Page last updated: 2024-08-21

isoxazoles and Myeloproliferative Disorders

isoxazoles has been researched along with Myeloproliferative Disorders in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Abhyankar, S; Balusu, R; Bhalla, KN; Fiskus, W; Ha, K; Hembruff, SL; Manshouri, T; McGuirk, J; Rao, NN; Rao, R; Smith, JE; Venkannagari, S; Verstovsek, S	1
Baffert, F; Bird, L; Bradner, JE; Chapuy, B; Christie, AL; De Pover, A; Ebel, N; Eck, MJ; Erdmann, D; Evrot, E; Gaul, C; Hofmann, F; Kopp, N; Kung, AL; Lane, AA; Levine, RL; Marubayashi, S; McKeown, M; Murakami, M; Paranal, RM; Radimerski, T; Régnier, CH; Romanet, V; Sallan, SE; Tiedt, R; Toms, AV; van Bodegom, D; Vangrevelinghe, E; Weigert, O; Weinstock, DM; Yoda, A	1

Other Studies

2 other study(ies) available for isoxazoles and Myeloproliferative Disorders

Article	Year
Heat shock protein 90 inhibitor is synergistic with JAK2 inhibitor and overcomes resistance to JAK2-TKI in human myeloproliferative neoplasm cells. Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Dec-01, Volume: 17, Issue:23 Topics: Animals; Antigens, CD34; Apoptosis; bcl-X Protein; Cell Cycle; Drug Resistance, Neoplasm; Drug Synergism; Hematopoietic Stem Cells; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Janus Kinase 2; Mice; Myeloproliferative Disorders; Proto-Oncogene Proteins c-akt; Pyrimidines; Resorcinols; Signal Transduction; STAT5 Transcription Factor; Sulfonamides; Tumor Cells, Cultured	2011
Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition. The Journal of experimental medicine, 2012, Feb-13, Volume: 209, Issue:2 Topics: Animals; Cell Line, Tumor; Cell Proliferation; DNA Primers; Female; Flow Cytometry; Gene Expression Profiling; HSP90 Heat-Shock Proteins; Humans; Immunoblotting; Immunohistochemistry; Isoxazoles; Janus Kinase 2; Leukemia, B-Cell; Luciferases; Mice; Mice, Inbred BALB C; Mutagenesis; Mutation, Missense; Myeloproliferative Disorders; Phosphorylation; Receptors, Cytokine; Resorcinols; RNA, Small Interfering; Signal Transduction; X-Ray Microtomography	2012

Article

Year

Heat shock protein 90 inhibitor is synergistic with JAK2 inhibitor and overcomes resistance to JAK2-TKI in human myeloproliferative neoplasm cells.

Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Dec-01, Volume: 17, Issue:23

Topics: Animals; Antigens, CD34; Apoptosis; bcl-X Protein; Cell Cycle; Drug Resistance, Neoplasm; Drug Synergism; Hematopoietic Stem Cells; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Janus Kinase 2; Mice; Myeloproliferative Disorders; Proto-Oncogene Proteins c-akt; Pyrimidines; Resorcinols; Signal Transduction; STAT5 Transcription Factor; Sulfonamides; Tumor Cells, Cultured

2011

Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition.

The Journal of experimental medicine, 2012, Feb-13, Volume: 209, Issue:2

Topics: Animals; Cell Line, Tumor; Cell Proliferation; DNA Primers; Female; Flow Cytometry; Gene Expression Profiling; HSP90 Heat-Shock Proteins; Humans; Immunoblotting; Immunohistochemistry; Isoxazoles; Janus Kinase 2; Leukemia, B-Cell; Luciferases; Mice; Mice, Inbred BALB C; Mutagenesis; Mutation, Missense; Myeloproliferative Disorders; Phosphorylation; Receptors, Cytokine; Resorcinols; RNA, Small Interfering; Signal Transduction; X-Ray Microtomography

2012