Compounds > isoxazoles
Page last updated: 2024-08-21

isoxazoles and Head and Neck Neoplasms

isoxazoles has been researched along with Head and Neck Neoplasms in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's6 (60.00)24.3611
2020's3 (30.00)2.80

Authors

AuthorsStudies
Distel, L; Dobler, C; Fietkau, R; Hecht, M; Jost, T1
Bürkel, F; Distel, LV; Faulhaber, EM; Fietkau, R; Hecht, M; Jost, T; Scheper, J; Symank, J1
Chen, Q; Chen, S; Cheng, X; Li, F; Tao, Z; Wang, Y; Xiao, B; Xiao, Y1
Abbadessa, A; Amata, E; Castilho, RM; Floresta, G; Mineo, PG; Monciino, G; Nicosia, A; Pistarà, V; Rescifina, A; Varrica, MG; Zagni, C1
Peters, GJ1
Bussink, J; Grénman, R; Iida, M; Kaanders, JH; Peeters, WJ; Span, PN; Stegeman, H; van der Kogel, AJ; Verheijen, MM; Wheeler, DL1
Aleksic, T; Allen, P; Asher, R; Ashraf, SQ; Ashworth, A; Athanasou, N; Bailey, D; Bajrami, I; Blay, JY; Bodmer, WF; Feller, S; Gao, S; Han, C; Jones, TM; Kashima, T; Kigozi, A; Lord, CJ; Macaulay, VM; Machiels, JP; Middleton, MR; Ouaret, D; Schmitz, S; Thalmann, G; Upile, N; Verrill, C; Wilding, JL1
Barker, HE; Bhide, SA; Dillon, M; Harrington, KJ; Khan, AA; Kyula, JN; Mansfield, DC; McLaughlin, M; Newbold, KL; Nutting, CM; Patel, R; Pedersen, M1
Fukazawa, T; Honami, T; Ibaragi, S; Mohammad Monsur Hassan, N; Naomoto, Y; Okui, T; Sasaki, A; Shimo, T; Takaoka, M1
Cherrington, JM; Kabbinavar, F; Mann, E; Schwartz, DP; Shawver, LK; Slamon, DJ; Strawn, LM1

Other Studies

10 other study(ies) available for isoxazoles and Head and Neck Neoplasms

ArticleYear
Senescence Induction by Combined Ionizing Radiation and DNA Damage Response Inhibitors in Head and Neck Squamous Cell Carcinoma Cells.
    Cells, 2020, 09-01, Volume: 9, Issue:9

    Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Line, Tumor; Cellular Senescence; DNA Damage; Fibroblasts; Head and Neck Neoplasms; Humans; Isoxazoles; Male; Protein Kinase Inhibitors; Pyrazines; Pyridines; Quinolines; Radiation, Ionizing; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; TOR Serine-Threonine Kinases; Triazoles

2020
Kinase Inhibitors of DNA-PK, ATM and ATR in Combination with Ionizing Radiation Can Increase Tumor Cell Death in HNSCC Cells While Sparing Normal Tissue Cells.
    Genes, 2021, 06-17, Volume: 12, Issue:6

    Topics: Ataxia Telangiectasia Mutated Proteins; Carcinoma, Squamous Cell; Cell Death; Cell Line, Tumor; Cells, Cultured; DNA Repair; DNA-Activated Protein Kinase; Head and Neck Neoplasms; Humans; Isoxazoles; Protein Kinase Inhibitors; Pyrazines; Pyridines; Quinolines; Triazoles; X-Rays

2021
(S,R)3-(4-Hydroxyphenyl)-4,5-Dihydro-5-Isoxazole Acetic Acid Methyl Ester Inhibits Epithelial-to-Mesenchymal Transition Through TGF-β/Smad4 Axis in Nasopharyngeal Carcinoma.
    Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:6

    Topics: Acetates; Adult; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Isoxazoles; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Smad4 Protein; Squamous Cell Carcinoma of Head and Neck; Transforming Growth Factor beta

2022
DNA intercalators based on (1,10-phenanthrolin-2-yl)isoxazolidin-5-yl core with better growth inhibition and selectivity than cisplatin upon head and neck squamous cells carcinoma.
    European journal of medicinal chemistry, 2018, Jan-01, Volume: 143

    Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Head and Neck Neoplasms; Humans; Intercalating Agents; Isoxazoles; Models, Molecular; Molecular Structure; Squamous Cell Carcinoma of Head and Neck; Structure-Activity Relationship

2018
Antipyrimidine effects of five different pyrimidine de novo synthesis inhibitors in three head and neck cancer cell lines.
    Nucleosides, nucleotides & nucleic acids, 2018, Volume: 37, Issue:6

    Topics: Amides; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Biphenyl Compounds; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Carcinoma, Squamous Cell; Cell Line, Tumor; Dihydroorotate Dehydrogenase; Head and Neck Neoplasms; Humans; Isoxazoles; Naphthoquinones; Orotate Phosphoribosyltransferase; Oxidoreductases Acting on CH-CH Group Donors; Phosphonoacetic Acid; Purine Nucleotides; Pyrazoles; Pyrimidine Nucleotides; Ribonucleosides; Ribose

2018
Combining radiotherapy with MEK1/2, STAT5 or STAT6 inhibition reduces survival of head and neck cancer lines.
    Molecular cancer, 2013, Nov-05, Volume: 12, Issue:1

    Topics: Antineoplastic Agents; Butadienes; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Chemoradiotherapy; Dasatinib; Drug Screening Assays, Antitumor; Head and Neck Neoplasms; Humans; Imidazoles; Isoxazoles; Leflunomide; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Nitriles; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Radiation Tolerance; STAT5 Transcription Factor; STAT6 Transcription Factor; Thiazoles; Tumor Suppressor Proteins

2013
Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling.
    Cancer research, 2014, Oct-15, Volume: 74, Issue:20

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Dishevelled Proteins; Drug Resistance, Neoplasm; Gene Expression; Head and Neck Neoplasms; Humans; Inhibitory Concentration 50; Insulin-Like Growth Factor I; Isoxazoles; Male; MAP Kinase Signaling System; Mice; Phosphoproteins; Pyrimidines; ras Proteins; Receptor, IGF Type 1; Wnt Proteins; Xenograft Model Antitumor Assays

2014
HSP90 inhibition sensitizes head and neck cancer to platin-based chemoradiotherapy by modulation of the DNA damage response resulting in chromosomal fragmentation.
    BMC cancer, 2017, 01-31, Volume: 17, Issue:1

    Topics: Animals; BRCA1 Protein; Carcinoma, Squamous Cell; Cell Line, Tumor; Chemoradiotherapy; Chromosomes; DNA Damage; DNA Fragmentation; DNA Repair; Female; Head and Neck Neoplasms; Homologous Recombination; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Mice, Inbred BALB C; Mice, Nude; Organoplatinum Compounds; Protein Kinase Inhibitors; Resorcinols; Squamous Cell Carcinoma of Head and Neck; Tumor Suppressor Protein p53

2017
Novel HSP90 inhibitor NVP-AUY922 enhances the anti-tumor effect of temsirolimus against oral squamous cell carcinoma.
    Current cancer drug targets, 2013, Volume: 13, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Line, Tumor; Cells, Cultured; Female; Head and Neck Neoplasms; HSP90 Heat-Shock Proteins; Human Umbilical Vein Endothelial Cells; Humans; Isoxazoles; Mice; Mice, Nude; Molecular Targeted Therapy; Mouth Neoplasms; Neoplasm Proteins; Neovascularization, Pathologic; Protein Kinase Inhibitors; Random Allocation; Resorcinols; Sirolimus; Squamous Cell Carcinoma of Head and Neck; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays

2013
Effects of SU101 in combination with cytotoxic agents on the growth of subcutaneous tumor xenografts.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:7

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cell Division; Cell Survival; Cisplatin; Etoposide; Glioblastoma; Head and Neck Neoplasms; Humans; Isoxazoles; Leflunomide; Lung Neoplasms; Mice; Mice, Nude; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

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