Page last updated: 2024-08-21

isoxazoles and Kidney Diseases

isoxazoles has been researched along with Kidney Diseases in 48 studies

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19903 (6.25)18.7374
1990's9 (18.75)18.2507
2000's18 (37.50)29.6817
2010's18 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bae, EH; Choi, HI; Kim, CS; Kim, DH; Kim, SW; Ma, SK; Park, JS1
Akbaş, SH; Akkaya, B; Akman, S; Cağla Doğan, S; Colak, D; Comak, E; Dinçkan, A; Koyun, M; Mutlu, D; Mutlu, E; Sağlık, I; Süleymanlar, G; Uslu Gökçeoğlu, A1
Abrahams, AC; Kemperman, H; Verhoeven, Y1
Chen, JS; Cheng, DR; Ji, SM; Li, X; Liu, ZH; Wen, JQ; Wu, D; Xie, KN; Zhang, MC1
Boucher, A; Collette, S; Dandavino, R; Lamarche, C; Senécal, L; Tran, D; Vallée, M1
Bodson-Clermont, P; Cardinal, H; Fortin, MC; Girardin, C; Hébert, MJ; Lévesque, R; Pâquet, MR; Renoult, E; Simard-Meilleur, MC; St-Louis, G1
Rintala, JM; Rintala, SE; Savikko, J; von Willebrand, E1
Bucher, M; Höcherl, K; Schmidt, C1
Harris, MT; Wu, JK1
Cooper, AJ; Hanigan, MH; Townsend, DM1
Bloudícková, S; Honsová, E; Lodererová, A; Rajnoch, J; Viklický, O1
Egli, A; Helmersen, DS; Hirsch, HH; Johnson, A; Taub, K1
Basdemir, G; Bayirli Turan, D; Dheir, H; Gurkan, A; Kacar, S; Sahin, S; Turunc, V; Uyar, M1
Chon, WJ; Josephson, MA1
Chen, B; Huang, WH; Lee, AR; Media, J; Shaw, J; Valeriote, FA1
Basu, G; John, GT; Mani, SE; Manipadam, MT; Mohapatra, A1
Barton, M1
Gray, M; Leonard, N; McCrory, R; Smyth, J; Woodman, A1
Butts, RJ; Savage, AJ; Uber, WE1
Suzuki, Y1
Cheong, HI; Ha, IS; Ha, JW; Jung, YH; Kang, HG; Kim, SJ; Moon, KC1
Dhir, V; Krishnan, S; Nada, R; Pinto, B1
Bruno, MK; Cohen, SD; Hill, DW; Horton, RA; Roberts, JC; Stern, ST1
Atwood, W; Foster, P; Garfinkel, M; Gillen, D; Harland, R; Javaid, B; Josephson, MA; Kadambi, PV; Meehan, SM; Millis, JM; Thistlewaite, JR; Williams, JW1
Sugii, S1
Donauer, J; Geyer, M; Schenk, T; Schwertfeger, E; Teschner, S; Walz, G; Wilpert, J1
Chandraker, A; Josephson, MA; Randhawa, PS; Williams, JW1
Coyne, T; Dhaun, N; Goddard, J; Kramer, W; Melville, V; Stavros, F; Swan, S; Webb, DJ1
Cointault, O; Esposito, L; Faguer, S; Guilbeau-Frugier, C; Guitard, J; Hirsch, HH; Kamar, N; Lavit, M; Mengelle, C; Modesto, A; Ribes, D; Rostaing, L1
Bascands, JL; Calise, D; Chun, J; Grès, S; Guigné, C; Klein, J; Neau, E; Pradère, JP; Saulnier-Blache, JS; Schanstra, JP; Valet, P1
Saito, E; Suwa, A; Suzuki, Y; Wakabayashi, T1
Heykants, J; Mannens, G; Meuldermans, W; Snoeck, E1
Foster, JR; Fowler, LM; Lock, EA1
Eger, EI; Kandel, L; Kerschmann, RL; Laster, MJ; Martin, JL; Reed, GF1
Eger, EI; Gong, D; Ionescu, P; Kerschmann, RL; Laster, MJ; Weiskopf, RB1
Jones, TW; Lau, SS; Monks, TJ; Peters, MM1
Boveris, A; Camandola, S; Cutrín, JC; Poli, G; Pompella, A; Zingaro, B1
Chen, H; Christ, DD; Davies, MH; Gan, LS; Gemzik, B; Gerson, RJ; Haley, PJ; Krahn, DF; Markwalder, JA; Meunier, PC; Miwa, GT; Mutlib, AE; Robertson, RT; Seitz, SP1
Kallenberg, CG; Stegeman, CA; Tervaert, JW1
Hanigan, MH; Townsend, DM1
Horvath, JJ; Witmer, CM; Witz, G1
Jones, TW; Lau, SS; Lo, HH; Mertens, JJ; Monks, TJ; Temmink, JH; van Bladeren, PJ1
Brown, PI; Nicoll, DW; Rankin, GO; Shih, HC; Teets, VJ; Yang, DJ1
Furukawa, H; Ichiki, T; Kodama, R; Kuwata, M; Nasu, Y; Satoh, K; Sone, H; Yamashita, K1
Davis, ME1
Dahl, JE; Dybing, E; Nelson, SD; Omichinski, JG; Søderlund, EJ1
Mertens, JJ; Spenkelink, B; Temmink, JH; van Bladeren, PJ; van Doorn, WJ; Weijnen, JG1

Reviews

9 review(s) available for isoxazoles and Kidney Diseases

ArticleYear
Use of leflunomide in the treatment of polyomavirus BK-associated nephropathy.
    The Annals of pharmacotherapy, 2008, Volume: 42, Issue:11

    Topics: BK Virus; Humans; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Polyomavirus Infections; Tumor Virus Infections

2008
Leflunomide in renal transplantation.
    Expert review of clinical immunology, 2011, Volume: 7, Issue:3

    Topics: Humans; Immunosuppressive Agents; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide

2011
Endothelin antagonism and reversal of proteinuric renal disease in humans.
    Contributions to nephrology, 2011, Volume: 172

    Topics: Endothelins; Humans; Isoxazoles; Kidney Diseases; Phenylpropionates; Proteinuria; Pyridines; Pyrimidines; Receptor, Endothelin A; Thiophenes

2011
Leflunomide therapy for BK virus allograft nephropathy after pediatric kidney transplantation.
    Pediatric transplantation, 2013, Volume: 17, Issue:2

    Topics: Antiviral Agents; BK Virus; Child; Female; Humans; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Polyomavirus Infections; Postoperative Complications; Tumor Virus Infections

2013
Leflunomide-induced DRESS syndrome with renal involvement and vasculitis.
    Clinical rheumatology, 2013, Volume: 32, Issue:5

    Topics: Antirheumatic Agents; Biopsy; Drug Hypersensitivity Syndrome; Eosinophilia; Erythema; Exanthema; Humans; Isoxazoles; Kidney Diseases; Leflunomide; Male; Middle Aged; Nephritis; Time Factors; Treatment Outcome; Vascular Diseases

2013
[Adverse effects of DMARDs in treatment of rheumatoid arthritis].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 1

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Female; Gold Sodium Thiomalate; Hematologic Diseases; Humans; Isoxazoles; Kidney Diseases; Leflunomide; Lung Diseases, Interstitial; Male; Methotrexate; Reproduction; Sulfasalazine

2005
Polyomavirus-associated nephropathy: update on antiviral strategies.
    Transplant infectious disease : an official journal of the Transplantation Society, 2006, Volume: 8, Issue:2

    Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Humans; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Organophosphonates; Polyomavirus; Polyomavirus Infections; Quinolones

2006
[Adverse effects of conventional DMARDs and biologic DMARDs].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Antibodies, Monoclonal; Antirheumatic Agents; Chemical and Drug Induced Liver Injury; Cysteine; Drug Eruptions; Drug Hypersensitivity; Hematologic Diseases; Humans; Immune System Diseases; Infliximab; Isoxazoles; Kidney Diseases; Leflunomide; Lung Diseases; Methotrexate

2007
Novel therapies for anti-neutrophil cytoplasmic antibody-associated vasculitis.
    Current opinion in nephrology and hypertension, 2001, Volume: 10, Issue:2

    Topics: Antibodies, Antineutrophil Cytoplasmic; Antilymphocyte Serum; Cyclophosphamide; Guanidines; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Intercellular Adhesion Molecule-1; Isoxazoles; Kidney Diseases; Leflunomide; Methotrexate; Mycophenolic Acid; Prednisone; Remission Induction; Trimethoprim, Sulfamethoxazole Drug Combination; Tumor Necrosis Factor-alpha; Vasculitis

2001

Other Studies

39 other study(ies) available for isoxazoles and Kidney Diseases

ArticleYear
Src-mediated crosstalk between FXR and YAP protects against renal fibrosis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:10

    Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Cycle Proteins; Epithelial Cells; Fibrosis; Humans; Isoxazoles; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Proto-Oncogene Mas; Receptors, Cytoplasmic and Nuclear; Signal Transduction; src-Family Kinases; YAP-Signaling Proteins

2019
[BK virus infections in pediatric kidney transplant recipients].
    Mikrobiyoloji bulteni, 2013, Volume: 47, Issue:3

    Topics: Adolescent; Antiviral Agents; BK Virus; Child; Cidofovir; Cytosine; DNA, Viral; Female; Graft Rejection; Humans; Immunosuppressive Agents; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Male; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections; Turkey

2013
Falsely decreased ionized calcium levels in kidney transplant recipients with polyomavirus-associated nephropathy treated with leflunomide.
    Transplant international : official journal of the European Society for Organ Transplantation, 2015, Volume: 28, Issue:7

    Topics: Aged; Antiviral Agents; Biomarkers; BK Virus; Calcium; Female; Humans; Immunocompromised Host; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Polyomavirus Infections

2015
BK Virus-Associated Nephropathy with Plasma Cell-Rich Infiltrates Treated by Bortezomib-Based Regimen.
    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2015, Volume: 13, Issue:6

    Topics: Adult; Antineoplastic Agents; BK Virus; Bortezomib; Female; Humans; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Plasma Cells; Polyomavirus Infections; Postoperative Complications; Tacrolimus; Tumor Virus Infections

2015
Treatment of Polyomavirus-Associated Nephropathy With the Association of Sirolimus and Leflunomide.
    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2015, Volume: 13, Issue:6

    Topics: Antiviral Agents; Humans; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Polyomavirus Infections; Retrospective Studies; Sirolimus

2015
Stabilization of renal function after the first year of follow-up in kidney transplant recipients treated for significant BK polyomavirus infection or BK polyomavirus-associated nephropathy.
    Transplant infectious disease : an official journal of the Transplantation Society, 2017, Volume: 19, Issue:3

    Topics: Adult; Allografts; Antiviral Agents; Biopsy; BK Virus; DNA, Viral; Female; Follow-Up Studies; Glomerular Filtration Rate; Graft Survival; Humans; Immunohistochemistry; Immunosuppression Therapy; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Male; Middle Aged; Polyomavirus Infections; Retrospective Studies; Transplant Recipients; Transplantation, Homologous; Tumor Virus Infections; Viremia; Virus Replication

2017
FK778 ameliorates post-transplant expression of fibrogenic growth factors and development of chronic rejection changes in rat kidney allografts.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:11

    Topics: Alkynes; Animals; Calcineurin Inhibitors; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Graft Rejection; Immunosuppressive Agents; Isoxazoles; Kidney Diseases; Kidney Transplantation; Male; Nitriles; Platelet-Derived Growth Factor; Rats; Rats, Inbred WF; Risk Factors; Tacrolimus; Transforming Growth Factor beta; Transplantation, Homologous

2008
COX-2 inhibition attenuates endotoxin-induced downregulation of organic anion transporters in the rat renal cortex.
    Kidney international, 2009, Volume: 75, Issue:4

    Topics: Acute Disease; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Down-Regulation; Isoxazoles; Kidney Cortex; Kidney Diseases; Lipopolysaccharides; Male; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Sprague-Dawley

2009
Metabolism of cisplatin to a nephrotoxin.
    Toxicology, 2009, Mar-29, Volume: 257, Issue:3

    Topics: Animals; Antineoplastic Agents; Biotransformation; Carbon-Sulfur Lyases; Cells, Cultured; Cisplatin; Enzyme Inhibitors; gamma-Glutamyltransferase; Humans; Isoxazoles; Kidney Diseases; Lyases; Mice; Rats; Transaminases

2009
Leflunomide derivate FK 778 in accelerated renal injury in transgenic rat.
    Folia biologica, 2010, Volume: 56, Issue:2

    Topics: Alkynes; Animals; Blood Pressure; Disease Models, Animal; Immunosuppressive Agents; Isoxazoles; Kidney; Kidney Diseases; Leflunomide; Male; Nitriles; Placebos; Rats; Rats, Transgenic; Reperfusion Injury

2010
Renal failure five years after lung transplantation due to polyomavirus BK-associated nephropathy.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2010, Volume: 10, Issue:10

    Topics: Adult; Aged; Cidofovir; Cytosine; Female; Humans; Isoxazoles; Kidney Diseases; Leflunomide; Lung Transplantation; Male; Middle Aged; Mycophenolic Acid; Organophosphonates; Polyomavirus Infections; Prednisone; Renal Insufficiency; Tacrolimus; TOR Serine-Threonine Kinases

2010
Intensive polyoma virus nephropathy treatment as a preferable approach for graft surveillance.
    Transplantation proceedings, 2011, Volume: 43, Issue:3

    Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Female; Graft Rejection; Graft Survival; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Tacrolimus

2011
The small-molecule TNF-alpha modulator, UTL-5g, reduces side effects induced by cisplatin and enhances the therapeutic effect of cisplatin in vivo.
    Journal of experimental therapeutics & oncology, 2011, Volume: 9, Issue:2

    Topics: Animals; Antineoplastic Agents; Blood Urea Nitrogen; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Cisplatin; Colonic Neoplasms; Female; Hematologic Diseases; Humans; Isoxazoles; Kidney Diseases; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Mice, SCID; Platelet Count; Toxicity Tests, Acute; Tumor Necrosis Factor-alpha

2011
Leflunomide with low-dose everolimus for treatment of Kaposi's sarcoma in a renal allograft recipient.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:10

    Topics: Antineoplastic Agents; Everolimus; Humans; Immunosuppressive Agents; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Male; Middle Aged; Proto-Oncogene Proteins c-akt; Sarcoma, Kaposi; Sirolimus; Transplantation, Homologous; Treatment Outcome

2011
Native kidney BK virus nephropathy associated with chronic lymphocytic leukaemia.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2012, Volume: 27, Issue:3

    Topics: Aged; BK Virus; DNA, Viral; Humans; Immunosuppressive Agents; Isoxazoles; Kidney Diseases; Leflunomide; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Polymerase Chain Reaction; Polyomavirus Infections; Prognosis; Tumor Virus Infections

2012
Treatment of BK viremia in a pediatric heart transplant recipient.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2012, Volume: 31, Issue:5

    Topics: Antiviral Agents; BK Virus; Child; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Isoxazoles; Kidney; Kidney Diseases; Leflunomide; Opportunistic Infections; Tacrolimus; Treatment Outcome; Viral Load; Viremia

2012
[Anti-rheumatic drugs].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 6

    Topics: Antirheumatic Agents; Cysteine; Hematologic Diseases; Humans; Hypersensitivity; Infections; Isoxazoles; Kidney Diseases; Leflunomide; Liver Neoplasms; Lung Diseases; Methotrexate

2012
Contribution of acetaminophen-cysteine to acetaminophen nephrotoxicity II. Possible involvement of the gamma-glutamyl cycle.
    Toxicology and applied pharmacology, 2005, Jan-15, Volume: 202, Issue:2

    Topics: Acetaminophen; Animals; Cell Membrane; Chromatography, High Pressure Liquid; Cysteine; Dipeptides; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Glutathione; Glutathione Transferase; Injections, Intraperitoneal; Isoxazoles; Kidney Diseases; Kidney Tubules, Proximal; Male; Mass Spectrometry; Mice; Mice, Inbred Strains; Microvilli; Molecular Structure; Toxicity Tests

2005
Leflunomide for polyomavirus type BK nephropathy.
    The New England journal of medicine, 2005, Mar-17, Volume: 352, Issue:11

    Topics: Aniline Compounds; Antiviral Agents; BK Virus; Crotonates; Humans; Hydroxybutyrates; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Nitriles; Polyomavirus Infections; Toluidines; Tumor Virus Infections

2005
Remission of polyomavirus-induced graft nephropathy treated with low-dose leflunomide.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2006, Volume: 21, Issue:7

    Topics: Adult; Antiviral Agents; Humans; Immunoglobulins; Immunosuppressive Agents; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Middle Aged; Polyomavirus; Polyomavirus Infections; Remission Induction; Time Factors

2006
The pharmacokinetic profile of sitaxsentan, a selective endothelin receptor antagonist, in varying degrees of renal impairment.
    British journal of clinical pharmacology, 2007, Volume: 64, Issue:6

    Topics: Adolescent; Adult; Aged; Endothelin A Receptor Antagonists; Female; Humans; Isoxazoles; Kidney Diseases; Male; Metabolic Clearance Rate; Middle Aged; Receptor, Endothelin A; Thiophenes

2007
Leflunomide treatment for polyomavirus BK-associated nephropathy after kidney transplantation.
    Transplant international : official journal of the European Society for Organ Transplantation, 2007, Volume: 20, Issue:11

    Topics: Adult; Antiviral Agents; BK Virus; Female; Humans; Immunosuppression Therapy; Isoxazoles; Kidney Diseases; Kidney Transplantation; Leflunomide; Male; Middle Aged; Polyomavirus Infections; Transplantation, Homologous; Tumor Virus Infections

2007
LPA1 receptor activation promotes renal interstitial fibrosis.
    Journal of the American Society of Nephrology : JASN, 2007, Volume: 18, Issue:12

    Topics: Animals; Culture Media, Conditioned; Fibrosis; Humans; Isoxazoles; Kidney; Kidney Diseases; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phospholipids; Propionates; Receptors, Lysophosphatidic Acid; Transforming Growth Factor beta; Ureter

2007
Plasma protein binding of risperidone and its distribution in blood.
    Psychopharmacology, 1994, Volume: 114, Issue:4

    Topics: Adult; Aged; Animals; Antipsychotic Agents; Blood Cells; Blood Proteins; Dogs; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Isoxazoles; Kidney Diseases; Liver Diseases; Male; Middle Aged; Orosomucoid; Paliperidone Palmitate; Piperidines; Protein Binding; Pyrimidines; Rats; Rats, Wistar; Risperidone; Serum Albumin

1994
Effect of ascorbic acid, acivicin and probenecid on the nephrotoxicity of 4-aminophenol in the Fischer 344 rat.
    Archives of toxicology, 1993, Volume: 67, Issue:9

    Topics: Aminophenols; Animals; Antimetabolites; Ascorbic Acid; Isoxazoles; Kidney; Kidney Diseases; Kidney Function Tests; Liver; Male; Probenecid; Rats; Rats, Inbred F344

1993
Metabolism of compound A by renal cysteine-S-conjugate beta-lyase is not the mechanism of compound A-induced renal injury in the rat.
    Anesthesia and analgesia, 1996, Volume: 82, Issue:4

    Topics: Aminooxyacetic Acid; Anesthetics, Inhalation; Animals; Buthionine Sulfoximine; Carbon-Sulfur Lyases; Enzyme Inhibitors; Ethers; Glutathione; Hydrocarbons, Fluorinated; Isoxazoles; Kidney; Kidney Diseases; Lyases; Male; Methionine Sulfoximine; Methyl Ethers; Rats; Rats, Wistar; Sevoflurane

1996
Quantitative differences in the production and toxicity of CF2=BrCl versus CH2F-O-C(=CF2)(CF3) (compound A): the safety of halothane does not indicate the safety of sevoflurane.
    Anesthesia and analgesia, 1997, Volume: 85, Issue:5

    Topics: Absorption; Aminooxyacetic Acid; Anesthetics, Inhalation; Animals; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Ethers; Halothane; Humans; Hydrocarbons, Fluorinated; Hydrocarbons, Halogenated; Isoxazoles; Kidney Diseases; Lyases; Methyl Ethers; Rats; Rats, Inbred F344; Rats, Wistar; Sevoflurane

1997
Cytotoxicity and cell-proliferation induced by the nephrocarcinogen hydroquinone and its nephrotoxic metabolite 2,3,5-(tris-glutathion-S-yl)hydroquinone.
    Carcinogenesis, 1997, Volume: 18, Issue:12

    Topics: Animals; Carcinogens; Cell Division; Cell Survival; gamma-Glutamyltransferase; Glutathione; Hydroquinones; Isoxazoles; Kidney; Kidney Diseases; Kidney Neoplasms; Male; Rats; Rats, Inbred F344

1997
Contribution of gamma glutamyl transpeptidase to oxidative damage of ischemic rat kidney.
    Kidney international, 2000, Volume: 57, Issue:2

    Topics: Animals; Cell Size; Cytosol; Enzyme Activation; Enzyme Inhibitors; gamma-Glutamyltransferase; Ischemia; Isoxazoles; Kidney Diseases; Kidney Tubules; Lipid Peroxidation; Male; Microsomes; Oxidative Stress; Rats; Rats, Wistar; Renal Circulation

2000
The species-dependent metabolism of efavirenz produces a nephrotoxic glutathione conjugate in rats.
    Toxicology and applied pharmacology, 2000, Nov-15, Volume: 169, Issue:1

    Topics: Alkynes; Animals; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Enzyme Inhibitors; Epithelial Cells; Gas Chromatography-Mass Spectrometry; Glutathione; Haplorhini; Humans; Isoxazoles; Kidney Diseases; Kidney Tubules; Male; Necrosis; Oxazines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Species Specificity

2000
Inhibition of gamma-glutamyl transpeptidase or cysteine S-conjugate beta-lyase activity blocks the nephrotoxicity of cisplatin in mice.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:1

    Topics: Aminooxyacetic Acid; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Blood Urea Nitrogen; Body Weight; Carbon-Sulfur Lyases; Cisplatin; Enzyme Inhibitors; gamma-Glutamyltransferase; Isoxazoles; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Platinum; Survival Analysis

2002
Valdecoxib (Bextra)--a new cox-2 inhibitor.
    The Medical letter on drugs and therapeutics, 2002, Apr-29, Volume: 44, Issue:1129

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Humans; Isoxazoles; Kidney Diseases; Osteoarthritis; Peptic Ulcer; Sulfonamides

2002
Nephrotoxicity of the 1:1 acrolein-glutathione adduct in the rat.
    Toxicology and applied pharmacology, 1992, Volume: 117, Issue:2

    Topics: Acrolein; Animals; Disulfiram; Glutathione; Isoxazoles; Kidney Diseases; Kidney Tubules, Proximal; Male; Probenecid; Pyrazoles; Rats; Rats, Sprague-Dawley

1992
Inhibition of gamma-glutamyl transpeptidase potentiates the nephrotoxicity of glutathione-conjugated chlorohydroquinones.
    Toxicology and applied pharmacology, 1991, Volume: 110, Issue:1

    Topics: Animals; Ascorbic Acid; Chloranil; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Synergism; Electrochemistry; gamma-Glutamyltransferase; Glutathione; Isoxazoles; Kidney Cortex; Kidney Diseases; Kidney Tubular Necrosis, Acute; Male; Oxidation-Reduction; Rats; Rats, Inbred Strains

1991
N-(3,5-dichlorophenyl)succinimide nephrotoxicity: evidence against the formation of nephrotoxic glutathione or cysteine conjugates.
    Toxicology, 1991, Volume: 68, Issue:3

    Topics: Aminooxyacetic Acid; Animals; Biotransformation; Cysteine; Fungicides, Industrial; gamma-Glutamyltransferase; Glutathione; In Vitro Techniques; Isoxazoles; Kidney Diseases; Male; Rats; Rats, Inbred F344; Succinimides

1991
[Fifty two-week chronic oral toxicity study of mofezolac (N-22) in rats].
    The Journal of toxicological sciences, 1990, Volume: 15 Suppl 2

    Topics: Administration, Oral; Anemia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Female; Gastrointestinal Diseases; Isoxazoles; Kidney Diseases; Liver; Male; Rats; Rats, Inbred Strains

1990
Effects of AT-125 on the nephrotoxicity of hexachloro-1,3-butadiene in rats.
    Toxicology and applied pharmacology, 1988, Volume: 95, Issue:1

    Topics: Animals; Butadienes; gamma-Glutamyltransferase; Glycosuria; Isoxazoles; Kidney Diseases; Kidney Function Tests; Male; Oxazoles; Rats; Rats, Inbred Strains; Urine

1988
Nephrotoxicity of selectively deuterated and methylated analogues of Tris-BP and Bis-BP in the rat.
    Pharmacology & toxicology, 1988, Volume: 62, Issue:3

    Topics: Animals; Blood Urea Nitrogen; Body Weight; Creatinine; Gas Chromatography-Mass Spectrometry; Glutathione; Isoxazoles; Kidney Diseases; Male; Methylation; Necrosis; Organ Size; Organophosphates; Organophosphorus Compounds; Probenecid; Rats; Rats, Inbred Strains

1988
Differential toxicity as a result of apical and basolateral treatment of LLC-PK1 monolayers with S-(1,2,3,4,4-pentachlorobutadienyl)glutathione and N-acetyl-S-(1,2,3,4,4-pentachlorobutadienyl)-L-cysteine.
    Chemico-biological interactions, 1988, Volume: 65, Issue:3

    Topics: Acetylcysteine; Aminooxyacetic Acid; Animals; Anion Transport Proteins; Anions; Biological Transport; Butadienes; Carrier Proteins; Cations; Cell Line; Cell Survival; Epithelial Cells; Epithelium; Glutathione; Isoxazoles; Kidney; Kidney Diseases; p-Aminohippuric Acid; Swine; Tetraethylammonium; Tetraethylammonium Compounds

1988