isoxazoles has been researched along with Muscle Contraction in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (26.09) | 18.7374 |
| 1990's | 8 (34.78) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 4 (17.39) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lobov, GI; Unt, DV | 1 |
| Duthie, KM; Hadoke, PW; Ivy, JR; Kirkby, NS; Lim, WG; McShane, JF; Miller, E; Webb, DJ | 1 |
| Chiba, Y; Misawa, M; Nakazawa, S; Sakai, H; Shinozaki, K; Todoroki, M | 1 |
| Hori, M; Kida, T; Murata, T; Ozaki, H | 1 |
| Clifford, PS; Davis, MJ; Dora, KA; Ella, SR; Gulia, J; Hill, MA; Meininger, GA; Yang, Y | 1 |
| Nylander, O; Sedin, J; Sjöblom, M | 1 |
| Barrish, JC; Bird, E; Chen, P; Chong, S; Gu, Z; Hermsmeier, M; Humphreys, WG; Koplowitz, B; Leith, L; Liu, EC; Marino, A; Mathur, A; Moreland, S; Morrison, RA; Murugesan, N; Spergel, S; Trippodo, N; Waldron, T; Webb, ML; Young, M; Zhang, R | 1 |
| Berardi, F; Colabufo, NA; Lacivita, E; Leopoldo, M; Perrone, R; Tortorella, V | 1 |
| Chaignat, V; Danuser, H; Mevissen, M; Stoffel, MH; Studer, UE; Z'brun, S | 1 |
| Sone, H; Takayanagi, I | 1 |
| Kadokawa, T; Kawashima, K; Sohji, Y; Sone, H; Takayanagi, I | 1 |
| Dannhardt, G; Lambrecht, G; Mutschler, E; Schweiger, J | 1 |
| de Bock, V; Decramer, M; Derom, E; Gayan-Ramirez, G; Gurrieri, G | 1 |
| Akgün, H; Balkan, A; Batu, OS; Erol, K | 1 |
| Goswami, S; Maayani, S; Rienzi, N; Schachter, EN; Zuskin, E | 1 |
| Cadavid, MI; Carotti, A; Carrieri, A; Cid, J; Fontenla, JA; Loza, MI; Lozoya, E; Masaguer, CF; Negreira, J; Raviña, E; Rivas, ME; Rosa, E; Sanz, F; Tristán, H | 1 |
| Diamantis, W; Edelson, J; Gordon, R; Ludwig, BJ; Sofia, RD | 1 |
| Crotti, P; Fracchia, C; Gurrieri, G; Nava, S; Rampulla, C | 1 |
| Decramer, M; Derom, E; Gurrieri, G; Janssens, S; Tjandramaga, TB | 1 |
| Cho, HL; Gilmore, J; Snyder, DW | 1 |
| Carenzi, A; Chiarino, D; Napoletano, M; Reggiani, A; Sala, A; Sala, R | 1 |
| Kadokawa, T; Kawashima, K; Mizuta, H; Naruto, S; Ueda, S; Yoshida, T | 1 |
| Clements, AN; May, TE | 1 |
1 trial(s) available for isoxazoles and Muscle Contraction
| Article | Year |
|---|---|
Effect of a beta 2-agonist (broxaterol) on respiratory muscle strength and endurance in patients with COPD with irreversible airway obstruction.
Topics: Adrenergic beta-Agonists; Aged; Carbon Dioxide; Double-Blind Method; Humans; Isoxazoles; Lung Diseases, Obstructive; Middle Aged; Muscle Contraction; Oxygen; Respiratory Mechanics; Respiratory Muscles | 1992 |
22 other study(ies) available for isoxazoles and Muscle Contraction
| Article | Year |
|---|---|
Protective Effect of Dexamethasone on Lipopolysaccharide-Induced Inhibition of Contractile Function of Isolated Lymphatic Vessels and Nodes.
Topics: Amidines; Animals; Anti-Inflammatory Agents; Benzylamines; Cattle; Cyclooxygenase 2; Dexamethasone; Endothelial Cells; Gene Expression; Isoxazoles; Lipopolysaccharides; Lymph Nodes; Lymphatic Vessels; Male; Muscle Contraction; Muscle, Smooth; Myocytes, Smooth Muscle; Nitric Oxide Synthase Type II; Tissue Culture Techniques | 2018 |
Selective endothelin A receptor antagonism with sitaxentan reduces neointimal lesion size in a mouse model of intraluminal injury.
Topics: Animals; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Femoral Artery; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth, Vascular; Myography; Neointima; Pyrrolidines; Thiophenes | 2015 |
Interleukin-13 augments bronchial smooth muscle contractility with an up-regulation of RhoA protein.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchoalveolar Lavage; Cell Line; Disease Models, Animal; Humans; Interleukin-13; Isoxazoles; Leflunomide; Male; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Signal Transduction; STAT6 Transcription Factor; Up-Regulation | 2009 |
Chronic stimulation of farnesoid X receptor impairs nitric oxide sensitivity of vascular smooth muscle.
Topics: Animals; Cyclic GMP; DNA-Binding Proteins; Endothelium, Vascular; Glyceraldehyde-3-Phosphate Dehydrogenases; Iloprost; Isoxazoles; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Organ Culture Techniques; Rabbits; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors; Vasodilator Agents | 2009 |
Development of an image-based system for measurement of membrane potential, intracellular Ca(2+) and contraction in arteriolar smooth muscle cells.
Topics: Animals; Arterioles; Barbiturates; Calcium; Coumarins; Ethanolamines; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; HEK293 Cells; Humans; Image Processing, Computer-Assisted; In Vitro Techniques; Isoxazoles; Male; Membrane Potentials; Muscle Contraction; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 2010 |
The selective cyclooxygenase-2 inhibitor parecoxib markedly improves the ability of the duodenum to regulate luminal hypertonicity in anaesthetized rats.
Topics: Animals; Cyclooxygenase 2 Inhibitors; Duodenum; Isoxazoles; Male; Models, Animal; Muscle Contraction; Muscle Hypertonia; Muscle, Smooth; Osmolar Concentration; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Regression Analysis; Saline Solution, Hypertonic; Unconsciousness | 2012 |
Biphenylsulfonamide endothelin receptor antagonists. 4. Discovery of N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]- 2-yl]methyl]-N,3,3-trimethylbutanamide (BMS-207940), a highly potent and orally active ET(A) selective
Topics: Administration, Oral; Animals; Blood Pressure; Caco-2 Cells; Carotid Arteries; CHO Cells; Cricetinae; Endothelin Receptor Antagonists; Humans; In Vitro Techniques; Isoxazoles; Macaca fascicularis; Male; Muscle Contraction; Oxazoles; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Structure-Activity Relationship; Sulfonamides | 2003 |
Synthesis and structure-affinity relationships of 1-[omega-(4-aryl-1-piperazinyl)alkyl]-1-aryl ketones as 5-HT(7) receptor ligands.
Topics: Animals; Brain; Cell Line; Cricetinae; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Isoxazoles; Ketones; Ligands; Liver; Muscle Contraction; Muscle, Smooth; Piperazines; Radioligand Assay; Rats; Receptors, Serotonin; Structure-Activity Relationship | 2003 |
Effects of a non-selective COX inhibitor and selective COX-2 inhibitors on contractility of human and porcine ureters in vitro and in vivo.
Topics: Aged; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Data Interpretation, Statistical; Diclofenac; Dose-Response Relationship, Drug; Electric Stimulation; Female; Humans; Immunohistochemistry; In Vitro Techniques; Isoxazoles; Kidney; Kinetics; Male; Muscle Contraction; Muscle, Smooth; Sulfonamides; Swine; Ureter; Ureteral Obstruction | 2008 |
Inhibitory action of 2-(1-,2-benzisoxazol-3-yl)-3-[2-(2-piperidinoethoxy) phenyl]acrylonitrile (SX-284) on acetylcholine release from vagus nerve in guinea pig ileum.
Topics: Acetylcholine; Animals; Choline; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Isoxazoles; Male; Muscle Contraction; Muscle, Smooth; Oxazoles; Tetrodotoxin; Vagus Nerve; Vas Deferens | 1983 |
A possible mechanism of a new antispasmodic drug, 2-(1,2-benzisoxazol-3-yl)-3-[2-(2-piperidinoethoxy) phenyl]acrylonitrile (SX-284).
Topics: Animals; Cecum; Gastric Fundus; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Isoxazoles; Male; Muscle Contraction; Muscle, Smooth; Oxazoles; Parasympatholytics; Phrenic Nerve; Trachea; Urinary Bladder | 1982 |
Synthesis and muscarinic activity of isoxazole-substituted 1,2,5,6-tetrahydropyridines.
Topics: Animals; Cholinergic Agents; Guinea Pigs; In Vitro Techniques; Isoxazoles; Male; Muscle Contraction; Muscle, Smooth; Pyridines; Rabbits | 1994 |
Broxaterol increases force output of fatigued canine diaphragm more than salbutamol.
Topics: Adrenergic beta-Agonists; Albuterol; Animals; Diaphragm; Dogs; Isoxazoles; Muscle Contraction; Muscle Fatigue | 1997 |
New beta-diketone and 3,5-dimethyl isoxazole derivatives of theophylline as potential bronchodilator agents.
Topics: Acetylcholine; Animals; Bronchi; Bronchodilator Agents; Chemical Phenomena; Chemistry, Physical; Female; Guinea Pigs; Histamine; Histamine Antagonists; In Vitro Techniques; Isoxazoles; Male; Muscle Contraction; Muscle, Smooth; Theophylline | 1998 |
Pharmacologic characterization of latex extracts by isolated guinea pig tracheal tissue.
Topics: Animals; Arachidonic Acids; Atropine; Capsaicin; Cholinergic Antagonists; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Gallic Acid; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Isoxazoles; Latex; Leukotriene Antagonists; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Pyrilamine; Trachea | 1998 |
Conformationally constrained butyrophenones with mixed dopaminergic (D(2)) and serotoninergic (5-HT(2A), 5-HT(2C)) affinities: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo- and -thienocycloalkanones as putative atypical an
Topics: Animals; Antipsychotic Agents; Aorta, Thoracic; Brain; Catalepsy; Cattle; Dopamine Agents; In Vitro Techniques; Isoxazoles; Male; Mice; Models, Molecular; Motor Activity; Muscle Contraction; Muscle, Smooth, Vascular; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin Agents; Structure-Activity Relationship; Thiophenes | 1999 |
Pharmacological properties of 2,3-dihydro-9H-isoxazolo[3,2-b]-quinazolin-9-one (W-2429. Part 2: General pharmacological investigation.
Topics: Anesthetics, Local; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents, Tricyclic; Antitussive Agents; Cats; Diuresis; Dogs; Enzyme Induction; Female; Gastrointestinal Hemorrhage; Gastrointestinal Motility; Guinea Pigs; Hemodynamics; Isoxazoles; Male; Mice; Motor Activity; Muscle Contraction; Muscle, Smooth; Oxazoles; Postural Balance; Prostaglandin-Endoperoxide Synthases; Quinazolines; Rabbits; Rats; Respiration; Sleep; Stomach Ulcer; Time Factors | 1977 |
Effects of broxaterol and theophylline on fatigued canine diaphragm in vivo. A randomized, controlled study.
Topics: Adrenergic beta-Agonists; Animals; Diaphragm; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Isoxazoles; Muscle Contraction; Random Allocation; Theophylline | 1992 |
Endogenously formed leukotriene C4 activates LTC4 receptors in guinea pig tracheal strips.
Topics: Acetophenones; Animals; Antimetabolites; Benzyl Compounds; Carbachol; Guinea Pigs; Hydroxamic Acids; In Vitro Techniques; Indoles; Isoxazoles; Leukotriene Antagonists; Male; Muscle Contraction; Muscle, Smooth; Ovalbumin; Phenylcarbamates; Receptors, Immunologic; Receptors, Leukotriene; SRS-A; Sulfonamides; Tetrazoles; Tosyl Compounds; Trachea | 1991 |
New isoxazole derivatives provided with antihypertensive activity.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Chemical Phenomena; Chemistry; Clonidine; In Vitro Techniques; Isoxazoles; Magnetic Resonance Spectroscopy; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxazoles; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Vas Deferens; Yohimbine | 1989 |
Synthesis and spasmolytic activity of aminoalkyl 2-substituted-2-(1,2-benzisoxazol-3-yl)acetates.
Topics: Animals; Chemical Phenomena; Chemistry; Guinea Pigs; In Vitro Techniques; Isoxazoles; Male; Muscle Contraction; Oxazoles; Parasympatholytics | 1987 |
Pharmacological studies on a locust neuromuscular preparation.
Topics: Alkaloids; Amines; Amino Acids; Animals; Butyrates; Dose-Response Relationship, Drug; Fluorides; Glutamates; Grasshoppers; Indoles; Isoxazoles; Leg; Male; Muscle Contraction; Muscles; Neuromuscular Junction; Phenothiazines; Propionates; Pyrrolidinones; Receptors, Drug; Serotonin; Structure-Activity Relationship; Synapses; Synaptic Transmission; Tryptamines | 1974 |