has been researched along with Neoplasm Metastasis in 24 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (25.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (16.67) | 29.6817 |
2010's | 12 (50.00) | 24.3611 |
2020's | 2 (8.33) | 2.80 |
Authors | Studies |
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Ahirwar, DK; Charan, M; Chatterjee, N; Das, S; Ganju, RK; Kaul, K; Mishra, S; Misri, S; Satoskar, AR; Varikuti, S | 1 |
Abel, L; Baschnagel, AM; Clark, PA; Elnaggar, JH; Kaushik, S; Kimple, RJ; Kromke, AC; Leal, TA; Longhurst, CA; Nickel, KP; Skiba, JH; VanBeek, HJ; Zhao, SG | 1 |
Feng, Z; Zheng, J; Zhu, J | 1 |
Ballinari, D; Brasca, MG; Casale, E; Ciomei, M; De Ponti, A; Degrassi, A; Donati, D; Felder, E; Fogliatto, G; Galvani, A; Germani, M; Gianellini, L; Guanci, M; Isacchi, A; Mantegani, S; Paolucci, M; Pesenti, E; Polucci, P; Russo, M; Sola, F; Valsasina, B; Visco, C; Zuccotto, F | 1 |
Abdel-Latif, A; Morris, AJ; Ratajczak, MZ; Schneider, G; Sellers, ZP | 1 |
Bhagat, S; Fullerton, SL; Kenner, DJ | 1 |
Liu, S; Parajuli, KR; You, Z; Zhang, Q | 1 |
Furukawa, S; Handa, H; Hashimoto, A; Hashimoto, S; Mikami, S; Oikawa, T; Okada, Y; Onodera, Y; Oya, M; Sabe, H; Sugino, H; Yoshikawa, A | 1 |
Benítez, S; Cabiscol, E; Dolcet, X; Domingo, M; Maiques, O; Marti, RM; Martinez, M; Matias-Guiu, X; Ribera, J; Santacana, M; Valls, J; Vea, A; Vilella, R; Yeramian, A | 1 |
Aglietta, M; Ahmed, S; Akimov, M; Alba, E; Armstrong, AC; Beck, JT; Biganzoli, L; Campone, M; Hsu Schmitz, SF; Kong, A; Lee, SC; Lefebvre, C; López López, R; Rea, D | 1 |
Hedley, D; Krzyzanowska, MK; Moore, MJ; Renouf, DJ; Schmuck, M; Wang, L | 1 |
Im, DS; Ishii, S; Kimura, T; Komachi, M; Mogi, C; Ohta, H; Okajima, F; Sato, K; Takeyoshi, I; Tobo, M; Tomura, H; Yamada, T; Yanagida, K | 1 |
Abel, U; Deuschle, U; Kinzel, O; Kremoser, C; Schlüter, T; Schüler, J; Schulz, A | 1 |
Chen, G; Gong, ZC; Jia, J; Lin, ZQ; Liu, H; Sun, ZJ; Wang, FQ; Zhang, W; Zhao, YF; Zhu, JY | 1 |
Ikeya, T; Im, DS; Kimura, T; Komachi, M; Kuwabara, A; Malchinkhuu, E; Morishita, Y; Ogawa, T; Ohta, H; Ohwada, S; Okajima, F; Sato, K; Tamoto, K; Tanahashi, Y; Tobo, M; Tomura, H; Yamada, T; Yanagita, Y | 1 |
Bloemendaal, AL; Borel Rinkes, IH; Kranenburg, O; Smakman, N; van Diest, P; Vogten, JM | 1 |
Bordet, JC; Boucharaba, A; Clézardin, P; Guglielmi, J; Peyruchaud, O; Serre, CM | 1 |
Aherne, W; Barril, X; Box, G; Boxall, F; Boxall, K; Brough, PA; Cansfield, JE; Cheung, KM; de Haven Brandon, A; Drysdale, MJ; Dymock, B; Eccles, SA; Finch, H; Gowan, S; Hayes, A; Howes, R; Hubbard, RE; James, K; Jones, K; Kalusa, A; Martins, V; Massey, A; Matthews, TP; McDonald, E; Patterson, L; Pearl, L; Prodromou, C; Raynaud, FI; Rowlands, M; Sharp, SY; Surgenor, A; Urban, F; Valenti, M; Webb, P; Wood, M; Workman, P; Wright, L | 1 |
Bodey, G; Fleishman, G; Murphy, WK; Yap, HY | 1 |
Ansbacher, R | 1 |
Carbone, PP; Davis, TE; Earle, JD; Elson, PJ; Glover, DJ; Hahn, RG; Kvols, LK; Trump, DL; Vogl, SE | 1 |
Chang, YC; Falkson, G; Knuiman, MW; Pandya, KJ; Skeel, RT; Willson, JK; Wolter, JM | 1 |
Booth, BW; Budman, D; Ellison, RR; Khojasteh, A; Korzun, AH; Weiss, RB; Wood, W | 1 |
Adolphson, CC; Ajani, JA; Barlogie, B; Bedikian, AY; Bodey, GP; Korinek, J; Stroehlein, JR | 1 |
5 trial(s) available for isoxazoles and Neoplasm Metastasis
Article | Year |
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Effect of preintravenous injection of parecoxib, combined with transversus abdominis plane block in strategy of enhanced recovery after radical resection of colorectal cancer.
Topics: Adolescent; Adult; Aged; Colorectal Neoplasms; Combined Modality Therapy; Cyclooxygenase 2 Inhibitors; Female; Humans; Isoxazoles; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pain Measurement; Pain, Postoperative; Tomography, X-Ray Computed; Treatment Outcome; Young Adult | 2018 |
Phase 1B/2 study of the HSP90 inhibitor AUY922 plus trastuzumab in metastatic HER2-positive breast cancer patients who have progressed on trastuzumab-based regimen.
Topics: Adult; Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Breast Neoplasms; Cohort Studies; Disease Progression; Dose-Response Relationship, Drug; Female; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Kaplan-Meier Estimate; Middle Aged; Neoplasm Metastasis; Receptor, ErbB-2; Resorcinols; Trastuzumab; Treatment Outcome | 2016 |
A phase II study of the HSP90 inhibitor AUY922 in chemotherapy refractory advanced pancreatic cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Carcinoma, Pancreatic Ductal; Disease-Free Survival; Female; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Male; Middle Aged; Neoplasm Metastasis; Resorcinols; Survival Rate; Treatment Outcome | 2016 |
Phase II clinical trial of acivicin in advanced breast cancer: an Eastern Cooperative Oncology Group Study.
Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Central Nervous System Diseases; Clinical Trials as Topic; Drug Evaluation; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Isoxazoles; Middle Aged; Neoplasm Metastasis; Oxazoles | 1986 |
Phase II trial of acivicin in advanced breast carcinoma: a Cancer and Leukemia Group B Study.
Topics: Adenocarcinoma; Aged; Antibiotics, Antineoplastic; Brain Diseases; Breast Neoplasms; Clinical Trials as Topic; Drug Evaluation; Female; Hematologic Diseases; Humans; Isoxazoles; Middle Aged; Neoplasm Metastasis; Oxazoles | 1986 |
19 other study(ies) available for isoxazoles and Neoplasm Metastasis
Article | Year |
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Macrophage migration inhibitory factor inhibition as a novel therapeutic approach against triple-negative breast cancer.
Topics: Animals; Apoptosis; Caspases; Cell Movement; Cell Survival; Cytochromes c; Disease Progression; Enzyme Activation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Inflammation; Intramolecular Oxidoreductases; Isoxazoles; Macrophage Migration-Inhibitory Factors; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Morpholines; Neoplasm Metastasis; Neoplasm Transplantation; Treatment Outcome; Triple Negative Breast Neoplasms; Wound Healing | 2020 |
ATR Inhibitor M6620 (VX-970) Enhances the Effect of Radiation in Non-Small Cell Lung Cancer Brain Metastasis Patient-Derived Xenografts.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Female; Heterografts; Humans; Isoxazoles; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Pyrazines; Treatment Outcome | 2021 |
NMS-E973, a novel synthetic inhibitor of Hsp90 with activity against multiple models of drug resistance to targeted agents, including intracranial metastases.
Topics: Animals; Antineoplastic Agents; Binding Sites; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; HSP90 Heat-Shock Proteins; Humans; Inhibitory Concentration 50; Isoxazoles; Mice; Molecular Conformation; Molecular Docking Simulation; Neoplasm Metastasis; Organ Specificity; Protein Binding; Proteolysis; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Bioactive lipids, LPC and LPA, are novel prometastatic factors and their tissue levels increase in response to radio/chemotherapy.
Topics: Animals; Bone Marrow; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Chemotactic Factors; Drug Resistance, Neoplasm; Gamma Rays; Humans; Isoxazoles; Lysophosphatidylcholines; Lysophospholipids; MAP Kinase Signaling System; Mice, Inbred C57BL; Mice, SCID; Neoplasm Metastasis; Propionates; Receptors, G-Protein-Coupled; Rhabdomyosarcoma; Tumor Microenvironment; Vincristine | 2014 |
Daily subcutaneous parecoxib injection for cancer pain: an open label pilot study.
Topics: Analgesics, Opioid; Analysis of Variance; Bone Neoplasms; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Female; Hospital Units; Humans; Injections, Subcutaneous; Isoxazoles; Male; Neoplasm Metastasis; Pain Management; Pain Measurement; Palliative Care; Pilot Projects; Treatment Outcome; Victoria | 2015 |
Aminomethylphosphonic acid inhibits growth and metastasis of human prostate cancer in an orthotopic xenograft mouse model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cyclin D1; Disease Models, Animal; Enzyme Activation; Humans; Inhibitor of Apoptosis Proteins; Isoxazoles; Male; Mice; Mice, Nude; Neoplasm Metastasis; Neovascularization, Pathologic; Organophosphonates; Prostatic Neoplasms; Tetrazoles; Ubiquitin-Protein Ligases; Xenograft Model Antitumor Assays | 2016 |
Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer.
Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Adult; Aged; Aged, 80 and over; Amides; Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Female; GTP-Binding Protein alpha Subunits, G12-G13; Guanine Nucleotide Exchange Factors; HEK293 Cells; Humans; Immunohistochemistry; Indoles; Isoxazoles; Kidney Neoplasms; Lysophospholipids; Male; Mice, Nude; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Nerve Tissue Proteins; Propionates; Pyridines; Pyrroles; Receptors, Lysophosphatidic Acid; Signal Transduction; Sirolimus; Sunitinib; Triazoles | 2016 |
2-phenylethynesulphonamide (PFT-μ) enhances the anticancer effect of the novel hsp90 inhibitor NVP-AUY922 in melanoma, by reducing GSH levels.
Topics: Animals; Antineoplastic Agents; Autophagy; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Glutathione; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Isoxazoles; MAP Kinase Signaling System; Melanoma; Mice, SCID; Neoplasm Metastasis; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Resorcinols; RNA, Messenger; Skin; Sulfonamides; Xenograft Model Antitumor Assays | 2016 |
Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo.
Topics: Animals; Ascites; Cell Line, Tumor; Cell Movement; Humans; Isoxazoles; Lysophospholipids; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Pancreatic Neoplasms; Peritoneal Neoplasms; Propionates; Receptors, Lysophosphatidic Acid; Xenograft Model Antitumor Assays | 2012 |
FXR controls the tumor suppressor NDRG2 and FXR agonists reduce liver tumor growth and metastasis in an orthotopic mouse xenograft model.
Topics: Animals; Binding Sites; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Hep G2 Cells; Humans; Isoxazoles; Liver; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Neoplasm Metastasis; Protein Binding; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tumor Burden; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2012 |
Overexpression of macrophage migration inhibitory factor in adenoid cystic carcinoma: correlation with enhanced metastatic potential.
Topics: Carcinoma, Adenoid Cystic; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Gene Expression; Humans; Isoxazoles; Macrophage Migration-Inhibitory Factors; MAP Kinase Kinase 4; Neoplasm Metastasis; Salivary Gland Neoplasms | 2013 |
Lysophosphatidic acid (LPA) in malignant ascites stimulates motility of human pancreatic cancer cells through LPA1.
Topics: Adult; Animals; Ascites; Blotting, Northern; Cell Adhesion; Cell Division; Cell Line, Tumor; Cell Movement; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Epidermal Growth Factor; Female; Humans; Isoxazoles; Lipids; Lysophospholipids; Male; Mice; Mice, Inbred BALB C; Middle Aged; Monoacylglycerol Lipases; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Pancreatic Neoplasms; Pertussis Toxin; Propionates; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transfection | 2004 |
Cyclooxygenase-2 is a target of KRASD12, which facilitates the outgrowth of murine C26 colorectal liver metastases.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Genes, ras; Image Processing, Computer-Assisted; Immunohistochemistry; Isoxazoles; Ki-67 Antigen; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Microcirculation; Mutation; Neoplasm Metastasis; Neoplasm Transplantation; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins p21(ras); RNA Interference; Time Factors | 2005 |
The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases.
Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cytokines; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Isoxazoles; Lysophospholipids; Mice; Neoplasm Metastasis; Osteoclasts; Propionates; Receptors, Lysophosphatidic Acid | 2006 |
NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis.
Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Cycle; Cell Division; Female; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Mice; Mice, Nude; Neoplasm Metastasis; Neovascularization, Pathologic; Resorcinols; Transplantation, Heterologous | 2008 |
Phase II trial of acivicin in advanced metastatic breast cancer.
Topics: Adult; Breast Neoplasms; Drug Evaluation; Female; Humans; Isoxazoles; Middle Aged; Neoplasm Metastasis; Oxazoles | 1983 |
Treatment of endometriosis with Danazol.
Topics: Adult; Castration; Endometriosis; Ethisterone; Fallopian Tubes; Female; Humans; Hysterectomy; Isoxazoles; Neoplasm Metastasis; Neoplasm Recurrence, Local; Ovarian Neoplasms; Oxazoles; Uterine Neoplasms | 1975 |
Phase II trials of 5-day vinblastine infusion (NSC 49842), L-alanosine (NSC 153353), acivicin (NSC 163501), and aminothiadiazole (NSC 4728) in patients with recurrent or metastatic renal cell carcinoma.
Topics: Adult; Aged; Alanine; Antineoplastic Agents; Carcinoma, Renal Cell; Drug Administration Schedule; Drug Evaluation; Female; Humans; Isoxazoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Oxazoles; Thiadiazoles; Vinblastine | 1988 |
Phase II trial of acivicin in patients with advanced colorectal carcinoma.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Colonic Neoplasms; Drug Evaluation; Female; Humans; Isoxazoles; Leukopenia; Male; Middle Aged; Nausea; Neoplasm Metastasis; Oxazoles; Rectal Neoplasms; Vomiting | 1986 |