isoxazoles has been researched along with Gastrointestinal Stromal Neoplasm in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, HH; Chen, LT; Chiang, NJ; Hsueh, YS; Li, CF; Yen, CC | 1 |
| Bauer, TM; Bendell, JC; Burris, HA; Earwood, C; Joseph, M; Lamar, R; Lane, CM; Owera, R; Penley, W; Spigel, DR; Thompson, DS | 1 |
| Chen, LT; Chiang, NJ; Hsueh, YS; Li, CF; Shih, NY; Yen, CC | 1 |
1 trial(s) available for isoxazoles and Gastrointestinal Stromal Neoplasm
| Article | Year |
|---|---|
A Phase 2 Study of the Hsp90 Inhibitor AUY922 as Treatment for Patients with Refractory Gastrointestinal Stromal Tumors.
Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gastrointestinal Stromal Tumors; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Male; Middle Aged; Mutation; Resorcinols; Retreatment; Treatment Outcome; Young Adult | 2016 |
2 other study(ies) available for isoxazoles and Gastrointestinal Stromal Neoplasm
| Article | Year |
|---|---|
MTOR inhibition enhances NVP-AUY922-induced autophagy-mediated KIT degradation and cytotoxicity in imatinib-resistant gastrointestinal stromal tumors.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Benzamides; Cell Death; Cell Survival; Down-Regulation; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; HSP90 Heat-Shock Proteins; Humans; Imatinib Mesylate; Immunohistochemistry; Inhibitory Concentration 50; Isoxazoles; Mice; Mice, Inbred NOD; Mice, SCID; Mutation; Necrosis; Neoplasm Transplantation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Resorcinols; RNA Interference; RNA, Small Interfering; Sirolimus; TOR Serine-Threonine Kinases | 2014 |
Autophagy is involved in endogenous and NVP-AUY922-induced KIT degradation in gastrointestinal stromal tumors.
Topics: Antineoplastic Agents; Autophagy; Benzamides; Benzoquinones; Cell Death; Cell Extracts; Cell Line, Tumor; Down-Regulation; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Isoxazoles; Lactams, Macrocyclic; Models, Biological; Phosphorylation; Piperazines; Proteolysis; Proto-Oncogene Proteins c-kit; Pyrimidines; Resorcinols | 2013 |