isoxazoles has been researched along with Electrocardiogram QT Prolonged in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Conrad, T; Gu, K; Kankam, M; Mueller, J; Nakamura, A; Newman, LM; O'Donnell, J; Osborn, BL; Saviolakis, GA | 1 |
| Hamilton, JB; Heaton, C; Lannan, R; Lavedan, C; Licamele, L; Mack, K; Polymeropoulos, MH; Volpi, S; Wolfgang, CD | 1 |
| Eerdekens, M; Hough, DW; Kramer, M; Natarajan, J; Rossenu, S; Vandebosch, A | 1 |
| Fukui, N; Inoue, Y; Ono, S; Saito, M; Someya, T; Sugai, T; Suzuki, Y; Tsuneyama, N; Watanabe, J | 1 |
| Citrome, L | 1 |
| Berwaerts, J; Coppola, D; Gopal, S; Hough, DW; Nuamah, IF; Remmerie, BM; Sterkens, PC; Xu, Y | 1 |
| Hochfeld, M; Meng, X; Potkin, SG; Preskorn, S | 1 |
| Berecz, R; de la Rubia, A; Dorado, P; Llerena, A | 1 |
| Cutler, AJ; Polymeropoulos, MH; Weiden, PJ; Wolfgang, CD | 1 |
2 review(s) available for isoxazoles and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Iloperidone: a clinical overview.
Topics: Antipsychotic Agents; Electrocardiography; Heart Rate; Humans; Isoxazoles; Long QT Syndrome; Piperidines; Schizophrenia; Treatment Outcome; Weight Gain | 2011 |
Safety profile of iloperidone: a pooled analysis of 6-week acute-phase pivotal trials.
Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Basal Ganglia Diseases; Double-Blind Method; Female; Humans; Isoxazoles; Long QT Syndrome; Male; Middle Aged; Patient Dropouts; Piperidines; Prospective Studies; Psychotic Disorders; Randomized Controlled Trials as Topic; Schizophrenia; Weight Gain | 2008 |
5 trial(s) available for isoxazoles and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Thorough QT Study To Evaluate the Effect of Zoliflodacin, a Novel Therapeutic for Gonorrhea, on Cardiac Repolarization in Healthy Adults.
Topics: Adult; Barbiturates; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Fluoroquinolones; Gonorrhea; Healthy Volunteers; Heart Rate; Humans; Isoxazoles; Long QT Syndrome; Morpholines; Oxazolidinones; Spiro Compounds | 2021 |
Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Carrier Proteins; CELF Proteins; Cytoskeletal Proteins; Double-Blind Method; Electrocardiography; Female; Follow-Up Studies; Gene Frequency; Genome-Wide Association Study; Genotype; Humans; Intracellular Signaling Peptides and Proteins; Isoxazoles; Linear Models; Linkage Disequilibrium; Long QT Syndrome; Male; Middle Aged; Neuregulins; Organic Anion Transporters; Pharmacogenetics; Phosphoproteins; Phosphotransferases (Alcohol Group Acceptor); Piperazines; Piperidines; Polymorphism, Single Nucleotide; RNA-Binding Proteins; Schizophrenia; Thiazoles; Young Adult | 2009 |
Evaluation of the effect of paliperidone extended release and quetiapine on corrected QT intervals: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Dibenzothiazepines; Double-Blind Method; Electrocardiography; Female; Humans; Isoxazoles; Long QT Syndrome; Male; Middle Aged; Paliperidone Palmitate; Pyrimidines; Quetiapine Fumarate; Schizophrenia; Treatment Outcome | 2011 |
QT prolongation of the antipsychotic risperidone is predominantly related to its 9-hydroxy metabolite paliperidone.
Topics: Adult; Age Factors; Antipsychotic Agents; Dose-Response Relationship, Drug; Electrocardiography; Female; Humans; Isoxazoles; Long QT Syndrome; Male; Paliperidone Palmitate; Pyrimidines; Risperidone; Young Adult | 2012 |
A thorough QTc study of 3 doses of iloperidone including metabolic inhibition via CYP2D6 and/or CYP3A4 and a comparison to quetiapine and ziprasidone.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dibenzothiazepines; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Electrocardiography; Enzyme Inhibitors; Female; Genotype; Heart Rate; Humans; Isoxazoles; Ketoconazole; Linear Models; Long QT Syndrome; Male; Middle Aged; Paroxetine; Pharmacogenetics; Phenotype; Piperazines; Piperidines; Quetiapine Fumarate; Thiazoles; United States; Young Adult | 2013 |
2 other study(ies) available for isoxazoles and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Prolongation of cardiac ventricular repolarization under paliperidone: how and how much?
Topics: Animals; Antipsychotic Agents; Clinical Trials as Topic; Drug Evaluation, Preclinical; Ether-A-Go-Go Potassium Channels; Humans; Isoxazoles; Long QT Syndrome; Paliperidone Palmitate; Pyrimidines; Risk Factors | 2012 |
QTc interval, CYP2D6 and CYP2C9 genotypes and risperidone plasma concentrations.
Topics: Administration, Oral; Adult; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Drug Administration Schedule; Electrocardiography; Genotype; Humans; Isoxazoles; Long QT Syndrome; Middle Aged; Paliperidone Palmitate; Pyrimidines; Risperidone | 2004 |