Page last updated: 2024-08-21

isoxazoles and Diarrhea

isoxazoles has been researched along with Diarrhea in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.53)18.2507
2000's7 (36.84)29.6817
2010's7 (36.84)24.3611
2020's3 (15.79)2.80

Authors

AuthorsStudies
Cui, L; Li, C; Wang, S; Wang, X; Yan, Z; Zhang, Y; Zheng, Y1
Camilleri, M; Vijayvargiya, P1
Badman, MK; Bhad, P; Burton, D; Camilleri, M; Chen, J; Im, K; Nord, SL; Oduyebo, I; Sanders, DS; Walters, JRF; Zhang, Y1
Amu, S; Aviello, G; Donowitz, M; Fallon, PG; Keating, N; Keely, SJ; Mroz, MS; Sarker, R; Ward, JB1
Akimov, M; Boku, N; Doi, T; Fuse, N; Ohtsu, A; Onozawa, Y; Robson, M; Watanabe, J; Yamazaki, K; Yoshino, T1
Fowler, N; Hagemeister, F; Knickerbocker, J; Kwak, L; Nastoupil, L; Oki, Y; Romaguera, J; Samaniego, F; Westin, J; Younes, A1
Do, A; Fairlie, DP; Iyer, A; Lohman, RJ; Reid, RC; Sweet, MJ1
Berges, W; Donner, P; Gugenberger, C; Naami, A1
Bornholdt, K; Hein, G; Kellner, H1
Hameed, K; Ishaq, M; Mirza, AI; Muhammad, JS1
Cleland, LG; O'Doherty, C; Proudman, SM; Schnabl, M; Sorich, MJ; Spargo, LD; Wiese, MD1
Bathon, JM; Bensen, WM; Caldwell, JR; Cannon, GW; Coleman, P; Crawford, B; Curtis, DL; Cush, JJ; Fernando, I; Furst, DE; Genovese, MC; Kaine, JL; Kantor, SM; Keystone, E; Kopp, EJ; Kremer, JM; Lindsley, HB; Luggen, ME; Markenson, JA; Ruderman, EM; Simpson, K; Strand, V; Waltuck, J; Weisman, MH1
Vandooren, AK; Verschueren, P; Westhovens, R1
Bijlsma, JW; Geenen, R; Goldschmeding, R; Kruize, AA; van Roon, EN; van Roon, JA; van Woerkom, JM; Verstappen, SM1
Bohanec Grabar, P; Dolzan, V; Logar, D; Rozman, B; Suput, D; Tomsic, M1
Byrne, VM; Coblyn, JS; Helfgott, SM; Kaymakcian, MV; Kremer, JM; Maier, AL; Morrell, M; Strand, V; Weinblatt, ME1
Johnson, DM; Kiely, PD1

Reviews

1 review(s) available for isoxazoles and Diarrhea

ArticleYear
The Role of Bile Acids in Chronic Diarrhea.
    The American journal of gastroenterology, 2020, Volume: 115, Issue:10

    Topics: Benzothiazoles; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestenones; Cholestyramine Resin; Chronic Disease; Colesevelam Hydrochloride; Colestipol; Diarrhea; Diet, Fat-Restricted; Feces; Humans; Intestinal Mucosa; Irritable Bowel Syndrome; Isoxazoles; Liver; Malabsorption Syndromes; Receptors, Cytoplasmic and Nuclear; Sequestering Agents; Taurocholic Acid

2020

Trials

9 trial(s) available for isoxazoles and Diarrhea

ArticleYear
Randomised clinical trial: significant biochemical and colonic transit effects of the farnesoid X receptor agonist tropifexor in patients with primary bile acid diarrhoea.
    Alimentary pharmacology & therapeutics, 2020, Volume: 52, Issue:5

    Topics: Adult; Aged; Benzothiazoles; Bile; Bile Acids and Salts; Cross-Over Studies; Diarrhea; Double-Blind Method; Female; Gastrointestinal Transit; Humans; Isoxazoles; Liver; Male; Middle Aged; Receptors, Cytoplasmic and Nuclear; Treatment Outcome

2020
Phase I dose-escalation study of the HSP90 inhibitor AUY922 in Japanese patients with advanced solid tumors.
    Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:3

    Topics: Antineoplastic Agents; Asian People; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Fatigue; Female; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Male; Maximum Tolerated Dose; Middle Aged; Nausea; Neoplasms; Resorcinols; Treatment Outcome

2014
Experience with HSP90 inhibitor AUY922 in patients with relapsed or refractory non-Hodgkin lymphoma.
    Haematologica, 2015, Volume: 100, Issue:7

    Topics: Antineoplastic Agents; Diarrhea; Drug Administration Schedule; Edema; Fatigue; Female; Gene Expression; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Lymphoma, Large B-Cell, Diffuse; Lymphoma, T-Cell, Peripheral; Male; Recurrence; Remission Induction; Resorcinols; Retrospective Studies; Survival Analysis; Thrombocytopenia; Treatment Outcome

2015
Leflunomide in the treatment of patients with early rheumatoid arthritis--results of a prospective non-interventional study.
    Clinical rheumatology, 2010, Volume: 29, Issue:8

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Blood Sedimentation; Diarrhea; Female; Headache; Humans; Hypertension; Incidence; Isoxazoles; Leflunomide; Male; Middle Aged; Nausea; Prospective Studies; Treatment Outcome

2010
Leflunomide or methotrexate? Comparison of clinical efficacy and safety in low socio-economic rheumatoid arthritis patients.
    Modern rheumatology, 2011, Volume: 21, Issue:4

    Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Sedimentation; Diarrhea; Double-Blind Method; Female; Humans; Isoxazoles; Leflunomide; Male; Methotrexate; Middle Aged; Nausea; Severity of Illness Index; Social Class; Treatment Outcome

2011
Concomitant leflunomide therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate. A randomized, double-blind, placebo-controlled trial.
    Annals of internal medicine, 2002, Nov-05, Volume: 137, Issue:9

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Arthritis, Rheumatoid; Diarrhea; Disability Evaluation; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Isoxazoles; Leflunomide; Liver Function Tests; Male; Methotrexate; Middle Aged; Placebos; Quality of Life; Surveys and Questionnaires; Treatment Outcome

2002
Safety and efficacy of leflunomide in primary Sjögren's syndrome: a phase II pilot study.
    Annals of the rheumatic diseases, 2007, Volume: 66, Issue:8

    Topics: Adult; Aniline Compounds; Crotonates; Diarrhea; Facial Dermatoses; Fatigue; Female; Humans; Hydroxybutyrates; Immunoglobulin G; Immunosuppressive Agents; Isoxazoles; Leflunomide; Lupus Erythematosus, Systemic; Middle Aged; Nitriles; Pilot Projects; Sjogren's Syndrome; Statistics, Nonparametric; Toluidines; Vasculitis

2007
Pharmacokinetics, safety, and efficacy of combination treatment with methotrexate and leflunomide in patients with active rheumatoid arthritis.
    Arthritis and rheumatism, 1999, Volume: 42, Issue:7

    Topics: Adult; Alanine Transaminase; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspartate Aminotransferases; Diarrhea; Drug Therapy, Combination; Female; Humans; Isoxazoles; Leflunomide; Liver; Male; Methotrexate; Middle Aged; Nausea; Patient Compliance; Treatment Outcome

1999
Infliximab and leflunomide combination therapy in rheumatoid arthritis: an open-label study.
    Rheumatology (Oxford, England), 2002, Volume: 41, Issue:6

    Topics: Adult; Aged; Anaphylaxis; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Autoantibodies; Combined Modality Therapy; Diarrhea; Drug Eruptions; Female; Humans; Hypertension; Immunosuppressive Agents; Infections; Infliximab; Isoxazoles; Leflunomide; Liver; Male; Middle Aged; Oral Ulcer; Pilot Projects; Tumor Necrosis Factor-alpha

2002

Other Studies

9 other study(ies) available for isoxazoles and Diarrhea

ArticleYear
Heat Shock Protein 27 Regulates the Inflammatory Response of Intestinal Epithelial Cells by the Nuclear Factor-κB Pathway.
    Digestive diseases and sciences, 2020, Volume: 65, Issue:12

    Topics: Anisoles; Antimetabolites; Cells, Cultured; Diarrhea; Gene Silencing; HSP27 Heat-Shock Proteins; Humans; Inflammation; Intestinal Mucosa; Irritable Bowel Syndrome; Isoxazoles; NF-kappa B; Phosphorylation; RNA, Small Interfering; Signal Transduction

2020
Farnesoid X receptor agonists attenuate colonic epithelial secretory function and prevent experimental diarrhoea in vivo.
    Gut, 2014, Volume: 63, Issue:5

    Topics: Animals; Antidiarrheals; Blotting, Western; Caco-2 Cells; Cells, Cultured; Colon; Diarrhea; Electrodiagnosis; Humans; Intestinal Mucosa; Ion Transport; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Receptors, Cytoplasmic and Nuclear; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers

2014
An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice.
    The Journal of pharmacology and experimental therapeutics, 2017, Volume: 360, Issue:1

    Topics: Animals; B-Lymphocytes; Colitis; Colon; Cytokines; Dextran Sulfate; Diarrhea; Female; Hemorrhage; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Hydroxamic Acids; Intestinal Mucosa; Isoxazoles; Lymphocytes; Mice; Mice, Inbred C57BL; Mucins; Myeloid Cells; Neutrophil Activation; Peroxidase

2017
[Persistent diarrhea and loss of weight during therapy with leflunomide].
    Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133, Issue:34-35

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Colitis, Lymphocytic; Diabetes Mellitus, Type 1; Diarrhea; Female; Hashimoto Disease; Humans; Hypertension; Isoxazoles; Leflunomide; Middle Aged; Weight Loss

2008
Polymorphisms in cytochrome P450 2C19 enzyme and cessation of leflunomide in patients with rheumatoid arthritis.
    Arthritis research & therapy, 2012, Jul-12, Volume: 14, Issue:4

    Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Cytochrome P-450 CYP2C19; Diarrhea; Female; Follow-Up Studies; Humans; Isoxazoles; Leflunomide; Male; Middle Aged; Polymorphism, Single Nucleotide; Retrospective Studies; Withholding Treatment

2012
Summaries for patients. Combination therapy for rheumatoid arthritis.
    Annals of internal medicine, 2002, Nov-05, Volume: 137, Issue:9

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites; Arthritis, Rheumatoid; Diarrhea; Drug Therapy, Combination; Female; Humans; Isoxazoles; Leflunomide; Liver Function Tests; Male; Methotrexate; Middle Aged; Treatment Outcome

2002
Debilitating diarrhoea and weight loss due to colitis in two RA patients treated with leflunomide.
    Clinical rheumatology, 2005, Volume: 24, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy; Colitis; Colon; Colonoscopy; Diagnosis, Differential; Diarrhea; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Isoxazoles; Leflunomide; Middle Aged; Weight Loss

2005
Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients.
    European journal of clinical pharmacology, 2008, Volume: 64, Issue:9

    Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cytochrome P-450 CYP1A2; Diarrhea; Dose-Response Relationship, Drug; Female; Humans; Isoxazoles; Leflunomide; Male; Middle Aged; Nausea; Pharmacogenetics; Pilot Projects; Polymorphism, Genetic; Pruritus; Vomiting

2008
New drugs for rheumatoid arthritis.
    The Medical letter on drugs and therapeutics, 1998, Nov-20, Volume: 40, Issue:1040

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Diarrhea; Drug Interactions; Etanercept; Fees, Pharmaceutical; Humans; Immunoglobulin G; Infliximab; Isoxazoles; Leflunomide; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha

1998