Page last updated: 2024-08-21

isoxazoles and Innate Inflammatory Response

isoxazoles has been researched along with Innate Inflammatory Response in 85 studies

Research

Studies (85)

TimeframeStudies, this research(%)All Research%
pre-19904 (4.71)18.7374
1990's2 (2.35)18.2507
2000's16 (18.82)29.6817
2010's54 (63.53)24.3611
2020's9 (10.59)2.80

Authors

AuthorsStudies
Li, M; Zheng, Z1
Jin, X; Qin, J; Su, X; Zhao, J1
Chen, Q; Guo, Y; Min, S; Wu, B1
Chen, Z; He, S; Jiang, W; Xue, C; Zhang, X; Zhou, L1
Bornfleth, P; Bukowska, A; Gardemann, A; Goette, A; Isermann, B; Peter, D; Schild, L; Walles, T; Wiese-Rischke, C1
Nagaraju, B; Prasanna, B; Seelam, N; Shanmukhakumar, JV; Subbaiah, T1
Huang, JM; Jiang, WX; Lv, ZT; Nie, MB; Zhang, B1
Cui, L; Li, C; Wang, S; Wang, X; Yan, Z; Zhang, Y; Zheng, Y1
Abbasi, S; Abd El-Wahab, A; Abdallah, M; Abebe, G; Aca-Aca, G; Adama, S; Adefegha, SA; Adidigue-Ndiome, R; Adiseshaiah, P; Adrario, E; Aghajanian, C; Agnese, W; Ahmad, A; Ahmad, I; Ahmed, MFE; Akcay, OF; Akinmoladun, AC; Akutagawa, T; Alakavuklar, MA; Álava-Rabasa, S; Albaladejo-Florín, MJ; Alexandra, AJE; Alfawares, R; Alferiev, IS; Alghamdi, HS; Ali, I; Allard, B; Allen, JD; Almada, E; Alobaid, A; Alonso, GL; Alqahtani, YS; Alqarawi, W; Alsaleh, H; Alyami, BA; Amaral, BPD; Amaro, JT; Amin, SAW; Amodio, E; Amoo, ZA; Andia Biraro, I; Angiolella, L; Anheyer, D; Anlay, DZ; Annex, BH; Antonio-Aguirre, B; Apple, S; Arbuznikov, AV; Arinsoy, T; Armstrong, DK; Ash, S; Aslam, M; Asrie, F; Astur, DC; Atzrodt, J; Au, DW; Aucoin, M; Auerbach, EJ; Azarian, S; Ba, D; Bai, Z; Baisch, PRM; Balkissou, AD; Baltzopoulos, V; Banaszewski, M; Banerjee, S; Bao, Y; Baradwan, A; Barandika, JF; Barger, PM; Barion, MRL; Barrett, CD; Basudan, AM; Baur, LE; Baz-Rodríguez, SA; Beamer, P; Beaulant, A; Becker, DF; Beckers, C; Bedel, J; Bedlack, R; Bermúdez de Castro, JM; Berry, JD; Berthier, C; Bhattacharya, D; Biadgo, B; Bianco, G; Bianco, M; Bibi, S; Bigliardi, AP; Billheimer, D; Birnie, DH; Biswas, K; Blair, HC; Bognetti, P; Bolan, PJ; Bolla, JR; Bolze, A; Bonnaillie, P; Borlimi, R; Bórquez, J; Bottari, NB; Boulleys-Nana, JR; Brighetti, G; Brodeur, GM; Budnyak, T; Budnyk, S; Bukirwa, VD; Bulman, DM; Burm, R; Busman-Sahay, K; Butcher, TW; Cai, C; Cai, H; Cai, L; Cairati, M; Calvano, CD; Camacho-Ordóñez, A; Camela, E; Cameron, T; Campbell, BS; Cansian, RL; Cao, Y; Caporale, AS; Carciofi, AC; Cardozo, V; Carè, J; Carlos, AF; Carozza, R; Carroll, CJW; Carsetti, A; Carubelli, V; Casarotta, E; Casas, M; Caselli, G; Castillo-Lora, J; Cataldi, TRI; Cavalcante, ELB; Cavaleiro, A; Cayci, Z; Cebrián-Tarancón, C; Cedrone, E; Cella, D; Cereda, C; Ceretti, A; Ceroni, M; Cha, YH; Chai, X; Chang, EF; Chang, TS; Chanteux, H; Chao, M; Chaplin, BP; Chaturvedi, S; Chaturvedi, V; Chaudhary, DK; Chen, A; Chen, C; Chen, HY; Chen, J; Chen, JJ; Chen, K; Chen, L; Chen, Q; Chen, R; Chen, SY; Chen, TY; Chen, WM; Chen, X; Chen, Y; Cheng, G; Cheng, GJ; Cheng, J; Cheng, YH; Cheon, HG; Chew, KW; Chhoker, S; Chiu, WN; Choi, ES; Choi, MJ; Choi, SD; Chokshi, S; Chorny, M; Chu, KI; Chu, WJ; Church, AL; Cirrincione, A; Clamp, AR; Cleff, MB; Cohen, M; Coleman, RL; Collins, SL; Colombo, N; Conduit, N; Cong, WL; Connelly, MA; Connor, J; Cooley, K; Correa Ramos Leal, I; Cose, S; Costantino, C; Cottrell, M; Cui, L; Cundall, J; Cutaia, C; Cutler, CW; Cuypers, ML; da Silva Júnior, FMR; Dahal, RH; Damiani, E; Damtie, D; Dan-Li, W; Dang, Z; Dasa, SSK; Davin, A; Davis, DR; de Andrade, CM; de Jong, PL; de Oliveira, D; de Paula Dorigam, JC; Dean, A; Deepa, M; Delatour, C; Dell'Aiera, S; Delley, MF; den Boer, RB; Deng, L; Deng, Q; Depner, RM; Derdau, V; Derici, U; DeSantis, AJ; Desmarini, D; Diffo-Sonkoue, L; Divizia, M; Djenabou, A; Djordjevic, JT; Dobrovolskaia, MA; Domizi, R; Donati, A; Dong, Y; Dos Santos, M; Dos Santos, MP; Douglas, RG; Duarte, PF; Dullaart, RPF; Duscha, BD; Edwards, LA; Edwards, TE; Eichenwald, EC; El-Baba, TJ; Elashiry, M; Elashiry, MM; Elashry, SH; Elliott, A; Elsayed, R; Emerson, MS; Emmanuel, YO; Emory, TH; Endale-Mangamba, LM; Enten, GA; Estefanía-Fernández, K; Estes, JD; Estrada-Mena, FJ; Evans, S; Ezra, L; Faria de, RO; Farraj, AK; Favre, C; Feng, B; Feng, J; Feng, L; Feng, W; Feng, X; Feng, Z; Fernandes, CLF; Fernández-Cuadros, ME; Fernie, AR; Ferrari, D; Florindo, PR; Fong, PC; Fontes, EPB; Fontinha, D; Fornari, VJ; Fox, NP; Fu, Q; Fujitaka, Y; Fukuhara, K; Fumeaux, T; Fuqua, C; Fustinoni, S; Gabbanelli, V; Gaikwad, S; Gall, ET; Galli, A; Gancedo, MA; Gandhi, MM; Gao, D; Gao, K; Gao, M; Gao, Q; Gao, X; Gao, Y; Gaponenko, V; Garber, A; Garcia, EM; García-Campos, C; García-Donas, J; García-Pérez, AL; Gasparri, F; Ge, C; Ge, D; Ge, JB; Ge, X; George, I; George, LA; Germani, G; Ghassemi Tabrizi, S; Gibon, Y; Gillent, E; Gillies, RS; Gilmour, MI; Goble, S; Goh, JC; Goiri, F; Goldfinger, LE; Golian, M; Gómez, MA; Gonçalves, J; Góngora-García, OR; Gonul, I; González, MA; Govers, TM; Grant, PC; Gray, EH; Gray, JE; Green, MS; Greenwald, I; Gregory, MJ; Gretzke, D; Griffin-Nolan, RJ; Griffith, DC; Gruppen, EG; Guaita, A; Guan, P; Guan, X; Guerci, P; Guerrero, DT; Guo, M; Guo, P; Guo, R; Guo, X; Gupta, J; Guz, G; Hajizadeh, N; Hamada, H; Haman-Wabi, AB; Han, TT; Hannan, N; Hao, S; Harjola, VP; Harmon, M; Hartmann, MSM; Hartwig, JF; Hasani, M; Hawthorne, WJ; Haykal-Coates, N; Hazari, MS; He, DL; He, P; He, SG; Héau, C; Hebbar Kannur, K; Helvaci, O; Heuberger, DM; Hidalgo, F; Hilty, MP; Hirata, K; Hirsch, A; Hoffman, AM; Hoffmann, JF; Holloway, RW; Holmes, RK; Hong, S; Hongisto, M; Hopf, NB; Hörlein, R; Hoshino, N; Hou, Y; Hoven, NF; Hsieh, YY; Hsu, CT; Hu, CW; Hu, JH; Hu, MY; Hu, Y; Hu, Z; Huang, C; Huang, D; Huang, DQ; Huang, L; Huang, Q; Huang, R; Huang, S; Huang, SC; Huang, W; Huang, Y; Huffman, KM; Hung, CH; Hung, CT; Huurman, R; Hwang, SM; Hyun, S; Ibrahim, AM; Iddi-Faical, A; Immordino, P; Isla, MI; Jacquemond, V; Jacques, T; Jankowska, E; Jansen, JA; Jäntti, T; Jaque-Fernandez, F; Jarvis, GA; Jatt, LP; Jeon, JW; Jeong, SH; Jhunjhunwala, R; Ji, F; Jia, X; Jia, Y; Jian-Bo, Z; Jiang, GD; Jiang, L; Jiang, W; Jiang, WD; Jiang, Z; Jiménez-Hoyos, CA; Jin, S; Jobling, MG; John, CM; John, T; Johnson, CB; Jones, KI; Jones, WS; Joseph, OO; Ju, C; Judeinstein, P; Junges, A; Junnarkar, M; Jurkko, R; Kaleka, CC; Kamath, AV; Kang, X; Kantsadi, AL; Kapoor, M; Karim, Z; Kashuba, ADM; Kassa, E; Kasztura, M; Kataja, A; Katoh, T; Kaufman, JS; Kaupp, M; Kehinde, O; Kehrenberg, C; Kemper, N; Kerr, CW; Khan, AU; Khan, MF; Khan, ZUH; Khojasteh, SC; Kilburn, S; Kim, CG; Kim, DU; Kim, DY; Kim, HJ; Kim, J; Kim, OH; Kim, YH; King, C; Klein, A; Klingler, L; Knapp, AK; Ko, TK; Kodavanti, UP; Kolla, V; Kong, L; Kong, RY; Kong, X; Kore, S; Kortz, U; Korucu, B; Kovacs, A; Krahnert, I; Kraus, WE; Kuang, SY; Kuehn-Hajder, JE; Kurz, M; Kuśtrowski, P; Kwak, YD; Kyttaris, VC; Laga, SM; Laguerre, A; Laloo, A; Langaro, MC; Langham, MC; Lao, X; Larocca, MC; Lassus, J; Lattimer, TA; Lazar, S; Le, MH; Leal, DB; Leal, M; Leary, A; Ledermann, JA; Lee, JF; Lee, MV; Lee, NH; Leeds, CM; Leeds, JS; Lefrandt, JD; Leicht, AS; Leonard, M; Lev, S; Levy, K; Li, B; Li, C; Li, CM; Li, DH; Li, H; Li, J; Li, L; Li, LJ; Li, N; Li, P; Li, T; Li, X; Li, XH; Li, XQ; Li, XX; Li, Y; Li, Z; Li, ZY; Liao, YF; Lin, CC; Lin, MH; Lin, Y; Ling, Y; Links, TP; Lira-Romero, E; Liu, C; Liu, D; Liu, H; Liu, J; Liu, L; Liu, LP; Liu, M; Liu, T; Liu, W; Liu, X; Liu, XH; Liu, Y; Liuwantara, D; Ljumanovic, N; Lobo, L; Lokhande, K; Lopes, A; Lopes, RMRM; López-Gutiérrez, JC; López-Muñoz, MJ; López-Santamaría, M; Lorenzo, C; Lorusso, D; Losito, I; Lu, C; Lu, H; Lu, HZ; Lu, SH; Lu, SN; Lu, Y; Lu, ZY; Luboga, F; Luo, JJ; Luo, KL; Luo, Y; Lutomski, CA; Lv, W; M Piedade, MF; Ma, J; Ma, JQ; Ma, JX; Ma, N; Ma, P; Ma, S; Maciel, M; Madureira, M; Maganaris, C; Maginn, EJ; Mahnashi, MH; Maierhofer, M; Majetschak, M; Malla, TR; Maloney, L; Mann, DL; Mansuri, A; Marelli, E; Margulis, CJ; Marrella, A; Martin, BL; Martín-Francés, L; Martínez de Pinillos, M; Martínez-Navarro, EM; Martinez-Quintanilla Jimenez, D; Martínez-Velasco, A; Martínez-Villaseñor, L; Martinón-Torres, M; Martins, BA; Massongo, M; Mathew, AP; Mathews, D; Matsui, J; Matsumoto, KI; Mau, T; Maves, RC; Mayclin, SJ; Mayer, JM; Maynard, ND; Mayr, T; Mboowa, MG; McEvoy, MP; McIntyre, RC; McKay, JA; McPhail, MJW; McVeigh, AL; Mebazaa, A; Medici, V; Medina, DN; Mehmood, T; Mei-Li, C; Melku, M; Meloncelli, S; Mendes, GC; Mendoza-Velásquez, C; Mercadante, R; Mercado, MI; Merenda, MEZ; Meunier, J; Mi, SL; Michels, M; Mijatovic, V; Mikhailov, V; Milheiro, SA; Miller, DC; Ming, F; Mitsuishi, M; Miyashita, T; Mo, J; Mo, S; Modesto-Mata, M; Moeller, S; Monte, A; Monteiro, L; Montomoli, J; Moore, EE; Moore, HB; Moore, PK; Mor, MK; Moratalla-López, N; Moratilla Lapeña, L; Moreira, R; Moreno, MA; Mörk, AC; Morton, M; Mosier, JM; Mou, LH; Mougharbel, AS; Muccillo-Baisch, AL; Muñoz-Serrano, AJ; Mustafa, B; Nair, GM; Nakanishi, I; Nakanjako, D; Naraparaju, K; Nawani, N; Neffati, R; Neil, EC; Neilipovitz, D; Neira-Borrajo, I; Nelson, MT; Nery, PB; Nese, M; Nguyen, F; Nguyen, MH; Niazy, AA; Nicolaï, J; Nogueira, F; Norbäck, D; Novaretti, JV; O'Donnell, T; O'Dowd, A; O'Malley, DM; Oaknin, A; Ogata, K; Ohkubo, K; Ojha, M; Olaleye, MT; Olawande, B; Olomo, EJ; Ong, EWY; Ono, A; Onwumere, J; Ortiz Bibriesca, DM; Ou, X; Oza, AM; Ozturk, K; Özütemiz, C; Palacio-Pastrana, C; Palaparthi, A; Palevsky, PM; Pan, K; Pantanetti, S; Papachristou, DJ; Pariani, A; Parikh, CR; Parissis, J; Paroul, N; Parry, S; Patel, N; Patel, SM; Patel, VC; Pawar, S; Pefura-Yone, EW; Peixoto Andrade, BCO; Pelepenko, LE; Peña-Lora, D; Peng, S; Pérez-Moro, OS; Perez-Ortiz, AC; Perry, LM; Peter, CM; Phillips, NJ; Phillips, P; Pia Tek, J; Piner, LW; Pinto, EA; Pinto, SN; Piyachaturawat, P; Poka-Mayap, V; Polledri, E; Poloni, TE; Ponessa, G; Poole, ST; Post, AK; Potter, TM; Pressly, BB; Prouty, MG; Prudêncio, M; Pulkki, K; Pupier, C; Qian, H; Qian, ZP; Qiu, Y; Qu, G; Rahimi, S; Rahman, AU; Ramadan, H; Ramanna, S; Ramirez, I; Randolph, GJ; Rasheed, A; Rault, J; Raviprakash, V; Reale, E; Redpath, C; Rema, V; Remucal, CK; Remy, D; Ren, T; Ribeiro, LB; Riboli, G; Richards, J; Rieger, V; Rieusset, J; Riva, A; Rivabella Maknis, T; Robbins, JL; Robinson, CV; Roche-Campo, F; Rodriguez, R; Rodríguez-de-Cía, J; Rollenhagen, JE; Rosen, EP; Rub, D; Rubin, N; Rubin, NT; Ruurda, JP; Saad, O; Sabell, T; Saber, SE; Sabet, M; Sadek, MM; Saejio, A; Salinas, RM; Saliu, IO; Sande, D; Sang, D; Sangenito, LS; Santos, ALSD; Sarmiento Caldas, MC; Sassaroli, S; Sassi, V; Sato, J; Sauaia, A; Saunders, K; Saunders, PR; Savarino, SJ; Scambia, G; Scanlon, N; Schetinger, MR; Schinkel, AFL; Schladweiler, MC; Schofield, CJ; Schuepbach, RA; Schulz, J; Schwartz, N; Scorcella, C; Seeley, J; Seemann, F; Seinige, D; Sengoku, T; Seravalli, J; Sgromo, B; Shaheen, MY; Shan, L; Shanmugam, S; Shao, H; Sharma, S; Shaw, KJ; Shen, BQ; Shen, CH; Shen, P; Shen, S; Shen, Y; Shen, Z; Shi, J; Shi-Li, L; Shimoda, K; Shoji, Y; Shun, C; Silva, MA; Silva-Cardoso, J; Simas, NK; Simirgiotis, MJ; Sincock, SA; Singh, MP; Sionis, A; Siu, J; Sivieri, EM; Sjerps, MJ; Skoczen, SL; Slabon, A; Slette, IJ; Smith, MD; Smith, S; Smith, TG; Snapp, KS; Snow, SJ; Soares, MCF; Soberman, D; Solares, MD; Soliman, I; Song, J; Sorooshian, A; Sorrell, TC; Spinar, J; Staudt, A; Steinhart, C; Stern, ST; Stevens, DM; Stiers, KM; Stimming, U; Su, YG; Subbian, V; Suga, H; Sukhija-Cohen, A; Suksamrarn, A; Suksen, K; Sun, J; Sun, M; Sun, P; Sun, W; Sun, XF; Sun, Y; Sundell, J; Susan, LF; Sutjarit, N; Swamy, KV; Swisher, EM; Sykes, C; Takahashi, JA; Talmor, DS; Tan, B; Tan, ZK; Tang, L; Tang, S; Tanner, JJ; Tanwar, M; Tarazi, Z; Tarvasmäki, T; Tay, FR; Teketel, A; Temitayo, GI; Thersleff, T; Thiessen Philbrook, H; Thompson, LC; Thongon, N; Tian, B; Tian, F; Tian, Q; Timothy, AT; Tingle, MD; Titze, IR; Tolppanen, H; Tong, W; Toyoda, H; Tronconi, L; Tseng, CH; Tu, H; Tu, YJ; Tung, SY; Turpault, S; Tuynman, JB; Uemoto, AT; Ugurlu, M; Ullah, S; Underwood, RS; Ungell, AL; Usandizaga-Elio, I; Vakonakis, I; van Boxel, GI; van den Beucken, JJJP; van der Boom, T; van Slegtenhorst, MA; Vanni, JR; Vaquera, A; Vasconcellos, RS; Velayos, M; Vena, R; Ventura, G; Verso, MG; Vincent, RP; Vitale, F; Vitali, S; Vlek, SL; Vleugels, MPH; Volkmann, N; Vukelic, M; Wagner Mackenzie, B; Wairagala, P; Waller, SB; Wan, J; Wan, MT; Wan, Y; Wang, CC; Wang, H; Wang, J; Wang, JF; Wang, K; Wang, L; Wang, M; Wang, S; Wang, WM; Wang, X; Wang, Y; Wang, YD; Wang, YF; Wang, Z; Wang, ZG; Warriner, K; Weberpals, JI; Weerachayaphorn, J; Wehrli, FW; Wei, J; Wei, KL; Weinheimer, CJ; Weisbord, SD; Wen, S; Wendel Garcia, PD; Williams, JW; Williams, R; Winkler, C; Wirman, AP; Wong, S; Woods, CM; Wu, B; Wu, C; Wu, F; Wu, P; Wu, S; Wu, Y; Wu, YN; Wu, ZH; Wurtzel, JGT; Xia, L; Xia, Z; Xia, ZZ; Xiao, H; Xie, C; Xin, ZM; Xing, Y; Xing, Z; Xu, S; Xu, SB; Xu, T; Xu, X; Xu, Y; Xue, L; Xun, J; Yaffe, MB; Yalew, A; Yamamoto, S; Yan, D; Yan, H; Yan, S; Yan, X; Yang, AD; Yang, E; Yang, H; Yang, J; Yang, JL; Yang, K; Yang, M; Yang, P; Yang, Q; Yang, S; Yang, W; Yang, X; Yang, Y; Yao, JC; Yao, WL; Yao, Y; Yaqub, TB; Ye, J; Ye, W; Yen, CW; Yeter, HH; Yin, C; Yip, V; Yong-Yi, J; Yu, HJ; Yu, MF; Yu, S; Yu, W; Yu, WW; Yu, X; Yuan, P; Yuan, Q; Yue, XY; Zaia, AA; Zakhary, SY; Zalwango, F; Zamalloa, A; Zamparo, P; Zampini, IC; Zani, JL; Zeitoun, R; Zeng, N; Zenteno, JC; Zepeda-Palacio, C; Zhai, C; Zhang, B; Zhang, G; Zhang, J; Zhang, K; Zhang, Q; Zhang, R; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, B; Zhao, D; Zhao, G; Zhao, H; Zhao, Q; Zhao, R; Zhao, S; Zhao, T; Zhao, X; Zhao, XA; Zhao, Y; Zhao, Z; Zheng, Z; Zhi-Min, G; Zhou, CL; Zhou, HD; Zhou, J; Zhou, W; Zhou, XQ; Zhou, Z; Zhu, C; Zhu, H; Zhu, L; Zhu, Y; Zitzmann, N; Zou, L; Zou, Y1
Ahirwar, DK; Charan, M; Chatterjee, N; Das, S; Ganju, RK; Kaul, K; Mishra, S; Misri, S; Satoskar, AR; Varikuti, S1
Chen, G; Ding, B; Duan, K; Li, X; Li, Y; Ouyang, W; Zhou, L1
Lee, TY; Liao, JF; Liu, HM1
Attri, SV; Kumar, B; Medhi, B; Modi, M; Patial, A; Saikia, B1
Bhatti, R; Gupta, M; Kumar, A; Sharma, A; Singh Ishar, MP; Singh, G1
Alzarea, S; Rahman, S2
Bhattacharya, P; Borah, A; Chakrabarty, J; Dutta, A; Mazumder, MK; Paul, R; Phukan, BC1
Batteux, F; Bordenave, J; Cumont, A; Dinh-Xuan, AT; Guignabert, C; Guilbert, T; Günther, S; Hua-Huy, T; Humbert, M; Jalce, G; Nicco, C; Quatremarre, T; Savale, L; Thuillet, R; Tu, L1
Hong, YP; Li, M; Mei, FC; Wang, WX; Yu, J; Zhao, L; Zhou, Y; Zuo, T1
Chen, J; Cong, X; Zhan, X; Zheng, W; Zhou, Z1
Wang, S; Wu, H; Wu, Y; Zhu, Y1
Duan, JA; Li, NG; Tang, YP1
Gu, Y; Jin, B; Liu, W; Luo, Q; Qian, C; Shen, Y; Sun, Y; Tao, F; Wu, X; Xu, Q1
Christoforidis, JB; Jiang, A; Joshi, M; Wang, J1
Georas, SN; Knowlden, S1
Aghdasi, BG; Cun, Y; Huang, B; Xiong, C; Zhou, Y1
Ding, Y; Shen, Q; Wild, C; Ye, N; Zhou, J1
Annaert, P; Darville, N; De Meulder, M; Sterkens, P; Van den Mooter, G; van Heerden, M; Vynckier, A1
Eckel, J; Görgens, SW; Peiró, C; Romacho, T; Sánchez-Ferrer, CF; Sell, H; Villalobos, LA; Wronkowitz, N1
Ben Jannet, H; Bouajila, J; Bousejra-El Garah, F; Filali, I; Znati, M1
Choe, JY; Kim, SK1
Dejaco, C; Duftner, C; Ficjan, A; Graninger, WB; Gretler, J; Gutierrez, M; Hermann, J; Husic, R; Lackner, A1
Cui, W; Yu, X; Zhang, H1
Boehm, GW; Chumley, MJ; Eimerbrink, MJ; Hodges, SL; Pendry, RJ; Sadler, LN; Weintraub, MK; White, JD; Wiles, JD1
Balaji, KS; Jagadish, S; Jayarama, S; Mohan, CD; Rakesh, KS; Rangappa, KS; Swaroop, TR; Zameer, F1
Chen, G; Li, X; Li, Y; Liang, H; Ouyang, W; Tong, J; Wu, Y; Zhou, L1
Deng, F; Feng, J; Wang, L; Zhang, P1
Cheng, E; Huo, X; Park, JY; Souza, RF; Spechler, SJ; Wang, DH; Wilson, KS; Yu, C; Zhang, Q; Zhang, X1
Bai, Y; Chen, B; Hong, W; Liang, Y; Lu, H; Wu, L1
Artym, J; Kochanowska, I; Kocięba, M; Mączyński, M; Ryng, S; Zimecki, M1
Li, P; Liu, Z; Yang, M; Yang, X1
Akbarali, HI; AlSharari, SD; Bagdas, D; Cabral, GA; Carroll, FI; Damaj, MI; Lichtman, PA; McGee, EA; Raborn, ES1
Brack, A; Broscheit, JA; Rittner, HL; Roewer, N; Sauer, RS; Shityakov, S; Sohajda, T1
Cai, J; Chen, RX; Liao, FF; Liu, FY; Wan, Y; Wang, J; Xu, FQ; Yi, M; Zhang, C; Zhang, Y1
Cho, ML; Jhun, JY; Kim, EK; Lee, HJ; Lee, WS; Min, JK; Moon, SJ; Park, SH1
Murakami, T; Ono, H; Tanabe, M1
Ahring, PK; Erichsen, HK; Larsen, JS; Lopez-Garcia, JA; Mirza, NR; Munro, G; Nielsen, EØ; Rivera-Arconada, I1
Herschman, HR; Ishikawa, TO; Jain, NK; Spigelman, I1
Avila, R; Cardenas, R; Quintero, L; Siso, A; Suarez-Roca, H; Urdaneta, A; Urdaneta, B1
Bosselmann, S; Chada, M; Gessner, A; Kandler, M; Nögel, SC; Rascher, W; Schmidt, AM; Schneider, H; Schweer, H; Watzer, B1
Gao, YW; Hou, XQ; Ma, ZY; Wang, CY; Xia, XZ; Yang, ST1
Guo, X; Liu, Y; Peng, Y; Shen, X; Wang, F; Xu, S; Yang, J1
Mateos, JL1
Bonassi, S; Cutolo, M; Gallo, F; Montagna, P; Moretti, S; Paolino, S; Pizzorni, C; Seriolo, B; Soldano, S; Sulli, A; Villaggio, B1
Choo, H; Chung, HJ; Kim, HJ; Koh, HY; Lee, JE; Lee, MJ; Lee, SC; Pae, AN; Shin, TJ1
Gupta, A; Kulkarni, SK; Kumar, A1
Leban, J; Vitt, D1
Glamoclija, J; Kataranovski, M; Mirkov, I; Stojanovic, I; Stosic-Grujicic, S1
Barry, GD; Cotterell, AJ; Fairlie, DP; Halili, MA; Le, GT; Lohman, RJ; Suen, JY1
Berdyshev, E; Chun, J; He, D; Natarajan, V; Su, Y; Zhao, J; Zhao, Y1
Liu, JP; Ren, XJ; Wang, H; Wang, JY; Yu, WM1
He, XH; Li, H; Song, XM; Wang, YL; Zhan, J; Zhang, ZZ1
Bamborough, P; Beinke, S; Bouillot, A; Chung, CW; Cutler, L; Donche, F; Gellibert, F; Gordon, L; Kirilovsky, J; Krysa, G; Lamotte, Y; Lee, K; Lewis, T; Lugo, D; McCleary, S; Mirguet, O; Nicodeme, E; Prinjha, RK; Rioja, I; Seal, J; Walker, AL; Wilson, DM; Witherington, J1
Christensen, J; Erichsen, H; Hansen, H; Hansen, R; Munro, G; Timmermann, D1
Baldelli, F; Cipriani, S; D'Amore, C; Fiorucci, S; Francisci, D; Mencarelli, A; Renga, B; Schiaroli, E1
Ahn, YM; Jung, HY; Kim, CE; Kim, WH; Kim, YS; Min, KJ; Na, KS; Park, KC; Ryu, SG; Yoon, JS1
Dong, N; Gui, P; Purusram, G; Wang, H; Wu, Q; Xie, W; Yao, S; Yuan, R1
Freitas, K; Ghosh, S; Imad Damaj, M; Ivy Carroll, F; Lichtman, AH1
Baban, B; Liu, JY; Mozaffari, MS1
Chiu, HF; Huang, WH; Lee, AR; Yang, CL1
Bevan, S; Courade, JP; Dawson, J; Fox, A; Glatt, M; Gonzalez, I; Medhurst, S; Urban, L1
Gierse, JK; Hood, WF; Isakson, PC; Koboldt, CM; Masferrer, JL; Maziasz, TJ; Muhammad, JL; Seibert, K; Trigg, JS; Walker, MC; Zhang, Y; Zweifel, BS1
Magari, K; Miyata, S; Mutoh, S; Nishigaki, F; Ohkubo, Y1
Beneytout, JL; Bertin, P; Léger, DY; Liagre, B; Trèves, R; Vergne-Salle, P1
Baldini, PM; Carotenuto, F; Chiurchiu', V; D'Aquilio, F; Di Nardo, P; Giambra, V; Izzi, V; Procaccini, M1
Chakradhar, LV; Naik, SR1
Bishop-Bailey, D; Li, YT; Swales, KE; Thomas, GJ; Warner, TD1
Czugler, M; Erdélyi, P; Fischer, J; Fodor, T; Gere, A; Varga, AK1
Berkenkoph, J; Fernandez, X; Friary, R; Green, MJ; Lutsky, BN; Monahan, M; Tiberi, RL1
Anagnostopulos, H; Bartlett, RR; Mattar, T; Schleyerbach, R; Zielinski, T1
Cannon, A; DeManvelle, T; Gregory, CR; Harb, M; Morris, RE; Ortega, T; Stewart, A; Sturges, B1
Andresen, C; Beckius, G; Chupak, L; Duplantier, A; Klein, A; Kraus, K; Kudlacz, E; Milici, A; Whitney, C1
Gister, S; Ludwig, BJ; Meyer, M; Powell, LS; Reisner, DB; Sofia, RD; Stiefel, FJ1
DiPasquale, G; Gingold, J; Rassaert, C; Richter, R; Singer, R; Welaj, P1
Hirschelmann, R; Schade, R1

Reviews

7 review(s) available for isoxazoles and Innate Inflammatory Response

ArticleYear
Intravenous parecoxib for early postoperative cognitive dysfunction in elderly patients: evidence from a meta-analysis.
    Expert review of clinical pharmacology, 2020, Volume: 13, Issue:4

    Topics: Aged; Animals; Asian People; Cyclooxygenase 2 Inhibitors; Humans; Inflammation; Isoxazoles; Postoperative Cognitive Complications; Randomized Controlled Trials as Topic

2020
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; Acyclic Monoterpenes; Adenine Nucleotides; Adhesins, Escherichia coli; Adipocytes; Adipocytes, Brown; Adipogenesis; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adsorption; Adult; Aeromonas hydrophila; Africa; Aged; Aged, 80 and over; Agrobacterium tumefaciens; Air; Air Pollutants; Air Pollution; Air Pollution, Indoor; Algorithms; Alkaloids; Alkynes; Allosteric Regulation; Amines; Amino Acid Sequence; Amino Acids; Amino Acids, Branched-Chain; Aminoisobutyric Acids; Aminopyridines; Amyotrophic Lateral Sclerosis; Anaerobic Threshold; Angiography; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animal Distribution; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Ankle Joint; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Inflammatory Agents; Antibodies, Bacterial; Antifungal Agents; Antimalarials; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Antiretroviral Therapy, Highly Active; Antiviral Agents; Aotidae; Apelin; Apoptosis; Arabidopsis Proteins; Argentina; Arginine; Artemisinins; Arthritis, Experimental; Arthritis, Rheumatoid; Arthroscopy; Aspergillus; Aspergillus niger; Asteraceae; Asthma; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Auditory Cortex; Autoantibodies; Autophagy; Bacteria; Bacterial Infections; Bacterial Proteins; Bacterial Typing Techniques; Base Composition; Base Sequence; Basketball; Beclin-1; Benzhydryl Compounds; Benzimidazoles; Benzo(a)pyrene; Benzofurans; Benzoxazines; Bereavement; beta Catenin; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Betacoronavirus; Betaine; Binding Sites; Biofilms; Biological Assay; Biological Availability; Biological Evolution; Biomarkers; Biomechanical Phenomena; Biopolymers; Biopsy; Bismuth; Blood Glucose; Blood Platelets; Blood Pressure; Body Composition; Body Weight; Bone Marrow; Bone Marrow Cells; Bone Regeneration; Boron; Botrytis; Brain Ischemia; Brain Neoplasms; Brain-Derived Neurotrophic Factor; Brazil; Breast Neoplasms; Breath Tests; Bronchoalveolar Lavage Fluid; Burkholderia; C-Reactive Protein; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcification, Physiologic; Calcium; Calcium Signaling; Calorimetry, Differential Scanning; Cameroon; Camptothecin; Candida; Candida albicans; Capillaries; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Carbohydrate Conformation; Carbon; Carbon Dioxide; Carbon Isotopes; Carcinoma, Ovarian Epithelial; Cardiac Output; Cardiomyopathy, Hypertrophic; Cardiotonic Agents; Cardiovascular Diseases; Caregivers; Carps; Case-Control Studies; Catalase; Catalysis; Cats; CD4 Lymphocyte Count; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Cellulose; Centrosome; Ceratopogonidae; Chickens; Child; China; Cholera Toxin; Choline; Cholinesterases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Micellar Electrokinetic Capillary; Chromatography, Reverse-Phase; Chronic Disease; Cinnamates; Cities; Citrates; Climate Change; Clinical Trials, Phase III as Topic; Coal; Coal Mining; Cohort Studies; Coinfection; Colchicine; Colony Count, Microbial; Colorectal Neoplasms; Coloring Agents; Common Cold; Complement Factor H; Computational Biology; Computer Simulation; Continuous Positive Airway Pressure; Contrast Media; Coordination Complexes; Coronary Artery Bypass; Coronavirus 3C Proteases; Coronavirus Infections; Coronavirus Protease Inhibitors; Corynebacterium glutamicum; Cosmetics; COVID-19; Creatinine; Cross-Sectional Studies; Crotonates; Crystallography, X-Ray; Cues; Culicidae; Culture Media; Curcuma; Cyclopentanes; Cyclopropanes; Cymbopogon; Cystine; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Cytokines; Databases, Genetic; Death; Dendritic Cells; Density Functional Theory; Depsides; Diabetes Mellitus, Type 2; Diamond; Diarylheptanoids; Dibenzofurans; Dibenzofurans, Polychlorinated; Diclofenac; Diet; Dietary Carbohydrates; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Dioxins; Diphenylamine; Disease Outbreaks; Disease Susceptibility; Disulfides; Dithiothreitol; Dizocilpine Maleate; DNA Methylation; DNA-Binding Proteins; DNA, Bacterial; Dogs; Dose-Response Relationship, Drug; Double-Blind Method; Doublecortin Protein; Drosophila melanogaster; Droughts; Drug Carriers; Drug Combinations; Drug Delivery Systems; Drug Liberation; Drug Resistance; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Dust; Dynactin Complex; Dysferlin; Echo-Planar Imaging; Echocardiography; Edaravone; Egypt; Elasticity; Electrodes; Electrolytes; Emodin; Emtricitabine; Endometriosis; Endothelium, Vascular; Endotoxins; Energy Metabolism; Energy Transfer; Enterobacteriaceae; Enterococcus faecalis; Enterotoxigenic Escherichia coli; Environmental Monitoring; Enzyme Inhibitors; Epidemiologic Factors; Epigenesis, Genetic; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Vaccines; Esophageal Neoplasms; Esophagectomy; Esophagogastric Junction; Esterases; Esterification; Ethanol; Ethiopia; Ethnicity; Eucalyptus; Evidence-Based Practice; Exercise; Exercise Tolerance; Extracorporeal Membrane Oxygenation; Family; Fatty Acids; Feedback; Female; Ferric Compounds; Fibrin Fibrinogen Degradation Products; Filtration; Fish Diseases; Flavonoids; Flavonols; Fluorodeoxyglucose F18; Follow-Up Studies; Food Microbiology; Food Preservation; Forests; Fossils; Free Radical Scavengers; Freund's Adjuvant; Fruit; Fungi; Gallium; Gender Identity; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Genes, Bacterial; Genes, Plant; Genetic Predisposition to Disease; Genitalia; Genotype; Glomerulonephritis, IGA; Glottis; Glucocorticoids; Glucose; Glucuronides; Glutathione Transferase; Glycogen Synthase Kinase 3 beta; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Grassland; Guinea Pigs; Half-Life; Head Kidney; Heart Atria; Heart Rate; Heart Septum; HEK293 Cells; Hematopoietic Stem Cells; Hemodynamics; Hep G2 Cells; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Hepatocytes; Hesperidin; High-Frequency Ventilation; High-Temperature Requirement A Serine Peptidase 1; Hippocampus; Hirudins; History, 20th Century; History, 21st Century; HIV Infections; Homeostasis; Hominidae; Housing, Animal; Humans; Hydrocarbons, Brominated; Hydrogen Bonding; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxybutyrates; Hydroxyl Radical; Hypertension; Hypothyroidism; Image Interpretation, Computer-Assisted; Immunoconjugates; Immunogenic Cell Death; Indoles; Infant, Newborn; Infant, Premature; Infarction, Middle Cerebral Artery; Inflammation; Inflammation Mediators; Infrared Rays; Inhibitory Concentration 50; Injections, Intravenous; Interferon-gamma; Interleukin-23; Interleukin-4; Interleukin-6; Intermediate Filaments; Intermittent Claudication; Intestine, Small; Iridoid Glucosides; Iridoids; Iron; Isomerism; Isotope Labeling; Isoxazoles; Itraconazole; Kelch-Like ECH-Associated Protein 1; Ketoprofen; Kidney Failure, Chronic; Kinetics; Klebsiella pneumoniae; Lactams, Macrocyclic; Lactobacillus; Lactulose; Lakes; Lamivudine; Laparoscopy; Laparotomy; Laryngoscopy; Leucine; Limit of Detection; Linear Models; Lipid A; Lipopolysaccharides; Listeria monocytogenes; Liver; Liver Cirrhosis; Logistic Models; Longitudinal Studies; Losartan; Low Back Pain; Lung; Lupinus; Lupus Erythematosus, Systemic; Machine Learning; Macular Degeneration; Madin Darby Canine Kidney Cells; Magnetic Phenomena; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetics; Malaria, Falciparum; Male; Mannans; MAP Kinase Signaling System; Mass Spectrometry; Melatonin; Membrane Glycoproteins; Membrane Proteins; Meniscectomy; Menisci, Tibial; Mephenytoin; Mesenchymal Stem Cells; Metal Nanoparticles; Metal-Organic Frameworks; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mice, Obese; Mice, Transgenic; Microbial Sensitivity Tests; Microcirculation; MicroRNAs; Microscopy, Video; Microtubules; Microvascular Density; Microwaves; Middle Aged; Minimally Invasive Surgical Procedures; Models, Animal; Models, Biological; Models, Molecular; Models, Theoretical; Molecular Docking Simulation; Molecular Structure; Molecular Weight; Morus; Mouth Floor; Multicenter Studies as Topic; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Muscle, Skeletal; Myocardial Ischemia; Myocardium; NAD; NADP; Nanocomposites; Nanoparticles; Naphthols; Nasal Lavage Fluid; Nasal Mucosa; Neisseria meningitidis; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasms, Experimental; Neural Stem Cells; Neuroblastoma; Neurofilament Proteins; Neurogenesis; Neurons; New York; NF-E2-Related Factor 2; NF-kappa B; Nicotine; Nitriles; Nitrogen; Nitrogen Fixation; North America; Observer Variation; Occupational Exposure; Ochrobactrum; Oils, Volatile; Olea; Oligosaccharides; Omeprazole; Open Field Test; Optimism; Oregon; Oryzias; Osmolar Concentration; Osteoarthritis; Osteoblasts; Osteogenesis; Ovarian Neoplasms; Ovariectomy; Oxadiazoles; Oxidation-Reduction; Oxidative Stress; Oxygen; Ozone; p38 Mitogen-Activated Protein Kinases; Pakistan; Pandemics; Particle Size; Particulate Matter; Patient-Centered Care; Pelargonium; Peptides; Perception; Peripheral Arterial Disease; Peroxides; Pets; Pharmaceutical Preparations; Pharmacogenetics; Phenobarbital; Phenols; Phenotype; Phosphates; Phosphatidylethanolamines; Phosphines; Phospholipids; Phosphorus; Phosphorylation; Photoacoustic Techniques; Photochemotherapy; Photosensitizing Agents; Phylogeny; Phytoestrogens; Pilot Projects; Plant Components, Aerial; Plant Extracts; Plant Immunity; Plant Leaves; Plant Oils; Plants, Medicinal; Plasmodium berghei; Plasmodium falciparum; Platelet Activation; Platelet Function Tests; Pneumonia, Viral; Poaceae; Pogostemon; Poloxamer; Poly I; Poly(ADP-ribose) Polymerase Inhibitors; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Polyethylene Glycols; Polylysine; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Population Dynamics; Portasystemic Shunt, Transjugular Intrahepatic; Positron Emission Tomography Computed Tomography; Postoperative Complications; Postprandial Period; Potassium Cyanide; Predictive Value of Tests; Prefrontal Cortex; Pregnancy; Prepulse Inhibition; Prevalence; Procalcitonin; Prodrugs; Prognosis; Progression-Free Survival; Proline; Proof of Concept Study; Prospective Studies; Protein Binding; Protein Conformation; Protein Domains; Protein Folding; Protein Multimerization; Protein Sorting Signals; Protein Structure, Secondary; Proton Pump Inhibitors; Protozoan Proteins; Psychometrics; Pulse Wave Analysis; Pyridines; Pyrrolidines; Quality of Life; Quantum Dots; Quinoxalines; Quorum Sensing; Radiopharmaceuticals; Rain; Random Allocation; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Rats, Wistar; RAW 264.7 Cells; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, PAR-1; Receptors, CXCR4; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Interleukin-1; Receptors, Interleukin-17; Receptors, Notch; Recombinant Fusion Proteins; Recombinant Proteins; Reducing Agents; Reflex, Startle; Regional Blood Flow; Regression Analysis; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Tract Diseases; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Risk Assessment; Risk Factors; Rituximab; RNA, Messenger; RNA, Ribosomal, 16S; ROC Curve; Rosmarinic Acid; Running; Ruthenium; Rutin; Sarcolemma; Sarcoma; Sarcopenia; Sarcoplasmic Reticulum; SARS-CoV-2; Scavenger Receptors, Class A; Schools; Seasons; Seeds; Sequence Analysis, DNA; Severity of Illness Index; Sex Factors; Shock, Cardiogenic; Short Chain Dehydrogenase-Reductases; Signal Transduction; Silver; Singlet Oxygen; Sinusitis; Skin; Skin Absorption; Small Molecule Libraries; Smoke; Socioeconomic Factors; Soil; Soil Microbiology; Solid Phase Extraction; Solubility; Solvents; Spain; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Speech; Speech Perception; Spindle Poles; Spleen; Sporothrix; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Stomach Neoplasms; Stress, Physiological; Stroke Volume; Structure-Activity Relationship; Substrate Specificity; Sulfonamides; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Rate; T-Lymphocytes, Cytotoxic; Tandem Mass Spectrometry; Temperature; Tenofovir; Terpenes; Tetracycline; Tetrapleura; Textiles; Thermodynamics; Thiobarbituric Acid Reactive Substances; Thrombin; Thyroid Hormones; Thyroid Neoplasms; Tibial Meniscus Injuries; Time Factors; Tissue Distribution; Titanium; Toluidines; Tomography, X-Ray Computed; Tooth; Tramadol; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transgender Persons; Translations; Treatment Outcome; Triglycerides; Ubiquinone; Ubiquitin-Specific Proteases; United Kingdom; United States; Up-Regulation; Vascular Stiffness; Veins; Ventricular Remodeling; Viral Load; Virulence Factors; Virus Replication; Vitis; Voice; Voice Quality; Wastewater; Water; Water Pollutants, Chemical; Water-Electrolyte Balance; Weather; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Young Adult; Zoogloea

2022
Systemic treatments for noninfectious vitreous inflammation.
    Mediators of inflammation, 2013, Volume: 2013

    Topics: Adalimumab; Adrenal Cortex Hormones; Antibodies, Monoclonal, Humanized; Eye Diseases; Humans; Immunosuppressive Agents; Inflammation; Isoxazoles; Leflunomide; Vitreous Body

2013
The autotaxin-LPA axis emerges as a novel regulator of lymphocyte homing and inflammation.
    Journal of immunology (Baltimore, Md. : 1950), 2014, Feb-01, Volume: 192, Issue:3

    Topics: Adaptive Immunity; Airway Remodeling; Animals; Antigens; Asthma; Cell Movement; Chemotaxis, Leukocyte; Dendritic Cells; Humans; Inflammation; Isoxazoles; Lymphoid Tissue; Lysophospholipids; Mice; Phosphoric Diester Hydrolases; Propionates; Radiation Chimera; Receptors, Lysophosphatidic Acid; Signal Transduction; T-Lymphocytes; Up-Regulation; Venules

2014
[Selective inhibitors of cyclooxygenase-2 (COX-2), celecoxib and parecoxib: a systematic review].
    Drugs of today (Barcelona, Spain : 1998), 2010, Volume: 46 Suppl A

    Topics: Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Administration Routes; Evidence-Based Medicine; Humans; Inflammation; Isoxazoles; Pain; Pain Measurement; Pyrazoles; Structure-Activity Relationship; Sulfonamides; Treatment Outcome

2010
Human dihydroorotate dehydrogenase inhibitors, a novel approach for the treatment of autoimmune and inflammatory diseases.
    Arzneimittel-Forschung, 2011, Volume: 61, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Autoimmune Diseases; Dihydroorotate Dehydrogenase; Drug Design; Enzyme Inhibitors; Humans; Inflammation; Isoxazoles; Leflunomide; Oxidoreductases Acting on CH-CH Group Donors; Randomized Controlled Trials as Topic; Structure-Activity Relationship

2011
Effects of leflunomide on immune responses and models of inflammation.
    Springer seminars in immunopathology, 1993, Volume: 14, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Autoimmune Diseases; Cytokines; Disease Models, Animal; Drug Evaluation, Preclinical; Graft Rejection; Humans; Immunity, Cellular; Immunosuppressive Agents; Inflammation; Isoxazoles; Leflunomide; Mice; Protein-Tyrosine Kinases; Rats

1993

Trials

5 trial(s) available for isoxazoles and Innate Inflammatory Response

ArticleYear
    Zeitschrift fur Gesundheitswissenschaften = Journal of public health, 2022, Volume: 30, Issue:2

    Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; Acyclic Monoterpenes; Adenine Nucleotides; Adhesins, Escherichia coli; Adipocytes; Adipocytes, Brown; Adipogenesis; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adsorption; Adult; Aeromonas hydrophila; Africa; Aged; Aged, 80 and over; Agrobacterium tumefaciens; Air; Air Pollutants; Air Pollution; Air Pollution, Indoor; Algorithms; Alkaloids; Alkynes; Allosteric Regulation; Amines; Amino Acid Sequence; Amino Acids; Amino Acids, Branched-Chain; Aminoisobutyric Acids; Aminopyridines; Amyotrophic Lateral Sclerosis; Anaerobic Threshold; Angiography; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animal Distribution; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Ankle Joint; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Inflammatory Agents; Antibodies, Bacterial; Antifungal Agents; Antimalarials; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Antiretroviral Therapy, Highly Active; Antiviral Agents; Aotidae; Apelin; Apoptosis; Arabidopsis Proteins; Argentina; Arginine; Artemisinins; Arthritis, Experimental; Arthritis, Rheumatoid; Arthroscopy; Aspergillus; Aspergillus niger; Asteraceae; Asthma; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Auditory Cortex; Autoantibodies; Autophagy; Bacteria; Bacterial Infections; Bacterial Proteins; Bacterial Typing Techniques; Base Composition; Base Sequence; Basketball; Beclin-1; Benzhydryl Compounds; Benzimidazoles; Benzo(a)pyrene; Benzofurans; Benzoxazines; Bereavement; beta Catenin; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Betacoronavirus; Betaine; Binding Sites; Biofilms; Biological Assay; Biological Availability; Biological Evolution; Biomarkers; Biomechanical Phenomena; Biopolymers; Biopsy; Bismuth; Blood Glucose; Blood Platelets; Blood Pressure; Body Composition; Body Weight; Bone Marrow; Bone Marrow Cells; Bone Regeneration; Boron; Botrytis; Brain Ischemia; Brain Neoplasms; Brain-Derived Neurotrophic Factor; Brazil; Breast Neoplasms; Breath Tests; Bronchoalveolar Lavage Fluid; Burkholderia; C-Reactive Protein; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcification, Physiologic; Calcium; Calcium Signaling; Calorimetry, Differential Scanning; Cameroon; Camptothecin; Candida; Candida albicans; Capillaries; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Carbohydrate Conformation; Carbon; Carbon Dioxide; Carbon Isotopes; Carcinoma, Ovarian Epithelial; Cardiac Output; Cardiomyopathy, Hypertrophic; Cardiotonic Agents; Cardiovascular Diseases; Caregivers; Carps; Case-Control Studies; Catalase; Catalysis; Cats; CD4 Lymphocyte Count; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Cellulose; Centrosome; Ceratopogonidae; Chickens; Child; China; Cholera Toxin; Choline; Cholinesterases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Micellar Electrokinetic Capillary; Chromatography, Reverse-Phase; Chronic Disease; Cinnamates; Cities; Citrates; Climate Change; Clinical Trials, Phase III as Topic; Coal; Coal Mining; Cohort Studies; Coinfection; Colchicine; Colony Count, Microbial; Colorectal Neoplasms; Coloring Agents; Common Cold; Complement Factor H; Computational Biology; Computer Simulation; Continuous Positive Airway Pressure; Contrast Media; Coordination Complexes; Coronary Artery Bypass; Coronavirus 3C Proteases; Coronavirus Infections; Coronavirus Protease Inhibitors; Corynebacterium glutamicum; Cosmetics; COVID-19; Creatinine; Cross-Sectional Studies; Crotonates; Crystallography, X-Ray; Cues; Culicidae; Culture Media; Curcuma; Cyclopentanes; Cyclopropanes; Cymbopogon; Cystine; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Cytokines; Databases, Genetic; Death; Dendritic Cells; Density Functional Theory; Depsides; Diabetes Mellitus, Type 2; Diamond; Diarylheptanoids; Dibenzofurans; Dibenzofurans, Polychlorinated; Diclofenac; Diet; Dietary Carbohydrates; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Dioxins; Diphenylamine; Disease Outbreaks; Disease Susceptibility; Disulfides; Dithiothreitol; Dizocilpine Maleate; DNA Methylation; DNA-Binding Proteins; DNA, Bacterial; Dogs; Dose-Response Relationship, Drug; Double-Blind Method; Doublecortin Protein; Drosophila melanogaster; Droughts; Drug Carriers; Drug Combinations; Drug Delivery Systems; Drug Liberation; Drug Resistance; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Dust; Dynactin Complex; Dysferlin; Echo-Planar Imaging; Echocardiography; Edaravone; Egypt; Elasticity; Electrodes; Electrolytes; Emodin; Emtricitabine; Endometriosis; Endothelium, Vascular; Endotoxins; Energy Metabolism; Energy Transfer; Enterobacteriaceae; Enterococcus faecalis; Enterotoxigenic Escherichia coli; Environmental Monitoring; Enzyme Inhibitors; Epidemiologic Factors; Epigenesis, Genetic; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Vaccines; Esophageal Neoplasms; Esophagectomy; Esophagogastric Junction; Esterases; Esterification; Ethanol; Ethiopia; Ethnicity; Eucalyptus; Evidence-Based Practice; Exercise; Exercise Tolerance; Extracorporeal Membrane Oxygenation; Family; Fatty Acids; Feedback; Female; Ferric Compounds; Fibrin Fibrinogen Degradation Products; Filtration; Fish Diseases; Flavonoids; Flavonols; Fluorodeoxyglucose F18; Follow-Up Studies; Food Microbiology; Food Preservation; Forests; Fossils; Free Radical Scavengers; Freund's Adjuvant; Fruit; Fungi; Gallium; Gender Identity; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Genes, Bacterial; Genes, Plant; Genetic Predisposition to Disease; Genitalia; Genotype; Glomerulonephritis, IGA; Glottis; Glucocorticoids; Glucose; Glucuronides; Glutathione Transferase; Glycogen Synthase Kinase 3 beta; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Grassland; Guinea Pigs; Half-Life; Head Kidney; Heart Atria; Heart Rate; Heart Septum; HEK293 Cells; Hematopoietic Stem Cells; Hemodynamics; Hep G2 Cells; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Hepatocytes; Hesperidin; High-Frequency Ventilation; High-Temperature Requirement A Serine Peptidase 1; Hippocampus; Hirudins; History, 20th Century; History, 21st Century; HIV Infections; Homeostasis; Hominidae; Housing, Animal; Humans; Hydrocarbons, Brominated; Hydrogen Bonding; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxybutyrates; Hydroxyl Radical; Hypertension; Hypothyroidism; Image Interpretation, Computer-Assisted; Immunoconjugates; Immunogenic Cell Death; Indoles; Infant, Newborn; Infant, Premature; Infarction, Middle Cerebral Artery; Inflammation; Inflammation Mediators; Infrared Rays; Inhibitory Concentration 50; Injections, Intravenous; Interferon-gamma; Interleukin-23; Interleukin-4; Interleukin-6; Intermediate Filaments; Intermittent Claudication; Intestine, Small; Iridoid Glucosides; Iridoids; Iron; Isomerism; Isotope Labeling; Isoxazoles; Itraconazole; Kelch-Like ECH-Associated Protein 1; Ketoprofen; Kidney Failure, Chronic; Kinetics; Klebsiella pneumoniae; Lactams, Macrocyclic; Lactobacillus; Lactulose; Lakes; Lamivudine; Laparoscopy; Laparotomy; Laryngoscopy; Leucine; Limit of Detection; Linear Models; Lipid A; Lipopolysaccharides; Listeria monocytogenes; Liver; Liver Cirrhosis; Logistic Models; Longitudinal Studies; Losartan; Low Back Pain; Lung; Lupinus; Lupus Erythematosus, Systemic; Machine Learning; Macular Degeneration; Madin Darby Canine Kidney Cells; Magnetic Phenomena; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetics; Malaria, Falciparum; Male; Mannans; MAP Kinase Signaling System; Mass Spectrometry; Melatonin; Membrane Glycoproteins; Membrane Proteins; Meniscectomy; Menisci, Tibial; Mephenytoin; Mesenchymal Stem Cells; Metal Nanoparticles; Metal-Organic Frameworks; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mice, Obese; Mice, Transgenic; Microbial Sensitivity Tests; Microcirculation; MicroRNAs; Microscopy, Video; Microtubules; Microvascular Density; Microwaves; Middle Aged; Minimally Invasive Surgical Procedures; Models, Animal; Models, Biological; Models, Molecular; Models, Theoretical; Molecular Docking Simulation; Molecular Structure; Molecular Weight; Morus; Mouth Floor; Multicenter Studies as Topic; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Muscle, Skeletal; Myocardial Ischemia; Myocardium; NAD; NADP; Nanocomposites; Nanoparticles; Naphthols; Nasal Lavage Fluid; Nasal Mucosa; Neisseria meningitidis; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasms, Experimental; Neural Stem Cells; Neuroblastoma; Neurofilament Proteins; Neurogenesis; Neurons; New York; NF-E2-Related Factor 2; NF-kappa B; Nicotine; Nitriles; Nitrogen; Nitrogen Fixation; North America; Observer Variation; Occupational Exposure; Ochrobactrum; Oils, Volatile; Olea; Oligosaccharides; Omeprazole; Open Field Test; Optimism; Oregon; Oryzias; Osmolar Concentration; Osteoarthritis; Osteoblasts; Osteogenesis; Ovarian Neoplasms; Ovariectomy; Oxadiazoles; Oxidation-Reduction; Oxidative Stress; Oxygen; Ozone; p38 Mitogen-Activated Protein Kinases; Pakistan; Pandemics; Particle Size; Particulate Matter; Patient-Centered Care; Pelargonium; Peptides; Perception; Peripheral Arterial Disease; Peroxides; Pets; Pharmaceutical Preparations; Pharmacogenetics; Phenobarbital; Phenols; Phenotype; Phosphates; Phosphatidylethanolamines; Phosphines; Phospholipids; Phosphorus; Phosphorylation; Photoacoustic Techniques; Photochemotherapy; Photosensitizing Agents; Phylogeny; Phytoestrogens; Pilot Projects; Plant Components, Aerial; Plant Extracts; Plant Immunity; Plant Leaves; Plant Oils; Plants, Medicinal; Plasmodium berghei; Plasmodium falciparum; Platelet Activation; Platelet Function Tests; Pneumonia, Viral; Poaceae; Pogostemon; Poloxamer; Poly I; Poly(ADP-ribose) Polymerase Inhibitors; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Polyethylene Glycols; Polylysine; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Population Dynamics; Portasystemic Shunt, Transjugular Intrahepatic; Positron Emission Tomography Computed Tomography; Postoperative Complications; Postprandial Period; Potassium Cyanide; Predictive Value of Tests; Prefrontal Cortex; Pregnancy; Prepulse Inhibition; Prevalence; Procalcitonin; Prodrugs; Prognosis; Progression-Free Survival; Proline; Proof of Concept Study; Prospective Studies; Protein Binding; Protein Conformation; Protein Domains; Protein Folding; Protein Multimerization; Protein Sorting Signals; Protein Structure, Secondary; Proton Pump Inhibitors; Protozoan Proteins; Psychometrics; Pulse Wave Analysis; Pyridines; Pyrrolidines; Quality of Life; Quantum Dots; Quinoxalines; Quorum Sensing; Radiopharmaceuticals; Rain; Random Allocation; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Rats, Wistar; RAW 264.7 Cells; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, PAR-1; Receptors, CXCR4; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Interleukin-1; Receptors, Interleukin-17; Receptors, Notch; Recombinant Fusion Proteins; Recombinant Proteins; Reducing Agents; Reflex, Startle; Regional Blood Flow; Regression Analysis; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Tract Diseases; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Risk Assessment; Risk Factors; Rituximab; RNA, Messenger; RNA, Ribosomal, 16S; ROC Curve; Rosmarinic Acid; Running; Ruthenium; Rutin; Sarcolemma; Sarcoma; Sarcopenia; Sarcoplasmic Reticulum; SARS-CoV-2; Scavenger Receptors, Class A; Schools; Seasons; Seeds; Sequence Analysis, DNA; Severity of Illness Index; Sex Factors; Shock, Cardiogenic; Short Chain Dehydrogenase-Reductases; Signal Transduction; Silver; Singlet Oxygen; Sinusitis; Skin; Skin Absorption; Small Molecule Libraries; Smoke; Socioeconomic Factors; Soil; Soil Microbiology; Solid Phase Extraction; Solubility; Solvents; Spain; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Speech; Speech Perception; Spindle Poles; Spleen; Sporothrix; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Stomach Neoplasms; Stress, Physiological; Stroke Volume; Structure-Activity Relationship; Substrate Specificity; Sulfonamides; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Rate; T-Lymphocytes, Cytotoxic; Tandem Mass Spectrometry; Temperature; Tenofovir; Terpenes; Tetracycline; Tetrapleura; Textiles; Thermodynamics; Thiobarbituric Acid Reactive Substances; Thrombin; Thyroid Hormones; Thyroid Neoplasms; Tibial Meniscus Injuries; Time Factors; Tissue Distribution; Titanium; Toluidines; Tomography, X-Ray Computed; Tooth; Tramadol; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transgender Persons; Translations; Treatment Outcome; Triglycerides; Ubiquinone; Ubiquitin-Specific Proteases; United Kingdom; United States; Up-Regulation; Vascular Stiffness; Veins; Ventricular Remodeling; Viral Load; Virulence Factors; Virus Replication; Vitis; Voice; Voice Quality; Wastewater; Water; Water Pollutants, Chemical; Water-Electrolyte Balance; Weather; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Young Adult; Zoogloea

2022
[Parecoxib suppresses the increase of neutrophil-to-lymphocyte ratio after the modified radical mastectomy].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2017, Sep-28, Volume: 42, Issue:9

    Topics: Breast Neoplasms; Cyclooxygenase 2 Inhibitors; Female; Humans; Inflammation; Isoxazoles; Lymphocytes; Mastectomy; Neutrophils; Treatment Outcome

2017
Effect of perioperative parecoxib on postoperative pain and local inflammation factors PGE2 and IL-6 for total knee arthroplasty: a randomized, double-blind, placebo-controlled study.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2014, Volume: 24, Issue:3

    Topics: Aged; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Cyclooxygenase 2 Inhibitors; Dinoprostone; Double-Blind Method; Female; Humans; Inflammation; Interleukin-6; Isoxazoles; Knee Joint; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Postoperative Nausea and Vomiting; Range of Motion, Articular; Synovial Fluid

2014
Propranolol Attenuates Surgical Stress-Induced Elevation of the Regulatory T Cell Response in Patients Undergoing Radical Mastectomy.
    Journal of immunology (Baltimore, Md. : 1950), 2016, Apr-15, Volume: 196, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Breast Neoplasms; Catecholamines; Cell Proliferation; Cells, Cultured; Dinoprostone; Epinephrine; Female; Forkhead Transcription Factors; Humans; Immune Tolerance; Inflammation; Interferon-gamma; Isoxazoles; Leukocytes, Mononuclear; Lymphocyte Count; Mastectomy, Radical; Middle Aged; Norepinephrine; Propranolol; RNA, Messenger; Stress, Physiological; T-Lymphocytes, Regulatory

2016
The efficacy of parecoxib on systemic inflammatory response associated with cardiopulmonary bypass during cardiac surgery.
    British journal of clinical pharmacology, 2013, Volume: 75, Issue:3

    Topics: Adult; Biomarkers; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Creatine Kinase; Creatine Kinase, MB Form; Cyclooxygenase 2 Inhibitors; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Heart Valve Prosthesis Implantation; Humans; Inflammation; Isoxazoles; Leukocyte Count; Male; Middle Aged; Mitral Valve; Postoperative Complications; Treatment Outcome; Troponin T

2013

Other Studies

74 other study(ies) available for isoxazoles and Innate Inflammatory Response

ArticleYear
Protective effect of parecoxib sodium against ischemia reperfusion‑induced intestinal injury.
    Molecular medicine reports, 2021, Volume: 24, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cyclooxygenase 2 Inhibitors; Inflammation; Isoxazoles; Male; Malondialdehyde; Oxidative Stress; Peroxidase; Protective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction

2021
Parecoxib mitigates lung ischemia-reperfusion injury in rats by reducing oxidative stress and inflammation and up-regulating HO-1 expression.
    Acta cirurgica brasileira, 2021, Volume: 36, Issue:9

    Topics: Animals; Heme Oxygenase-1; Inflammation; Isoxazoles; Lung; Lung Injury; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2021
Parecoxib ameliorates renal toxicity and injury in sepsis-induced mouse model and LPS-induced HK-2 cells.
    Drug development research, 2022, Volume: 83, Issue:3

    Topics: Acute Kidney Injury; Animals; Apoptosis; Cyclooxygenase 2; Disease Models, Animal; I-kappa B Kinase; Inflammation; Isoxazoles; Lipopolysaccharides; Mice; NF-kappa B; Sepsis

2022
c-Fos is a mechanosensor that regulates inflammatory responses and lung barrier dysfunction during ventilator-induced acute lung injury.
    BMC pulmonary medicine, 2022, Jan-06, Volume: 22, Issue:1

    Topics: Animals; Apoptosis; Benzophenones; Inflammation; Isoxazoles; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Ventilator-Induced Lung Injury

2022
Activated clotting factor X mediates mitochondrial alterations and inflammatory responses via protease-activated receptor signaling in alveolar epithelial cells.
    European journal of pharmacology, 2020, Feb-15, Volume: 869

    Topics: Apoptosis; Cell Line, Tumor; Dipeptides; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Factor Xa; Factor Xa Inhibitors; Humans; Inflammation; Isoxazoles; Mitochondria; Pyridines; Receptors, Proteinase-Activated; Signal Transduction; Thiazoles

2020
A Facile One-Pot Synthesis of 3-Methylbenzisoxazoles
    Current organic synthesis, 2019, Volume: 16, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Coordination Complexes; Cyclization; Diclofenac; Disease Models, Animal; Drug Design; Inflammation; Isoxazoles; Ketones; Molecular Structure; Oxidation-Reduction; Rats; Structure-Activity Relationship; Tin Compounds

2019
Heat Shock Protein 27 Regulates the Inflammatory Response of Intestinal Epithelial Cells by the Nuclear Factor-κB Pathway.
    Digestive diseases and sciences, 2020, Volume: 65, Issue:12

    Topics: Anisoles; Antimetabolites; Cells, Cultured; Diarrhea; Gene Silencing; HSP27 Heat-Shock Proteins; Humans; Inflammation; Intestinal Mucosa; Irritable Bowel Syndrome; Isoxazoles; NF-kappa B; Phosphorylation; RNA, Small Interfering; Signal Transduction

2020
Macrophage migration inhibitory factor inhibition as a novel therapeutic approach against triple-negative breast cancer.
    Cell death & disease, 2020, 09-17, Volume: 11, Issue:9

    Topics: Animals; Apoptosis; Caspases; Cell Movement; Cell Survival; Cytochromes c; Disease Progression; Enzyme Activation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Inflammation; Intramolecular Oxidoreductases; Isoxazoles; Macrophage Migration-Inhibitory Factors; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Morpholines; Neoplasm Metastasis; Neoplasm Transplantation; Treatment Outcome; Triple Negative Breast Neoplasms; Wound Healing

2020
GW4064 attenuates lipopolysaccharide‑induced hepatic inflammation and apoptosis through inhibition of the Toll‑like receptor 4‑mediated p38 mitogen‑activated protein kinase signaling pathway in mice.
    International journal of molecular medicine, 2018, Volume: 41, Issue:3

    Topics: Alanine Transaminase; Animals; Apoptosis; Inflammation; Isoxazoles; Lipopolysaccharides; Liver; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Receptors, Cytoplasmic and Nuclear; Toll-Like Receptor 4

2018
A mechanistic approach to explore the neuroprotective potential of zonisamide in seizures.
    Inflammopharmacology, 2018, Volume: 26, Issue:4

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Epilepsy; Free Radicals; Inflammation; Isoxazoles; Male; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Seizures; Zonisamide

2018
Indolyl-isoxazolidines attenuate LPS-stimulated pro-inflammatory cytokines and increase survival in a mouse model of sepsis: Identification of potent lead.
    European journal of medicinal chemistry, 2018, Jun-10, Volume: 153

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Inflammation; Interleukin-6; Isoxazoles; Lipopolysaccharides; Mice; Sepsis; Tumor Necrosis Factor-alpha

2018
Effects of alpha-7 nicotinic allosteric modulator PNU 120596 on depressive-like behavior after lipopolysaccharide administration in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2018, 08-30, Volume: 86

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antidepressive Agents; Calcium-Binding Proteins; Cholinergic Agents; Depressive Disorder; Disease Models, Animal; Hippocampus; Inflammation; Isoxazoles; Lipopolysaccharides; Male; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Motor Activity; Phenylurea Compounds; Prefrontal Cortex

2018
Garcinol, an effective monoamine oxidase-B inhibitor for the treatment of Parkinson's disease.
    Medical hypotheses, 2018, Volume: 117

    Topics: Humans; Inflammation; Isoxazoles; Levodopa; Ligands; Molecular Conformation; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxidative Stress; Parkinson Disease; Phytochemicals; Phytotherapy; Reactive Oxygen Species; Terpenes; Zonisamide

2018
Macrophage Migration Inhibitory Factor (MIF) Inhibition in a Murine Model of Bleomycin-Induced Pulmonary Fibrosis.
    International journal of molecular sciences, 2018, Dec-18, Volume: 19, Issue:12

    Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Bleomycin; Disease Models, Animal; Female; Histocompatibility Antigens Class II; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Inflammation; Intramolecular Oxidoreductases; Isoxazoles; Lung; Macrophage Migration-Inhibitory Factors; Male; Mice; Receptors, CXCR4; Vascular Remodeling

2018
Inhibition of macrophage migration inhibitory factor attenuates inflammation and fetal kidney injury in a rat model of acute pancreatitis in pregnancy.
    International immunopharmacology, 2019, Volume: 68

    Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Female; Fetus; Inflammation; Interleukin-1beta; Intramolecular Oxidoreductases; Isoxazoles; Kidney; Macrophage Migration-Inhibitory Factors; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pancreas; Pancreatitis, Acute Necrotizing; Pregnancy; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

2019
Alpha-7 nicotinic receptor allosteric modulator PNU120596 prevents lipopolysaccharide-induced anxiety, cognitive deficit and depression-like behaviors in mice.
    Behavioural brain research, 2019, 07-02, Volume: 366

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antidepressive Agents; Anxiety; Anxiety Disorders; Astrocytes; Cognition; Cognition Disorders; Cognitive Dysfunction; Cytokines; Depression; Depressive Disorder, Major; Disease Models, Animal; Hippocampus; Inflammation; Isoxazoles; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Phenylurea Compounds; Prefrontal Cortex

2019
Effects of Parecoxib on Pain Threshold and Inflammatory Factors IL-1β, IL-6 and TNF-
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2019, Volume: 29, Issue:6

    Topics: Animals; Bone Neoplasms; Cancer Pain; Cyclooxygenase 2 Inhibitors; Down-Regulation; Female; Hyperalgesia; Inflammation; Interleukin-1beta; Interleukin-6; Isoxazoles; Pain Threshold; Random Allocation; Rats; Rats, Sprague-Dawley; Spinal Cord; Tumor Necrosis Factor-alpha

2019
New selective inhibitors of MMP-13 for inflammatory diseases: a patent evaluation (W02012151158).
    Expert opinion on therapeutic patents, 2013, Volume: 23, Issue:5

    Topics: Animals; Drug Design; Humans; Inflammation; Isoxazoles; Matrix Metalloproteinase 13; Matrix Metalloproteinase Inhibitors; Patents as Topic

2013
A novel disease-modifying antirheumatic drug, iguratimod, ameliorates murine arthritis by blocking IL-17 signaling, distinct from methotrexate and leflunomide.
    Journal of immunology (Baltimore, Md. : 1950), 2013, Nov-15, Volume: 191, Issue:10

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Chromones; Collagen; I-kappa B Kinase; Inflammation; Interleukin-17; Isoxazoles; Leflunomide; Male; Methotrexate; Mice; Mice, Inbred DBA; Phosphorylation; Signal Transduction; Sulfonamides; Synovial Membrane; TNF Receptor-Associated Factor 5

2013
Migration inhibitory factor enhances inflammation via CD74 in cartilage end plates with Modic type 1 changes on MRI.
    Clinical orthopaedics and related research, 2014, Volume: 472, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Antibodies; Antigens, Differentiation, B-Lymphocyte; Cartilage; Cells, Cultured; Chondrocytes; Female; Histocompatibility Antigens Class II; Humans; Inflammation; Inflammation Mediators; Intramolecular Oxidoreductases; Isoxazoles; Macrophage Migration-Inhibitory Factors; Magnetic Resonance Imaging; Male; Middle Aged; RNA, Messenger; Signal Transduction

2014
Small molecule inhibitors targeting activator protein 1 (AP-1).
    Journal of medicinal chemistry, 2014, Aug-28, Volume: 57, Issue:16

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Benzophenones; Biological Products; Humans; Inflammation; Isoxazoles; Maleimides; Molecular Targeted Therapy; Neoplasms; Organic Chemicals; Quinazolines; Signal Transduction; Small Molecule Libraries; Transcription Factor AP-1; Transcription Factors

2014
Intramuscular administration of paliperidone palmitate extended-release injectable microsuspension induces a subclinical inflammatory reaction modulating the pharmacokinetics in rats.
    Journal of pharmaceutical sciences, 2014, Volume: 103, Issue:7

    Topics: Animals; Delayed-Action Preparations; Immunohistochemistry; Inflammation; Injections, Intramuscular; Isoxazoles; Male; Microscopy, Electron, Transmission; Models, Biological; Muscle, Skeletal; Nanoparticles; Paliperidone Palmitate; Palmitates; Particle Size; Prodrugs; Rats, Wistar; Surface Properties; Suspensions; Tissue Distribution

2014
Soluble DPP4 induces inflammation and proliferation of human smooth muscle cells via protease-activated receptor 2.
    Biochimica et biophysica acta, 2014, Volume: 1842, Issue:9

    Topics: Amino Acid Sequence; Blotting, Western; Cell Proliferation; Cells, Cultured; Cytokines; Dipeptides; Dipeptidyl Peptidase 4; Enzyme-Linked Immunosorbent Assay; Humans; Inflammation; Isoxazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type II; Phosphorylation; Real-Time Polymerase Chain Reaction; Receptor, PAR-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Sequence Homology, Amino Acid

2014
Synthesis of new isoxazoline derivatives from harmine and evaluation of their anti-Alzheimer, anti-cancer and anti-inflammatory activities.
    Journal of enzyme inhibition and medicinal chemistry, 2015, Volume: 30, Issue:3

    Topics: Acetylcholinesterase; Alzheimer Disease; Anti-Inflammatory Agents; Antineoplastic Agents; Arachidonate 5-Lipoxygenase; Cell Proliferation; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Harmine; HCT116 Cells; Humans; Inflammation; Isoxazoles; Lipoxygenase Inhibitors; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship

2015
Association between serum uric acid and inflammation in rheumatoid arthritis: perspective on lowering serum uric acid of leflunomide.
    Clinica chimica acta; international journal of clinical chemistry, 2015, Jan-01, Volume: 438

    Topics: Aged; Arthritis, Rheumatoid; Female; Glomerular Filtration Rate; Humans; Inflammation; Isoxazoles; Leflunomide; Male; Middle Aged; Uric Acid

2015
Ultrasound composite scores for the assessment of inflammatory and structural pathologies in Psoriatic Arthritis (PsASon-Score).
    Arthritis research & therapy, 2014, Oct-31, Volume: 16, Issue:5

    Topics: Adult; Antirheumatic Agents; Arthritis, Psoriatic; Bone and Bones; Feasibility Studies; Female; Follow-Up Studies; Humans; Inflammation; Isoxazoles; Joints; Leflunomide; Male; Methotrexate; Middle Aged; Outcome Assessment, Health Care; Prospective Studies; Reproducibility of Results; Severity of Illness Index; Sulfasalazine; Surveys and Questionnaires; Synovial Membrane; Tendons; Time Factors; Ultrasonography, Doppler

2014
The Study of Different Approaches of Parecoxib Sodium Pretreatment on the Behavior of Rats with Neuropathic Pain.
    Cell biochemistry and biophysics, 2015, Volume: 72, Issue:1

    Topics: Analgesics; Animals; Disease Models, Animal; Drug Administration Schedule; Hot Temperature; Inflammation; Injections, Intraperitoneal; Injections, Spinal; Isoxazoles; Male; Neuralgia; Pain Management; Pain Measurement; Random Allocation; Rats; Rats, Sprague-Dawley; Spinal Nerves

2015
Administration of the inverse benzodiazepine agonist MRK-016 rescues acquisition and memory consolidation following peripheral administration of bacterial endotoxin.
    Behavioural brain research, 2015, Jul-15, Volume: 288

    Topics: Animals; Brain-Derived Neurotrophic Factor; Conditioning, Psychological; Fear; Freezing Reaction, Cataleptic; Hippocampus; Inflammation; Insulin-Like Growth Factor I; Isoxazoles; Learning; Lipopolysaccharides; Male; Memory; Mice, Inbred C57BL; Neuroimmunomodulation; Nootropic Agents; RNA, Messenger; Time Factors; Triazines

2015
3,5-Disubstituted Isoxazole Derivatives: Potential Inhibitors of Inflammation and Cancer.
    Inflammation, 2016, Volume: 39, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Binding Sites; Carcinoma, Ehrlich Tumor; Catalytic Domain; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; HeLa Cells; Humans; Inflammation; Isoxazoles; Lipoxygenase; Lipoxygenase Inhibitors; Mice; Molecular Docking Simulation; Thiophenes

2016
[Effect of Leflunomideon Inflammatory Factors and Immune Function in Rats with Chronic Glomerulonephritis].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2016, Volume: 47, Issue:2

    Topics: Animals; Chronic Disease; Disease Models, Animal; Glomerulonephritis; Inflammation; Interleukin-6; Isoxazoles; Leflunomide; Rats; RNA, Messenger; Serum Albumin, Bovine; Tumor Necrosis Factor-alpha

2016
JAK-STAT6 Pathway Inhibitors Block Eotaxin-3 Secretion by Epithelial Cells and Fibroblasts from Esophageal Eosinophilia Patients: Promising Agents to Improve Inflammation and Prevent Fibrosis in EoE.
    PloS one, 2016, Volume: 11, Issue:6

    Topics: Cell Line, Transformed; Chemokine CCL26; Chemokines, CC; Eosinophilic Esophagitis; Eosinophils; Epithelial Cells; Fibroblasts; Fibrosis; Gene Expression Regulation; Humans; Inflammation; Interleukin-13; Interleukin-4; Isoxazoles; Janus Kinase 1; Leflunomide; Nitriles; Omeprazole; Phosphorylation; Primary Cell Culture; Pyrazoles; Pyrimidines; Signal Transduction; STAT6 Transcription Factor; Th2 Cells

2016
Inhibition of Macrophage Migration Inhibitory Factor Protects against Inflammation and Matrix Deposition in Kidney Tissues after Injury.
    Mediators of inflammation, 2016, Volume: 2016

    Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aristolochic Acids; Blotting, Western; Cell Line; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Epithelial-Mesenchymal Transition; Fluorescent Antibody Technique; Immunohistochemistry; Inflammation; Intramolecular Oxidoreductases; Isoxazoles; Kidney; Macrophage Migration-Inhibitory Factors; Macrophages; Male; Rats; Rats, Sprague-Dawley; Ureteral Obstruction

2016
Anti-inflammatory properties of an isoxazole derivative - MZO-2.
    Pharmacological reports : PR, 2016, Volume: 68, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cell Proliferation; Cells, Cultured; Edema; Female; Humans; Hypersensitivity, Delayed; Immunity, Humoral; Inflammation; Isoxazoles; Leukocytes, Mononuclear; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Ovalbumin; Phytohemagglutinins; Sheep; Tumor Necrosis Factor-alpha

2016
[Effect of parecoxib on hippocampal inflammation and memory function in aged rats after splenectomy].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2016, Jun-28, Volume: 41, Issue:6

    Topics: Animals; Cyclooxygenase 2; Hippocampus; Inflammation; Interleukin-1beta; Isoxazoles; Male; Memory; Rats; Rats, Sprague-Dawley; Splenectomy; Tumor Necrosis Factor-alpha

2016
Sex Differences and Drug Dose Influence the Role of the α7 Nicotinic Acetylcholine Receptor in the Mouse Dextran Sodium Sulfate-Induced Colitis Model.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2017, Apr-01, Volume: 19, Issue:4

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Bridged Bicyclo Compounds, Heterocyclic; Colitis; Dextran Sulfate; Disease Models, Animal; Female; Inflammation; Isoxazoles; Male; Mice; Mice, Knockout; Phenylurea Compounds; Quinuclidines

2017
A Novel Approach for the Control of Inflammatory Pain: Prostaglandin E2 Complexation by Randomly Methylated β-Cyclodextrins.
    Anesthesia and analgesia, 2017, Volume: 124, Issue:2

    Topics: Animals; beta-Cyclodextrins; Computer Simulation; Cyclooxygenase 2 Inhibitors; Dinoprostone; Electrophoresis, Capillary; Hyperalgesia; Inflammation; Inflammation Mediators; Isoxazoles; Male; Methylation; Pain; Pain Measurement; Pain Threshold; Postural Balance; Rats; Rats, Wistar

2017
Reduced GABAergic transmission in the ventrobasal thalamus contributes to thermal hyperalgesia in chronic inflammatory pain.
    Scientific reports, 2017, 02-02, Volume: 7

    Topics: Animals; Chronic Pain; Extracellular Space; Freund's Adjuvant; GABAergic Neurons; gamma-Aminobutyric Acid; Gene Knockout Techniques; Hyperalgesia; Inflammation; Isoxazoles; Male; Muscimol; Optogenetics; Patch-Clamp Techniques; Protein Subunits; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptic Transmission; Thalamus

2017
The active metabolite of leflunomide, A77 1726, attenuates inflammatory arthritis in mice with spontaneous arthritis via induction of heme oxygenase-1.
    Journal of translational medicine, 2017, 02-13, Volume: 15, Issue:1

    Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Differentiation; Crotonates; Forkhead Transcription Factors; Heme Oxygenase-1; Humans; Hydroxybutyrates; Inflammation; Isoxazoles; Jurkat Cells; Leflunomide; Mice, Inbred BALB C; Mice, Inbred C57BL; NF-E2-Related Factor 2; Nitric Oxide Synthase Type II; Nitriles; Oxidative Stress; Signal Transduction; Spleen; Th17 Cells; Toluidines; Tyrosine

2017
Zonisamide suppresses pain symptoms of formalin-induced inflammatory and streptozotocin-induced diabetic neuropathy.
    Journal of pharmacological sciences, 2008, Volume: 107, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Formaldehyde; Inflammation; Isoxazoles; Male; Mice; Pain; Streptozocin; Zonisamide

2008
Comparison of the novel subtype-selective GABAA receptor-positive allosteric modulator NS11394 [3'-[5-(1-hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile] with diazepam, zolpidem, bretazenil, and gaboxadol in rat models of inflammatory
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 327, Issue:3

    Topics: Allosteric Regulation; Animals; Benzimidazoles; Benzodiazepinones; Diazepam; GABA Modulators; Humans; Inflammation; Isoxazoles; Neuralgia; Pyridines; Rats; Receptors, GABA-A; Zolpidem

2008
COX-2 expression and function in the hyperalgesic response to paw inflammation in mice.
    Prostaglandins, leukotrienes, and essential fatty acids, 2008, Volume: 79, Issue:6

    Topics: Animals; Blotting, Western; Brain; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Edema; Gene Expression Regulation, Enzymologic; Hindlimb; Hyperalgesia; Inflammation; Isoxazoles; Mice; Mice, Inbred C57BL; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; Spinal Cord; Zymosan

2008
Lack of correlation between the central anti-nociceptive and peripheral anti-inflammatory effects of selective COX-2 inhibitor parecoxib.
    Brain research bulletin, 2009, Aug-28, Volume: 80, Issue:1-2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Extremities; Inflammation; Isoenzymes; Isoxazoles; Ketoprofen; Male; Membrane Proteins; Rats; Rats, Sprague-Dawley

2009
Parecoxib does not suppress thromboxane synthesis in newborn piglets with group B streptococcal sepsis.
    Prostaglandins & other lipid mediators, 2009, Volume: 90, Issue:1-2

    Topics: Animals; Animals, Newborn; Cyclooxygenase 2 Inhibitors; Dinoprostone; Epoprostenol; Gene Expression Regulation; Hemodynamics; Indomethacin; Inflammation; Isoxazoles; Lung; Platelet Count; Receptors, Prostaglandin E; Sepsis; Streptococcal Infections; Streptococcus agalactiae; Swine; Thromboxanes

2009
Role of macrophage migration inhibitory factor in influenza H5N1 virus pneumonia.
    Acta virologica, 2009, Volume: 53, Issue:4

    Topics: Animals; Chemokines; Cytokines; Female; Inflammation; Influenza A Virus, H5N1 Subtype; Intramolecular Oxidoreductases; Isoxazoles; Lung; Macrophage Migration-Inhibitory Factors; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Pneumonia, Viral; RNA, Messenger

2009
Spinal macrophage migration inhibitory factor contributes to the pathogenesis of inflammatory hyperalgesia in rats.
    Pain, 2010, Volume: 148, Issue:2

    Topics: Analysis of Variance; Animals; CD47 Antigen; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Formaldehyde; Functional Laterality; Glial Fibrillary Acidic Protein; Hyperalgesia; Inflammation; Injections, Spinal; Intramolecular Oxidoreductases; Isoxazoles; Lectins; Macrophage Migration-Inhibitory Factors; Male; Microglia; Mitogen-Activated Protein Kinase Kinases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spinal Cord; tau Proteins; Up-Regulation

2010
Inflammatory gene profile in early rheumatoid arthritis and modulation by leflunomide and prednisone treatment.
    Annals of the New York Academy of Sciences, 2010, Volume: 1193

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Case-Control Studies; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Gene Expression Profiling; Gene Expression Regulation; Glucocorticoids; Humans; Inflammation; Isoxazoles; Leflunomide; Leukocytes, Mononuclear; Male; Microarray Analysis; Middle Aged; Prednisone; RNA, Messenger; Time Factors; Treatment Outcome

2010
KST5468, a new T-type calcium channel antagonist, has an antinociceptive effect on inflammatory and neuropathic pain models.
    Pharmacology, biochemistry, and behavior, 2010, Volume: 97, Issue:2

    Topics: Analgesics; Animals; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Channels, T-Type; Extracellular Signal-Regulated MAP Kinases; Formaldehyde; Gene Expression; Genes, fos; Hot Temperature; Inflammation; Injections, Intraperitoneal; Injections, Intravenous; Isoxazoles; Male; Mice; Mice, Inbred ICR; Neuralgia; Pain Measurement; Piperazines; Postural Balance; Reaction Time

2010
Targeting oxidative stress, mitochondrial dysfunction and neuroinflammatory signaling by selective cyclooxygenase (COX)-2 inhibitors mitigates MPTP-induced neurotoxicity in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jun-01, Volume: 35, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Caspase 3; Catatonia; Cyclooxygenase 2 Inhibitors; Inflammation; Isoxazoles; Lipid Peroxidation; Male; Malondialdehyde; Mice; Mitochondria; Motor Activity; MPTP Poisoning; NADH Dehydrogenase; Neuroprotective Agents; Nitrites; Nitrobenzenes; Oxidative Stress; Signal Transduction; Sulfhydryl Compounds; Sulfonamides; Tetrazolium Salts; Thiazoles; Thiobarbituric Acid Reactive Substances; Transcription Factor RelA

2011
A role for macrophage migration inhibitory factor in protective immunity against Aspergillus fumigatus.
    Immunobiology, 2011, Volume: 216, Issue:9

    Topics: Adaptive Immunity; Animals; Aspergillosis; Aspergillus fumigatus; Cytokines; Enzyme Inhibitors; Female; Immunity, Innate; Inflammation; Intramolecular Oxidoreductases; Isoxazoles; Macrophage Migration-Inhibitory Factors; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction

2011
Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110).
    British journal of pharmacology, 2012, Volume: 165, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Calcium; Cell Line; Dipeptides; Edema; HT29 Cells; Humans; Inflammation; Isoxazoles; Oligopeptides; Peptides; Piperidines; Rats; Receptor, PAR-1; Receptor, PAR-2; Spiro Compounds; Trypsin

2012
Lysophosphatidic acid receptor 1 modulates lipopolysaccharide-induced inflammation in alveolar epithelial cells and murine lungs.
    American journal of physiology. Lung cellular and molecular physiology, 2011, Volume: 301, Issue:4

    Topics: Animals; Bronchi; Bronchoalveolar Lavage Fluid; Cells, Cultured; Epithelial Cells; Gene Expression Regulation; Inflammation; Interleukin-6; Interleukin-8; Isoxazoles; Lipopolysaccharide Receptors; Lipopolysaccharides; Lysophospholipids; Male; Membrane Microdomains; Mice; Mice, Knockout; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Propionates; Pulmonary Alveoli; Receptor Cross-Talk; Receptors, Lysophosphatidic Acid; Signal Transduction

2011
Experimental study of leflunomide on renal protective effect and on inflammatory response of streptozotocin induced diabetic rats.
    Nephrology (Carlton, Vic.), 2012, Volume: 17, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Chemokine CCL2; Creatinine; Cytoprotection; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gene Expression Regulation; Immunohistochemistry; Immunosuppressive Agents; Inflammation; Inflammation Mediators; Isoxazoles; Kidney; Leflunomide; Male; Nephrectomy; NF-kappa B; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha

2012
Protective effect of PNU-120596, a selective alpha7 nicotinic acetylcholine receptor-positive allosteric modulator, on myocardial ischemia-reperfusion injury in rats.
    Journal of cardiovascular pharmacology, 2012, Volume: 59, Issue:6

    Topics: Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Cytokines; Disease Models, Animal; Inflammation; Isoxazoles; Lipid Peroxidation; Male; Myocardial Infarction; Myocardial Reperfusion Injury; NF-kappa B; Nicotinic Agonists; Phenylurea Compounds; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic

2012
Identification of a novel series of BET family bromodomain inhibitors: binding mode and profile of I-BET151 (GSK1210151A).
    Bioorganic & medicinal chemistry letters, 2012, Apr-15, Volume: 22, Issue:8

    Topics: Animals; Binding Sites; Crystallography, X-Ray; Guinea Pigs; Heterocyclic Compounds, 4 or More Rings; Inflammation; Isoxazoles; Mice; Models, Molecular; Nerve Tissue Proteins; Protein Binding; Quinolines; Rats

2012
The α7 nicotinic ACh receptor agonist compound B and positive allosteric modulator PNU-120596 both alleviate inflammatory hyperalgesia and cytokine release in the rat.
    British journal of pharmacology, 2012, Volume: 167, Issue:2

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azabicyclo Compounds; Carrageenan; Cytokines; Diclofenac; Freund's Adjuvant; Gene Expression Regulation; Hyperalgesia; Inflammation; Isoxazoles; Male; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Thiophenes

2012
The HIV matrix protein p17 subverts nuclear receptors expression and induces a STAT1-dependent proinflammatory phenotype in monocytes.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Atherosclerosis; Cell Line; Cell Separation; gag Gene Products, Human Immunodeficiency Virus; Gene Expression Regulation; GTP-Binding Proteins; HIV Antigens; HIV Infections; HIV-1; Humans; Inflammation; Isoxazoles; Janus Kinases; Lipid Metabolism; Lipopolysaccharide Receptors; Macrophages; Monocytes; Neoplasm Proteins; Neutralization Tests; Phenotype; Phosphorylation; PPAR gamma; Receptors for Activated C Kinase; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Signal Transduction; STAT1 Transcription Factor; Thiazolidinediones; Vaccination; Vidarabine

2012
Relationship between inflammation and metabolic syndrome following treatment with paliperidone for schizophrenia.
    Progress in neuro-psychopharmacology & biological psychiatry, 2012, Dec-03, Volume: 39, Issue:2

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Delayed-Action Preparations; Female; Humans; Inflammation; Isoxazoles; Leukocyte Count; Male; Metabolic Syndrome; Middle Aged; Paliperidone Palmitate; Pyrimidines; Schizophrenia

2012
Effects of α7 positive allosteric modulators in murine inflammatory and chronic neuropathic pain models.
    Neuropharmacology, 2013, Volume: 65

    Topics: Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Disease Models, Animal; Inflammation; Isoxazoles; Male; Mice; Mice, Inbred ICR; Neuralgia; Nicotinic Agonists; Phenylurea Compounds; Receptors, Nicotinic; Treatment Outcome

2013
Aryl hydrocarbon receptor agonist, leflunomide, protects the ischemic-reperfused kidney: role of Tregs and stem cells.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2012, Volume: 303, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Gene Expression Regulation; Inflammation; Isoxazoles; Kidney; Leflunomide; Male; Mice; Mice, Inbred C57BL; Receptors, Aryl Hydrocarbon; Reperfusion Injury; Stem Cells; T-Lymphocytes, Regulatory

2012
Leflunomide analogues as potential antiinflammatory agents.
    Chemical & pharmaceutical bulletin, 2003, Volume: 51, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Edema; Inflammation; Isoxazoles; Leflunomide; Male; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley

2003
Anti-hyperalgesic activity of the cox-2 inhibitor lumiracoxib in a model of bone cancer pain in the rat.
    Pain, 2004, Volume: 107, Issue:1-2

    Topics: Analysis of Variance; Animals; Behavior, Animal; Bone Density; Bone Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Hyperalgesia; Inflammation; Isoenzymes; Isoxazoles; Organic Chemicals; Pain; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Radiology; Rats; Rats, Sprague-Dawley; Sulfonamides; Time Factors; Tumor Cells, Cultured

2004
Valdecoxib: assessment of cyclooxygenase-2 potency and selectivity.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Hyperalgesia; Inflammation; Isoxazoles; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Sulfonamides

2005
Comparison of anti-arthritic properties of leflunomide with methotrexate and FK506: effect on T cell activation-induced inflammatory cytokine production in vitro and rat adjuvant-induced arthritis.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2004, Volume: 53, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Bone Marrow Cells; CD28 Antigens; CD3 Complex; Cell Proliferation; Cytokines; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunosuppressive Agents; Inflammation; Isoxazoles; Leflunomide; Leukocytes; Leukocytes, Mononuclear; Lymphocyte Activation; Methotrexate; Mice; Neutrophils; Random Allocation; Rats; Rats, Inbred Lew; T-Lymphocytes; Tacrolimus; Time Factors

2004
Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes.
    Cytokine, 2005, Sep-07, Volume: 31, Issue:5

    Topics: Active Transport, Cell Nucleus; Aniline Compounds; Anti-Inflammatory Agents; Apoptosis; Arthritis, Rheumatoid; Cells, Cultured; Crotonates; Cyclooxygenase 2; Cytokines; Dinoprostone; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; Hydroxybutyrates; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-10; Interleukin-11; Interleukin-8; Isoxazoles; Leflunomide; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Receptors, Tumor Necrosis Factor, Type I; Sialoglycoproteins; Synovial Fluid; Time Factors; Toluidines; Trypsin

2005
Activatory properties of lysophosphatidic acid on human THP-1 cells.
    Inflammation, 2007, Volume: 30, Issue:5

    Topics: Arachidonic Acid; Cell Line; Cell Proliferation; Dinoprostone; DNA Replication; Enzyme Activation; Humans; Inflammation; Inflammation Mediators; Isoxazoles; Leukotriene B4; Lysophospholipids; Monocytes; NADPH Oxidases; Propionates; Reactive Oxygen Species; Receptors, Lysophosphatidic Acid; RNA, Messenger; Time Factors; Up-Regulation

2007
Polyamines in inflammation and their modulation by conventional anti-inflammatory drugs.
    Indian journal of experimental biology, 2007, Volume: 45, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cell Proliferation; Cyclooxygenase Inhibitors; Dexamethasone; Diclofenac; Drug Interactions; Inflammation; Isoxazoles; Polyamines; Rats; Rats, Wistar; Steroids; Sulfonamides

2007
Farnesoid x receptor ligands inhibit vascular smooth muscle cell inflammation and migration.
    Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Becaplermin; Cell Line; Cell Movement; Cell Survival; Cells, Cultured; Chenodeoxycholic Acid; Cyclooxygenase 2; DNA-Binding Proteins; Dose-Response Relationship, Drug; Genes, Reporter; Humans; Inflammation; Interleukin-1beta; Isoxazoles; Ligands; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Nitric Oxide Synthase Type II; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Receptors, Cytoplasmic and Nuclear; RNA Interference; RNA, Messenger; RNA, Small Interfering; Transcription Factors; Transcription, Genetic; Transfection

2007
Chemical and biological investigation of N-hydroxy-valdecoxib: An active metabolite of valdecoxib.
    Bioorganic & medicinal chemistry, 2008, May-01, Volume: 16, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cattle; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Humans; Hyperalgesia; Inflammation; Isoxazoles; Male; Models, Molecular; Molecular Structure; Pain; Pain Measurement; Rabbits; Rats; Rats, Wistar; Recombinant Proteins; Stereoisomerism; Sulfonamides; Time Factors

2008
Synthesis and topical antiinflammatory activity of some steroidal [16 alpha, 17 alpha-d]Isoxazolidines.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:12

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Chemical Phenomena; Chemistry; Croton Oil; Glucocorticoids; Inflammation; Isoxazoles; Mice; Oxazoles

1982
Leflunomide effectively treats naturally occurring immune-mediated and inflammatory diseases of dogs that are unresponsive to conventional therapy.
    Transplantation proceedings, 1998, Volume: 30, Issue:8

    Topics: Aniline Compounds; Animals; Crotonates; Dog Diseases; Dogs; Female; Hydroxybutyrates; Immune System Diseases; Immunosuppressive Agents; Inflammation; Isoxazoles; Leflunomide; Male; Nitriles; Syndrome; Toluidines

1998
Pulmonary eosinophilia in a murine model of allergic inflammation is attenuated by small molecule alpha4beta1 antagonists.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 301, Issue:2

    Topics: Animals; Anti-Allergic Agents; Disease Models, Animal; Humans; Hypersensitivity; Inflammation; Integrin alpha4beta1; Integrins; Isoxazoles; Jurkat Cells; Mice; Phenylurea Compounds; Pulmonary Eosinophilia; Receptors, Lymphocyte Homing; Vascular Cell Adhesion Molecule-1

2002
Synthesis and anti-inflammatory activity of 3,3a-dihydro-2H,9H-isoxazolo [3,2-b] [1,3]benzoxazin-9-ones and related compounds.
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Fever; Inflammation; Isoxazoles; Male; Oxazines; Rats; Structure-Activity Relationship

1977
The anti=inflammatory properties of isoxicam (4-hydroxy-2methyl-N-(5-methyl-3isoxolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide).
    Agents and actions, 1975, Volume: 5, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carrageenan; Inflammation; Isoxazoles; Male; Oxazoles; Peptic Ulcer; Piroxicam; Rats; Thiazines

1975
6-Sulfanilamidoindazole arthritis in rats: influence of the new anti-inflammatory agent CGP 28237 and of the immunomodulating compound HWA 486 on degree of arthritis and on acute phase reaction.
    Die Pharmazie, 1988, Volume: 43, Issue:1

    Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Indans; Indenes; Inflammation; Isoxazoles; Leflunomide; Oxazoles; Rats; Sulfanilamides

1988