isoxazoles has been researched along with Cancer of Liver in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.88) | 18.7374 |
| 1990's | 3 (8.82) | 18.2507 |
| 2000's | 8 (23.53) | 29.6817 |
| 2010's | 18 (52.94) | 24.3611 |
| 2020's | 3 (8.82) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, N; Kong, Y; Lai, J; Li, J; Li, X; Lyu, N; Zhao, M | 1 |
| Ge, YS; Jia, WD; Wang, RD; Xu, GL; Zhu, JY; Zhu, Y | 1 |
| Banoglu, E; Çalışkan, B; Cetin-Atalay, R; İbiş, K; Kahraman, DC; Nalbat, E | 1 |
| Chow, MD; Guo, GL; Lee, YH | 1 |
| Kainuma, M; Makishima, M; Sano, K; Takada, I | 1 |
| Feng, ZY; Gao, YP; Guo, JG; Guo, XJ; Lu, XY; Rao, YF; Sun, JH; Zhao, LP; Zhou, TY | 1 |
| Augello, G; Azzolina, A; Belmonte, B; Cassata, G; Cervello, M; Cusimano, A; Emma, MR; Gramignoli, R; Gulino, A; McCubrey, JA; Mongiovì, S; Montalto, G; Puleio, R; Strom, SC | 1 |
| Jia, WD; Li, YQ; Lv, JG; Qiao, XF; Zhou, H | 1 |
| Álvarez Santos, MR; Bueno Duarte, Y; Güiza, FM; Mendez-Sanchez, SC; Romero Bohórquez, AR | 1 |
| Briz, O; Herraez, E; Marin, JJ; Muntané, J; Vaquero, J | 1 |
| Hamed, O; Kazem, A; Nasr, M; Selima, E | 1 |
| Chen, WD; Guo, C; Huang, W; Kong, J; Li, C; Li, Y; Long, X; Qi, H; Shen, H; Wang, X; Wang, YD; Yuan, F | 1 |
| Ainiwaer, A; Bao, Y; Cao, Q; Cheng, W; Mao, R; Wu, G; Xiao, L; Yang, Y | 1 |
| Chen, S; Guo, F; He, F; Huang, G; Jiang, P; Lyu, X; Wang, S; Xu, Z; Zeng, Y; Zhang, Y; Zhao, X; Zheng, P | 1 |
| Kong, Y; Lv, N; Mu, L; Pan, T; Xie, Q; Zhao, M | 1 |
| Chen, JB; Chen, JC; Chen, MS; Qiu, HB; Wang, RJ; Xu, L; Zhang, YJ; Zhou, ZG | 1 |
| Alvarez, L; Hierro, L; Jara, P; Martínez-Fernández, P | 1 |
| Ding, W; He, Q; Hu, Y; Liu, T; Wu, R; Yang, B; Zhu, H | 1 |
| Chang, KO; Kim, Y | 1 |
| Kochi, T; Kubota, M; Moriwaki, H; Ohno, T; Sakai, H; Shimizu, M; Shirakami, Y; Tsurumi, H; Yasuda, Y | 1 |
| Albaugh, M; Barbier, M; Collins, JW; Horak, CE; Liewehr, DJ; Marshall, JC; Murone, M; Nakayama, J; Palmieri, D; Steeg, PS; Steinberg, SM; Vidal-Vanaclocha, F | 1 |
| Abel, U; Deuschle, U; Kinzel, O; Kremoser, C; Schlüter, T; Schüler, J; Schulz, A | 1 |
| Suzuki, Y | 1 |
| Blevins, RA; Cui, J; de Pedro, N; Hrywna, Y; Huang, L; Lew, JL; Peláez, F; Thompson, JR; Wright, SD; Yu, J; Zhang, T; Zhao, A | 1 |
| Hultberg, B; Hultberg, M | 1 |
| Bloemendaal, AL; Borel Rinkes, IH; Kranenburg, O; Smakman, N; van Diest, P; Vogten, JM | 1 |
| Casadio, F; Corti, B; Croci, S; D'Errico Grigioni, A; Grigioni, WF; Landuzzi, L; Lollini, PL | 1 |
| Azzolina, A; Cervello, M; Cusimano, A; D'Alessandro, N; Foderà, D; Lampiasi, N; Montalto, G | 1 |
| Weber, G | 1 |
| Kaplowitz, N; Lu, SC; Ookhtens, M; Sze, G | 1 |
| Kato, A; Kubo, K; Matsuzaki, Y; Okita, K; Terai, S | 1 |
| Carretero, J; Estrela, JM; Medina, I; Obrador, E; Ortega, A; Pellicer, JA; Rodilla, V | 1 |
| Sato, M; Stammer, CH | 1 |
| Cnaan, A; Dayal, Y; Falkson, G; Falkson, H; Haller, DG; Simson, IW; Smith, TJ | 1 |
2 review(s) available for isoxazoles and Cancer of Liver
| Article | Year |
|---|---|
The role of bile acids in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.
Topics: Azepines; Bile Acids and Salts; Carcinoma, Hepatocellular; Disease Progression; Energy Metabolism; Gene Expression Regulation; Glucose; Humans; Indoles; Isoxazoles; Liver; Liver Cirrhosis; Liver Neoplasms; Non-alcoholic Fatty Liver Disease; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Receptors, Steroid | 2017 |
Biochemical strategy of cancer cells and the design of chemotherapy: G. H. A. Clowes Memorial Lecture.
Topics: Adenosine Monophosphate; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Deoxyribonucleotides; Gene Expression Regulation; Gluconeogenesis; Guanosine Monophosphate; Humans; Inosine Monophosphate; Isoxazoles; Kidney Neoplasms; Liver Neoplasms; Liver Regeneration; Models, Biological; Neoplasms; Purines; Pyrimidines; Ribonucleotides | 1983 |
5 trial(s) available for isoxazoles and Cancer of Liver
| Article | Year |
|---|---|
Effect and Safety of Prophylactic Parecoxib for Pain Control of Transarterial Chemoembolization in Liver Cancer: A Single-Center, Parallel-Group, Randomized Trial.
Topics: Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Humans; Isoxazoles; Liver Neoplasms; Pain, Postoperative; Prospective Studies | 2022 |
Perioperative analgesia with parecoxib sodium improves postoperative pain and immune function in patients undergoing hepatectomy for hepatocellular carcinoma.
Topics: Analgesics, Opioid; Carcinoma, Hepatocellular; Hepatectomy; Humans; Immunity; Isoxazoles; Liver Neoplasms; Pain, Postoperative | 2020 |
Effectiveness of Parecoxib Sodium Combined with Transversus Abdominis Plane Block for Pain Management After Hepatectomy for Hepatocellular Carcinoma: A Prospective Controlled Study.
Topics: Abdominal Muscles; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, Local; Carcinoma, Hepatocellular; China; Female; Hepatectomy; Humans; Isoxazoles; Liver Neoplasms; Male; Middle Aged; Nerve Block; Pain Management; Pain Measurement; Pain, Postoperative; Postoperative Complications; Prospective Studies; Ropivacaine | 2019 |
Effect of perioperative parecoxib sodium on postoperative pain control for transcatheter arterial chemoembolization for inoperable hepatocellular carcinoma: a prospective randomized trial.
Topics: Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazoles; Liver Neoplasms; Male; Middle Aged; Pain, Postoperative; Perioperative Care; Prospective Studies; Treatment Outcome | 2016 |
A randomized phase II study of acivicin and 4'deoxydoxorubicin in patients with hepatocellular carcinoma in an Eastern Cooperative Oncology Group study.
Topics: Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Doxorubicin; Drug Administration Schedule; Female; Humans; Isoxazoles; Liver Neoplasms; Male; Prospective Studies; Survival Rate | 1990 |
27 other study(ies) available for isoxazoles and Cancer of Liver
| Article | Year |
|---|---|
Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells.
Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Isoxazoles; Liver Neoplasms; Molecular Structure; Piperazine; Structure-Activity Relationship; Tumor Cells, Cultured | 2021 |
Farnesoid X Receptor Activation Enhances Transforming Growth Factor β-Induced Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma Cells.
Topics: Bile Acids and Salts; Cadherins; Carcinoma, Hepatocellular; Cell Line, Tumor; Chenodeoxycholic Acid; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Isoxazoles; Liver; Liver Neoplasms; Receptors, Cytoplasmic and Nuclear; Transforming Growth Factor beta1 | 2018 |
Novel multimodal analgesia regimen improves post-TACE pain in patients with hepatocellular carcinoma.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cost-Benefit Analysis; Female; Health Care Costs; Humans; Isoxazoles; Liver Neoplasms; Male; Middle Aged; Pain, Postoperative; Patient Satisfaction; Postoperative Nausea and Vomiting; Sufentanil | 2018 |
Targeting HSP90 with the small molecule inhibitor AUY922 (luminespib) as a treatment strategy against hepatocellular carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; beta Catenin; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Hep G2 Cells; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Liver Neoplasms; Male; Mice, Nude; Middle Aged; Mutation; Resorcinols; Small Molecule Libraries; Transcriptome; Up-Regulation | 2019 |
Effects of new tetrahydroquinoline-isoxazole hybrids on bioenergetics of hepatocarcinoma Hep-G2 cells and rat liver mitochondria.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Survival; Energy Metabolism; Hep G2 Cells; Humans; Isoxazoles; Liver Neoplasms; Male; Mitochondria, Liver; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Oxidative Stress; Quinolines; Rats; Rats, Wistar | 2019 |
Activation of the nuclear receptor FXR enhances hepatocyte chemoprotection and liver tumor chemoresistance against genotoxic compounds.
Topics: Antineoplastic Agents; Biomarkers, Tumor; Cell Survival; Cells, Cultured; Cisplatin; Drug Resistance, Neoplasm; Gene Expression Profiling; Hepatocytes; Humans; Isoxazoles; Liver Neoplasms; Luciferases; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA-Binding Proteins; RNA, Messenger; Transcription, Genetic; Transcriptional Activation | 2013 |
Targeting different angiogenic pathways with combination of curcumin, leflunomide and perindopril inhibits diethylnitrosamine-induced hepatocellular carcinoma in mice.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antineoplastic Agents; Antirheumatic Agents; Carcinogens; Carcinoma, Hepatocellular; Curcumin; Diethylnitrosamine; Drug Therapy, Combination; Hypoxia-Inducible Factor 1, alpha Subunit; Isoxazoles; Leflunomide; Liver; Liver Neoplasms; Male; Mice; Neovascularization, Pathologic; Perindopril; Platelet Endothelial Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A | 2014 |
Farnesoid X receptor antagonizes JNK signaling pathway in liver carcinogenesis by activating SOD3.
Topics: Animals; Antioxidants; Base Sequence; Carcinogenesis; Enzyme Activation; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Hepatocytes; Humans; Isoxazoles; JNK Mitogen-Activated Protein Kinases; Liver; Liver Neoplasms; Male; MAP Kinase Signaling System; Mice; Molecular Sequence Data; Oxidants; Phosphorylation; Promoter Regions, Genetic; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Superoxide Dismutase; Up-Regulation | 2015 |
Role of the novel HSP90 inhibitor AUY922 in hepatocellular carcinoma: Potential for therapy.
Topics: Adult; Aged; Carcinoma, Hepatocellular; Case-Control Studies; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Diffusion Chambers, Culture; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Hep G2 Cells; HSP90 Heat-Shock Proteins; Humans; Isoxazoles; Liver Neoplasms; Male; Middle Aged; Neovascularization, Pathologic; Resorcinols; Signal Transduction | 2015 |
FXR induces SOCS3 and suppresses hepatocellular carcinoma.
Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Chromatin Immunoprecipitation; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Immunohistochemistry; Isoxazoles; Liver Neoplasms; Mice; Mice, Nude; Real-Time Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear; RNA, Small Interfering; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Transfection; Xenograft Model Antitumor Assays | 2015 |
Parecoxib prevents complications in hepatocellular carcinoma patients receiving hepatic transarterial chemoembolization: a prospective score-matched cohort study.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cyclooxygenase 2 Inhibitors; Female; Fever; Humans; Isoxazoles; Length of Stay; Liver; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Palliative Care; Postoperative Nausea and Vomiting; Propensity Score; Prospective Studies | 2016 |
Knockdown of ATP8B1 expression leads to specific downregulation of the bile acid sensor FXR in HepG2 cells: effect of the FXR agonist GW4064.
Topics: Adenosine Triphosphatases; Bile Acids and Salts; Cell Line, Tumor; DNA-Binding Proteins; Down-Regulation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Hepatoblastoma; Humans; Isoxazoles; Liver Neoplasms; Phosphorylation; Receptors, Cytoplasmic and Nuclear; RNA Interference; RNA, Small Interfering; Transcription Factors; Transfection | 2009 |
XN05, a novel synthesized microtubule inhibitor, exhibits potent activity against human carcinoma cells in vitro.
Topics: Acetamides; Apoptosis; Carcinoma, Hepatocellular; Caspases; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Inhibitory Concentration 50; Isoxazoles; Liver Neoplasms; Microtubules; Phosphorylation; Protein Multimerization; Proto-Oncogene Proteins c-bcl-2; Stilbenes; Time Factors; Tubulin; Tubulin Modulators | 2009 |
Inhibitory effects of bile acids and synthetic farnesoid X receptor agonists on rotavirus replication.
Topics: Animals; Blotting, Western; Caco-2 Cells; Carcinoma, Hepatocellular; Chenodeoxycholic Acid; Female; Gastrointestinal Agents; Humans; Isoxazoles; Liver Neoplasms; Mice; Mice, Inbred BALB C; Real-Time Polymerase Chain Reaction; RNA-Binding Proteins; RNA, Messenger; Rotavirus; Rotavirus Infections; Triglycerides; Tumor Cells, Cultured; Virus Replication | 2011 |
Synergistic growth inhibition of human hepatocellular carcinoma cells by acyclic retinoid and GW4064, a farnesoid X receptor ligand.
Topics: Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Humans; Isoxazoles; Liver Neoplasms; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Retinoids | 2012 |
Effect of inhibition of the lysophosphatidic acid receptor 1 on metastasis and metastatic dormancy in breast cancer.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Proliferation; eIF-2 Kinase; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Isoxazoles; Ki-67 Antigen; Liver Neoplasms; Lung Neoplasms; Mammary Neoplasms, Experimental; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Nude; NM23 Nucleoside Diphosphate Kinases; Propionates; Random Allocation; Receptors, Lysophosphatidic Acid; RNA, Small Interfering | 2012 |
FXR controls the tumor suppressor NDRG2 and FXR agonists reduce liver tumor growth and metastasis in an orthotopic mouse xenograft model.
Topics: Animals; Binding Sites; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Hep G2 Cells; Humans; Isoxazoles; Liver; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Neoplasm Metastasis; Protein Binding; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tumor Burden; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2012 |
[Anti-rheumatic drugs].
Topics: Antirheumatic Agents; Cysteine; Hematologic Diseases; Humans; Hypersensitivity; Infections; Isoxazoles; Kidney Diseases; Leflunomide; Liver Neoplasms; Lung Diseases; Methotrexate | 2012 |
Human kininogen gene is transactivated by the farnesoid X receptor.
Topics: Binding Sites; Blotting, Northern; Carcinoma, Hepatocellular; Chenodeoxycholic Acid; DNA; DNA-Binding Proteins; Gene Deletion; Gene Expression Regulation; Hepatocytes; Humans; Isoxazoles; Kininogens; Liver Neoplasms; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Repetitive Sequences, Nucleic Acid; Retinoid X Receptors; RNA, Messenger; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2003 |
High glutathione turnover in human cell lines revealed by acivicin inhibition of gamma-glutamyltranspeptidase and the effects of thiol-reactive metals during acivicin inhibition.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cysteine; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutathione; HeLa Cells; Humans; Isoxazoles; Liver Neoplasms; Metals; Sulfhydryl Compounds | 2004 |
Cyclooxygenase-2 is a target of KRASD12, which facilitates the outgrowth of murine C26 colorectal liver metastases.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Genes, ras; Image Processing, Computer-Assisted; Immunohistochemistry; Isoxazoles; Ki-67 Antigen; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Microcirculation; Mutation; Neoplasm Metastasis; Neoplasm Transplantation; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins p21(ras); RNA Interference; Time Factors | 2005 |
Toward the definition of immunosuppressive regimens with antitumor activity.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Isoxazoles; Jurkat Cells; Leflunomide; Liver Neoplasms; Mycophenolic Acid; Rhabdomyosarcoma; Sirolimus | 2005 |
Potentiation of the antitumor effects of both selective cyclooxygenase-1 and cyclooxygenase-2 inhibitors in human hepatic cancer cells by inhibition of the MEK/ERK pathway.
Topics: Apoptosis; Blotting, Western; Butadienes; Carcinoma, Hepatocellular; Caspases; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytochromes c; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Flow Cytometry; Humans; Isoxazoles; Liver Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Nitriles; Phosphorylation; Pyrazoles; Sulfones; Time Factors; Tumor Cells, Cultured | 2007 |
Bidirectional membrane transport of intact glutathione in Hep G2 cells.
Topics: Biological Transport; Bucladesine; Cell Line; Cell Membrane; Cholera Toxin; gamma-Glutamyltransferase; Glutathione; Hepatoblastoma; Homeostasis; Humans; Isoxazoles; Kinetics; Liver; Liver Neoplasms; Sulfobromophthalein; Tumor Cells, Cultured | 1993 |
Antitumor effect of vesnarinone on human hepatocellular carcinoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Division; Dose-Response Relationship, Drug; Humans; In Situ Nick-End Labeling; Isoxazoles; Liver Neoplasms; Pyrazines; Quinolines; Tumor Cells, Cultured | 1999 |
gamma-Glutamyl transpeptidase overexpression increases metastatic growth of B16 melanoma cells in the mouse liver.
Topics: Animals; Brain; Buthionine Sulfoximine; Cell Division; Enzyme Inhibitors; Erythrocytes; gamma-Glutamyltransferase; Gene Expression; Glutathione; Hepatocytes; Humans; Isoxazoles; Kidney; Liver; Liver Neoplasms; Lung; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Transfection; Tumor Cells, Cultured | 2002 |
5-Carboxamido-4-amino-3-isoxazolidone, and asparagine analogue.
Topics: Animals; Antineoplastic Agents; Aspartate-Ammonia Ligase; Carcinoma, Hepatocellular; Isoxazoles; Leukemia L1210; Leukemia, Experimental; Liver Neoplasms; Mice; Neoplasms, Experimental; Oxazoles; Oxazolidinones | 1978 |